cytiva PRT-DPM-3T User manual

MidJet pressure
display unit
Instructions for use
cytiva.com

Table of Contents
1 Introduction ......................................................................................................................................... 3
2 Pressure display unit ........................................................................................................................... 6
3 Setup and operation ............................................................................................................................ 8
4 Maintenance and calibration .............................................................................................................. 12
5 Specifications ...................................................................................................................................... 15
6 Parts and accessories .......................................................................................................................... 16
Index ............................................................................................................................................................ 18
Table of Contents
2 MidJet pressure display unit Instructions for use 18117465 AD

1 Introduction
About this user guide
This user guide describes how to use the CytivaMidJet pressure display unit PRT-DPM-3T. Topics
include a product description, assembly instructions, operation instructions, and maintenance
procedures.
Audience
This user guide addresses the needs of scientists, process engineers, and technicians who operate
laboratory-scale cross-flow systems. The level of information presented in this guide assumes the
user possesses basic laboratory and technical skills, and has the knowledge and documentation to
safely operate any user supplied equipment connected to the pressure display unit. If you need assis-
tance with the instructions in this guide, contact Cytiva for more information.
Where to find more information
You can download technical documents and learn more about Cytiva cross-flow systems by visiting
our website, cytiva.com.
Safety
Anyone who works with the pressure display unit should read, understand, and follow the instruc-
tions in this user guide. If any operator does not understand an instruction, they should stop working
with the pressure display unit and contact Cytiva for guidance. You should save these instructions
and make them available to all users of the pressure display unit.
Cytiva designed the pressure display unit for displaying the pressure readings from pressure trans-
ducers installed into laboratory-scale, cross-flow filtration systems under the conditions stated in
this user guide. If you use the pressure display unit and pressure transducers in a manner not speci-
fied by Cytiva, you may impair the protection provided by the pressure display unit and pressure
transducers.
When using any laboratory equipment, the potential exists for personal injury unless you follow
established safety procedures. When installing and using Cytiva cross-flow systems, you should
follow good engineering practices as well as OSHA, federal, state, local, and your company’s safety
regulations and codes. You should follow your company’s safety regulations and the specific safety
instructions provided in this user guide.
Only qualified personnel who are adequately trained and who understand the operating instructions
should install, operate, maintain, and inspect the pressure display unit.
1 Introduction
MidJet pressure display unit Instructions for use 18117465 AD 3

Warnings, cautions, and tips
This user guide uses symbols and blocks of text to provide you with safety warnings and other impor-
tant information:
WARNING
WARNING indicates a hazardous situation which, if not avoided,
could result in death or serious injury. It is important not to proceed
until all stated conditions are met and clearly understood.
CAUTION
CAUTION indicates a hazardous situation which, if not avoided,
could result in minor or moderate injury. It is important not to
proceed until all stated conditions are met and clearly understood.
Tip: A tip contains useful information that can improve or optimize your procedures.
WARNING
If a pressure transducer leaks, it can release potentially hazardous
process or cleaning fluids and cause bodily harm. To prevent leaks
and the release of potentially hazardous fluids, limit system pres-
sure to 2 barg (30 psig), periodically check pressure transducer
connections for proper assembly and wear. Isolate and depressu-
rize your system before installing, removing, and checking pressure
transducers. Wear the appropriate personal protection devices and
clothing when operating and cleaning the system.
WARNING
Mishandling potentially hazardous process and cleaning solutions
can cause bodily harm. To safely handle potentially hazardous
process, cleaning, and storage solutions, read the material safety
data sheets for the solutions you use. Follow the material safety
data sheet instructions for safe handling and use the personal
protection equipment required by your company, and local, state,
and federal laws.
1 Introduction
4 MidJet pressure display unit Instructions for use 18117465 AD

WARNING
If you autoclave or use hot caustic cleaning solution (0.5 N NaOH) to
clean the pressure transducers, the transducers can fail causing
leaks of potentially hazardous cleaning or process fluid and bodily
harm. To avoid leaks of potentially hazardous solutions, do not
autoclave the pressure transducers. Limit exposure to caustic solu-
tion (0.5 N NaOH) to room temperature and only for short periods
(30 to 60 minutes) of time. Rinse all caustic thoroughly from the
transducers after exposure.
WARNING
If water or other liquids enter the pressure display unit, equipment
damage and electrical shock (bodily harm) can occur. Locate the
pressure display unit where it will not be exposed to water and
other fluids. Prevent water or other liquids from entering the unit.
Product labeling
The pressure display unit labeling, located on the back of the housing, provides key identification and
specification information (see the Figure below).
Figure 1.1: The PRT-DPM-3T pressure display unit labeling
1 Introduction
MidJet pressure display unit Instructions for use 18117465 AD 5

2 Pressure display unit
Package contents
Your pressure display unit arrives packaged in a cardboard box. The box includes these components:
Contents of PRT-DPM-3T
•display unit
•Three pressure transducers
•One temperature sensor
•Power cord (U.S.)
•User guide
•Certificates of compliance for pressure display unit
System overview
The PRT-DPM-3T pressure display unit includes three pressure displays and a temperature display
(see the Figure below).
Figure 2.1: The PRT-DPM-3T pressure display unit
Transducers
Each pressure display unit includes a set of pressure tranducers. Additional pressure transducers
can be purchased separately in packs of one or two.
The transducers use Luer-Lok™ connectors for connecting to your lab system tubing and an elec-
trical jack for connecting the electrical wire to the back of the pressure display unit.
2 Pressure display unit
6 MidJet pressure display unit Instructions for use 18117465 AD

WARNING
If you autoclave or use hot caustic cleaning solution (0.5 N NaOH) to
clean the pressure transducers, the transducers can fail causing
leaks of potentially hazardous cleaning or process fluid and bodily
harm. To avoid leaks of potentially hazardous solutions, do not
autoclave the pressure transducers. Limit exposure to caustic solu-
tion (0.5 N NaOH) to room temperature and only for short periods
(30 to 60 minutes) of time. Rinse all caustic solution thoroughly
from the transducers after exposure.
Thermocouple
The temperature signal is sent to the pressure display using a J-type thermocouple set in a
maleLuer-Lok fitting. The 5-foot length of signal wire ends in a standard 2-pin plug that plugs into the
back of the display unit. The thermocouple is calibrated by the manufacturer for digital displays.
The LED temperature display indicates temperature in °C.
2 Pressure display unit
MidJet pressure display unit Instructions for use 18117465 AD 7

3 Setup and operation
To setup your system you must integrate the pressure transducers in to your cross-flow system and
connect the transducer signal cables to the back of the pressure display unit.
Typical transducer placement in a cross-flow
filtration system
Monitoring the feed and retentate pressure—and sometimes the permeate pressure—enables the
safe and precise control of a cross-flow filtration system. Therefore, pressure transducers are
mounted on the feed and retentate lines (Fig. 3.1, on page 9). For cross-flow systems that can
benefit from monitoring the permeate pressure, a third pressure transducer (model PRT-DPM-3T)
can be mounted on the permeate line.
Temperature probe (thermocouple)
Monitoring the temperature in the reservoir or permeate collection vessel can be helpful. Pressure
display unit PRT-DPM-3T includes a temperature probe and LED temperature display that indicates
the temperature in °C.
CAUTION
If you overtighten the locking nut when installing transducers using
Luer-Lok connectors, you can damage the transducer. Often the
damage occurs when trying to loosen an overtightened connec-
tion. When you join the male and female components of a Luer-Lok,
a tight connection is essentially made. Rotating the nut prevents
the components from coming apart—it does not make the connec-
tion tighter. To prevent damaging pressure transducers, use only
light fingertip pressure to tighten the Luer-Lok’s rotating nut.
3 Setup and operation
8 MidJet pressure display unit Instructions for use 18117465 AD

Clamp
Tubing Pinch
Retentate
Feed
Temperature
Probe
Feed
Reservoir
Pump
Transducer
Signal
Pressure Display Unit
Cable
Blanked Off
Cross-Flow
Permeate Port
Cartridge
Line
Permeate
Collection
Permeate
Vessel
Figure 3.1: Typical transducer placement in a cross-flow system
Installing the transducers
CAUTION
The pressure display unit is calibrated at the factory with the
installed transducers. If you swap the transducers by plugging
them into different terminals on the back of the pressure display
unit, the accuracy of the pressure reading will be compromised. To
maintain the accuracy of the pressure display unit, do not swap the
transducers by plugging them into different terminals on the back
of the pressure display unit. Recalibrate the pressure display unit
when you install new pressure transducers.
Connect pressure transducers to the feed, retentate, and one of the permeate ports of your cross-
flow cartridge. Connect the transducer signal cables to the appropriate jacks—Inlet (or feed), Outlet
(or retentate and Permeate—on the back of the display unit. Plug the temperature sensor signal
cable into the jack on the back of the display unit. Place the temperature probe in the feed reservoir,
permeate collection vessel, or integrate it into the retentate line using a tee adaptor andLuer-Lok
connectors.
3 Setup and operation
MidJet pressure display unit Instructions for use 18117465 AD 9

WARNING
If a pressure transducer leaks, it can release potentially hazardous
process or cleaning fluids and cause bodily harm. To prevent leaks
and the release of potentially hazardous fluids, limit system pres-
sure to 2 barg (30 psig), periodically check pressure transducer
connections for proper assembly and wear. Isolate and depressu-
rize your system before installing, removing, and checking pressure
transducers. Wear the appropriate personal protection devices and
clothing when operating and cleaning the system.
Figure 3.2: A MidJet system and a pressure and temperature display unit
Powering up the display
Connect the pressure display unit power cord to a fuse-protected, electrical outlet of the proper
voltage (110 to 220 VAC, 50 to 60 Hz).
If you need to order a power cord for use outside the United States and Canada, see the part list in
Ordering parts, on page 16.
After making all the connections, power up the pressure display unit using the On/Off switch located
on the back panel of the unit.
3 Setup and operation
10 MidJet pressure display unit Instructions for use 18117465 AD