Bruker minispec LF Series User manual

minispec
minispec LF-series
User Manual
Version 002
Innovation with Integrity
●
AIC

Copyright © by Bruker Corporation
All rights reserved. No part of this publication may be reproduced, stored in a retrieval
system, or transmitted, in any form, or by any means without the prior consent of the
publisher. Product names used are trademarks or registered trademarks of their re-
spective holders.
© May 16, 2019 Bruker BioSpin GmbH
Document Number: 10000058222
P/N: E164809

Contents
E164809_2_002 iii
Contents
1 Introduction.........................................................................................................................................5
1.1 Policy Statement .................................................................................................................7
2 Safety...................................................................................................................................................9
2.1 Intended Use.......................................................................................................................9
2.2 Qualified Personnel.............................................................................................................9
2.3 Correct Usage.....................................................................................................................9
2.4 General Workplace Dangers.............................................................................................10
2.4.1 Lifting Safety .....................................................................................................................10
2.4.2 Safety When Working with Glassware..............................................................................10
2.5 Dangers from Electrical Power .........................................................................................11
2.6 Dangers from Magnetic Fields ..........................................................................................12
2.6.1 Example Stray Field Plots.................................................................................................12
3 Transport, Packaging and Storage .................................................................................................15
3.1 Symbols on the Packaging ...............................................................................................15
3.2 Inspection at Delivery........................................................................................................16
3.3 Packaging .........................................................................................................................16
3.4 Storage .............................................................................................................................17
4 Design and Function ........................................................................................................................19
4.1 Brief Description................................................................................................................19
4.2 Unit Description.................................................................................................................19
4.3 Movable Working Table (Cart) ..........................................................................................20
5 Installation.........................................................................................................................................21
5.1 Siting Considerations ........................................................................................................21
5.1.1 Environmental Considerations ..........................................................................................21
6 Operation...........................................................................................................................................23
6.1 Turning the Unit On...........................................................................................................23
6.2 minispec Software GUI .....................................................................................................23
6.2.1 Wake-up State of the minspec.exe Software....................................................................23
6.2.2 Changing the Software Configuration ...............................................................................23
6.2.2.1 Selecting Applications and Connections...........................................................................24
6.2.2.2 Changing Analyser Type and Calibration Permission.......................................................24
6.2.3 The minispec Standard Windows .....................................................................................24
6.2.3.1 The Signal Window ...........................................................................................................25
6.2.3.2 The Results Window .........................................................................................................25
6.2.3.3 The Spreadsheet Window.................................................................................................25
6.2.4 minispec.exe Menu Functions ..........................................................................................26
6.2.4.1 The Bars ...........................................................................................................................26
6.2.4.2 The File Menu ...................................................................................................................27
6.2.4.3 The Edit Menu...................................................................................................................31
6.2.4.4 The minispec Menu...........................................................................................................32
6.2.4.5 The Measurement Menu...................................................................................................35

Contents
iv E164809_2_002
6.2.4.6 The Parameter Menu ........................................................................................................37
6.2.4.7 The View Menu .................................................................................................................40
6.2.4.8 The Process Menu............................................................................................................44
6.2.4.9 The Window Menu ............................................................................................................45
6.2.4.10 The Help Menu .................................................................................................................46
6.3 Running minispec Plus Software ......................................................................................47
6.3.1 Daily Check.......................................................................................................................48
6.4 General Measurement Handling .......................................................................................49
7 Basic NMR Principles.......................................................................................................................51
8 NMR Parameters...............................................................................................................................53
8.1 Scans ................................................................................................................................53
8.2 Recycle Delay Time ..........................................................................................................53
8.3 Gain ..................................................................................................................................53
8.4 Acquisition Pre-Delay Time...............................................................................................54
8.5 Dummy Shots ...................................................................................................................54
9 Maintenance......................................................................................................................................55
9.1 Cleaning............................................................................................................................55
10 Replacement of Parts.......................................................................................................................57
10.1 Returning the Unit for Repair ............................................................................................57
11 Dismantling and Disposal................................................................................................................59
11.1 Dismantling .......................................................................................................................59
11.2 Disposal in Europe............................................................................................................59
11.3 Disposal in USA and Other (non-EU) Countries ...............................................................60
12 Technical Data ..................................................................................................................................61
12.1 General Information ..........................................................................................................61
12.2 Connection Values............................................................................................................61
12.3 Operating Conditions ........................................................................................................63
12.4 Rating Plate ......................................................................................................................63
13 Contact ..............................................................................................................................................65
List of Figures...................................................................................................................................67
Index ..................................................................................................................................................69

Introduction
E164809_2_002 5 / 72
1 Introduction
The minispec LF-series is a benchtop Nuclear Magnetic Resonance (NMR) analyzer for
detection of hydrogen (1H), fluorine (19F), and other abundant NMR-active nuclei. Its common
application is in polymer, chemical and agrifood industry quality control and quality assurance
(QC/QA), where it is routinely used for fast, reproducible and non-destructive analysis. The
minispec LF-series is also used for a diverse range of applications in research and
development (R&D) laboratories in industry, universities, and medical research facilities.
This manual provides instructions on the initial installation of the instrument by Bruker Service
or personnel authorized by Bruker, including:
• Siting Considerations.
• Unpacking the System.
• Assembling the Cart.
• Assembling the Analyzer Unit.
• Analyzer Unit Connections.
• Electronic Control and the Magnet Unit Connections.
• Electronic Control, Magnet and Gradient Unit Connections.
• Connecting the PC to the minispec.
• Powering Up the System.
• Software Installation.
Instructions on proper operation of the minispec Analyzer and an introduction to the use of
the minispec hardware and software are provided.
Users who want to familiarize themselves with the minispec capabilities will benefit from the
software introduction in the section minispec Software GUI.
To provide a better understanding of the principles involved, an introduction to the basics of
NMR is provided in section Basic NMR Principles [}51]. A minimum set of NMR parameters
is described in NMR Parameters [}53].
The minispec LF-series Analyzers operate with the minispec Plus LF software, which is
delivered with the system. This is a modern software package and there are separate
manuals available on the minispec software USB stick that explain the operation of the
software in all details:
• minispec Plus Administration
• minispec Plus Classic
• minispec Plus Chemometrics
The minispec.exe software is the data acquisition software, running in the background of
minispec Plus LF. However minispec.exe is mainly used for diagnostic purposes / service on
the LF-series systems.
This manual enables safe and efficient handling of the device.
This manual is an integral part of the device, and must be kept in close proximity to the
device where it is permanently accessible to personnel. In addition, instructions concerning
labor protection laws, operator regulations tools and supplies must be available and adhered
to.
Before starting any work, personnel must read the manual thoroughly and understand
its contents. Compliance with all specified safety and operating instructions, as well as local
work safety regulations, are vital to ensure safe operation.

Introduction
6 / 72 E164809_2_002
The figures shown in this manual are designed to be general and informative and may not
represent the specific Bruker model, component or software/firmware version you are
working with. Options and accessories may or may not be illustrated in each figure.
This service manual is the technical documentation for Bruker Service technicians.
Before starting any work, personnel must read the manual thoroughly and understand its
contents. Compliance with all specified safety and operating instructions, as well as local
work safety regulations, are vital to ensure safe operation.
The figures shown in this manual are designed to be general and informative and may not
represent the specific Bruker model, component or software/firmware version you are
working with. Options and accessories may or may not be illustrated in each figure.

Introduction
E164809_2_002 7 / 72
1.1 Policy Statement
It is Bruker’s policy to improve products as new techniques and components become
available. Bruker reserves the right to change specifications at any time.
Every effort has been made to avoid errors in text and figure presentation in this publication.
In order to produce useful and appropriate documentation, we welcome your comments on
this publication. Field Service Engineers are advised to check regularly with Bruker for
updated information.
Bruker is committed to providing customers with inventive, high-quality, environmentally-
sound products and services.

Introduction
8 / 72 E164809_2_002

Safety
E164809_2_002 9 / 72
2 Safety
This manual contains notices which should be observed to ensure your own personal safety
as well as to protect the spectrometer and the connected equipment.
2.1 Intended Use
The minispec LF-series is a pulsed time-domain NMR analyzer used for the monitoring of the
hydrogen nuclei.
This product is intended to be used solely for measurements on industrial samples. The
minispec LF-series has not been tested for compliance with regulatory agencies for human
subject exposure to radio frequency irradiation. Although no indication that any danger exists,
under no circumstance is this product intended for measurements on humans.
2.2 Qualified Personnel
The minispec LF-series may only be set up and operated in conjunction with the instructions
in this manual. Only qualified personnel should be allowed to work on this equipment. The
primary installation, maintenance and repair of the minispec LF-series may only be carried
out by personnel which are authorized by Bruker.
All repairs, adjustments and alignments performed on any components of the minispec must
be carried out strictly in accordance with the established safety practices and standards of
the country where the instrument is installed.
2.3 Correct Usage
This device and its components may only be used in the way discussed with a Bruker
specialist and in connection with devices or components from other manufacturers which
have been approved or recommended by Bruker.
This product can only function correctly and safely if it is transported, stored, set up and
installed correctly, and operated and maintained as recommended by Bruker.

Safety
10 / 72 E164809_2_002
2.4 General Workplace Dangers
2.4.1 Lifting Safety
The standard magnet unit may weigh up to 150 kg depending on the type of analyzer, to
ensure safety the follow safety instructions must be followed:
kg
CAUTION
Risk of injury from lifting heavy objects.
The unit is very heavy and may lead to injury when lifting.
uDo not attempt to lift the unit over the edge of the carton, remove the carton first.
uDo not attempt to lift the unit on your own or without necessary precaution against
injury.
uUse a hoist if available.
2.4.2 Safety When Working with Glassware
WARNING
Danger of injury from glassware or ceramics breakage!
Broken glassware or ceramics may cause minor injuries or material damage, but may also
result in a life threatening situation if hazardous substances are used.
uIf glassware or ceramics breaks, refer to the corresponding precautions and cleaning/
disinfection instructions.
uWear protective equipment.
uPerform all tasks with the glassware or ceramics carefully.
uBefore carrying out any maintenance work, remove the samples and use dummy
samples if necessary.
uStrictly observe the correct sample adjustment, i.e. the maximum sample height.
uAlways transport the glassware or ceramics with the cover, if applicable. Never turn the
glassware or ceramics upside down or on it’s side.
uThe laboratory supervisor is responsible for:
ðEstablishing and enforcing standard sample handling and cleaning procedures.
ðEstablishing and enforcing the use of protective clothing and equipment.
ðTraining laboratory personnel.
ðPreparing an emergency plan.

Safety
E164809_2_002 11 / 72
2.5 Dangers from Electrical Power
There is no danger of electrical shock during routine operation of the spectrometer, however
the following precautions must be followed to assure user safety and protection of the
instrument.
WARNING
Electrical hazard from electrical shock
A life threatening shock may result when maintenance is performed.
uPlace the mains power switch in the OFF position (direction labeled "0" on the switch).
uDisconnect the device from the electrical power supply before maintenance. Use a
voltmeter to verify that the device is not under power!
uBe sure that the power supply cannot be reconnected without notice.
uEnsure that all warning labels are in place.
uOnly trained personnel should carry out maintenance.
The safety precautions applicable to any electronic device connected to AC power must be
observed.
Always use the power cable that is delivered with the product.
If replacement of the power cable is necessary, make sure that the ratings with regard to the
power consumption of the device are suitable.
WARNING
Electrical hazard from stored electrical charge
A life threatening shock or material damage may result from a stored electrical charge.
Never touch electrical contacts or semiconductor chips with any object (conductive or non-
conductive) unless all of the following conditions are met:
uThe power switch is off.
uThe power plug is disconnected from either the power socket or the main power socket
on the spectrometer.
uThe conductive object and you are grounded.
ðThis precaution prevents the possibility of electrical shock from stored charge within the
power supply circuitry or the transfer of static charge that can damage semiconductor
chips.
No other components within the spectrometer should be touched (even with the power off)
without first contacting a Bruker service representative to obtain all necessary instructions, to
ensure user and spectrometer safety.

Safety
12 / 72 E164809_2_002
2.6 Dangers from Magnetic Fields
The instrument contains strong magnetic fields, some of which extend beyond the magnet
unit house (see stray field diagram below). These pose no danger to routine users, but are
hazardous to persons with heart pacemakers or other medical implantations.
WARNING
Risk to life due to high magnetic fields
A magnetic field of more than 0.5mT (5Gauss) is life-threatening for people with
pacemakers or active metal implants. Exposure to more than 8T can cause damage to
health. Duration of exposure (8h/day) above the limit of 200mT can cause damage to
health. Ferromagnetic tools in the magnetic field are significantly hazardous. Disks and
electronic devices may be damaged.
uMark the magnetic field of more than 0.5mT (5Gauss) before start up.
uKeep people with active medical implants or heart pacemakers away from the 0.5mT
(5Gauss) area.
uThe permanent workplace of employees must be outside the 0.5mT (5Gauss) area.
uDo not stay or work at magnetic fields of more than 8T.
uPrevent exposure of more than 200mT for more than 8h/day.
uKeep disks, credit cards and electronic devices away from the identified area.
uDo not use ferromagnetic tools or items within the identified area.
uOnly use non-ferromagnetic transportation dewars or pressure cylinders for the
cryogenic agents.
uOnly use non-ferromagnetic ladders or steps.
uRemove magnetic items (jewelry, watches, pens etc.) before carrying out maintenance
work.
2.6.1 Example Stray Field Plots
Figure2.1: Example of a Stray Field Plot for the LF90 - Front View

Safety
E164809_2_002 13 / 72
Figure2.2: Example of a Stray Field Plot for the LF90 - Top View

Safety
14 / 72 E164809_2_002

Transport, Packaging and Storage
E164809_2_002 15 / 72
3 Transport, Packaging and
Storage
Installation, initial commissioning, retrofitting, repairs, adjustments or dismantling of the
device must only be carried out by Bruker Service or personnel authorized by Bruker.
Damage due to servicing that is not authorized by Bruker is not covered by your warranty.
3.1 Symbols on the Packaging
The following symbols are affixed to the packaging material. Always observe the symbols
during transport and handling.
Top The arrow tips on the sign mark the top of the
package. They must always point upwards;
otherwise the content may be damaged.
Fragile Marks packages with fragile or sensitive
contents.
Handle the package with care; do not allow the
package to fall and do not allow it to be
impacted.
Protect Against Moisture Protect packages against moisture and keep
dry.
Attach Here Lifting gear (lifting chain, lifting strap) must
only be attached to points bearing this symbol.
Center of Gravity Marks the center of gravity of packages.
Note the location of the center of gravity when
lifting and transporting.
Weight, Attached Load Indicates the weight of packages.
Handle the marked package in accordance
with its weight.
Permitted Stacking Load Indicates packages which are partially
stackable.
Do not exceed the maximum load-bearing
capacity specified on the symbol in order to
avoid damaging or destroying the content.

Transport, Packaging and Storage
16 / 72 E164809_2_002
Do not Damage Air-tight
Packaging
The packaging is air-tight. Damage to the
barrier layer may render the contents
unusable.
Do not pierce.
Do not use sharp objects to open.
Component Sensitive to
Electrostatic Charge
The packaging contains components which
are sensitive to an electrostatic charge.
Only allow packaging to be opened by trained
personnel.
Establish potential equalisation before
opening.
Protect from Heat Protect packages against heat and direct
sunlight.
Protect from Heat and
Radioactive Sources
Protect packages against heat, direct sunlight
and radioactive sources.
Table3.1: Symbols on the Packaging
3.2 Inspection at Delivery
Upon receipt, immediately inspect the delivery for completeness and transport damage.
Proceed as follows in the event of externally apparent transport damage:
• Do not accept the delivery, or only accept it subject to reservation.
• Note the extent of the damage on the transport documentation or the shipper's delivery
note.
• Initiate complaint procedures.
Issue a complaint in respect to each defect immediately following detection. Damage
compensation claims can only be asserted within the applicable complaint deadlines.
3.3 Packaging
The LF65/LF90/LF110 will arrive with two pallets with dimensions:
• 99 x 89 x 150 cm (w x h x d)
Weight ca. 460 kg / LF110 ca. 530 kg.
• 87 x 71 x 78 cm (w x h x d)
Weight ca. 40 kg.
If the PC is purchased with the instrument, it will arrive in a separate package. The size and
weight of this package may vary.
To move the main minispec package to its installation site you will need:
• A fork lift truck or pallet hoist.

Transport, Packaging and Storage
E164809_2_002 17 / 72
It is recommended to store the packaging for later use in the event that you need to return the
unit to Bruker.
Handling Packaging Materials
Dispose of packaging material in accordance with the relevant applicable legal requirements
and local regulations
3.4 Storage
Storage of the Packages
Store the packages under the following conditions:
• Do not store outdoors.
• Store in dry and dust-free conditions.
• Do not expose to aggressive media.
• Protect against direct sunlight.
• Avoid mechanical shocks.
• Storage temperature: 15 to 35 °C.
• Relative humidity: max. 60%.
• If stored for longer than 3 months, regularly check the general condition of all parts and
the packaging. If necessary, top-up or replace preservatives.
Under certain circumstances, storage instructions may be affixed to packages which expand
the requirements specified here. Comply with these accordingly.

Transport, Packaging and Storage
18 / 72 E164809_2_002

Design and Function
E164809_2_002 19 / 72
4 Design and Function
The minispec LF-series is a benchtop system for time-domain nuclear magnetic resonance
(TD-NMR) measurements primarily assigned for quality control. The system consists of a
magnet and an electronic unit, a PC workstation, the user software and optionally a pulsed
gradient unit, automation, a printer, a balance or a bar-code reader. The delivery scope
contains a data medium (USB stick) including the technical documentation, that informs
provides information about the system requirements, the setup procedure, as well as the user
software including all default settings and the user documentation.
4.1 Brief Description
All systems of the minispec LF product range have an integrated basic probe module, where
the respective sample is positioned using a so-called sample restrainer. The minispec LF90II
and the LF110 system have a probe-in-probe technique. This technique enables the usage of
special probes which are put in the basic probe module.
4.2 Unit Description
The minispec LF-series is available in several models:
• minispec LF50 measurement system for samples up to 60-70 grams.
• minispec LF50H (horizontal) measurement system for samples up to 60-70 grams.
• minispec LF90II measurement system for samples up to ~800 grams.
• minispec LF110 measurement system for samples > 1 kg.
Figure4.1: The minispec LF50 Analyzer
Figure4.2: The minispec LF50H Analyzer

Design and Function
20 / 72 E164809_2_002
Figure4.3: The minispec LF110 Analyzer
4.3 Movable Working Table (Cart)
In order to ensure a safe and comfortable operation, the system is placed and slip-resistant
screwed on a movable working table – or so-called cart. The cart is standard with the
shipment of all minispec LF-systems. As special feature: There is a larger cart upgrade
available for minispec LF90II and LF110.
During the installation the Bruker Service representative will assemble this cart.