MSI X399 SLI PLUS User manual

1
Unpacking
Unpacking
Thank you for buying the MSI®X399 SLI PLUS motherboard. Check to make sure your
motherboard box contains the following items. If something is missing, contact your
dealer as soon as possible.
SLI Bridge
Connector
I/O Shield
Drivers & Utilities
Disc
Motherboard User
Guide
Quick Guide
OC Fan Stand
Motherboard
SATA Cable Labels
SATA Cable x4
RGB LED Extension Cable

2Safety Information
Safety Information
yThe components included in this package are prone to damage from electrostatic
discharge (ESD). Please adhere to the following instructions to ensure successful
computer assembly.
yEnsure that all components are securely connected. Loose connections may cause
the computer to not recognize a component or fail to start.
yHold the motherboard by the edges to avoid touching sensitive components.
yIt is recommended to wear an electrostatic discharge (ESD) wrist strap when
handling the motherboard to prevent electrostatic damage. If an ESD wrist strap is
not available, discharge yourself of static electricity by touching another metal object
before handling the motherboard.
yStore the motherboard in an electrostatic shielding container or on an anti-static pad
whenever the motherboard is not installed.
yBefore turning on the computer, ensure that there are no loose screws or metal
components on the motherboard or anywhere within the computer case.
yDo not boot the computer before installation is completed. This could cause
permanent damage to the components as well as injury to the user.
yIf you need help during any installation step, please consult a certified computer
technician.
yAlways turn off the power supply and unplug the power cord from the power outlet
before installing or removing any computer component.
yKeep this user guide for future reference.
yKeep this motherboard away from humidity.
yMake sure that your electrical outlet provides the same voltage as is indicated on the
PSU, before connecting the PSU to the electrical outlet.
yPlace the power cord such a way that people can not step on it. Do not place anything
over the power cord.
yAll cautions and warnings on the motherboard should be noted.
yIf any of the following situations arises, get the motherboard checked by service
personnel:
Liquid has penetrated into the computer.
The motherboard has been exposed to moisture.
The motherboard does not work well or you can not get it work according to user
guide.
The motherboard has been dropped and damaged.
The motherboard has obvious sign of breakage.
yDo not leave this motherboard in an environment above 60°C (140°F), it may damage
the motherboard.

3
Quick Start
DDR4 Memory
Graphics Card
SATA Hard Disk Drive
SATA DVD Drive
A Package of Screws
Phillips Screwdriver Torqkey Screwdriver
Chassis
Power Supply Unit
Thermal Paste
Quick Start
Preparing Tools and Components
AMD®Ryzen
Threadripper CPU CPU Fan

4Quick Start
CPU
Installing a Processor
https://youtu.be/yk4EpVUU03E
19
12
35
6
4
7
8
9
10
13
11
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5
Quick Start
Installing DDR4 memory
http://youtu.be/T03aDrJPyQs
1
2
2
3
D2 D1 C2 C1 CPU A1 A2 B1 B2
1 DIMM
SocketTR4 CPU
2 DIMMs
4 DIMMs
8 DIMMs

6Quick Start
Connecting the Front Panel Header
http://youtu.be/DPELIdVNZUI
1
2 10
9
JFP1
1 HDD LED + 2 Power LED +
3 HDD LED - 4 Power LED -
5 Reset Switch 6 Power Switch
7 Reset Switch 8 Power Switch
9 Reserved 10 No Pin
RESET SW
POWER SW
POWER LED+
POWER LED-
HDD LED
HDD LED
RESET SW
JFP1
HDD LED HDD LED -
HDD LED +
POWER LED -
POWER LED +
POWER LED

7
Quick Start
Installing the Motherboard
1
2

8Quick Start
Installing SATA Drives
http://youtu.be/RZsMpqxythc
1
23
4
5

9
Quick Start
1
Installing a Graphics Card
http://youtu.be/mG0GZpr9w_A
2
3
4
5
6

10 Quick Start
Connecting Peripheral Devices

11
Quick Start
Connecting the Power Connectors
http://youtu.be/gkDYyR_83I4
ATX_PWR1 CPU_PWR1
CPU_PWR2 PCIE_PWR1

12 Quick Start
Power On
1
4
2
3

13
Contents
Contents
Unpacking .............................................................................................................. 1
Safety Information................................................................................................. 2
Quick Start ............................................................................................................. 3
Preparing Tools and Components.......................................................................... 3
Installing a Processor............................................................................................. 4
Installing DDR4 memory ........................................................................................ 5
Connecting the Front Panel Header....................................................................... 6
Installing the Motherboard..................................................................................... 7
Installing SATA Drives............................................................................................. 8
Installing a Graphics Card...................................................................................... 9
Connecting Peripheral Devices............................................................................ 10
Connecting the Power Connectors....................................................................... 11
Power On............................................................................................................... 12
Specifications....................................................................................................... 15
Block Diagram .................................................................................................... 20
Rear I/O Panel ..................................................................................................... 21
Audio Ports Configuration.................................................................................... 21
LAN Port LED Status Table................................................................................... 21
Realtek HD Audio Manager .................................................................................. 22
Overview of Components .................................................................................... 24
CPU Socket ........................................................................................................... 26
OC1: GAME BOOST Knob ..................................................................................... 29
JSLOW1: Slow Mode Booting Jumper.................................................................. 30
DIMM Slots............................................................................................................ 31
PCI_E1~6: PCIe Expansion Slots.......................................................................... 33
M2_1~3: M.2 Slots (Key M) ................................................................................... 35
SATA1~8: SATA 6Gb/s Connectors ....................................................................... 36
JFP1, JFP2: Front Panel Connectors ................................................................... 36
CPU_PWR1~2, ATX_PWR1, PCIE_PWR1: Power Connectors.............................. 37
JUSB1~2: USB 2.0 Connectors............................................................................. 38
JUSB4~5: USB 3.1 Gen1 Connectors ................................................................... 38
JUSB3: USB 3.1 Gen2 Type-C Connector............................................................. 39
CPU_FAN1, PUMP_FAN1, SYS_FAN1~4: Fan Connectors................................... 40
JAUD1: Front Audio Connector ............................................................................ 40
JCI1: Chassis Intrusion Connector....................................................................... 41
JTPM1: TPM Module Connector........................................................................... 41
JBAT1: Clear CMOS (Reset BIOS) Jumper........................................................... 42
POWER1, RESET1: Power Button, Reset Button ................................................. 42

14 Contents
JRGB1, JRAINBOW1: RGB LED connectors......................................................... 43
Onboard LEDs ...................................................................................................... 44
EZ Debug LED....................................................................................................... 44
DIMM LEDs ........................................................................................................... 44
XMP LED ............................................................................................................... 44
Fan LEDs............................................................................................................... 45
LED light effect demonstration components ....................................................... 45
Debug Code LED................................................................................................... 46
Hexadecimal Character Table .............................................................................. 46
Boot Phases.......................................................................................................... 46
Debug Code LED Table ......................................................................................... 46
ACPI States Codes ................................................................................................ 48
BIOS Setup ........................................................................................................... 49
Entering BIOS Setup............................................................................................. 49
Resetting BIOS...................................................................................................... 50
Updating BIOS....................................................................................................... 50
EZ Mode ................................................................................................................ 52
Advanced Mode .................................................................................................... 54
SETTINGS.............................................................................................................. 55
Advanced............................................................................................................... 55
Boot....................................................................................................................... 59
Security................................................................................................................. 60
Save & Exit............................................................................................................ 61
OC.......................................................................................................................... 62
M-FLASH .............................................................................................................. 66
OC PROFILE.......................................................................................................... 67
Software Description........................................................................................... 68
Installing Windows®10......................................................................................... 68
Installing Drivers .................................................................................................. 68
Installing Utilities ................................................................................................. 68
APP MANAGER ..................................................................................................... 69
LIVE UPDATE 6...................................................................................................... 70
COMMAND CENTER ............................................................................................. 72
X-BOOST ............................................................................................................... 76
MYSTICLIGHT........................................................................................................ 78
MSI SMART TOOL ................................................................................................. 80
RAMDISK............................................................................................................... 82
NETWORK MANAGER........................................................................................... 83
CPU-Z.................................................................................................................... 85
Troubleshooting .................................................................................................. 86

15
Specifications
Specifications
CPU Supports AMD®Ryzen Threadripper processor for SocketTR4
Chipset AMD® X399 Chipset
Memory
y8x DDR4 memory slots, support up to 128GB*
yQuad channel memory architecture**
ySupports DDR4 3600+(OC)/ 3466(OC)/ 3333(OC)/ 3200(OC)/
3066(OC)/ 2933(OC)/ 2800(OC)/ 2667(OC)/ 2400/ 2133 MHz*
* For the latest information about memory, please visit http://www.msi.com
** Please refer the DIMM Slots section for more details.
Expansion Slots y4x PCIe 3.0 x16 slots
y2x PCIe 2.0 x1 slots
Multi-GPU ySupports 4-Way NVIDIA®SLI™Technology
ySupports 4-Way AMD®CrossFire™Technology
LAN 1x Intel I211 Gigabit LAN controller
Storage
yAMD®X399 Chipset
8x SATA 6Gb/s ports*
yAMD®CPU
3x M.2 slots (Key M)*
Supports up to PCIe 3.0 x4 and SATA 6Gb/s
M2_1, M2_3 slots support 2242/ 2260 /2280 storage
devices
M2_2 slot supports 2242/ 2260 /2280/ 22110 storage
devices
RAID
AMD®X399 Chipset
ySupports RAID 0, RAID 1 and RAID 10 for SATA storage
devices
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16 Specifications
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USB
yASMedia®ASM3142 Chipset
1x USB 3.1 Gen2 (SuperSpeed USB 10Gbps) Type-C port
on the back panel
1x USB 3.1 Gen2 (SuperSpeed USB 10Gbps) Type-A port
on the back panel
yAMD®X399 Chipset
1x USB 3.1 Gen2 (SuperSpeed USB 10Gbps) Type-C port
through the internal USB connector
4x USB 3.1 Gen1 (SuperSpeed USB) ports available
through the internal USB connectors
6x USB 2.0 (High-speed USB) ports (2 Type-A ports on
the back panel, 4 ports available through the internal
USB connectors)
yAMD®CPU
8x USB 3.1 Gen1 (SuperSpeed USB) Type-A ports on the
back panel
Audio
yRealtek®ALC1220 Codec
y7.1-Channel High Definition Audio
ySupports S/PDIF output
Back Panel
Connectors
y1x Clear CMOS button
y1x BIOS FLASHBACK+ button
y1x PS/2 keyboard/ mouse combo port
y2x USB 2.0 Type-A ports
1x BIOS FLASHBACK+ port
y8x USB 3.1 Gen1 Type-A ports
y1x LAN (RJ45) port
y1x USB 3.1 Gen2 Type-A port
y1x USB 3.1 Gen2 Type-C port
y5x OFC audio jacks
y1x Optical S/PDIF OUT connector
Continued on next page

17
Specifications
Continued from previous page
Internal Connectors
y1x 24-pin ATX main power connector
y2x 8-pin ATX 12V power connector
y1x 6-pin ATX 12V power connector*
y8x SATA 6Gb/s connectors
y2x USB 2.0 connectors (supports additional 4 USB 2.0
ports)
y2x USB 3.1 Gen1 connectors (supports additional 4 USB 3.1
Gen1 ports)
y1x USB 3.1 Gen2 Type-C port
y1x 4-pin CPU fan connector
y1x 4-pin Water Pump connector
y4x 4-pin system fan connectors
y2x Front panel connectors
y1x Front panel audio connector
y2x RGB LED connector
y1x TPM module connector
y1x LED demo connector
* Provides additional power to PCIe x16 slots
Internal Buttons
y1x GAME BOOST knob
y1x Power button
y1x Reset button
y1x LED demo button
Jumper
y1x Clear CMOS jumper
y1x Chassis Intrusion connector
y1x Slow mode booting jumper
Debug LED y1x 2-Digit Debug Code LED
I/O Controller NUVOTON NCT6795 Controller Chip
Hardware Monitor
yCPU/System temperature detection
yCPU/System fan speed detection
yCPU/System fan speed control
Form Factor yATX Form Factor
y12 in. x 9.6 in. (30.4 cm x 24.3 cm)
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18 Specifications
Continued from previous page
BIOS Features
y1x 128 Mb flash
yUEFI AMI BIOS
yACPI 6.0, SM BIOS 3.0
yMulti-language
Software
yDrivers
yAPP MANAGER
ySUPER CHARGER
yCOMMAND CENTER
yLIVE UPDATE 6
ySMART TOOL
yX-BOOST
yMYSTIC LIGHT
yRAMDISK
yNETWORK MANAGER
yCPU-Z MSI GAMING
yNorton™ Internet Security Solution
yGoogle Chrome™ ,Google Toolbar, Google Drive
Continued on next page

19
Specifications
Continued from previous page
Special Features
Audio Boost 4
Triple Turbo M.2
Pump Fan
Smart Fan Control
Mystic Light
Mystic Light Extension
Mystic light SYNC
EZ DEBUG LED
M.2 Shield
PCI-E Steel Armor
Multi GPU – SLI Technology
Multi GPU – CrossFire Technology
DDR4 Boost
GAME Boost (go to 11)
OC Engine (Clock gen)
USB with type A+C
Lightning USB (3142)
Front Lightning USB (20PIN)
7000+ Quality Test
VR Ready
Click BIOS 5
BIOS FLASHBACK+
FirePro ready

20 Block Diagram
Block Diagram
x2
2/ 4 Channel DDR4 Memory
2x USB 3.1 Gen2
1x USB 3.1 Gen2 Type C
3x M.2
PCIE Bus
PCIE Bus
Intel I211
Gigabit LAN
DMI 3.0
PCI Express Bus
X399
Processor
NV6795
Super I/O
Realtek
ALC1220
Intel
8265 WiFi
8x SATA 6Gb/s
4x USB 3.1 Gen1
6x USB 2.0
8x USB 3.1 Gen1
PCIe x1 slot
PCIe x1 slot
ASMEDIA
ASM3142
Audio Jacks
P/S2 Mouse / Keyboard