Agilent Technologies K6460 Installation and operating manual

Agilent 6460 Triple Quad Mass
Spectrometer (Model K6460)
Safety Guide
For In Vitro Diagnostic Use
Safety 2
Symbols on Instruments 2
General Instrument Safety 5
Physical Hazard Safety 6
General Chemical Safety 9
Chemical Waste Safety 10
Biohazard Safety 11
Conformity and Standards 12
Safety and Regulatory Certifications 12
Electromagnetic Compatibility 13
Environmental Conditions 14
Sound Emission Declaration 14
This guide contains information about safety, conformity and standards for
your Agilent 6460 Triple Quad Mass Spectrometer (Model K6460).
WARNING Always wear appropriate protection, including eye protection, lab coat, and gloves,
when working with solvents and chemicals or when working with unassembled
parts.

Safety
Symbols on Instruments
2 K6460 Triple Quad MS Safety Guide
Safety
Symbols on Instruments
Electrical symbols
The following table describes the electrical symbols that can be displayed on
the K6460 mass spectrometer.
Table 1 Electrical symbols
Symbol Description
Indicates a protective earth terminal.
Indique une borne de terre de protection.
Circuit breaker.
Disjoncteur.
Alternating current
Courant alternatif
Fuse
Fusible

Safety
Symbols on Instruments
K6460 Triple Quad MS Safety Guide 3
Safety symbols
The following table describes the safety symbols that can be displayed on the
K6460 mass spectrometer. Each symbol appears by itself or with text that
explains the relevant hazard. These safety symbols can also appear next to
DANGER, WARNING, or CAUTION.
Table 2 Safety symbols
Symbol Description
or
The apparatus is marked with this symbol when the
user should refer to the instruction manual in order
to protect against harm to the operator and to
protect the apparatus against damage.
L'appareil est marqué avec ce symbole lorsque
l'utilisateur doit se référer au manuel d'instruction
afin de protéger contre les atteintes à l'opérateur et
pour protéger l'appareil contre les dommages.
Indicates dangerous voltages.
Indique des tensions dangereuses.
The apparatus is marked with this symbol when hot
surfaces are accessible and the user should not
touch them when heated up.
L'appareil est marqué avec ce symbole lorsque les
surfaces chaudes sont accessibles et que
l'utilisateur ne doit pas les toucher lorsqu'elles sont
chaudes.
Electric discharge (ESD) hazard to equipment.
Risque de décharge électrique à l'équipement
Explosion hazard.
Risque d'explosion

Safety
Symbols on Instruments
4 K6460 Triple Quad MS Safety Guide
Do not operate the instrument in the presence of
hydrogen or any other flammable gases or fumes.
Operation of any electrical instrument in such an
environment constitutes a definite safety hazard.
Ne pas utiliser l'instrument en présence de gaz ou de
vapeurs inflammables. L'utilisation de tout
instrument électrique dans un tel environnement
constitue un danger certain.
Do not discard this electrical/electronic product in
domestic household waste.
Ne jetez pas ce produit électrique / électronique
avec les ordures ménagères.
Disconnect main plug from electrical outlet prior to
fuse replacement.
Débranchez la prise principale de la prise électrique
avant de remplacer le fusible.
Two live circuits. Disconnect both power cords
before maintenance.
Deux circuits sous tension. Débranchez les deux
cordons d'alimentation avant l'entretien.
Biological risks
Dangers biologiques
Table 2 Safety symbols (continued)
Symbol Description

Safety
General Instrument Safety
K6460 Triple Quad MS Safety Guide 5
General Instrument Safety
Moving or lifting the system
Operating the instrument
Before you operate the instrument, make sure that you have:
•Been given instructions on general safety practices for laboratory and
specific safety practices for the instrument.
•Read and understood all material safety data sheets (MSDS) for chemicals
handled.
WARNING PHYSICAL INJURY HAZARD: Use the K6460 mass spectrometer only as specified in
the user instructions. Using the system in a manner not specified by Agilent
Technologies can result in personal injury or damage to the instrument.
WARNING PHYSICAL INJURY HAZARD: The K6460 mass spectrometer is heavy. The K6460
mass spectrometer requires at least four people to lift. Check your local regulations
for the maximum weight that each person can lift.

Safety
Physical Hazard Safety
6 K6460 Triple Quad MS Safety Guide
Physical Hazard Safety
Solvents
Electrical safety
WARNING PHYSICAL INJURY HAZARD: Always wear appropriate protection, including eye
protection and gloves, when working with solvents and chemicals. Refer to the
applicable MSDS for more information about the materials you are working with.
WARNING When the K6460 mass spectrometer is plugged into a power source, even if the
power switch is off, dangerous voltages can exist:
• In the wiring between the K6460 mass spectrometer power cord and the AC
power supply.
• In the AC power supply
• In the wiring from the AC power supply to the power switch.
WARNING Never remove a cover unless specifically instructed to do so. With the power
switch on, potentially dangerous voltages can exist:
• On all electronics boards in the instrument.
• In the internal wires and cables connected to these boards.
• In the wires for any heater.
CAUTION The printed circuit (PC) boards in the K6460 mass spectrometer can be damaged by
electrostatic discharge. Do not touch any of the boards unless absolutely necessary. If
you must handle the PC boards, wear a grounded wrist strap and take other anti-static
precautions. Wear a grounded wrist strap any time you must remove the K6460 mass
spectrometer covers.

Safety
Physical Hazard Safety
K6460 Triple Quad MS Safety Guide 7
WARNING Severe electrical shock can result from operating the K6460 mass spectrometer
without the correct Agilent power cords in place.
Grounding circuit continuity is required for the safe operation of equipment.
Use properly configured and approved line cords for the voltage supply in your
facility. Refer to the Site Prep Guide for details.
WARNING If the power cord insulation is damaged, frayed, or worn, replace the cord. Contact
your Agilent representative.
WARNING Plug the K6460 mass spectrometer AC input power cords into properly grounded
receptacles with adequate current capacity. The branch circuit over-current
protection Circuit Breakers protecting the building receptacles must be rated no
more than 20A.
WARNING Be sure that the LC/MS main supply cable is routed in such a way as to minimize
the risk of a tripping hazard. Agilent Technologies recommends the use of
mechanical protection, such as a rubberized cable guard on the floor to cover and
protect the main supply cable.
WARNING Make sure that the point at which the detachable power cords are connected to the
K6460 mass spectrometer is clear from clutter and that it is accessible at all times.
WARNING Do not interrupt the protective conductor inside or outside the LC/MS system or
disconnect the protective earth terminal. Such actions create a shock hazard for the
operator and can damage the instrument.

Safety
Physical Hazard Safety
8 K6460 Triple Quad MS Safety Guide
Temperature safety
WARNING The use of incorrect or makeshift fuses or the short-circuiting of fuse holders
creates a shock hazard for the operator and can damage the instrument. Replace
fuses only with fuses of identical current rating and type. Refer to the Maintenance
Guide for more information.
WARNING Excessive fluctuations in the line voltage can create a shock hazard and can
damage the instrument. This equipment must be installed in a Category II
environment as defined in IEC 664.
For all instruments, the supply voltage must not fluctuate more that ±10%.
For any instrument with an Agilent Jet Stream source, the line voltage must not
fluctuate more that +10/-5% from the rated voltage.
WARNING Some parts of the K6460 mass spectrometer operate at temperatures high enough
to cause serious burns. Always cool heated parts of the LC/MS down to room
temperature before you work on them.
To cool the instrument faster, set the heated zone to room temperature. Turn the
zone off after it has reached the set point.
If you must do maintenance work on a hot part, use a wrench and wear gloves.

Safety
General Chemical Safety
K6460 Triple Quad MS Safety Guide 9
General Chemical Safety
To minimize the hazards of chemicals:
•Read and understand the MSDS provided by the manufacturer before you
store, handle, or work with any chemicals or hazardous materials.
•Minimize contact with chemicals. Wear appropriate personal protective
equipment when handling chemicals (for example, safety glasses, gloves, or
protective clothing).
•Minimize the inhalation of chemicals. Do not leave chemical containers
open. Use only with adequate ventilation (for example, fume hood).
•Check regularly for chemical leaks or spills. If either of those occur, follow
the cleanup procedures from the manufacturer, as recommended in the
MSDS.
•Comply with all local, state/provincial, or national laws and regulations
related to chemical storage, handling, and disposal.
WARNING CHEMICAL HAZARD: Before handling any chemicals, refer to the Material Safety
Data Sheet (MSDS) provided by the manufacturer, and observe all relevant
precautions.

Safety
Chemical Waste Safety
10 K6460 Triple Quad MS Safety Guide
Chemical Waste Safety
To minimize the hazards of chemical waste:
•Read and understand the MSDS provided by the manufacturers of the
chemicals in the waste container before you store, handle, or dispose of
chemical waste.
•Provide primary and secondary waste containers. Both containers must be
compatible with the waste material and meet federal, state/provincial, and
local requirements for container storage.
•Minimize contact with chemicals. Wear appropriate personal protective
equipment when handling chemicals (for example, safety glasses, gloves, or
protective clothing).
•Minimize the inhalation of chemicals. Do not leave chemical containers
open.
•Handle chemical wastes in a fume hood.
•After emptying a waste container, seal it with the cap provided.
•Dispose of the contents of the waste tray and waste bottle in accordance
with good laboratory practices and local, state / provincial, or national
environmental and health regulations.
•Ensure that the K6460 mass spectrometer waste is stored, transferred,
transported, and disposed of according to all local, state / provincial,
and/or national regulations.
WARNING CHEMICAL WASTE HAZARD: Wastes produced by the MS System are potentially
hazardous and can cause injury, illness, or death. Refer to Material Safety Data
Sheets and local regulations for handling and disposal.
WARNING CHEMICAL WASTE HAZARD: The foreline pump and source exhaust contain traces
of the chemicals that you are analyzing. The exhaust products can be toxic. Vent the
pump and source exhaust outside your laboratory or into a fume hood. Make sure to
comply with all local environmental regulations.