Abbott AEROSET User manual

System
Troubleshooting
Guide
Abbott Laboratories
Abbott Park, IL 60064
94816-107—November 2004
©1998, 2004 Abbott Laboratories
AEROSET is a Registered Trademark of
Abbott Laboratories

PROPRIETARY INFORMATION
CONFIDENTIAL MATERIAL
Not for Customer Distribution
2AEROSET® System Troubleshooting Guide
94816-107—November 2004
NOTES

PROPRIETARY INFORMATION
CONFIDENTIAL MATERIAL
Not for Customer Distribution
AEROSET® System Troubleshooting Guide 3
94816-107—November 2004
Revision Status
Document Control
Number(s)
Revision Date Section(s)
Revised
Pages Revised and
Added
30-0897/R1 9/98 Original Issue Original Issue
30-1762/R2 1/00 All Sections All Pages
94816-101 6/01 All Sections All Pages
94816-102 4/02 All Sections All Pages
94816-103 6/02 All Sections All Pages
94816-104 2/03 All Sections All Pages
94816-105 6/03 All Sections All Pages
94816-106 12/03 All Sections All Pages
94816-107 11/04 All Sections All Pages

PROPRIETARY INFORMATION
CONFIDENTIAL MATERIAL
Not for Customer Distribution
4AEROSET® System Troubleshooting Guide
94816-107—November 2004
Highlights of Changes from Previous AEROSET System
Troubleshooting Guide (94819-106)
NOTE: This section is intended as a guide to highlight
major and significant changes to this version of the
AEROSET System Troubleshooting Guide, Part
Number 94816-107. It is NOT intended to be a
comprehensive description of all changes to the guide
and/or AEROSET System functionality, hardware, and
reagent applications.
Overview
• The organization of the Assays/Reagents section of the
AEROSET System Troubleshooting Guide was updated;
it is now divided into General Information and
Assay-specific Information subsections.
1. If troubleshooting information for a specific assay is
available, it is listed alphabetically in Assay-specific
Information. If an assay-specific subsection does not
exist, no additional troubleshooting information is
currently available.
2. Previously, some assays, e.g., MULTIGENT® assays,
included Assay-specific Questions sections. These
Question and Answer sections were expanded and
renamed Frequently Asked Questions (FAQ).
• The Question and Answer format of some sections in the
Troubleshooting Guide was eliminated, with the
exception of assay-specific Frequently Asked Questions
(FAQ).
• Procedures to verify Limit of Detection (LOD) and Limit of
Quantitation (LOQ) were consolidated into one
subsection, Verification Procedures in Assays/Reagents,
General Information.
• Assay-specific cross reactivity information for Drugs of
Abuse (DOA) assays is now located in Assay-specific
Information.

PROPRIETARY INFORMATION
CONFIDENTIAL MATERIAL
Not for Customer Distribution
AEROSET® System Troubleshooting Guide 5
94816-107—November 2004
• Some information previously included in the
Troubleshooting Guide was eliminated because it
duplicated information that is readily available to
customers in other secondary labeling, e.g., Abbott
Clinical Chemistry Package inserts or the AEROSET
System Operations Manual. Major sections that were
eliminated include:
1. Specific SmartWash™ parameters
2. Specific method comparison, interference, and limit
of detection information for DOA assays
3. Specimen collection requirements for MULTIGENT®
assays
Specific Changes and/or New Information
• Mercury warning symbol and information added.
• New information for the C-Reactive Protein and
Rheumatoid Factor assays added to Assays/Reagents,
Assay-specific Information.
• Information for the MULTIGENT Microalbumin assay
added to Assays/Reagents, Assay-specific Information.
The chemical reaction for MULTIGENT Microalbumin
added to Chemical Reactions for Clinical Chemistry Assays.
• New information for the Specific Proteins assays added to
both the Assays/Reagents, General Information and
Assays/Reagents, Assay-specific Information sections.
• Product information for Abbott Clinical Chemistry
calibrators added.
• A list of applicable assays for each control was added to the
Bio-Rad Control Products information table.
• A general Specimen Collection and Handling section was
created by consolidating various assay-specific
information in the previous Troubleshooting Guide.
• Additional information for the Therapeutic Drug
Monitoring (TDM) assays, including Frequently Asked
Questions (FAQ), added to Assays/Reagents, General
Information.
• CK assay—explanation of issues with FlexRate™ linearity.