ChemoMetec NucleoCounter NC-250 User manual

Doc. No.: 994-0029 v. 2.0 · Issue date: 26-Aug-2021
Page 1 of 2
ChemoMetec A/S · Gydevang 43 · 3450 Allerod · Denmark · [e-mail] · www.chemometec.com
Technical Note No. 994-0029 Rev. 2.0
Cleaning Guide: NucleoCounter® NC-250™ and NC-3000™
We recommend regular cleaning of the NucleoCounter® NC-250™ and NC-3000™ instruments to protect
their surfaces and to ensure data image quality.
Cleaning the Exterior
When cleaning the exterior of the NucleoCounter® NC-250™ and NC-3000™ instrument, use a soft damp
cloth and gently wipe the surface. If contamination does not come off immediately, rub gently with a cloth
moistened with mild detergent. Never use organic solvents or aggressive detergents to clean the exterior of
the NucleoCounter®.
Cleaning the Sample Tray
When cleaning the sample tray, take great care not to introduce any liquid or dust. Any liquid that enters
the interior of the NucleoCounter® can damage the optical parts, compromising the quality of the cell
count. The black surface of the sample tray is made of anodized aluminum and can therefore be wiped off
with a clean, dry and dust-free cloth to avoid introducing fibers to the sample tray.
Always keep the sample tray inserted when the instrument is not in use to protect the optical parts inside
the NucleoCounter® against dust and other contaminants.
Removing Dust Particles
The presence of an object or a particle
(e.g. dust) will not normally influence
counts made by the NucleoCounter®.
The instrument will distinguish between
cells and non-cells, since cells are
generally significantly smaller.
However, the presence of objects on the
surface of an optical component can
affect the visual data display (see Figure
1).
Figure 1. Contaminated optical system, visible as a white, cloudy phenomenon.

Doc. No.: 994-0029 v. 2.0 · Issue date: 26-Aug-2021
Page 2 of 2
ChemoMetec A/S · Gydevang 43 · 3450 Allerod · Denmark · [e-mail] · www.chemometec.com
We recommend to always keep the optical
window/windows in the sample tray clean. To do
so, place a clean swab from the NucleoCounter®
Cleaning Kit on the inner part of the window, then
move it outwards to clean. Repeat the motion for
the entire optical window (see Figure 2).
Figure 2. Demonstration of how to clean the optical
window using a Cleaning Kit swab.
Cleaning a Liquid Spill
Any liquid spilled on the instrument can contaminate elements of the optical system. As there is a risk of
damaging the optical system while attempting to clean it, please consult ChemoMetec’s Support Team at
[email protected] before attempting any cleaning.
Decontamination
In case your NucleoCounter® instrument requires decontamination, please contact ChemoMetec’s Support
Team at [email protected] before taking any action.
Liability Disclaimer
This technical note is for RESEARCH PURPOSES ONLY.
It is not intended for food, drug, household, or
cosmetic use. Its use must be supervised by a
technically qualified individual experienced in handling
potentially hazardous chemicals. The above
information is correct to the best of our knowledge.
Users should make independent decisions regarding
completeness of the information based on all sources
available. ChemoMetec A/S shall not be held liable for
any damage resulting from handling or contact with
the above product.
Product Disclaimer
ChemoMetec A/S reserves the right to introduce
changes in the product to incorporate new
technology. This technical note is subject to change
without notice.
Copyright
Copyright © ChemoMetec A/S 2013. All rights
reserved. No part of this publication may be
reproduced, stored in a retrieval system, or
transmitted in any form or by any means, electronic,
mechanical, photocopying, recording or otherwise,
without the prior written consent of ChemoMetec A/S,
Gydevang 43, DK-3450 Allerod, Denmark.