Avacen 100 User manual

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User Guide
Model AVACEN 100
Caution: Please read the entire user guide with care prior to using the device.
AVACEN is a Registered Trademark of AVACEN Medical, Inc.
Protected by one or more of the following U.S. patents: 8,679,170; 9,066,781; 9,192,509;
9,687,385; 10,537,464; international equivalents. Other patents pending.
AVACEN Medical
2365 Camino Vida Roble, Ste. C
Carlsbad, CA 92011
(888) 4-AVACEN (888-428-2236)
www.AVACEN.com
THE QUICK START GUIDE IS ON BACK COVER

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OK/Accept/
Confirm/
Select ✔
Display Panel
ON/OFF Silicone Seal for
Vacuum Chamber
Inflatable Cuff
Metal
Heatpad
Pressure Holes
Power Supply Connector
Hand Positioning Tips: KEEP WRIST STRAIGHT AND IN THE CENTER OF THE CUFF!
POSITION WRIST
IN MIDDLE OF CUFF
PARALLEL
WITH CHAMBER
CORRECT
CORRECT
INCORRECT
INCORRECT
Power
Plug
Up
Down
Left Right
AVACEN Device Diagram
Vacuum Chamber
Screws
Sanitary Mitt
Metal
Heatpad

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Table of Contents
1. DESCRIPTION ....................................................................................................................... 1
2. UNPACKING THE UNIT ........................................................................................................ 1
3. NORMAL USE ...................................................................................................................... 1
4. INDICATIONS FOR USE ........................................................................................................ 1
5. CONTRA-INDICATIONS ........................................................................................................ 1
6. WARNINGS & PRECAUTIONS .............................................................................................. 2
7. IMPORTANT SAFETY INFORMATION ................................................................................... 3
8. CONTACT INFORMATION .................................................................................................... 4
9. EXPLANATION OF SYMBOLS................................................................................................ 4
10. OPERATING INSTRUCTIONS (NORMAL MODE OPERATION) .............................................. 5
11. CUFF SEALING .................................................................................................................... 7
12. HAND PRESSURE INDICATOR (HPI) .................................................................................... 7
13. PAUSING A THERAPY SESSION ............................................................................................ 8
14. ADJUSTING THE THERAPY TIME .......................................................................................... 8
15. ADJUSTING THE THERAPY TEMPERATURE.......................................................................... 8
16. END OF THERAPY ................................................................................................................ 8
17. POWERING DOWN .............................................................................................................. 8
18. STANDBY MODE OPERATION .............................................................................................. 9
19. GAME MODE OPERATION ................................................................................................... 9
20. TROUBLESHOOTING AND FAQ .......................................................................................... 11
A. How long should treatment last? ...................................................................................... 11
B. How important is the placement of my hand? .................................................................. 11
C. Is it necessary to wear the AVACEN Mitt? ......................................................................... 11
D. Do I need a new a Mitt every time I have a treatment? ................................................... 11
E. Do I need to purchase the Mitts from AVACEN? ............................................................... 11
F. The AVACEN unit powers down while the 'Sealing Cuff' message or 'Lost Vacuum Seal'
message is displayed ......................................................................................................... 12
G. "Rest Palm On Heatpad" message ..................................................................................... 12
H. "Calibration Failed" message ............................................................................................. 13
I. "System Error" Message .................................................................................................... 13
J. There is noise while the AVACEN device is running .......................................................... 13
K. The inflatable cuff is too tight ............................................................................................ 13
L. I keep getting a "Push Hand Down Slightly" or "Lift Hand Slightly" message ................... 14
M. The AVACEN Heatpad is too hot (or too cool) ................................................................... 14
N. The Heatpad seems "loose" ............................................................................................... 14
O. The Display Panel Power LED does not illuminate after pushing the ON Button ............. 15

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P. Checking the inflatable cuff for leaks ................................................................................. 15
Q. Excessive swelling of the hand ........................................................................................... 15
R. Red or purple spots on the hand ........................................................................................ 15
S. Hand itches or tingles ......................................................................................................... 15
T. My hand is reddish-colored like it has been in hot water .................................................. 15
U. Sweating when using the AVACEN ..................................................................................... 15
V. Discomfort in wrist or forearm during use ......................................................................... 15
21. USER SETTINGS .................................................................................................................. 16
A. Language Selection ............................................................................................................. 16
B. Beep Tone Style .................................................................................................................. 16
C. Default Therapy Session Time ............................................................................................ 16
D. Default Therapy Session Temperature ............................................................................... 17
E. Display Error Messages ....................................................................................................... 17
F. Measure Hand Pad Force .................................................................................................... 17
G. Run Self-Sealing Test ........................................................................................................... 17
22. CLEANING ........................................................................................................................... 19
23. PERIODIC MAINTENANCE .................................................................................................. 19
Removing the Vacuum Chamber ............................................................................................... 19
Removing the Seal ..................................................................................................................... 20
Installing the Seal ....................................................................................................................... 20
Installing the Vacuum Chamber ................................................................................................ 21

210116
AVACEN 100 User Guide 1
1. DESCRIPTION
The AVACEN 100 is a Dry Heat Therapy FDA Class II Medical Device. It consists of a control panel,
metal Heatpad, and a Vacuum Chamber with an Inflatable Cuff. The vacuum pump and heat
source are in the base of the unit. For proper function and to maintain sanitary conditions, the
AVACEN device MUST be used with the supplied hand mitts. Extra hand mitts can be purchased
by contacting AVACEN at: [e-mail]
2. UNPACKING THE UNIT
The shipping box contains the AVACEN device, power cord, power supply, mitts, and this user
guide. Lift the top shipping foam piece out of the box. Then lift the AVACEN out of the box with
two hands. Keep the shipping box and foam in case the AVACEN needs to be returned. Be sure
to read the What to Expect flyer before the first use.
3. NORMAL USE
The AVACEN is designed to provide dry heat therapy. Treatment time and/or number of uses per
day can be increased based on professional recommendations or absence of response to
treatment. Proposed use is: 15 minutes first thing in the morning using the LEFT hand (hint: "Left
is for day Light") and 15 minutes before bed using the RIGHT hand (hint: "Right is for Night")
healthy hand condition permitting.
Any level of major discomfort (after lowering Heat setting first) is not normal. If this happens,
stop using the AVACEN right away and report the problem to AVACEN Medical Customer
Service at (888) 4-AVACEN (888-428-2236) or send an email to: Custome[email protected]
4. INDICATIONS FOR USE
The AVACEN 100 is a heat therapy system indicated for the temporary relief of minor muscle and
joint pain and stiffness; the temporary relief of joint pain associated with arthritis, muscle
spasms, minor strains and sprains; muscular relaxation; and the temporary increase of local
circulation where applied.
5. CONTRA-INDICATIONS
Although there has been no issues reported, it is suggested that you contact a doctor before
using the AVACEN if you are under 18 years of age, are pregnant, or have a temperature higher
than 99.5°F (37.5°C). Do not use the AVACEN on a hand that has open sores or wounds.

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210116
6. WARNINGS & PRECAUTIONS
WARNINGS are used to signal potential hazards which could lead to death or serious injury.
PRECAUTIONS are used to warn the reader of potential hazardous situations. If not avoided,
these hazards may result in minor or moderate injury to the user or patient or damage to the
device or other property.
Warnings
 This device IS NOT meant to provide ample heating where the internal body core
temperature is falling uncontrollably, or is lower than 95F (35C). In these cases, GET
MEDICAL ATTENTION FAST!
 Making changes to this device is not allowed.
 Do not use the AVACEN with other devices or accessories except as described in this User
Guide.
 Choking Hazard - contains small parts. Keep out of reach of children.
 Strangulation Hazard - contains a long power cord that may cause strangulation if used
improperly. Keep out of reach of small children.
Precautions
 The following cautions are guidelines only and are not meant to replace a health care
professional’s advice. If any harmful effect occurs while using the product, stop use and
contact your health care professional.
 Use with care. May cause serious burns. Do not use on over sensitive skin areas or in the
presence of poor circulation.
 The unattended use of the AVACEN by children or incapacitated persons may be
dangerous.
 Do not use with liniment, salve or ointments - May cause skin irritation.
 To prevent damage to the mitt and inflatable cuff: remove all jewelry (rings, bracelets,
watches) from the hand that will be used for therapy.
 Do not use the AVACEN on a hand that has open sores or wounds. Any level of major
discomfort (after lowering temperature first) is not normal.
 Metal implants - pay attention for signs of any uncomfortable heat buildup in the
treatment area. If this occurs, stop using the device.
 Stop using the AVACEN right away and report any major discomfort problems to AVACEN
Medical customer support at (888) 4-AVACEN (888-428-2236) or email AVACEN Medical
at CustomerServic[email protected]
 To remove your hand from the Vacuum Chamber at any time, turn the unit Off. During
the power down process the air will be automatically drained from the cuff so that your
hand can be removed easily.
 If the unit does not turn off when the On/Off Button is pressed, unplug the unit. The air
will drain from the cuff as you slowly pull your hand out of the device.
 Although there have been no issues reported, consult your healthcare professional before
using the AVACEN if you have any of the following:.
 Malignancy (A term for diseases in which abnormal cells divide without control and
can invade nearby tissues) .
 Pregnancy.
 Chronically hot or swollen joint in the hand, fingers, or wrist.
 Circulatory diseases.
 Recent acute joint injury in the hand, fingers, or wrist.

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AVACEN 100 User Guide 3
7. IMPORTANT SAFETY INFORMATION
 Read the entire AVACEN device User Guide before using this device.
 For continued protection against risk of fire and shock, use the hand unit only with the
provided power supply, AVACEN part number 50-100000.
 Do not store the AVACEN device in direct sunlight. The AVACEN should be stored in a clean,
well-ventilated area at room temperature. Keep out of reach of small children and pets.
Optional carrying bags should be left open to allow ventilation.
 Do not use outdoors in the rain, snow, or under water. While the device is protected against
vertically dripping water, it is not water resistant, and should not be used in wet areas.
 Pressing too hard on the heat pad can cause the AVACEN to be ineffective.
 The Power Supply Connector is the main power disconnect device for the AVACEN device. If
the unit does not turn off when the On/Off Button is pressed or a malfunction is suspected,
unplug the power supply or remove the power input from the unit.
 This device complies with Part 18 of the FCC Rules, as well as international electromagnetic
compatibility requirements. Use is subject to these two conditions:.
1) This device may not cause harmful interference. 2) This device must accept any
interference received, including interference that may cause undesired operation.
These limits are designed to provide reasonable protection against harmful interference in a
residential installation. However, there is no guarantee that interference will not occur in a
particular installation. If this equipment causes problems with radio or TV reception, which
can be checked by turning the equipment off and on, you are encouraged to try to correct the
interference by one or more of the following measures:.
• Reorient the receiving antenna.
• Relocate the system with respect to the receiver.
• Move the system away from the receiver.
• Plug the system into a different outlet so that the system and the receiver are on different
branch circuits.
Environmental Conditions
Temperature Operating
50F (10°C) to 104F
(40°C)
Storage
32F (0°C) to 140F (60°C)
Relative
Humidity
Operating 30 to 75% rH
Storage 10 to 95% rH
Atmospheric
Pressure
Operating 700 to 1060hPa
Storage 500 to 1060hPa
AC Input Voltage 100-240V~, 50-60Hz
Expected service life of equipment
and accessories 5 years

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210116
8. CONTACT INFORMATION
Manufacturer:
AVACEN Medical
2365 Camino Vida Roble, Suite C
Carlsbad, CA 92011
Phone: (888) 4-AVACEN (888-428-2236)
web: AVACEN.com
Email: [e-mail]
9. EXPLANATION OF SYMBOLS
Symbol Description
ON/OFF Pushbutton Switch
✔
OK/Accept/Confirm/Select Pushbutton Switch
▲▼◄►
Up / Down / Left / Right Function Select Pushbuttons
▂▅▇
Low/Medium/High Temperature Settings
Remove all jewelry and watch before inserting hand in the device. Do
not allow your shirt sleeve to enter into the Inflatable Cuff.
Caution: Refer to Instructions
Read Instruction Manual
Atmospheric Pressure Range
Temperature Range
Humidity Range
IP21 Protection rating for ingress of solid objects and water: protected
against solid objects larger than 12.5 mm and vertically dripping
water
Type BF Applied Part (model AVACEN 100 only)
Do Not Dispose in Trash
Identification of Manufacturer
Indicates compliance to European Directives
Complies with 47 CFR Part 18 for Industrial, Scientific, and Medical
Equipment

210116
AVACEN 100 User Guide 5
10. OPERATING INSTRUCTIONS (NORMAL MODE OPERATION)
Connect the Power Supply Connector into the power supply
jack. The power supply jack is located on the right side
panel towards the lower back corner. Plug the AC power
cord end from the power supply cord into the correct
power source (wall plug): 100-240V~, 50-60Hz.
International use: When traveling internationally, care
should be taken to ensure that you have the correct cord
and wall plug for the country in which the AVACEN 100 is to
be used. Contact AVACEN if the wall plug on the cord does not fit.
If the device has been stored in a hot or cold area, allow it to reach normal room temperature for
1 hour before turning it on.
Turn on the AVACEN device by pressing the button on
the left side of the control panel. The Display will show a
brief welcome message and then will display: "Remove
Jewelry from Hand". This is to prevent damage to the Mitt
and cuff membrane. It will be followed by a "Warming
Heatpad Please Wait…" message. While waiting, remove all
jewelry (rings, bracelets, watches) from the hand and wrist
that will be used for therapy. If you are wearing a shirt or
jacket with long sleeves, pull the sleeve up your arm so that
the inflatable cuff contacts bare skin on your arm. The
inflatable cuff WILL NOT seal against a watch or shirt sleeve.
It is very important that the AVACEN is placed on a level surface and your hand is NOT inside the
Vacuum Chamber when you turn the device on. If your hand is inside the vacuum chamber
(resting on the Heatpad) when the device is turned on, the onboard computer will not measure
your hand pressure correctly. If you turn the device off (by mistake or on purpose), remove your
hand from the Vacuum Chamber before turning the device back on again.
Note: If more than one person will be using the AVACEN, the device can be put into "Standby"
mode so that the Heatpad stays warm in-between uses and the device does not shut down. For
details on this operating mode, refer to the section of this manual below titled "Standby Mode
Operation".
OPTIONAL: While the device is warming up (or at any
other time), the rear feet on the bottom of the AVACEN
unit can be adjusted to ensure the most comfort while
using the device. Turn the feet counter clockwise to
extend the feet; turn clockwise to retract the feet. This
allows the user's elbow to rest on a table or other support
surfaces without extreme bending at the wrist. Sessions
will run from 10 to 30 minutes (user selectable), so it is
recommended to adjust the feet before use.
Remove Jewelry
From Hand
Warming Heatpad
Please Wait...

6 AVACEN 100, User Guide
210116
It will take about 3 minutes for the device to warm up
(depending on the room temperature). Near the end of the
warm-up period, the display will change to "Place Mitt on
Hand".
Place therapy hand in the Mitt. All 4 fingers should be placed
in the body of the mitt and the thumb should be placed in the
right or left thumb cavity of the mitt. Important: Leave 1 cm
(1/2 inch) in top of mitt free when placing hand inside.
After a few seconds, the Ready light will turn from Orange
to Green ("A" on the Control Panel in the figure to the
right).
When the Heatpad has warmed up, the Display Panel will
change to "Insert Hand, Press ✔ and a "beep" will sound.
SLOWLY insert the hand (with Mitt applied) into the Inflatable Cuff. The raised, egg-shaped
portion of the Heatpad should be cupped in the center of the palm. To be most effective, keep all
four fingers resting on the fingertip end of the Metal Heatpad.
Press the ✔ button to indicate that your hand is inserted into the Mitt and Inflatable Cuff, and is
properly positioned on the Metal Heatpad.
IMPORTANT: If you accidentally press the On/Off button instead, remove your hand from the
unit before turning it on again.
Place Mitt
On Hand
Insert Hand
Press ✔
Sanitary
Mitt
should
extend
beyond
Inflatable
Cuff
Metal Heatpad Diagram
Rear Base
(fingertip end)
Front Base
(wrist end)
Position
Heel of Palm
on Front Base

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AVACEN 100 User Guide 7
Set the therapy Time (10 – 30 minutes) on the Control Panel
using the ▲ and ▼ buttons. Set the Temperature (High,
Med, Low) by using the ◄ and ► buttons. OR, do nothing
to accept the default of 15 minutes and High Temperature.
These settings may be changed at any time during use.
Press ✔ on the Control Panel to indicate Time and
Temperature have been set or do nothing to accept default of 15 minutes and High Temperature.
The Time and Temperature settings may be changed at any time during use.
Note: For the most benefit the "High" setting is preferred. Select "Med" or "Low" only in the case
of major discomfort. The Heatpad will feel hot during use. If a lower temperature is used, after
several uses, return to the "High" mode to see if the discomfort has been reduced.
11. CUFF SEALING
The "Sealing Cuff" message is displayed while the vacuum
motor runs. The bar along the bottom shows the vacuum
level; when the bar reaches the length of the Display Panel,
the full vacuum has been achieved.
IMPORTANT NOTE: The seal on the bottom of the Vacuum Chamber may have become
dislodged during shipping and unpacking. If the seal is not properly in place, the Vacuum
Chamber will not seal. Refer to the "Troubleshooting" section of this User Guide for simple ways
to correct this issue.
12. HAND PRESSURE INDICATOR (HPI)
When the unit seals properly, the top line of the display
will show the remaining therapy time and the temperature
level indicator. The bottom line of the display will show
the Hand Pressure Indicator (HPI). The HPI shows if you
have the right amount of hand pressure. You are in the
optimal zone when the double column indicator is near
the middle.
Too much pressure will set off an alarm (beep) and display
"Lift Hand Slightly".
Too little pressure will set off an alarm (beep) and display
"Push Hand Down Slightly". Keeping the HPI in the middle
will ensure ideal function.
Set Time
▲ ▼
Set Temp ◄ ►
Time: 15:00
Temp: High ▇
Sealing Cuff
███████
Time/Temp:14:57
▇
██
Hand Pressure Indicator
Too Little Too Much
Lift Hand
Slightly
Push Hand
Down Slightly
Min Max

8 AVACEN 100, User Guide
210116
13. PAUSING A THERAPY SESSION
PAUSE: If the ✔ button on the control panel is pressed
during treatment, the timer and Vacuum motor are paused.
Pressing ✔ again will cause the timer and Vacuum Chamber
sealing process to resume.
14. ADJUSTING THE THERAPY TIME
Pressing the ▲ button on the control panel while running will cause the therapy timer to
increase in value and holding the ▲ button down will cause the timer to continue increasing until
it reaches the initial set value. Pressing the ▼ button on the control panel while running will
cause the therapy timer to decrease in value. Holding the ▼ button down will cause the timer to
continue dropping until it reaches zero (00:00) Then the AVACEN will shut off.
15. ADJUSTING THE THERAPY TEMPERATURE
Pressing the ◄ or ► buttons during therapy will switch the Temperature setting from High to
Medium to Low, and back to High again.
16. END OF THERAPY
When the treatment time runs down to zero, the device will
begin to shut down. The cuff will begin to deflate and the
"Remove Hand Slowly" message is displayed. Remove your
hand from the Vacuum Chamber. Remove the Mitt and
discard or retain for your own use at a later time. Therapy is
now complete. After a few seconds, the display will change
to "Powering Down", and then the device will turn off.
17. POWERING DOWN
If the button is pressed the device will shut down by
itself. The cuff will begin to deflate and the "Remove Hand
Slowly" message is displayed. Remove your hand from the
Vacuum Chamber. After a few seconds, the display will
change to "Powering Down", and then the device will turn
off.
If there is a problem during operation, the device will
display an error message. If it can not recover, the device
will shut down. After powering down, the display will
continue to show the error message.
Time/Temp:14:57
▇
Paused
Remove Hand
Slowly
Remove Hand
Slowly
Powering
Down
Powering
Down
Unit Did Not
Seal Properly
Calibration
Failed
Unit Has Lost
Vacuum Seal

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AVACEN 100 User Guide 9
18. STANDBY MODE OPERATION
If the AVACEN device is turned ON, turn it off by pressing
the button on the control panel and wait for the green
power light to turn off. If the AVACEN is OFF or has just
been turned OFF, hold down the ✔ button on the control
panel and then press the POWER button. The Display
will show "Entering Standby Mode".
The Display will then show "Remove Jewelry From Hand",
"Warming Heatpad Please Wait…", and after about three
minutes, the "Place Mitt on Hand" and "Insert Hand Press
✔" message will be displayed.
Use is the same as described in the "Normal Mode
Operation" section of this manual.
In the Standby Mode, at the end of a treatment, a "Remove
Hand Slowly" message will be briefly displayed, and then
the "Remaining In Standby Mode" message. In a few
seconds, the startup message and the "Insert Hand"
message will be displayed. The button can be pressed
anytime to turn off Standby Mode and power down the
AVACEN.
The AVACEN is now ready for the next user. The rest of the device functions are the same as
described in the "Normal Mode Operation" section of this manual.
19. GAME MODE OPERATION
To enter Game Mode, you must press the ▲ button when the "Insert Hand / Press ✔" message
is being displayed (after the unit is warmed up). Pressing the ▲ button while warming up has no
effect. This Game Mode setting will persist even if the power is turned off or the unit is powered
down (and also in Standby). Game Mode is reset to OFF when the AVACEN is unplugged. Pressing
the DOWN button when the "Insert Hand / Press ✔" message is being displayed turns Game
Mode OFF.
Game Mode is used to encourage the user to maintain the proper amount of pressure on the
Heatpad. The Hand Pressure Indicator (HPI) position on the bottom row of the Display Panel is
used as the input for the game. The goal is to score the most points by keeping the HPI as close
to the center of the screen as possible.
Entering
Standby Mode
Remove Jewelry
From Hand
Warming Heatpad
Please Wait...
Place Mitt
On Hand
Insert Hand
Press ✔
Remove Hand
Slowly
Remaining In
Standby Mode
Insert Hand
Press ✔
3000 14:57
▇
██
Hand Pressure Indicator (HPI)
Min OPTIMAL Max

10 AVACEN 100, User Guide
210116
An enlarged view of the bottom row of the Display Panel below shows the number of points that
are awarded per second. The number of points earned is based on the position of the HPI. More
points are scored by keeping the HPI in the center of the screen. If the "Lift Hand Slightly"
message or the "Push Hand Down Slightly" message are displayed, the user will hear an audio
beep, and 10,000 points are subtracted from the total score every second.
The highest number of points awarded is 60,000 points per minute. Therefore the user could
accumulate as many as 1,200,000 points in a 20-minute therapy session (more or less points
depending on the length of the session). A score of half the highest possible score (i.e. 600,000
for a 20-minute session) would indicate that the user did a very good job of keeping their hand
properly seated on the heat pad. The final score can also be used as a gauge of proper hand
position during unattended patient therapy sessions. The unit must be used for a minimum of 10
minutes in order to qualify for a high score.
At the end of the session the final score is shown, along with the current high score. If a new high
score was earned, this will be shown. Pressing the ✔ button changes the display to show a
random message. This message falls into one of three basic groups, that vary based on the
average points per second that was scored by the user. If the average points per second is high, a
"Great Job" message will be displayed. If the average points per second was in the middle
(acceptable but not "high"), a "Good Job" message will be displayed. If the average number of
points per second is low, a "Try Harder" message is displayed. These messages can be viewed at
the end of the session (along with the final score) to see how well the user did at keeping their
hand in the correct place on the hand pad during the therapy session.
"Great Job" messages:
"Major league performance! Wow" "Super! That's how it's done!"
"You got some serious skills!" "You did great!"
"Awesome Job!"
"Good Job" messages:
"Nice! beat this score next time!" "Well done, keep up the good work!"
"Next time get the high score!" "Steady hand - good job!"
"You did pretty good!"
"Try Harder" messages:
"I remember MY first time..." "Did you actually try?"
"Come on! Try harder!" "My grandma could do better!"
"Yay! You got the new low score!"
Pressing the ✔ button again causes the unit to turn off or go back into standby mode.
████████████████

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AVACEN 100 User Guide 11
20. TROUBLESHOOTING AND FAQ
If you are having problems using the AVACEN device, review this section to see if a solution is
described. If you are still having trouble, call AVACEN Medical at (888) 4-AVACEN
(888-428-2236) and select "Customer Service" or email: [e-mail]. When
you call, have your AVACEN ready and make note of the device serial number (marked on the
bottom of the device).
A. How long should treatment last?
The AVACEN device is designed to comfortably and noninvasively provide dry heat therapy for a
period between 10 and 30 minutes. For many conditions 15 minutes twice daily is sufficient.
Treatment time and/or use frequency can be increased to accommodate professional
recommendations or absence of response to treatment. The best times for treatment are in the
early morning and prior to bed. Suggested use should be: 15 minutes first thing in the morning
using the LEFT hand (reminder hint: "Left is for day Light") and 15 minutes before bed using the
RIGHT hand (reminder hint: "Right is for Night"). Switching hands assumes both hands are equally
healthy. If not, use the healthy hand only.
Any level of major discomfort (after adjusting temperature) is not normal. Stop using the
AVACEN right away and report the problem to AVACEN at (888) 4-AVACEN (888-428-2236) and
select "Customer Service" or email: [e-mail].
B. How important is the placement of my hand?
It is critical to make sure that the palm is completely inside the vacuum chamber and resting on
the Metal Heatpad. The raised, egg-shaped portion of the Heatpad should be cupped in the
center of the palm.
C. Is it necessary to wear the AVACEN Mitt?
The AVACEN device design requires a special Mitt. Without this mitt, the AVACEN may not seal
properly. Using the mitt also provides a sanitary environment for multiple family members or
clinic users. In addition, the Mitt keeps dirt and hand oils off of the critical metal Heatpad and
from inside the vacuum chamber. This prolongs the efficiency and extends the useful life of the
AVACEN.
D. Do I need a new a Mitt every time I have a treatment?
No. As long as the Mitt appears to be in good repair and clean, the same person may use it for
months.
E. Do I need to purchase the Mitts from AVACEN?
The AVACEN was developed and tested for FDA Clearance using a very specific Mitt material and
design. We have priced the Mitts to be very affordable and therefore recommend that Mitts be
purchased by contacting AVACEN at: customerservic[email protected]

12 AVACEN 100, User Guide
210116
F. The AVACEN unit powers down while the 'Sealing Cuff' message or 'Lost
Vacuum Seal' message is displayed
If the AVACEN is not able to reach the proper vacuum level
after 60 seconds, the "Unit Did Not Seal Properly" message
is displayed and the unit will automatically power down. If
vacuum is lost during a therapy session the "Unit Has Lost
Vacuum Seal" message is displayed and the unit will
automatically power down. This can occur if:
(i) The Inflatable Cuff is not properly sealed at the wrist.
- See Item P: "Checking the inflatable cuff for leaks"
(ii) A Mitt is not being used.
- Put on a Mitt.
(iii) The end of the Mitt does not extend beyond the sealed cuff.
- Pull the mitt on your hand and make sure the end of the mitt is outside the cuff.
(iv) The user's hand is not properly positioned.
-It is critical to make sure that the heel of the palm (where the palm connects to the wrist) is
completely inside the vacuum chamber and touching the palm end of the Metal Heatpad (closest
to opening).
(v) The Vacuum Chamber is not properly positioned.
- See section 23: " PERIODIC MAINTENANCE" for taking the Vacuum Chamber on and off.
If your skin is very dry, put a small amount of hand lotion on your wrist and rub it in to improve
sealing after your hand is placed into the mitt. If you are still having trouble, call AVACEN Medical
at (888) 4-AVACEN (888-428-2236) and select "Customer Service" or email:
[e-mail].
G. "Rest Palm On Heatpad" message
To make sure the device calculates the proper pressure of your hand against the Metal Heatpad,
it is important during the initial sealing and calibration process that you apply slight pressure with
your palm against the Heatpad. Without this base pressure, the onboard computer will not be
able to properly measure the pressure of the palm against the Heatpad and "Rest Palm On
Heatpad" message will continue to appear for 30 seconds and the AVACEN will power down.
It is very important that the AVACEN is placed on a level surface and your hand is NOT inside the
Vacuum Chamber when you turn the unit on. If your hand is inside the vacuum chamber (resting
on the Heatpad) when the unit is turned on, the onboard computer will not measure your hand
pressure correctly. If you turn the unit off (by mistake or on purpose), remove your hand from
the Vacuum Chamber before turning the unit back on again.
Unit Did Not
Seal Properly
Unit Has Lost
Vacuum Seal
Powering
Down

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AVACEN 100 User Guide 13
H. "Calibration Failed" message
It is very important that the AVACEN is placed on a level
surface and your hand is NOT inside the Vacuum Chamber
when you turn the device on. If your hand is inside the
vacuum chamber (resting on the Heatpad) when the device
is turned on, the onboard computer will not measure your
hand pressure correctly. If you turn the device off (by
mistake or on purpose), remove your hand from the
Vacuum Chamber before turning the device back on again.
To make sure that the device computes the proper weight of your hand against the Metal
Heatpad it is important during the initial sealing and calibration process to apply slight pressure
with your palm against the Heatpad. Without this base pressure, the onboard computer will not
be able to properly manage the pressure of the palm against the Heatpad. At that point the
"Calibration Failed" message will appear and the device will shut down.
After the weight of the hand is measured during the calibration phase, the onboard computer
monitors if there is too much or too little palm pressure against the Heatpad. This will be
displayed on the Hand Pressure Indicator (HPI). After a number of uses, it will become much
easier to judge the proper pressure of your palm against the Heatpad. If you are still having
trouble, call AVACEN at (888) 4-AVACEN (888-428-2236) and select "Customer Service" or email:
[e-mail].
I. "System Error" Message
The device is always checking and adjusting the
temperature of the Heatpad. If for some reason it can not
measure the Heatpad temperature, a warning message will
be displayed. This can happen for a few reasons:
(i) The device is very cold.
- Turn off the device and allow it to warm to room temperature before turning on.
(ii) The device has been stored somewhere very hot.
- This may have damaged the device. Unplug the unit, then plug back in and try again. If the
message is displayed a second time, call AVACEN at (888) 4-AVACEN (888-428-2236) and select
"Customer Service" or email: CustomerSe[email protected]om.
J. There is noise while the AVACEN device is running
There is an air pump inside the AVACEN that runs during therapy. Some motor noise is normal,
and the noise will vary as the AVACEN adjusts the air pressure of the inflatable cuff and inside the
vacuum chamber. This improves the comfort of the inflatable cuff.
K. The inflatable cuff is too tight
The inflatable wrist bladder is designed to work on almost any size wrist and therefore it may feel
tighter to some people than others. The first inflation exerts the most pressure to assure a proper
seal every time. This highest pressure will only last for less than a minute. After that the pressure
will relax to a more comfortable level. If the pressure does not relax there may be a vacuum leak.
Refer to Item F: "The AVACEN unit powers down while the 'Sealing Cuff' message or 'Lost Vacuum
Seal' message is displayed" for solutions.
Calibration
Failed
Powering
Down
System Error
Unplug Unit

14 AVACEN 100, User Guide
210116
L. I keep getting a "Push Hand Down Slightly" or "Lift Hand Slightly"
message
It is very important that the AVACEN is placed on a level surface and your hand is NOT inside the
Vacuum Chamber when you turn the device on. If your hand is inside the vacuum chamber
(resting on the Heatpad) when the device is turned on, the onboard computer will not measure
your hand pressure correctly. If you turn the device off (by mistake or on purpose), remove your
hand from the Vacuum Chamber before turning the device back on again.
To make sure that the device calculates the proper pressure of your hand against the Heatpad it
is important that during the initial sealing and calibration process that you apply slight pressure
with your palm against the Heatpad. Without this base pressure, the onboard computer will not
be able to properly manage the pressure of the palm against the Heatpad and "Push Hand Down
Slightly" or "Lift Hand Slightly" message will continue to appear along with a beeping sound.
During treatment there is a chance the heel of your palm will be pushing too hard against the
palm end of the Metal Heatpad (end nearest the wrist opening). This condition is not wanted and
will cause the "Lift Hand Slightly" message to appear along with a beeping sound. At this point
just retract your hand into the cuff to its original position and the alerts will stop.
One of the top features of the device is to monitor and display too much or too little pressure of
the hand on the Metal Heatpad. Correct hand pressure on the Heatpad increases heat transfer.
After the weight of the hand is calculated during the calibration phase, the onboard computer is
responsible for monitoring the palm pressure. If there is too much or too little palm pressure
against the Heatpad, it will be displayed on the Hand Pressure Indicator (HPI). After a number of
uses, it will become much easier to judge the proper pressure of your palm against the Heatpad.
If you are still having trouble, call AVACEN at (888) 4-AVACEN (888-428-2236) and select
"Customer Service" or email: CustomerSe[email protected]om.
M. The AVACEN Heatpad is too hot (or too cool)
For the most benefit "High" is recommended. Select "Med" or "Low" only in the case of major
discomfort. The Heatpad will feel hot during use. If a lower temperature is used, return to the
"High" mode after several uses to determine if the discomfort has been reduced. If the heat does
not recede to a more comfortable level RIGHT AWAY stop using the device and call AVACEN
Medical at (888) 4-AVACEN (888-428-2236) and select "Customer Service" or email:
[e-mail] After using the device for some time, you hand may get used to
the heatpad temperature, so that it does not "feel" as hot as it used to. This is normal and does
not mean there is a problem with the device.
N. The Heatpad seems "loose"
For proper measurement of hand weight on the heatpad, the heatpad must be free to move up
and down and side-to-side slightly. This is normal and does not mean there is a problem.

210116
AVACEN 100 User Guide 15
O. The Display Panel Power LED does not illuminate after pushing the ON
Button
Make sure that the power cord is plugged into the unit and the light on the Power Supply (black
box between the device plug and wall plug) is on. If the light on the Power Supply is not on;
check the ends of the power cord to make sure it is plugged into both the Power Supply and the
wall plug. If the power Supply light is still not on, make sure that the wall plug is working
properly. Do this by plugging in another device or lamp that you know works into the wall plug. If
you are still having trouble, call AVACEN Medical at (888) 4-AVACEN (888-428-2236) and select
"Customer Service" or email: CustomerSe[email protected]om.
P. Checking the inflatable cuff for leaks
This test can be found in USER SETTINGS. Refer to section 21: "USER SETTINGS" in this Guide for
details on starting the test.
Q. Excessive swelling of the hand
The AVACEN device is designed to comfortably and noninvasively provide dry heat therapy. Any
level of major discomfort is not normal. Right away stop using the AVACEN and report the
problem to AVACEN Medical at (888) 4-AVACEN (888-428-2236) and select Customer Service.
R. Red or purple spots on the hand
Red or purple spots on the hand (usually the backside) after the first couple of AVACEN device
uses can be caused by a minor hemorrhage (petechia). These spots are harmless and will likely
vanish within a few days. Should they not disappear or if they are accompanied by any level of
major discomfort; this is not normal. Right away stop using the AVACEN and report the
problem to AVACEN Medical at (888) 4-AVACEN (888-428-2236) and select Customer Service.
S. Hand itches or tingles
It is common and normal for the hand to slightly itch or tingle during a treatment session as
circulation in the hand increases. If this at any time becomes uncomfortable or painful,
immediately stop the treatment session and call AVACEN Medical at (888) 4-AVACEN (888-428-
2236) and select Customer Service.
T. My hand is reddish-colored like it has been in hot water
This state is normal and you will likely see this on every treatment. It is due to the increased
microcirculation (blood in the capillaries).
U. Sweating when using the AVACEN
The AVACEN device is designed to comfortably and noninvasively provide heat therapy. Mild
sweating is not typical but seldom may occur and is not a serious indication. Any level of major
discomfort pain is not normal. Right away stop using the AVACEN and report the problem to
AVACEN Medical at (888) 4-AVACEN (888-428-2236).
V. Discomfort in wrist or forearm during use
Raise or lower forearm or adjust rear device feet to increase comfort.

16 AVACEN 100, User Guide
210116
21. USER SETTINGS
There are some settings that can be made on the AVACEN unit that will be stored. Even if power
is removed, the settings are kept. The following User Settings can be made on the AVACEN:
 Language Selection
 Beep Tone Style
 Default Therapy Time
 Default Therapy Temperature
In addition, there are some settings that can be used to help diagnose problems with the device:
 Display Error Messages
 Measure Hand Pad Force
 Run Self-Sealing Test
All of these features are accessed in the User Settings menu. To access User Settings, begin by
turning the AVACEN device Off. Press and hold down the ▼ button while turning the device On
with the button. The display will show "User Settings".
Moving through the different User Settings is done using the front panel buttons:
◄ or ► Press to scroll back or forward through menu selections.
▲ or▼ Press to scroll up or down through menus and options.
✔ To store the selected setting.
◄ Go back to the previous (higher level) menu.
After you are done making changes to any of the settings, press ◄ one or more times until the
display shows "User Settings". Then press the button to return to normal operation.
While in the "User Settings" menu, press ►, then press ▲ or▼ one or more times to go to the
following menus:
A. Language Selection
Messages can be displayed in multiple languages on some
device versions. Press ► to enter this menu, then press ▲
or▼ to choose the desired language. Press ✔ to select the
desired language. If this menu is not available, then your
device only supports English.
B. Beep Tone Style
There are two options, "Original" and "Low Tones". Press
► to enter this menu, then press ▲ or▼ to choose a style
of Beep Tone. A sample of the tones will sound. Press ✔
to select the desired Beep Tones.
C. Default Therapy Session Time
The default setting for therapy time is 15 minutes. At any
time before the start of a therapy session, the therapy
time may be changed from 15 minutes to 10, 20, 25, or 30
minutes. If you find that you a usually selecting a time
other than 15 minutes for therapy, the default therapy
User Settings:
Change Display
Language
Beep Tone
Select
Default Session
Time/Temp
Set Default
Session Time