BioNano Genomics Saphyr System Installation and operating manual

For Research Use Only. Not for use in diagnostic procedures.
Copyright © 2019 Bionano Genomics Inc. All Rights Reserved
Saphyr®System Safety Guide
for Saphyr P/N 60325
Document Number: 30253
Document Revision: A

30253 Rev A, Saphyr System Safety Guide for Saphyr P/N 60325 Page 2 of 9
Table of Contents
Legal Notice............................................................................................................................... 3
Revision History......................................................................................................................... 4
Saphyr System Safety Guide..................................................................................................... 5
Important................................................................................................................................ 5
Safety Warnings..................................................................................................................... 5
Laser Safety Warnings........................................................................................................... 6
Preventing Radiation Exposure........................................................................................... 6
Safety Labeling ................................................................................................................... 6
Sound Level Safety Warnings................................................................................................ 7
LED Exposure Warning.......................................................................................................... 7
Electrical Safety Warnings...................................................................................................... 7
Electrical Specifications ...................................................................................................... 7
Uncrating, Installing and Moving the Instrument..................................................................... 7
Dimensions ......................................................................................................................... 8
Environmental Considerations................................................................................................ 8
Technical Assistance................................................................................................................. 9

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Legal Notice
For Research Use Only. Not for use in diagnostic procedures.
This material is protected by United States Copyright Law and International Treaties. Unauthorized use of this
material is prohibited. No part of the publication may be copied, reproduced, distributed, translated, reverse-
engineered or transmitted in any form or by any media, or by any means, whether now known or unknown,
without the express prior permission in writing from Bionano Genomics. Copying, under the law, includes
translating into another language or format. The technical data contained herein is intended for ultimate
destinations permitted by U.S. law. Diversion contrary to U. S. law prohibited. This publication represents the
latest information available at the time of release. Due to continuous efforts to improve the product, technical
changes may occur that are not reflected in this document. Bionano Genomics reserves the right to make
changes in specifications and other information contained in this publication at any time and without prior notice.
Please contact Bionano Genomics Customer Support for the latest information.
BIONANO GENOMICS DISCLAIMS ALL WARRANTIES WITH RESPECT TO THIS DOCUMENT, EXPRESSED
OR IMPLIED, INCLUDING BUT NOT LIMITED TO THOSE OF MERCHANTABILITY OR FITNESS FOR A
PARTICULAR PURPOSE. TO THE FULLEST EXTENT ALLOWED BY LAW, IN NO EVENT SHALL BIONANO
GENOMICS BE LIABLE, WHETHER IN CONTRACT, TORT, WARRANTY, OR UNDER ANY STATUTE OR ON
ANY OTHER BASIS FOR SPECIAL, INCIDENTAL, INDIRECT, PUNITIVE, MULTIPLE OR CONSEQUENTIAL
DAMAGES IN CONNECTION WITH OR ARISING FROM THIS DOCUMENT, INCLUDING BUT NOT LIMITED
TO THE USE THEREOF, WHETHER OR NOT FORESEEABLE AND WHETHER OR NOT BIONANO
GENOMICS IS ADVISED OF THE POSSIBILITY OF SUCH DAMAGES.
Patents
Products of Bionano Genomics may be covered by one or more U.S. or foreign patents.
Trademarks
The Bionano Genomics logo and names of Bionano Genomics products or services are registered trademarks or
trademarks owned by Bionano Genomics in the United States and certain other countries.
Bionano Genomics®, Saphyr®, Saphyr Chip®, and Bionano Access® are trademarks of Bionano Genomics, Inc.
All other trademarks are the sole property of their respective owners.
No license to use any trademarks of Bionano Genomics is given or implied. Users are not permitted to use these
trademarks without the prior written consent of Bionano Genomics. The use of these trademarks or any other
materials, except as permitted herein, is expressly prohibited and may be in violation of federal or other applicable
laws.
© Copyright 2019 Bionano Genomics, Inc. All rights reserved.

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Revision History
Revision
Notes
A
Initial Release

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Saphyr System Safety Guide
For Research Use Only. Not for use in diagnostic procedures.
This guide provides important safety information pertaining to the installation, servicing, and operation of the
Bionano Genomics® Saphyr® System (PN 60325). Read this document before performing any procedures on the
system.
If the equipment is used in a manner not specifiedby the manufacturer, the protection provided by the equipment
may be impaired.
Important
You must read the Saphyr Site Preparation Guide and Saphyr System User Guide before plugging the instrument
into the power supply.
Before the installation day, we recommend that you familiarize yourself with the relevant safety and installation
instructions provided in the following documents.
These documents contain information and warnings that must be followed by the customer for safe operation and
for keeping the product in a safe condition. Before use of the instrument, please review all safety instructions to
avoid injury and prevent damage to this instrument and any products connected to it.
The following documents are available for download from www.bionanogenomics.com.
Resource Description
Saphyr Site Preparation Guide Provides specifications for laboratory space,
electrical requirements, and environmental
considerations.
Saphyr System User Guide Provides an overview of instrument components and
software, proper maintenance, and troubleshooting.
Bionano Access Software Guide Provides an overview of data analysis.
Safety Warnings
Make sure that all personnel are trained in the correct operation of the instrument and any potential safety
considerations.
Type Description
Hazard: Indicates a potential electrical shock hazard
that may lead to personal injury
Hazard: Indicates a potential laser exposure hazard
that may lead to personal injury

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Laser Safety Warnings
The Saphyr system has a laser system classification of a Class 1 product, which uses embedded Class 3B and
one Class 4 laser. The Saphyr System is certified to the IEC 60825-1:2014 standards.
The nominal wavelength outputs include the following optical power:
•500 mW (532 nm)
•140 mW (637 nm, 2 each)
•400 mW (488 nm)
•90 mW (785 nm)
A Class 1 laser product is safe under all conditions of normal use.
A Class 4 laser product is hazardous if the eye is directly exposed to the laser. However, the diffuse reflections
are not harmful. Protective eye wear is required when a person is viewing a class 3B laser beam. All Class 4
lasers must be equipped with a key switch and a safety interlock.
Preventing Radiation Exposure
•Do not open the front panel of the instrument because you could come into contact with a Class 4 laser.
•If you operate the instrument with any panels removed, you risk radiation exposure from the direct or
reflected laser light.
•If you use controls or make adjustments that are not specified in The Saphyr Safety Guide, you can be
exposed to hazardous radiation.
Safety Labeling
Figure 1: Class 4 Laser Warning

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Sound Level Safety Warnings
The instrument produces sounds when operated. All noise is under 85 dBA (the OSHA limit for safety).
LED Exposure Warning
Do not gaze at the light-emitting diode (LEDs) on the front of the instrument for an extended period of time.
Exposure to high-intensity LED may increase the risk of vision impairment and discomfort.
Electrical Safety Warnings
•Do not remove the outer panels from the instrument. Operating the instrument without all of the panels
creates potential exposure to hazardous AC and DCvoltages.
•For protection against electrical shock hazard, the instrument must be plugged intoa three-wired grounded
receptacle.
•Do not attach the power cord to an extension cord or to a multiple portablesocket.
•Donot connect the instrumentto anything.
•Do not open the sample door during scanning, as this could expose potentially hazards.
•Only Bionano Field Service Engineers or Bionano certified personnel are qualified to replace the internal
fuses. The power entry module includes two input fuses on the high-voltageinput lines.
•Under no circumstances should the user modify the safety features of thisinstrument.
Electrical Specifications
Type Specification
Line Voltage 100–240 VAC at 50/60 Hz
Power Consumption (instrument,
instrument controller, and monitor) ≤ 300 Watt
Power Connector The instrument is shipped with only power cords for
North America. The necessary power cords required
for all other countries are provided at set-up.
Uncrating, Installing and Moving the Instrument
CAUTION: Only an authorized Bionano personnel can uncrate and install the instrument.
The instrument is heavy and can cause serious injury if dropped or mishandled. Make sure there are three people
to assist the Field Service Engineer with lifting the Saphyr instrument from the crate. Ensure that the power
outlets powering the instrument are easily accessible and free of any obstructions.
Significant risks to optical and mechanical alignment can occur if the instrument is moved.

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Ensure the instrument is installed on a clean, sturdy, level, bench without exposure to direct sunlight or heat
sources.
Do not set the instrument up where liquid or chemicals are used. Ensure that no liquids are spilled into the
instrument.
Do not operate the instrument in the presence of flammable gases or fumes.
Dimensions
Measurement Instrument
Height 38 cm (15 in)
Width 86 cm (34 in)
Depth 71 cm (28 in)
Weight 103 kg (227 lb)
Environmental Considerations
This instrument is designed for indoor use only.
Element Specification
Temperature Maintain a lab temperature of 19°C (66°F) to 25°C
(77°F).
Humidity Maintain a noncondensing relative humidity between
20–80%.
Elevation The instrument may only be operated at a location
where the elevation is 2,000m (6,500 ft) or less above
mean sea-level.
Ventilation
Provide at least 5 cm (2 in) of clearance behind the
instrument to allow sufficient ventilation and access
to instrument power connection.
Overhead clearance required for installation and
service is 93 cm (37 inch).
Air Quality
Operate the instrument in a Pollution Degree II
environment or better.

Technical Assistance
For technical assistance, contact Bionano Genomics Technical Support.
You can retrieve documentation on Bionano products, SDS's, certificates of analysis, frequently asked questions,
and other related documents from the Support website or by request through e-mail and telephone.
Type Contact
Email [e-mail]
Phone Hours of Operation:
Monday through Friday, 9:00 a.m. to 5:00 p.m., PST
US: [phone]
Website www.bionanogenomics.com/support
Bionano Genomics, Inc.
9540 Towne Centre Drive, Suite 100
San Diego, CA 92121