MPS PHARM/PUMP III User manual

DFU-003 REV C
0509
PHARM/PUMP III
OPERATING INSTRUCTIONS
SOFTWARE VERSION 5.01 or COMPATIBLE

MPS MedicalPharm/Pump IIIOperator Manual V5.01
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MPS MedicalPharm/Pump III Operator Manual V5.01
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CONTENTS
1.0 INTRODUCTION 4
1.1 Key Features 4
1.2 Front Control Panel Layout 5
2.0 INITIAL SETUP 6
2.1 Accessing the User Engineering Setup Mode 6
2.2 Erasing Memory 7
2.3 Selecting UK/US Date Format 7
2.4 Adjusting the Current Date and Time 7
2.5 Printing a Test Label 8
3.0 BASIC OPERATING PRINCIPLES 9
3.1 Setup Memories 9
3.2 Volume Remaining 10
3.3 Preparing for a Dispense 10
4.0 ENTERING SETUP INFORMATION 11
4.1 Entering the Dispense Type 11
4.2 Setting the Amount of Fluid to Dispense 12
4.3 Custom Labels 13
4.4 Setting Drug Name 14
4.5 Setting Drug Lot Number 14
4.6 Setting the Rotor Direction & Speed and Priming the Pump 15
4.7 Setting the Amount of Fluid to Drawback and the Drawback Delay 16
4.8 16
4.9 Calibrating the Pharm/Pump IIITube Flow Constants Setting the Operating Mode 18
4.10 Setting the Auto Mode Count 19
4.11 Re-Setting the Auto Count 19
4.12 Setting the Volume Remaining 20
4.13 Copying a Memory Setup into Another Memory Location 20
4.14 Entering the Volume Remaining 21
4.15 Re-Printing Current Label 22
4.16 Checking the Current Date & Time 22
5.0 PERFORMING A DISPENSE 23
5.1 Manual Dispense 23
5.2 Automatic Dispense 24
5.3 Pausing/Aborting a Dispense 24

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5.4 Calibration On-The-Fly 25
5.5 Operation of the Foot Switch 26
5.6 Opening the Door During a Dispense 26
6.0 LABEL PRINTER 27
6.1 Configuring the Printer 28
Appendix 1 - 29
Appendix 2 - 30
Appendix 3 - 31
Appendix 4 -
SUMMARY OF ERROR MESSAGES
PHARM/Pump III SPECIFICATION
DRUG NAMES
FRONT CONTROL PANEL 34

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1.0 INTRODUCTION
The MPS MedicalPharm/Pump III is an easy to use, microprocessor controlled,
dual mode, quadruple rotor peristaltic pump.
1.1 Key Features
The Pharm/Pump III has the following key features:
Variable Volume
Variable Drawback
Named Drugs
Dual Mode
Calibration
Volume Remain
The pump can be programmed to dispense samples
with a volume of between 1.0 and 4095mL.
At the end of each individual dispense the pump can
be programmed to draw back by a volume of between
0 and 9.9 mL.
The unit contains a comprehensive list of drug names
and concentrations. When the pump is programmed
to dispense one of these named drugs then the
volume of that dispense is automatically fixed at 10.0
mL. In this mode it is also possible to enter a ten digit
lot number. After each dispense a label will be
printed on a suitable label printer. The label will list
the drug name, concentration, volume, date
dispensed and lot number.
The pump can be operated in either manual or
automatic mode. With manual mode a single
dispense is made each time the pump is activated. In
automatic mode a number of dispenses can be made
automatically, each of the same size, with a pre-
programmed time delay between each dispense.
To compensate for variables such as fluid
temperature/density and tube diameter, it is possible
to accurately calibrate the pump. This may be done
when changing setup, or “on the fly” in the middle of a
dispense.
The volume of fluid in the container being dispensed
from can be entered into the Pharm/Pump III. Every
time a dispense is made the dispensed volume will
be subtracted from this original volume, giving a
running total of volume remaining and an advance
warning of incomplete dispenses.

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Setup Memories
Foot Switch
The Pharm/Pump III has twenty-six non-volatile
memories, each of which can store a full set of
operating parameters. Any of these can be recalled
in a moment allowing rapid selection of different
repeated job functions.
A Foot Switch can be connected to the Pharm/Pump
III allowing a hands free start, stop and resume of all
pumping functions. This switch directly mimics the
operation of the START/STOP front panel keys.
Non-Volatile Real Time Clock The MPS MedicalPharm/Pump III has an
internal hardware real time clock which will maintain the
correct date and time, even with the power turned off,
automatically compensating for the number of days in
each month, including during a leap year. The date
information will then be printed on the label when the
pump is in Named Drug dispense mode.
RS232 Serial Port An industry standard RS232 serial port is provided on
the rear of the pump to facilitate the connection of a
label printer.
Custom Labels The unit contains an editor that allows a 20 character
title to be edited, together with an 8 character 2nd line
for concentration values. This, together with the Date,
Volume and Lot Number, is printed after each
dispense. Any volume can be dispensed.
Each memory has a custom label, hence 26 different
labels can be produced.
1.2 Front Control Panel Layout
The front control panel is shown in Appendix 4. It is split into four main areas:
-A 2 line by 20 character LCD display is used to display data, menus,
warning/error messages and soft key functions.
-The 3 rectangular keys located under the display are known as soft function
keys. Their function is denoted by the text located above them on the bottom line
of the LCD display. As menus are navigated the function of these keys will
change to reflect the current operation being performed.

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-Ten number keys, a decimal point and ENTER keys allow direct entry of
numerical data. Four of these keys also have arrow legends on them, which are
used in various menus for selection of data. Note: at no point will it be possible
to use the arrow and the number function simultaneously.
-A START/STOP button at the bottom of the keypad will start and stop the pump
operation for a dispense as well as during priming and calibration operations.
2.0 INITIAL SETUP
2.1 Accessing the User Engineering Setup Mode
NOTE: This operation should only be necessary upon initial delivery of a new
PHARM/Pump III.
The User Engineering Setup Mode is accessed at power up by holding down any key
whilst the power is switched on at the rear of the machine. When the key is released
the display will show the following message:
Enter the system password (default 1212) and the display will show the following
message:
MPS MEDICAL EQUIP SETUP
ENTER PASSWORD:
ERASE MEMORY
ACCEPT NEXT QUIT

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2.2 Erasing Memory
NOTE: THIS SHOULD ONLY BE NECESSARY AFTER MAINTENANCE WORK
OR AFTER A SOFTWARE UPGRADE. THIS OPERATION WILL
ERASE ANY SETTINGS STORED IN THE PHARM/Pump III.
Press the ACCEPTbutton to erase all of the memory locations in the PHARM/Pump
III, the NEXT key to proceed to the next menu item or press the QUIT key to exit to the
main operating menu.
2.3 Selecting UK/US Date Format
The date can be displayed and printed in either American Month/Date/Year format or
European Date/Month/Year format. The current format is displayed on the top line of
the display.
Press the CHANGE button to select the alternative date format.
Press the NEXT key to proceed to the next menu item or press the QUIT key to exit to
the main operating menu.
2.4 Adjusting the Current Date and Time
The next Engineering Setup menu item allows setting of the current date and time. A
dynamic display of the current date and time is given, with the time in standard
Hours:Minutes:Seconds format and the date in either American Month/Date/Year format
or European Date/Month/Year format. The MPS MedicalPharm Pump will
automatically compensate for the number of days in each month, including during a leap
English / US Selected
CHANGE NEXT QUIT
English / UK Selected
CHANGE NEXT QUIT

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year. However, the clock must be altered at the start and end of local daylight saving
time if applicable.
Pressing the CHANGE button places the cursor over the first digit of the time and alters
the soft key definitions as shown below. Note that at this time the clock is frozen so, for
example, a quick alteration of the hours field will also make the time lag behind by how
long it takes to make the alteration.
Typing digits on the keypad overwrites the displayed digits, and the cursor moves to the
right from digit to digit and field to field. Pressing the LEFT and RIGHT buttons moves
the cursor left and right by one display field respectively.
Note: When entering values they will be “clamped” to the nearest sensible number. At
this time no account will be made of the number of days in a month, therefore all
dates will be bound between 1 and 31. This will be corrected at midnight when
the date increments. Care should be taken when setting the date.
2.5 Printing a Test Label
The final menu allows the printing of a test label to confirm the correct function of the
label printer and its interface.
14:55:03 11/14/06
CHANGE NEXT QUIT
14:55:03 11/14/06
CHANGE LEFT RIGHT
Print Test Label
ACCEPT NEXT QUIT

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3.0 BASIC OPERATING PRINCIPLES
The PHARM/Pump III is switched on by pressing the rear panel rocker switch, located
above the main socket. When the PHARM/Pump III has initialized the display will show:
After approximately 1 second, assuming the Erase Memory function above has just
been performed, the display will show:
At this time the display is showing the main top level operating menu. The top line is
indicating that memory “A” has been selected, which contains the setup for a named
drug, the name of which has not yet been specified. The bottom line is telling the
operator to use the up and down arrow keys to select different memory letters, to press
the center soft function key to access the main SETUP menu and to press the right soft
function key to access the auxiliary control MENU. At this moment in time pressing the
left soft function key has no effect.
3.1 Setup Memories
The Pharm/Pump III has 26 setup memory locations referred to by a letter in
the alphabet A-Z. Each memory location holds the following information:
- Rotor direction and speed
- Volume to dispense
- Drawback volume
- Drawback delay
- Dispense mode, auto or manual
- Number of dispenses in an auto operation
- Delay between auto dispenses
- Dispense type
- Drug name or custom label
- Drug batch number
- Volume remaining
- Calibration information
MPS MEDICAL PHARM/Pump III
SOFTWARE VERSION 5.01
A: Unspecified Name
USE  SETUP MENU

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Note: Calibration information is stored within each memory, which means that when
one memory setup is re-calibrated, the other memory locations are unaffected
and hold their original calibration values. If several memories require the same
calibration they must be individually calibrated, or the memories must be copied.
See Section 4.11 for details.
Assuming that one of the stored memories contains valid setup information entered on a
previous session then that memory can be accessed by pressing the up and down keys
on the keypad until the appropriate menu letter is displayed in the top left hand corner of
the display. If the fluid reservoir and pipework has been installed correctly, the
dispensing operation can be initiated simply by pressing either the START/STOP key or
the foot switch.
Note: Holding down the UP/DOWN arrow keys for a moment will activate the auto
repeat function so the memory can be selected more quickly.
3.2 Volume Remaining
The volume of fluid in the container which is being dispensed from can be entered into
the Pharm/Pump III. Every time a dispense is made the dispensed volume will be
subtracted from this original volume, giving a running total of volume remaining. If
there is insufficient fluid to perform the next dispense operation an audible warning will
sound and the user will be prompted whether to abort the operation, continue or alter
the volume remaining figure. It is also possible to abort, change the fluid container,
enter the new volume remaining, re-prime, and then resume the dispense.
If this feature is not required it can be disabled effectively giving an endless volume
remaining.
Note: The volume remaining counter, if enabled, will be decremented for all pumping
operations, whether full dispenses, partial aborted dispenses, during priming or
during calibration.
3.3 Preparing for a Dispense
Before a dispense is performed, the PHARM/Pump III needs to know the following
information:
A) Is the operation to be performed with a fixed drug name 10mL dispense with
printed label?

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If the answer is yes: What is the drug name?
What is the drug batch number?
If the answer is no: What is the fill volume?
What is the fill type?
Is a printed custom label required?
B) What is to be the rotor direction and speed?
C) How much liquid needs to be drawn back at the end of each individual dispense,
and what is the delay between the end of the initial dispense and the start of the
drawback operation?
D) Is the pumping operation to be a multiple dispense in Automatic mode, or a
single dispense in manual mode?
If the answer is Automatic: What is the time delay between fills?
How many fill operations are required?
E) What is the volume of fluid in the reservoir from which dispenses are taken?
4.0 ENTERING SETUP INFORMATION
Once the above information has been determined it can be entered into a memory
location using the SETUP and MENU menus.
At any time when one of the setup menus is displayed, pressing the NEXT soft key will
alter the display to show the next setup menu of that sequence, and pressing the QUIT
soft key will accept all changes made to the currently selected memory and return the
user to the main top level operating menu.
4.1 Entering the Dispense Type
From the main menu, pressing the central SETUP soft function key moves the user
from the main top level operating menu into the SETUP menu. The following display
will typically be visible:
Named Syringe 10ml
TYPE NEXT QUIT

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Pressing the TYPE soft key will cycle the top line of display between the seven different
dispense types. These are:
Named Syringe 10mL - Fixed 10.0mL dispense
- Variable drug name & concentration
- Variable lot number
- Printed Label with drug name,
concentration, date and lot number
Volume - Volume Dispense
-Variable Dispense from 1.0ml to 4095mL
Syringe - Syringe Fill Dispense
-Variable Dispense from 1.0ml to 4095mL
Ambul. - Ambulatory Sphere Fill Dispense
-Variable Dispense from 1.0ml to 4095mL
Trans. - Transfer Fill
-Variable Dispense from 1.0ml to 4095mL
Usage-1 - User type 1 dispense
-Variable Dispense from 1.0ml to 4095mL
Usage-2 - User type 2 dispense
-Variable Dispense from 1.0ml to 4095mL
Custom - Variable dispense from 1.0ml to 4095mL
- Edited title and concentration
- Variable lot number
- Printed label with edited title and
concentration, date and lot number
4.2 Setting the amount of fluid to dispense (Unnamed Drug and custom label
only)
Enter the SETUP menu and select a dispense type which has the ability to dispense a
variable volume of fluid, as indicated in 4.1 above. The number and decimal point keys
will now be activated and it will be possible to enter a new volume between 1.0mL and
4095mL. When the first digit is pressed the volume field will be cleared and a cursor will
be placed over the number being entered. Enter the appropriate digits, then press the

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ENTER key to accept. If the volume is outside the permissible range a warning will be
briefly displayed, then the previous volume will be shown.
Note: Any digits after the first decimal place will be ignored, and all volumes over
999.9mL can only be entered with no decimal places.
4.3 Custom labels
Enter the SETUP menu and select CUSTOM dispense type, as indicated in 4.1 above.
Pressing the NEXT soft key will display the following setup menu screen:
The top line shows the current title that will be printed on the top line of the label by the
printer. To edit this title press the EDIT soft key and the screen will show:
By pressing the left or right arrows the cursor under the first letter will move until you
read the letter you wish to alter.
By pressing the Up/Down arrows the letter can be changed through number, upper and
lower alphabet and some symbols.
This is repeated until the top line has your label (20 characters max).
By pressing the key the display shows:
Unedited label
EDIT NEXT QUIT
Unedited label
 NEXT
CONC: mg/ml
 NEXT

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Again the Up/Down Left Right keys can be used to edit the concentration. Mg/ml is
already installed to save time, however this can be edited out. Please note CONC:
cannot be edited out –it is fixed.
4.4 Setting the Drug Name (Named Drug and custom label only)
Enter the SETUP menu and select the Named Syringe or custom label dispense type as
indicated in 4.1 above. Pressing the NEXT soft key will display the following setup
menu screen:
The top line shows the currently selected drug name. In this example no name has
been previously selected for this memory, so the default “Unspecified Name” drug name
is displayed. Pressing the UP/DOWN arrow keys on the numeric keypad will cycle
through the available list of drug names. Refer to Appendix 3 for a list of drug names
included.
Note: Holding down the UP/DOWN arrow keys for a moment will activate the auto
repeat function so the desired drug name can be selected more quickly.
4.5 Setting Drug Lot Number (Named Drug only)
Enter the SETUP menu and select the Named Syringe dispense type as indicated in 4.1
above. Pressing the NEXT soft key twice will display the following setup menu screen:
The top line shows the lot number from the last time this memory was used. In this
example no lot number has previously been used for this memory, so the default
‘0000000000’ lot number is displayed.
Unspecified Name
Use  NEXT QUIT
Lot No. 0000000000
INC NEXT QUIT

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At this time the number and decimal point keys will be active and it will be possible to
enter a new lot number between 0 and 9999999999. When the first digit is pressed the
Lot Number field will be cleared and a cursor will be placed over the number being
entered. Enter the appropriate digits, then press the ENTER key to accept. Note that
unique to the lot number field, the decimal point key has been re-programmed to
perform as a delete key, deleting the right most digit from the number display and
placing the cursor there ready to enter a new digit.
Also unique to this field, an increment function has been programmed on the left hand
soft key. Pressing this key increments the lot number field by one.
4.6 Setting the Rotor Direction & Speed and Priming the Pump
CAUTION: This procedure inherently involves the pump operating and caution
should be exercised with regard to liquid spillage.
Enter the SETUP menu and press the NEXT soft key several times until a menu similar
to the following screen is displayed:
The top line indicates the current rotor direction and speed. The left hand soft key
allows the toggling of the rotor direction, between CW (Clockwise) and CCW (Counter-
Clockwise).
The number keys will now be activated and it will be possible to enter the two most
significant digits of the rotor speed. The least significant digit is fixed at 0, so speeds
can only be entered in multiples of 10 RPM.
When the first number digit is pressed the most significant digits of the speed field will
be cleared and a cursor will be placed over the number being entered. Enter the
appropriate digits, then press the ENTER key to accept. If the speed entered is outside
the permissible range a warning will briefly be displayed, then the previous speed will be
shown.
Pressing the right most soft key, the START/STOP key or the foot switch will all have
the same effect of starting the pump rotating in the specified direction, at the specified
speed, to enable priming of the tube. This priming will continue indefinitely, until either
the START/STOP key or the foot switch are pressed again.
CW Speed 250 RPM
CCW NEXT PRIME

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4.7 Setting the Amount of Fluid to Drawback and the Drawback Delay
The PHARM/Pump III can automatically draw back volumes from 0 to 9.9mL for each
individual dispense. This volume is added to the dispense volume, then after a
specified delay time the pump draws back as required giving the correct final volume
dispensed. This is a useful feature when filling an item under pressure, for example an
ambulatory sphere, to reduce the pressure in the fill tube prior to disconnection of that
item.
Enter the SETUP menu and press the NEXT soft key until a menu screen similar to the
following is displayed showing the current value for drawback volume:
The number keys and decimal point will now be activated and it will be possible to enter
a drawback volume of between 0.0 and 9.9 mL. When the first number digit is pressed
the field will be cleared and a cursor will be placed over the number being entered.
Enter the appropriate digits, then press the ENTER key to accept. If the volume entered
is outside the permissible range a warning will briefly be displayed, then the previous
value will be shown.
Pressing the DELAY soft key will alter the display to show the current drawback delay
time:
Similar to the drawback volume, it will now be possible to enter a new drawback delay
value from 0.0 to 9.9 seconds using the keypad. Pressing the DB VOL soft function key
will revert to the previous drawback volume screen.
4.8 Calibrating the Pharm/Pump III Tube Flow Constants
The PHARM/Pump III is supplied set up in a default state with flow constants for a
standard MPS Medicalsingle lead pumping chamber set, based on measurements
Drawback 0.5ml
DELAY NEXT QUIT
Drawback Delay 0.3s
DB VOL NEXT QUIT

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taken with water at 20C. If the PHARM/Pump III is used with different tubing
assemblies, or to pump liquids that are at a different temperature and/or have different
viscosity then the PHARM/Pump III can be re-calibrated to take account of this.
Note: The Calibration process requires that the user have an accurate balance
available to ascertain the weight of the dispensed volume of liquid. Calculations
may be necessary to convert from weight in grams to mL based on the viscosity
and temperature of the dispensed liquid.
FOR BEST RESULTS IT IS RECOMMENDED THAT CALIBRATION IS
PERFORMED WITH NO DRAWBACK.
Enter the SETUP menu and press the NEXT soft key several times until a menu screen
similar to the following is displayed showing the current dispense volume:
Pressing the DEFAULT soft key will restore the standard factory calibration as defined
above.
Press the START/STOP key or the foot switch to pump the sample. When the
PHARM/Pump III has finished pumping the display will show:
Ascertain the volume of liquid by weighing, allowing for temperature and viscosity.
Enter the actual volume dispensed in mL up to two decimal places using the numeric
keypad. Press the ENTER key to store the value and recalculate the flow constants.
It is now advisable to repeat the operation by again starting a dispense and determining
its volume as above. Once the measured value is considered acceptable, press NEXT
or QUIT to continue as desired. Otherwise, repeat the operation until the desired
accuracy is achieved.
Note: Drawback volume is automatically calibrated during the same operation.
Calibrate 123.4ml
DEFAULT NEXT QUIT
Actual Vol ml
NEXT QUIT

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4.9 Setting the Operating Mode
The PHARM/Pump III can pump in either manual or auto mode. With manual mode a
single dispense is made each time the pump is activated. In automatic mode a number
of dispenses can be made automatically, each of the same size, with a pre-programmed
time delay between each dispense.
Enter the SETUP menu and press the NEXT key several times until a menu screen is
displayed showing the current dispense mode.
If manual mode is selected the screen will look like:
To change from manual to auto mode press the AUTO key and the display will reflect
the new mode.
If automatic mode is selected the screen will look similar to the following:
To change from auto to manual mode press the MANUAL key, and the display will
reflect the new mode.
At this time the number and decimal point keys will be active and it will be possible to
enter a new Auto Delay between 0.0 and 99.9 seconds. When the first digit is pressed
the Auto Delay field will be cleared and a cursor will be placed over the number being
entered. Enter the appropriate digits, then press the ENTER key to accept. If a value is
entered outside the permissible bounds an error message will briefly be displayed and
then the previous value will be restored.
Manual Mode Selected
AUTO NEXT QUIT
Auto Delay 1.0s
MANUAL NEXT QUIT

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4.10 Setting the Auto Mode Count (Auto Mode Only)
When the PHARM/Pump III is set to automatic mode the operator can enter the
number of times to repeat the dispense between 1 and 999. If the PHARM/Pump III is
set to manual mode this menu is not displayed.
Enter the SETUP menu and press the NEXT key several times until a menu screen is
displayed showing the current count required:
Enter the new count using the numeric keypad and press the ENTER key to store the
new value.
4.11 Re-Setting the Auto Count
As the PHARM/Pump III pumps it maintains a count of how many individual dispenses
have been made in the current operating session. This count functions differently
depending upon the current operating mode.
-In Automatic mode the count is incremented for each individual dispense and is
then automatically reset at the end of the last dispense.
-In manual mode the count is incremented for each individual dispense
indefinitely. If the maximum count of 999 is reached then the count will cycle
back to 0.
To manually reset this counter at any time, enter the SETUP menu and press the NEXT
key until the following menu screen is displayed:
Pressing ACCEPT will reset the counter and a brief message will be flashed on the
display indicating that it has been done.
Count Required 10
NEXT QUIT
Reset Auto Count
ACCEPT NEXT QUIT