Bruker InsightMR User manual

InsightMR
User Manual
Version 003
Innovation with Integrity
●
NMR

Copyright © by Bruker Corporation
All rights reserved. No part of this publication may be reproduced, stored in a retrieval
system, or transmitted, in any form, or by any means without the prior consent of the
publisher. Product names used are trademarks or registered trademarks of their re-
spective holders.
This manual was written by
InsightMR team
© February 07, 2017 Bruker Corporation
Document Number: 10000054012
P/N: H155936
For further technical assistance for this product, please do not hesitate to contact your
nearest BRUKER dealer or contact us directly at:
Bruker Corporation
Am Silberstreifen
76287 Rheinstetten
Germany
Phone: + 49 721 5161 6155
E-mail: [email protected]
Internet: www.bruker.com

Contents
H155936_3_003 iii
Contents
1 About This Manual .............................................................................................................................5
1.1 Policy Statement .................................................................................................................5
1.2 Symbols and Conventions ..................................................................................................5
2 Introduction.........................................................................................................................................7
2.1 Concept...............................................................................................................................7
2.2 Intended Use.......................................................................................................................7
2.3 Limitation of Liability............................................................................................................8
2.4 Copyright.............................................................................................................................8
2.5 Warranty Terms ..................................................................................................................8
2.6 Customer Service ...............................................................................................................8
3 Safety...................................................................................................................................................9
3.1 System Owner's Responsibility...........................................................................................9
3.2 Personnel Requirements ..................................................................................................10
3.2.1 Unauthorized Persons ......................................................................................................11
3.2.2 Instruction .........................................................................................................................11
3.3 Personal Protective Equipment.........................................................................................11
3.4 General Workplace Dangers.............................................................................................12
4 Design and Function ........................................................................................................................15
4.1 Description ........................................................................................................................15
4.2 Software............................................................................................................................17
5 Transport, Packaging and Storage .................................................................................................19
5.1 Symbols on the Packaging ...............................................................................................19
5.2 Inspection at Delivery........................................................................................................20
5.3 Packaging .........................................................................................................................20
5.4 Storage .............................................................................................................................21
6 Flow Unit Installation .......................................................................................................................23
6.1 Choose the Position of the Reactor ..................................................................................23
6.2 Connecting the Transfer Line Holder ................................................................................24
6.3 Testing the Flow Unit Prior to Inserting it into the Magnet ................................................24
6.4 Temperature Control (optional).........................................................................................26
6.5 Software Installation..........................................................................................................27
6.6 Software Configuration .....................................................................................................32
6.6.1 TopSpin Configuration ......................................................................................................32
6.6.2 InsightMR Flow Mode Configuration.................................................................................32
6.6.2.1 Recommended Settings....................................................................................................34
6.6.3 Adding a New Protonated Solvent ....................................................................................38
7 Operation...........................................................................................................................................39
7.1 Inserting and Using the Flow Unit .....................................................................................39
7.2 Acquiring NMR Data Using InsightMR Software...............................................................40
7.3 Removing the Flow Unit for Storage in the Transport Box................................................41
7.4 Returning the Spectrometer to Normal Operation ............................................................41

Contents
iv H155936_3_003
8 Flow Tube Assembly - Insertion Checklist ....................................................................................43
8.1 Prepare the NMR System .................................................................................................43
8.2 Prepare the Flow Tube Assembly.....................................................................................44
8.3 Connect the Temperature Control Equipment (Optional) .................................................44
8.4 Connect the Sample Supply (Reactor or Equivalent) .......................................................44
8.5 Insert the Flow Tube Assembly.........................................................................................45
8.6 The System is Ready to be Used .....................................................................................45
9 Flow Tube Assembly - Removal Checklist.....................................................................................47
9.1 Prepare the Flow Tube Assembly.....................................................................................47
9.2 Remove the Flow Tube Assembly ....................................................................................47
9.3 Storage .............................................................................................................................48
9.4 Prepare the NMR System .................................................................................................48
9.5 The system is ready for normal usage..............................................................................48
10 InsightMR Glass Flow Tube Exchange Instructions .....................................................................49
10.1 Removing the Glass Flow Tube........................................................................................49
10.2 Mounting the Glass Flow Tube .........................................................................................50
11 Dismantling and Disposal................................................................................................................51
11.1 Dismantling .......................................................................................................................51
11.2 Disposal Europe................................................................................................................51
11.3 Disposal USA and Other Countries ..................................................................................52
12 Technical Data ..................................................................................................................................53
13 Contact ..............................................................................................................................................55
List of Figures...................................................................................................................................57

About This Manual
H155936_3_003 5
1 About This Manual
This manual enables safe and efficient handling of the device.
This manual is an integral part of the device, and must be kept in close proximity to the
device where it is permanently accessible to personnel. In addition, instructions concerning
labor protection laws, operator regulations tools and supplies must be available and adhered
to.
Before starting any work, personnel must read the manual thoroughly and understand
its contents. Compliance with all specified safety and operating instructions, as well as local
work safety regulations, are vital to ensure safe operation.
The figures shown in this manual are designed to be general and informative and may not
represent the specific Bruker model, component or software/firmware version you are
working with. Options and accessories may or may not be illustrated in each figure.
1.1 Policy Statement
It is Bruker’s policy to improve products as new techniques and components become
available. Bruker reserves the right to change specifications at any time.
Every effort has been made to avoid errors in text and Figure presentation in this publication.
In order to produce useful and appropriate documentation, we welcome your comments on
this publication. Field Service Engineers are advised to check regularly with Bruker for
updated information.
Bruker is committed to providing customers with inventive, high-quality, environmentally-
sound products and services.
1.2 Symbols and Conventions
Safety instructions in this manual and labels of devices are marked with symbols. .
The safety instructions are introduced using indicative words which express the extent of the
hazard.
In order to avoid accidents, personal injury or damage to property, always observe safety
instructions and proceed with care.
DANGER
DANGER indicates a hazardous situation which, if not avoided, will result in
death or serious injury.
This is the consequence of not following the warning.
1. This is the safety condition.
uThis is the safety instruction.

About This Manual
6 H155936_3_003
WARNING
WARNING indicates a hazardous situation, which, if not avoided, could result
in death or serious injury.
This is the consequence of not following the warning.
1. This is the safety condition.
uThis is the safety instruction.
CAUTION
CAUTION indicates a hazardous situation, which, if not avoided, may result in
minor or moderate injury or severe material or property damage.
This is the consequence of not following the warning.
1. This is the safety condition.
uThis is the safety instruction.
NOTICE
NOTICE indicates a property damage message.
This is the consequence of not following the notice.
1. This is a safety condition.
uThis is a safety instruction.
SAFETY INSTRUCTIONS
SAFETY INSTRUCTIONS are used for control flow and shutdowns in the event
of an error or emergency.
This is the consequence of not following the safety instructions.
1. This is a safety condition.
uThis is a safety instruction.
This symbol highlights useful tips and recommendations as well as
information designed to ensure efficient and smooth operation.

Introduction
H155936_3_003 7
2 Introduction
Designed for the analysis of chemical processes by NMR, InsightMR is the ideal solution for
both industrial and academic scientists studying or optimizing reactions. InsightMR’s two
components, a flow unit and dedicated software, enable online monitoring of chemical
reactions in real-time under real process conditions.
2.1 Concept
The flow unit enables online monitoring of chemical reaction in real-time under real
conditions. This is achieved by fast and continuous transfer of reactions mixtures from a
reaction vessel into a glass flow tube, located in the NMR probe, with temperature control
from the flow interface to the probe. Designed to work with 5 mm probes, the flow unit is a
versatile proposition to flow chemistry by NMR.
The dedicated InsightMR software is a platform designed for the analysis of chemical
processes by NMR. Integrated acquisition control and data processing features enable on-
the-fly acquisition parameter adjustment based on real-time kinetic data.
2.2 Intended Use
The InsightMR glass flow tube is an insert for standard 5 mm NMR probes. It allows the
transfer of liquid from an external container through a transfer line into the NMR detection
area and back. Once the liquid is in the detection area, NMR data can be acquired either
under static or continuously flowing conditions. A schematic of the intended setup is shown in
the figure Figure 4.2 [}16].
Typically the InsightMR flow unit is used to continuously circulate the liquid from a reaction
vessel through the NMR probe. By this procedure the changing composition of the liquid in
the vessel, i.e. the progress of the reaction, can be continuously monitored. The low volumes
of the system ensure that after a short time the composition in the NMR glass flow tube
corresponds to the composition in the reactor.
The InsightMR modular design allows the user to maintain the system easily. In the case of
contamination from compounds that cannot be removed with simple flushing, the glass flow
tube can be removed and cleaned or replaced. The glass flow tube, and various other
components are highlighted in the figure Figure 4.1 [}15].
The system can be used for other purposes where a flow with changing composition should
be monitored. However the usage as an HPLC-NMR system is not recommended since it is
designed to allow fast transfer with high flow rates, which would cause peak broadening in an
HPLC chromatogram.

Introduction
8 H155936_3_003
2.3 Limitation of Liability
All specifications and instructions in this manual have been compiled taking account of
applicable standards and regulations, the current state of technology and the experience and
insights we have gained over the years.
The manufacturer accepts no liability for damage due to:
• Failure to observe this manual.
• Improper use.
• Deployment of untrained personnel.
• Unauthorized modifications.
• Technical modifications.
• Use of unauthorized spare parts.
The actual scope of supply may differ from the explanations and depictions in this manual in
the case of special designs, take-up of additional ordering options, or as a result of the latest
technical modifications.
The undertakings agreed in the supply contract, as well as the manufacturer's Terms and
Conditions and Terms of Delivery, and the legal regulations applicable at the time of the
conclusion of the contract shall apply.
2.4 Copyright
All rights reserved. This manual is protected by copyright and intended solely for internal use
by customers.
This manual must not be made available to third parties, duplicated in any manner or form –
whether in whole or in part – and the content must not be used and/or communicated, except
for internal purposes, without the written consent of the manufacturer.
Product names used are trademarksTM or registered trademarks® of their respective holders.
Violation of the copyright will result in legal action for damages. We reserve the right to assert
further claims.
2.5 Warranty Terms
The warranty terms are included in the manufacturer's Terms and Conditions.
2.6 Customer Service
Our customer service division is available to provide technical information. See the chapter
Contact for contact information.
In addition, our employees are always interested in acquiring new information and experience
gained from practical application; such information and experience may help improve our
products.

Safety
H155936_3_003 9
3 Safety
3.1 System Owner's Responsibility
System Owner
The term system owner refers to the person who operates the device for trade or commercial
purposes, or who surrenders the device to a third party for use/application, and who bears
the legal product liability for protecting the user, the personnel or third parties during the
operation.
System Owner‘s Obligations
The device is used in the industrial sector, universities and research laboratories. The system
owner of the device must therefore comply with statutory occupational safety requirements.
In addition to the safety instructions in this manual, the safety, accident prevention and
environmental protection regulations governing the operating area of the device must be
observed.
In this regard, the following requirements should be particularly observed:
• The system owner must obtain information about the applicable occupational safety
regulations, and - in the context of a risk assessment - must determine any additional
dangers resulting from the specific working conditions at the usage location of the device.
The system owner must then implement this information in a set of operating instructions
governing operation of the device.
• During the complete operating time of the device, the system owner must assess whether
the operating instructions issued comply with the current status of regulations, and must
update the operating instructions if necessary.
• The system owner must clearly lay down and specify responsibilities with respect to
installation, operation, troubleshooting, maintenance and cleaning.
• The system owner must ensure that all personnel dealing with the device have read and
understood this manual. In addition, the system owner must provide personnel with
training and hazards information at regular intervals.
• The system owner must provide the personnel with the necessary protective equipment.
• The system owner must warrant that the device is operated by trained and authorized
personnel as well as all other work, such as transportation, mounting, start-up, the
installation, maintenance, cleaning, service, repair and shutdown, that is carried out on the
device.
• All personnel who work with, or in the close proximity of the device, need to be informed of
all safety issues and emergency procedures as outlined in this user manual.
• The system owner must document the information about all safety issues and emergency
procedures in a laboratory SOP (Standard Operating Procedure). Routine briefings and
briefings for new personnel must take place.
• The system owner must ensure that new personnel are supervised by experienced
personnel. It is highly recommended to implement a company training program for new
personnel on all aspects of product safety and operation.
• The system owner must ensure that personnel are regularly informed of the potential
hazards within the laboratory. This is all personnel that work in the area, but in particular
laboratory personnel and external personnel such as cleaning and service personnel.

Safety
10 H155936_3_003
• The system owner is responsible for taking measures to avoid inherent risks in the
handling of dangerous substances, preventing industrial disease, and providing medical
first aid in emergencies.
• The system owner is responsible for providing facilities according to the local regulations
for the prevention of industrial accidents and generally accepted safety regulations
according to the rules of occupational medicine.
• All substances needed for operating and cleaning the device samples, solvents, cleaning
agents, gases, etc. have to be handled with care and disposed of appropriately. All hints
and warnings on storage containers must be read and adhered to.
• The system owner must ensure that the work area is sufficiently illuminated to avoid
reading errors and faulty operation.
• The system owner must ensure that the laboratory is equipped with an oxygen warning
device, in case the device is operated with nitrogen.
Furthermore, the system owner is responsible for ensuring that the device is always in a
technically faultless condition. Therefore, the following applies:
• The system owner must ensure that the maintenance intervals described in this manual
are observed.
• The system owner must ensure that all (electrical, mechanical, etc.) safety devices are
regularly checked to ensure full safety functionality and completeness.
3.2 Personnel Requirements
This manual specifies the personnel qualifications required for the different areas of work,
listed below.
Laboratory Personnel
Laboratory personnel are professionals, technicians, and assistants staffing a research
facility where specimens are grown, tested, or evaluated and the results of such measures
are recorded. Laboratory personnel are able to carry out assigned work and to recognize and
prevent possible dangers self-reliant due to their professional training, knowledge and
experience as well as profound knowledge of applicable regulations.
The workforce must only consist of persons who can be expected to carry out their work
reliably. Persons with impaired reactions due to, for example, the consumption of drugs,
alcohol, or medication are prohibited from carrying out work on the device.
When selecting personnel, the age-related and occupation-related regulations governing the
usage location must be observed.

Safety
H155936_3_003 11
3.2.1 Unauthorized Persons
WARNING
Risk to life for unauthorized personnel due to hazards in the danger and
working zone!
Unauthorized personnel who do not meet the requirements described in this manual will not
be familiar with the dangers in the working zone. Therefore, unauthorized persons face the
risk of serious injury or death.
uUnauthorized persons must be kept away from the danger and working zone.
uIf in doubt, address the persons in question and ask them to leave the danger and
working zone.
uCease work while unauthorized persons are in the danger and working zone.
3.2.2 Instruction
Personnel must receive regular instruction from the owner. The instruction must be
documented to facilitate improved verification.
Date Name Type of
Instruction
Instruction
Provided By
Signature
3.3 Personal Protective Equipment
Personal protective equipment is used to protect the personnel from dangers which could
affect their safety or health while working.
Personnel must wear personal protective equipment while carrying out the different
operations at and with the device.
This equipment will be defined by the head of the laboratory. Always comply with the
instructions governing personal protective equipment posted in the work area.

Safety
12 H155936_3_003
3.4 General Workplace Dangers
Please refer to the figure Figure 4.1 [}15] for the location of parts mentioned in this section.
CAUTION
Risk of contamination from toxic liquids or vapors during operation.
Contamination may occur from sample liquid leaking into the laboratory environment.
uClean any chemical leakages or spills immediately following all appropriate safety
precautions for safe chemical handling and laboratory cleaning procedures.
uWear proper personal protective equipment. Examples include but are not limited to
gloves, goggles, lab coat, etc.
uThe volume of sample liquid in the reactor must not exceed 2.5 liters.
uUtilize a fume hood over the reactor, fluid pump, and the sample and temperature
control connectors to the reaction transfer line.
uPlace a container that can hold up to 10 liters of liquid, and is appropriately rated for
chemical spills, below the probe.
uOnly reactions with moderately hazardous products should be carried out. The cleaning
of accidental spillage of sample liquid must be possible using standard safety equipment
(goggles, lab coat, gloves, etc.).
CAUTION
Risk of injury from broken glass during glass flow tube replacement.
Incorrect handling of the glass flow tube during installation may result in broken glass and
possible injury.
uWear proper personal protective equipment. Examples include, but are not limited to,
gloves, goggles, lab coat, etc.
uAlways use the flow tube protector to exchange the glass flow tube (see Mounting the
Glass Flow Tube [}50]).
CAUTION
Risk of contamination from toxic liquids or vapors during service and
installation.
Insufficient cleaning/flushing of the flow unit prior to storage may result in a risk of
contamination from toxic liquids or vapors during service and installation.
uWear proper personal protective equipment. Examples include, but are not limited to,
gloves, goggles, lab coat, etc.
uClean and flush the sample line after usage with a suitable solvent that is compatible
with the solubility of all components used in the experiment.
uSeal the inlet and outlet of the sample line and temperature control lines while the
system is outside the magnet and prior to storage.
uUse an inert, non-toxic temperature control liquid like glycol.

Safety
H155936_3_003 13
NOTICE
Material damage to the NMR probe from sample liquid after a glass flow tube
breakage.
Sample liquid leaking into the NMR probe as a result of breakage of the glass flow tube may
result in material damage to the NMR probe.
uDo not apply pressure above 10 bar to the flow unit assembly.
uBefore introducing the flow unit assembly in the magnet, check for leakages in the unit
at the flow rate and temperature value s that will be later used during the experiment.
uHandle the flow unit assembly with care when inserting it into the magnet.
uUse a sample delivery pump with a maximum operating pressure below the specified
pressure limit of the flow unit assembly or set the pressure limit of the pump not to
exceed the specified pressure limit.
uThe maximum allowed flow rate for the flow unit and reaction sample line is 5 mL/min =
0.3 L/h.
NOTICE
Material damage to the NMR probe from sample liquid leaking from flow unit.
Sample liquid leaking into the NMR probe as a result of flow unit leakage may result in
material damage to the NMR probe.
uDo not apply pressure above 10 bar to the flow unit assembly.
uBefore introducing the flow tube assembly in the magnet, check for leakages in the unit
at the flow rate and temperature values that will be later used during the experiment.
uExchange the glass flow tube sealing O-rings regularly. If using solvents that are known
to be destructive to polymers (Kalrez) exchange the O-rings after each use.
uDo not exceed the maximum flow rate for the flow unit and reaction sample line of 5 mL/
min = 0.3 L/h.
NOTICE
Material damage to the magnet from sample liquid after a glass flow tube
breakage or from flow unit leakage.
Sample liquid leaking into the bore of the magnet as a result of a glass flow tube breakage or
from flow unit leakage may cause material damage to the magnet.
uThe volume of sample liquid in the reactor should not exceed 2.5 liters.
uExchange the glass flow tube sealing O-rings regularly. If using solvents that are known
to be destructive to polymers (Kalrez) exchange the O-rings after each use.
uDo not exceed the maximum flow rate for the glass flow tube and sample line of 5 mL/
min = 0.3 L/h.

Safety
14 H155936_3_003
NOTICE
Material damage to the NMR probe or magnet from temperature control liquid.
Leakage of temperature control liquid from reaction control connectors into the NMR probe
or magnet may result in material damage.
uUse a temperature control unit with a maximum operating pressure set to <= 0.5 bar.
uDo not apply pressure greater than 1 bar to the reaction temperature line.
uBefore introducing the flow unit assembly in the magnet, check for leakages in the unit
at the flow rate and temperature values that will be later used during the experiment.
uUse an inert, non-toxic temperature control liquid like glycol.
uThe volume of the temperature control liquid must not exceed 5 liters.
CAUTION
Risk of contamination from toxic liquids or vapors after a glass flow tube
breakage or from flow unit leakage.
Contamination from toxic liquids or vapors may result after a glass flow tube breakage or
from leakage of sealing O-rings or connectors.
uWear proper personal protective equipment. Examples include but are not limited to
gloves, goggles, lab coat, etc.
uFor test purposes, use only non-toxic harmless compounds, for example sucrose in
H2O/D2O.
uClean and decontaminate the entire flow unit assembly prior to service tasks and
confirm the decontamination.
NOTICE
Material damage to the reactor due to movement of the flow unit assembly.
Movement of the flow unit assembly during insertion/removal of the flow unit and InsightMR
transfer line into or from the magnet may cause damage to the reactor. Accidental
movement of the reaction transfer line by persons accessing the system may also cause
material damage.
uSecure the end of the InsightMR transfer line close to the reactor to prevent movement
(e.g. push/pull or rotation).
uPrevent access to the space between the reactor and magnet where the InsightMR
transfer line is installed.

Design and Function
H155936_3_003 15
4 Design and Function
4.1 Description
InsightMR hardware consists of an insulated transfer line with an NMR glass flow tube on one
end and a flow interface with an isolation valve on the other end:
1
2
34
5
6
Figure4.1: InsightMR Flow Tube Assembly and the Transfer Line
1 Sample Lines 4 Glass Flow Tube
2 Temperature Control Lines 5 Tube Holder
3 The Transfer Line. Consists of the
temperature control lines, sample lines
and insulation. Available in standard
lengths of 4 and 7 meter, or in custom
lengths of 5, 6 and 9 meters.
6 Holder Body

Design and Function
16 H155936_3_003
In addition, a sample line holder (shown in the following figure, on top of the magnet), a spare
parts kit and documentation are provided. Refer to Connecting the Transfer Line Holder
[}24] for instructions on how to install it.
Figure4.2: Recommended Laboratory Setup
The glass flow tube with flow tube protector and flow interface are shown in the figure Figure
4.3 [}17].
The 5 mm NMR glass flow tube together with the tube holder, which has the shape of a
spinner, is compatible with any standard Bruker 5 mm NMR probe with insertion depth of 20
mm. The InsightMR glass flow tube volume corresponds approximately to the active volume
of a standard 5 mm tube.
The transfer line is composed of 2 sample lines, sample in and sample return, and 2
concentric temperature control lines surrounding the sample lines. Thermostatic liquid is
flushed through the temperature control lines to maintain the temperature during the sample
transfer to the NMR and back. Insulating foam around the transfer line prevent temperature
loss, condensation and injury through high temperatures.
The recommended laboratory set up is shown in the figure Figure 4.2 [}16]. The pump and
the thermostat can be purchased together with InsightMR, as options. They are not included
as default.
The reaction mixture is pumped from the vessel, through the pump, the valve (flow interface)
and the sample lines, to the NMR and back. Tubing and standard HPLC fittings are provided
to connect the vessel to the pump, the pump to the valve and the valve back to the reactor.
The temperature control line inlets and outlets are fixed to the flow interface, which can be
secured to a laboratory stand.

Design and Function
H155936_3_003 17
1
2
3
4
5
Figure4.3: InsightMR Flow Tube Assembly, Flow Tube Protector and Flow Interface
1 Flow Interface 4 Sample Valve Outlet
2 Flow Control Valve 5 Flow Tube Protector
3 Sample Valve Inlet
4.2 Software
InsightMR includes the flow unit and dedicated software. Use of this software is highly
recommended. The software integrates acquisition control and data processing features,
enabling on-the-fly acquisition parameter adjustment based on real-time kinetic data.
Please refer to the section Software Installation [} 27] for instructions on the software
installation.
Upon installation and launch, a quick start guide is available under Help - QuickStart.
NOTICE
Material damage to flow unit due to incorrect automation mode
Failure to set the Sample Changer/Automation mode to Flow Tube (InsightMR) may result
in flow tube breakage.
uSet the Sample Changer/Automation to Flow Tube (InsightMR) in IconNMR
configuration Automation/Master Switches.

Design and Function
18 H155936_3_003

Transport, Packaging and Storage
H155936_3_003 19
5 Transport, Packaging and
Storage
Retrofitting, repairs, adjustments or dismantling of the device must only be carried out by
Bruker Service or personnel authorized by Bruker. Damage due to servicing that is not
authorized by Bruker is not covered by your warranty.
5.1 Symbols on the Packaging
The following symbols are affixed to the packaging material. Always observe the symbols
during transport and handling.
Top The arrow tips on the sign mark the top of the
package. They must always point upwards;
otherwise the content may be damaged.
Fragile Marks packages with fragile or sensitive
contents.
Handle the package with care; do not allow the
package to fall and do not allow it to be
impacted.
Protect Against Moisture Protect packages against moisture and keep
dry.
Attach Here Lifting gear (lifting chain, lifting strap) must
only be attached to points bearing this symbol.
Center of Gravity Marks the center of gravity of packages.
Note the location of the center of gravity when
lifting and transporting.
Weight, Attached Load Indicates the weight of packages.
Handle the marked package in accordance
with its weight.
Permitted Stacking Load Indicates packages which are partially
stackable.
Do not exceed the maximum load-bearing
capacity specified on the symbol in order to
avoid damaging or destroying the content.

Transport, Packaging and Storage
20 H155936_3_003
Do not Damage Air-tight
Packaging
The packaging is air-tight. Damage to the
barrier layer may render the contents
unusable.
Do not pierce.
Do not use sharp objects to open.
Component Sensitive to
Electrostatic Discharge
The packaging contains components which
are sensitive to an electrostatic discharge.
Only allow packaging to be opened by trained
personnel.
Establish potential equalization before
opening.
Protect from Heat Protect packages against heat and direct
sunlight.
Protect from Radioactive
Sources
Protect packages against radioactive sources.
Table5.1: Symbols on the Packaging
5.2 Inspection at Delivery
Upon receipt, immediately inspect the delivery for completeness and transport damage.
Proceed as follows in the event of externally apparent transport damage:
• Do not accept the delivery, or only accept it subject to reservation.
• Note the extent of the damage on the transport documentation or the shipper's delivery
note.
• Initiate complaint procedures.
Issue a complaint in respect to each defect immediately following detection. Damage
compensation claims can only be asserted within the applicable complaint deadlines.
5.3 Packaging
About Packaging
The individual packages are packaged in accordance with anticipated transport conditions.
Only environmentally friendly materials have been used in the packaging.
The packaging is intended to protect the individual components from transport damage,
corrosion and other damage prior to assembly. Therefore do not destroy the packaging and
only remove it shortly before assembly.
Handling Packaging Materials
Keep the original container and packing assembly, at least as long the warranty is valid, in
case the unit has to be returned to the factory. When the packaging material is no longer
needed dispose of in accordance with the relevant applicable legal requirements and local
regulations.