Fluke Biomedical MPS450 Operators User manual

PN 2243350
June 2010, Rev. 1
© 2010 Fluke Corporation. All rights reserved. Printed in USA. Specifications are subject to change without notice.
All product names are trademarks of their respective companies.
MPS450
Multiparameter Simulator
Operators Manual

Warranty and Product Support
Fluke Biomedical warrants this instrument against defects in materials and workmanship
for one year from the date of original purchase OR two years if at the end of your first
year you send the instrument to a Fluke Biomedical service center for calibration. You
will be charged our customary fee for such calibration. During the warranty period, we
will repair or at our option replace, at no charge, a product that proves to be defective,
provided you return the product, shipping prepaid, to Fluke Biomedical. This warranty
covers the original purchaser only and is not transferable. The warranty does not apply if
the product has been damaged by accident or misuse or has been serviced or modified by
anyone other than an authorized Fluke Biomedical service facility. NO OTHER
WARRANTIES, SUCH AS FITNESS FOR A PARTICULAR PURPOSE, ARE
EXPRESSED OR IMPLIED. FLUKE SHALL NOT BE LIABLE FOR ANY SPECIAL,
INDIRECT, INCIDENTAL OR CONSEQUENTIAL DAMAGES OR LOSSES,
INCLUDING LOSS OF DATA, ARISING FROM ANY CAUSE OR THEORY.
This warranty covers only serialized products and their accessory items that bear a
distinct serial number tag. Recalibration of instruments is not covered under the warranty.
This warranty gives you specific legal rights and you may also have other rights that vary
in different jurisdictions. Since some jurisdictions do not allow the exclusion or limitation
of an implied warranty or of incidental or consequential damages, this limitation of
liability may not apply to you. If any provision of this warranty is held invalid or
unenforceable by a court or other decision-maker of competent jurisdiction, such holding
will not affect the validity or enforceability of any other provision.
07/07

Contents (continued)
Notices
All Rights Reserved
Copyright 2010, Fluke Biomedical. No part of this publication may be reproduced, transmitted, transcribed, stored in a retrieval
system, or translated into any language without the written permission of Fluke Biomedical.
Copyright Release
Fluke Biomedical agrees to a limited copyright release that allows you to reproduce manuals and other printed materials for use in
service training programs and other technical publications. If you would like other reproductions or distributions, submit a written
request to Fluke Biomedical.
Unpacking and Inspection
Follow standard receiving practices upon receipt of the instrument. Check the shipping carton for damage. If damage is found, stop
unpacking the instrument. Notify the carrier and ask for an agent to be present while the instrument is unpacked. There are no special
unpacking instructions, but be careful not to damage the instrument when unpacking it. Inspect the instrument for physical damage such
as bent or broken parts, dents, or scratches.
Technical Support
For application support or answers to technical questions, either email [email protected] or call 1-800- 850-4608 ext
2560 or 1-440-498-2560.
Claims
Our routine method of shipment is via common carrier, FOB origin. Upon delivery, if physical damage is found, retain all packing
materials in their original condition and contact the carrier immediately to file a claim. If the instrument is delivered in good physical
condition but does not operate within specifications, or if there are any other problems not caused by shipping damage, please contact
Fluke Biomedical or your local sales representative.
Standard Terms and Conditions
Refunds and Credits
Please note that only serialized products and their accessory items (i.e., products and items bearing a distinct serial number
tag) are eligible for partial refund and/or credit. Nonserialized parts and accessory items (e.g., cables, carrying cases,
auxiliary modules, etc.) are not eligible for return or refund. Only products returned within 90 days from the date of original
purchase are eligible for refund/credit. In order to receive a partial refund/credit of a product purchase price on a serialized product, the
product must not have been damaged by the customer or by the carrier chosen by the customer to return the goods, and the product
must be returned complete (meaning with all manuals, cables, accessories, etc.) and in “as new” and resalable condition. Products not
returned within 90 days of purchase, or products which are not in “as new” and resalable condition, are not eligible for credit return and
will be returned to the customer. The Return Procedure (see below) must be followed to assure prompt refund/credit.
Restocking Charges
Products returned within 30 days of original purchase are subject to a minimum restocking fee of 15 %. Products returned in excess of
30 days after purchase, but prior to 90 days, are subject to a minimum restocking fee of 20 %. Additional charges for damage and/or
missing parts and accessories will be applied to all returns.
Return Procedure
All items being returned (including all warranty-claim shipments) must be sent freight-prepaid to our factory location. When you return
an instrument to Fluke Biomedical, we recommend using United Parcel Service, Federal Express, or Air Parcel Post. We also
recommend that you insure your shipment for its actual replacement cost. Fluke Biomedical will not be responsible for lost shipments
or instruments that are received in damaged condition due to improper packaging or handling.
Use the original carton and packaging material for shipment. If they are not available, we recommend the following guide for
repackaging:
Use a double-walled carton of sufficient strength for the weight being shipped.
Use heavy paper or cardboard to protect all instrument surfaces. Use nonabrasive material around all projecting parts.
Use at least four inches of tightly packed, industry-approved, shock-absorbent material around the instrument.
Returns for partial refund/credit:
Every product returned for refund/credit must be accompanied by a Return Material Authorization (RMA) number, obtained from our
Order Entry Group at 1-800- 850-4608 ext 2560 or 1-440-498-2560.

Repair and calibration:
To find the nearest service center, go to www.flukebiomedical.com/service, or
In the U.S.A.:
Cleveland Calibration Lab
Tel: 1-800-850-4606
Everett Calibration Lab
Tel: 1-888-993-5853
In Europe, Middle East, and Africa:
Eindhoven Calibration Lab
Tel: +31-402-675300
In Asia:
Everett Calibration Lab
Tel: +425-446-6945
Certification
This instrument was thoroughly tested and inspected. It was found to meet Fluke Biomedical’s manufacturing specifications
when it was shipped from the factory. Calibration measurements are traceable to the National Institute of Standards and
Technology (NIST). Devices for which there are no NIST calibration standards are measured against in-house performance
standards using accepted test procedures.
WARNING
Unauthorized user modifications or application beyond the published specifications may result in electrical shock hazards or
improper operation. Fluke Biomedical will not be responsible for any injuries sustained due to unauthorized equipment
modifications.
Restrictions and Liabilities
Information in this document is subject to change and does not represent a commitment by Fluke Biomedical. Changes made
to the information in this document will be incorporated in new editions of the publication. No responsibility is assumed by
Fluke Biomedical for the use or reliability of software or equipment that is not supplied by Fluke Biomedical, or by its
affiliated dealers.
Manufacturing Location
The MPS450 Multiparameter Simulator is manufactured at Fluke Biomedical, 6920 Seaway Blvd., Everett, WA, U.S.A.
Applicable Testing Standards
Fluke Biomedical’s MPS450™Multiparameter Simulator (hereafter referred to as the
MPS450) has been tested by an independent laboratory and meets the requirements listed
here.
Safety Requirements
USA UL 61010-1 (2nd Edition). General requirements.
Canada CAN/CSA C22.2 No. 61010 (2nd Edition), Safety
requirements for electrical equipment for measurement,
control and laboratory use.
EC Directive 2006/95/EC IEC/EN 61010-1:2001 (2nd Edition), safety requirement for
electrical equipment for measurement, control, and
laboratory use.
Electromagnetic Interference and Susceptibility
EN 61326-1:2006 Emissions Class A and Immunity
FCC Class A
Warning: Changes of modifications to this unit not expressly approved by the

Contents (continued)
manufacturer could void the user’s authority to operate the equipment.
This equipment has been tested and found to comply with the limits for a Class A digital
device.
These limits are designed to provide reasonable protection against harmful interference
when the equipment is operated in a commercial environment. Like all similar
equipment, this equipment generates, uses, and can radiate radio frequency energy, and,
if not installed and used in accordance with the instruction manual, may cause harmful
interference to radio communications. Operation of this equipment in a residential area is
likely to cause interference, in which case the user will be required to correct the
interference at his/her own expense.
Canadian Department of Communications Class A
This digital apparatus does not exceed Class A limits for radio emissions from digital
apparatus set out in the Radio Interference Regulations of the Canadian Department of
Communications.
Le présent appareil numérique n’excède pas des bruits radioélectriques dépassant les
limites applicables des appareils numériques de la Class A prescrites dans le Règlement
sur le brouillage radioélectrique édicté par le ministère des Communications du Canada.
Based on the testing standards below,
this device bears the
mark.
EC Directive 2004/108/EC Electromagnetic Compatibility
Emissions – Class A
The system has been type tested by an independent, accredited testing laboratory and
found to meet the requirements of EN 61326-1:2006 for Radiated Emissions and Line
Conducted Emissions.
EN 61000-3-2 Harmonics Current Emissions
EN 61000-3-3 Voltage Fluctuations and Flicker
Immunity
The system has been type tested by an independent, accredited testing laboratory and
found to meet the requirements of EN 61326-1:2006 for immunity.
EN 61000-4-2 Electrostatic Discharge
EN 61000-4-3 RF Electromagnetic Fields
EN 61000-4-4 Fast Transient/Burst
EN 61000-4-5 Surge Immunity
EN 61000-4-6 RF Common Mode Disturbance
EN 61000-4-11 Voltage Dips, Short interruptions and AC Variations
EC Directive 2006/95/EC Low Voltage
User Safety
The system has been type tested by an independent testing laboratory and found to meet
the requirements of EC Directive 2006/95/EC for Low Voltage. Verification of
compliance was conducted to the limits and methods of the following
EN 61010-1 (2001)
Safety Requirements for Electrical Equipment for Measurement Control and Laboratory
Use, Part 1:General requirements” (IEC 61010-1:2001, Mod).


i
Table of Contents
Chapter Title Page
1 Introduction and Specifications......................................................... 1-1
Introduction........................................................................................................ 1-3
MPS450 Features............................................................................................... 1-3
MPS450 Package Contents................................................................................ 1-5
Standard Equipment ...................................................................................... 1-5
Standard Accessories..................................................................................... 1-5
Optional Accessories ..................................................................................... 1-5
Date of Manufacture .......................................................................................... 1-6
Unpacking the MPS450 ..................................................................................... 1-6
Storage and Maintenance................................................................................... 1-6
Powering Up the MPS450 ................................................................................. 1-7
Connection the MPS450 .................................................................................... 1-8
Using the MPS450 ............................................................................................. 1-9
Viewing Current MPS450 Parameters............................................................... 1-10
Setting the MPS450 View Angle....................................................................... 1-12
Navigation in the MPS450................................................................................. 1-13
General Specifications ....................................................................................... 1-14
Detailed Specifications ...................................................................................... 1-15
Normal-Sinus-Rhythm Waveform ................................................................ 1-15
Pacemaker Waveform ................................................................................... 1-15
Arrhythmia .................................................................................................... 1-15
ECG-Performance-Testing ............................................................................ 1-15
Respiration..................................................................................................... 1-16
Blood Pressure............................................................................................... 1-16
Temperature................................................................................................... 1-16
Cardiac Output............................................................................................... 1-17
Fetal / Maternal-ECG .................................................................................... 1-17
Computer Setup ............................................................................................. 1-17
2 Cardiac Functions ............................................................................... 2-1
Introduction........................................................................................................ 2-3
ECG Functions................................................................................................... 2-3
Normal Sinus Rhythm (NSR)........................................................................ 2-3
Adjusting the ECG Heart Rate ...................................................................... 2-3

MPS450
Operators Manual
ii
Adjusting the ECG Amplitude ...................................................................... 2-4
Adult and Pediatric ECG ............................................................................... 2-5
Adjusting the ST Segment............................................................................. 2-6
Simulating ECG Artifact ............................................................................... 2-7
Pacemaker Waveforms.................................................................................. 2-8
Adjusting Pacemaker–Spike Amplitude........................................................ 2-9
Adjusting Pacemaker–Spike Width............................................................... 2-9
Arrhythmia Functions ........................................................................................ 2-10
Atrial Fibrillation........................................................................................... 2-10
Atrial Flutter .................................................................................................. 2-11
Sinus Arrhythmia........................................................................................... 2-11
Missed Beat ................................................................................................... 2-12
Atrial Tachycardia (AT) ................................................................................ 2-12
Paroxysmal Atrial Tachycardia (PAT) .......................................................... 2-13
Nodal Rhythm ............................................................................................... 2-13
Supraventricular Tachycardia........................................................................ 2-13
Premature Atrial Contraction (PAC) ............................................................. 2-14
Premature Nodal Contraction (PNC)............................................................. 2-14
Premature Ventricular Contractions .............................................................. 2-15
Multifocal PVCS ........................................................................................... 2-16
PVCS: 6, 12, or 24 Per Minute...................................................................... 2-16
Frequent Multifocal PVCS ............................................................................ 2-17
Bigeminy and Trigeminy............................................................................... 2-17
Multiple PVCS: Paired PVCS; Run 5 PVCS; Run 11 PVCS........................ 2-18
Ventricular Tachycardia ................................................................................ 2-19
Ventricular Fibrillation.................................................................................. 2-19
Asystole (Cardiac Standstill)......................................................................... 2-20
Heart Block: First, Second, and Third Degree .............................................. 2-20
Bundle-Branch Block .................................................................................... 2-21
ECG Testing ...................................................................................................... 2-22
Running a Performance Wave....................................................................... 2-22
Adjusting Performance-Wave Amplitude ..................................................... 2-23
R-Wave Detection ......................................................................................... 2-24
Setting R-Wave Rate ..................................................................................... 2-24
Setting R-Wave Width .................................................................................. 2-25
Setting R-Wave Amplitude ........................................................................... 2-26
Blood Pressure Function.................................................................................... 2-27
Setting BP Sensitivity.................................................................................... 2-27
Zeroing BP Channels..................................................................................... 2-28
Setting Static-Pressure Levels ....................................................................... 2-29
Running a Dynamic Waveform..................................................................... 2-31
Adding Respiration Artifact to the BP Signal ............................................... 2-32
Simulating the Swan-Ganz Procedure........................................................... 2-34
Cardiac Output................................................................................................... 2-36
Setting Up For a Cardiac-Output Test........................................................... 2-36
Simulating a Cardiac-Output Test ................................................................. 2-37
Injectate Failure and Left-To-Right Shunt .................................................... 2-37
Simulating Output From a Calibrated Pulse Signal....................................... 2-38
Fetal / Maternal ECG (Option) .......................................................................... 2-39
Simulating a Fixed Fetal Heart Rate (Fhr) .................................................... 2-39
Simulating a Periodic FHR With Intrauterine Pressure (IUP)....................... 2-40
3 Other Functions................................................................................... 3-1
Introduction........................................................................................................ 3-3
Respiration ......................................................................................................... 3-3

Contents (continued)
iii
Setting the Respiration Lead and Baseline .................................................... 3-3
Adjusting the Respiration Rate...................................................................... 3-4
Adjusting the Respiration Amplitude (Impedance Variation)....................... 3-5
Simulating Apnea (Respiration Standstill).................................................... 3-6
Temperature (Adjusting Body Temperature)..................................................... 3-6
4 Remote Operations ............................................................................. 4-1
Introduction........................................................................................................ 4-3
Remote Connection............................................................................................ 4-3
Entering Remote Commands ............................................................................. 4-3
Using Remote Entry to Operate In Numeric-Control Mode.............................. 4-4
General Remote Commands .............................................................................. 4-4
Error Messages .................................................................................................. 4-4
Codes and Actions ............................................................................................. 4-4
ECG Functions .............................................................................................. 4-5
Normal-Sinus ECG ................................................................................... 4-5
ECG Amplitude......................................................................................... 4-5
Adult / Pediatric ........................................................................................ 4-6
STE Elevation ........................................................................................... 4-6
ECG Artifact Stimulation.......................................................................... 4-7
Pacemaker Waveform ............................................................................... 4-8
Pacemaker Amplitude ............................................................................... 4-8
Pacemaker Width ...................................................................................... 4-8
Arrhythmia Functions.................................................................................... 4-9
Supraventricular Arrhythmia .................................................................... 4-9
Premature Arrhythmia............................................................................... 4-9
Ventricular Arrhythmia............................................................................. 4-10
Conduction Defect .................................................................................... 4-10
ECG Testing .................................................................................................. 4-10
Performance Waves .................................................................................. 4-11
Performance Wave Amplitude.................................................................. 4-11
R-Wave Rate ............................................................................................. 4-12
R-Wave Width .......................................................................................... 4-12
R-Wave Amplitude ................................................................................... 4-13
Respiration Functions.................................................................................... 4-14
Respiration Lead ....................................................................................... 4-14
Respiration Baseline (Impedance) ............................................................ 4-14
Respiration Rate ........................................................................................ 4-15
Respiration Amplitude .............................................................................. 4-15
Apnea Simulation...................................................................................... 4-16
Blood Pressure Functions .............................................................................. 4-16
Blood-Pressure Sensitivity ........................................................................ 4-16
Blood Pressure Zeroing............................................................................. 4-16
BP Channel 1: Static-Pressure Levels....................................................... 4-16
BP Channel 2: Static-Pressure Levels....................................................... 4-17
BP Channel 3: Static-Pressure Levels....................................................... 4-17
BP Channel 4: Static-Pressure Levels....................................................... 4-18
BP Channel 1: Dynamic Waveforms ........................................................ 4-18
BP Channel 2: Dynamic Waveforms ........................................................ 4-18
BP Channel 3: Dynamic Waveforms ........................................................ 4-19
BP Channel 4: Dynamic Waveforms ........................................................ 4-20
BP Channel 1: Respiration Artifact........................................................... 4-20
BP Channel 2: Respiration Artifact........................................................... 4-21
BP Channel 3: Respiration Artifact........................................................... 4-21
BP Channel 4: Respiration Artifact........................................................... 4-21

MPS450
Operators Manual
iv
Other Functions ............................................................................................. 4-21
Temperature .............................................................................................. 4-21
Cardiac-Output Wave / Injectate............................................................... 4-22
FHR Rate (Fixed)...................................................................................... 4-22
Intrauterine-Pressure (-) Wave .................................................................. 4-23
Intrauterine-Pressure (IUP) Period............................................................ 4-23
View Angle ............................................................................................... 4-23
Beeper ....................................................................................................... 4-24
Appendices
A Troubleshooting .......................................................................................... A-1
B Glossary....................................................................................................... B-1

v
List of Tables
Table Title Page
1-1. MPS450 Functions ................................................................................................. 1-3
1-2. ECG Jack Labeling ................................................................................................ 1-8
1-3. MPS450 Button Description .................................................................................. 1-9
1-4. Parameter Viewing List.......................................................................................... 1-11
2-1. Numeric Codes for BPM Settings.......................................................................... 2-4
2-2. Numeric Codes for ECG Amplitude Settings ........................................................ 2-5
2-3. Numeric Codes for Patient-Type Settings.............................................................. 2-6
2-4. Numeric Code for ST-Segment Settings................................................................ 2-6
2-5. Numeric Code for ECG Artifact Settings .............................................................. 2-8
2-6. Numeric Code for Pacemaker-Waveform Settings ................................................ 2-9
2-7. Numeric Codes for Pacemaker-Amplitude Settings .............................................. 2-9
2-8. Numeric Codes for Pacemaker-Width Settings...................................................... 2-10
2-9. Numeric Codes for Atrial-Fibrillation-Amplitude Settings ................................... 2-11
2-10. Numeric Codes for PVC-Waveform Settings ........................................................ 2-16
2-11. Numeric Codes for PVCs-Per-Minute Settings...................................................... 2-17
2-12. Numeric Codes for PVC-Sequence Settings.......................................................... 2-18
2-13. Numeric Codes for Multiple-PVC Settings ........................................................... 2-19
2-14. Numeric Codes for Ventricular-Fibrillation-Amplitude Settings........................... 2-20
2-15. Numeric Code for Heart-Block Settings ................................................................ 2-21
2-16. Numeric Code for Bundle Branch-Block Settings................................................. 2-22
2-17. Numeric Codes for Wave/Rate Settings................................................................. 2-23
2-18. Numeric Code for Wave Amplitude Settings......................................................... 2-23
2-19. Numeric Codes for R-Wave-Rate Settings ............................................................ 2-25
2-20. Numeric Code R-Wave Width Settings ................................................................. 2-25
2-21. Numeric Codes for R-Wave-Amplitude Settings................................................... 2-26
2-22. Numeric Codes for BP-Sensitivity Settings ........................................................... 2-28
2-23. Numeric Codes for Static-Pressure-Level Settings ................................................ 2-30
2-24. Dynamic Waveform Availability by BP Channel.................................................. 2-31
2-25. Numeric Codes for Dynamic-Wave Settings ......................................................... 2-32
2-26. Numeric Codes for Respiration-Artifact Settings .................................................. 2-33
2-27. Numeric Codes for Swan-Ganz-Simulation Settings............................................. 2-35
2-28. Cardiac-Output Monitor Settings........................................................................... 2-36
2-29. Numeric Codes for Temperature/Flow Settings..................................................... 2-37
2-30. Numeric Code for Condition/Temperature Setting ................................................ 2-38
2-31. Numeric Code for Calibration Setting ................................................................... 2-39

MPS450
Operators Manual
vi
2-32. Numeric Codes for Heart-Rate Settings................................................................. 2-40
2-33. Numeric Codes for IUP Wave Settings.................................................................. 2-41
2-34. Numeric Codes for IUP Contraction Period Settings............................................. 2-41
3-1. Numeric Codes for Respiration-Lead Settings....................................................... 3-4
3-2. Numeric Codes for Respiration-Baseline Settings................................................. 3-4
3-3. Numeric Codes for Respiration-Rate Settings ....................................................... 3-5
3-4. Numeric Codes for Respiration-Amplitude Settings.............................................. 3-5
3-5. Numeric Codes for Apnea Simulation Settings ..................................................... 3-6
3-6. Numeric Codes for Temperature-Celsius Settings................................................. 3-7
4-1. Remote Connector Signal Pin-Out......................................................................... 4-3
4-2. General Remote Commands................................................................................... 4-4
4-3. Numeric Codes for Normal Sinus ECG Actions.................................................... 4-5
4-4. Numeric Codes for ECG Amplitude Actions......................................................... 4-5
4-5. Numeric Codes for Adult / Pediatric Actions ........................................................ 4-6
4-6. Numeric Codes for STE Elevation Actions ........................................................... 4-6
4-7. Numeric Codes for ECG Artifact Stimulation Actions.......................................... 4-7
4-8. Numeric Codes for Pacemaker Waveform Actions ............................................... 4-8
4-9. Numeric Codes for Pacemaker Amplitude Actions ............................................... 4-8
4-10. Numeric Codes for Pacemaker Width Actions ...................................................... 4-8
4-11. Numeric Codes for Supraventricular Arrhythmia Actions..................................... 4-9
4-12. Numeric Codes for Premature Arrhythmia Actions............................................... 4-9
4-13. Numeric Codes for Ventricular Arrhythmia Actions ............................................. 4-10
4-14. Numeric Codes for Conduction Defect Actions..................................................... 4-10
4-15. Numeric Codes for Performance Waves Actions................................................... 4-11
4-16. Numeric Codes for Performance Wave Amplitude Actions .................................. 4-11
4-17. Numeric Codes for R-Wave Rate Actions ............................................................. 4-12
4-18. Numeric Codes for R-Wave Width Actions .......................................................... 4-12
4-19. Numeric Codes for R-Wave Amplitude Actions ................................................... 4-13
4-20. Numeric Codes for Respiration Lead Actions ....................................................... 4-14
4-21. Numeric Codes for Respiration Baseline (Impedance) Actions............................. 4-14
4-22. Numeric Codes for Respiration Rate Actions ........................................................ 4-15
4-23. Numeric Codes for Respiration Amplitude Actions .............................................. 4-15
4-24. Numeric Codes for Apnea Simulation Actions...................................................... 4-16
4-25. Numeric Codes for Blood-Pressure Sensitivity Actions ........................................ 4-16
4-26. Numeric Codes for Blood-Pressure Zeroing Actions............................................. 4-16
4-27. Numeric Codes for BP Channel 1: Static-Pressure Levels Actions ....................... 4-17
4-28. Numeric Codes for BP Channel 2: Static-Pressure Levels Actions ....................... 4-17
4-29. Numeric Codes for BP Channel 3: Static-Pressure Levels Actions ....................... 4-17
4-30. Numeric Codes for BP Channel 4: Static-Pressure Levels Actions ....................... 4-18
4-31. Numeric Codes for BP Channel 1: Dynamic Waveforms Actions ........................ 4-18
4-32. Numeric Codes for BP Channel 2: Dynamic Waveforms Actions ........................ 4-19
4-33. Numeric Codes for BP Channel 3: Dynamic Waveforms Actions ........................ 4-19
4-34. Numeric Codes for BP Channel 4: Dynamic Waveforms Actions ........................ 4-20
4-35. Numeric Codes for BP Channel 1: Respiration Artifact Actions........................... 4-20
4-36. Numeric Codes for BP Channel 2: Respiration Artifact Actions........................... 4-21
4-37. Numeric Codes for BP Channel 3: Respiration Artifact Actions........................... 4-21
4-38. Numeric Codes for BP Channel 4: Respiration Artifact Actions........................... 4-21
4-39. Numeric Codes for Temperature Actions .............................................................. 4-21
4-40. Numeric Codes for Cardiac-Output Wave / Injectate Actions............................... 4-22
4-41. Numeric Codes for FHR Rate (Fixed) Actions...................................................... 4-22
4-42. Numeric Codes for Intrauterine-Pressure (-) Wave Actions .................................. 4-23
4-43. Numeric Codes for Intrauterine-Pressure (IUP) Period Actions............................ 4-23
4-44. Numeric Codes for View Angle Actions ............................................................... 4-23
4-45. Numeric Codes for Beeper Actions ....................................................................... 4-24

Contents (continued)
vii
List of Figures
Figure Title Page
1-1. MPS450 Patient Simulator..................................................................................... 1-8

MPS450
Operators Manual
viii

1-1
Chapter 1
Introduction and Specifications
Title Page
Introduction.......................................................................................................... 1-3
MPS450 Features................................................................................................. 1-3
MPS450 Package Contents.................................................................................. 1-5
Standard Equipment ........................................................................................ 1-5
Standard Accessories....................................................................................... 1-5
Optional Accessories ....................................................................................... 1-5
Date of Manufacture ............................................................................................ 1-6
Unpacking the MPS450 ....................................................................................... 1-6
Storage and Maintenance..................................................................................... 1-6
Powering Up the MPS450 ................................................................................... 1-7
Connection the MPS450 ...................................................................................... 1-8
Using the MPS450 ............................................................................................... 1-9
Viewing Current MPS450 Parameters................................................................. 1-10
Setting the MPS450 View Angle......................................................................... 1-12
Navigation in the MPS450................................................................................... 1-13
General Specifications ......................................................................................... 1-14
Detailed Specifications ........................................................................................ 1-15
Normal-Sinus-Rhythm Waveform .................................................................. 1-15
Pacemaker Waveform ..................................................................................... 1-15
Arrhythmia ...................................................................................................... 1-15
ECG-Performance-Testing .............................................................................. 1-15
Respiration....................................................................................................... 1-16
Blood Pressure................................................................................................. 1-16
Temperature..................................................................................................... 1-16
Cardiac Output................................................................................................. 1-17
Fetal / Maternal-ECG ...................................................................................... 1-17
Computer Setup ............................................................................................... 1-17


Introduction and Specifications
Introduction 1
1-3
Introduction
Fluke Biomedical's MPS450 Multiparameter Simulator (hereafter referred to as the
MPS450) provides a basis to train, evaluate, and perform preventive maintenance for
virtually all patient monitors found in the healthcare industry. This is accomplished with
multiple physiological simulations for ECG, blood pressure, respiration, temperature,
pacemaker, artifact, and arrhythmia conditions. The MPS450 is a lightweight, battery-
powered unit that is portable enough to test a patient monitor anywhere the monitor is
being used.
The microprocessor control of the MPS450, combined with extensive digital memory,
assures rapid test and verification of cardiac-monitoring medical equipment. All
simulation settings are read easily on the clear, built-in LCD (liquid crystal display), with
adjustable viewing “angle” (contrast). Tests and simulations can be selected quickly and
easily, by choosing menu selections, by using front-panel keys to enter numeric codes for
actions, or by using computer control.
A cross-referenced listing of MPS450 actions, numeric codes, and remote-entry
commands is available in Chapter 4: “Remote Operations.”
MPS450 Features
The MPS450 provides control over the widest array of testing parameters, while also
providing simplicity in design and user interface. A keypad enables the easy entry of
functions, parameters, and codes; easy-access jacks simplify quick connection to
monitoring devices.
The wide variety of abnormal ECG waveforms replicated by the MPS450 can be used not
only for testing arrhythmia-detection systems, but also for training medical personnel,
hospital administrators, and staff. The MPS450 can be used to teach techniques for
recognizing normal and abnormal conditions in the heart, lungs, and circulatory system,
as well as techniques for CPR and defibrillation/cardioversion. Cardiac physiologists can
learn how to interpret ECG waveforms; respiratory physiologists can learn
pulmonary/respiratory analysis techniques.
The groupings in Table 1-1 list the main categories of MPS450 functions. Each of these
function groupings is explained in a corresponding section.
Table 1-1. MPS450 Functions
Function Category Function Description
Normal sinus rhythm
ECG rate and amplitude
Adult / pediatric QRS
ST-segment elevation
ECG-artifact simulation
Pacemaker waveforms
ECG Functions
Pacer amplitude and
width
The MPS450 provides complete 3-, 5-, and
12-lead ECG simulation that includes seven
artificial pacemaker conditions. Normal sinus
rhythm is output over a range of heart rates
and voltage amplitudes.
ST-segment elevation is adjustable.

MPS450
Operators Manual
1-4
Table 1-1. MPS450 Functions (cont.)
Function Category Function Description
Supraventricular
arrhythmia
Premature arrhythmia
Missed beat
Ventricular arrhythmia
Arrhythmia Functions
Conduction defect
The MPS450 simulates 36 types of
arrhythmias, such as systole PVCs, systole,
systole, tachycardia, fibrillation, flutter, and
systole. Simulated conduction defects include
first-, second-, and third-degree heart block;
and left- and right-bundle-branch block.
Square/pulse/triangle/sine
R waveforms
Wave amplitude
ECG-Performance Testing
R-wave rate and width
The MPS450 generates square, pulse,
triangle, sine, and R waveforms for
performance testing. Wave amplitude is
adjustable, as well as R-wave rate and width.
Respiration lead
Baseline (impedance)
Respiration rate
Respiration amplitude
Respiration
Apnea simulation
Calibrated respiration rates are generated
from 15 to 120 BrPM (breaths per minute),
including four respiration-impedance
selections, with two different lead selections
(LA or LL). The output-impedance level is
adjustable to 500, 1000, 1500, or 2000 ohms.
The MPS450 generates apnea pauses (0
BrPM) of 12, 22, and 32 seconds, as well as a
continuous-apnea condition.
BP sensitivity
BP zeroing
Static-pressure levels
Dynamic BP waveforms
BP respiration artifact
Blood Pressure
Swan-Ganz simulation
The MPS450 simulates static and dynamic
invasive pressures, providing complete blood-
pressure simulation. The MPS450 also
provides calibrated static pressures and
dynamic waveforms to simulate signals such
as pulmonary-artery, left- and right-ventricle
and Swan Ganz (RA-RV-PA-PAW) pressures.
Temperature Temperature settings The MPS450 provides four preset
temperature simulations: 0 °C, 24 °C, 37 °C,
and 40 °C. All temperature simulations are
compatible with Yellow Springs, Inc. (YSI)
Series 400 and 700 thermistors.
Injectate temperature
Injectate flow
Faulty-injectate curve
Left-to-right-shunt curve
Cardiac Output (Option)
Calibrated pulse
The MPS450 simulates cardiac-output
waveforms for testing the accuracy and
sensitivity of cardiac-output computational
devices equipped with Baxter-Edwards-type
catheters. Injectate temperature can be set
either to “iced” or room-temperature
conditions, with adjustable flow rate (in liters
per minute). The MPS450 also simulates a
faulty-injectate curve, as well as a left-to-right-
shunt curve.

Introduction and Specifications
MPS450 Package Contents 1
1-5
Table 1-1. MPS450 Functions (cont.)
Function Category Function Description
Fixed/periodic FHRFetal / Maternal ECG
(Option) IUP simulation
The MPS450 simulates a combined fetal and
maternal ECG occurring during labor, as well
as a selection of pressure waveforms
produced by uterine contractions. The
contraction period is adjustable and includes a
manually generated waveform.
RS-232 serial portRemote Operations
RS-232 serial port
MPS450 features include a built-in RS-232
serial port that, when connected to a
computer, enables instrument control through
remote commands. In addition, a special
command can be used to operate the
MPS450 remotely in the numeric-control
mode.
Warning
To prevent personal injury, use the Simulator in the manner
specified in this manual or the protection provided by the
Simulator may be impaired.
MPS450 Package Contents
Standard Equipment
•MPS450 Multiparameter Simulator
Standard Accessories
•MPS450 Operators Manual (P/N 2243350)
•Registration card
•Two 9-volt alkaline batteries (minimum 8 hours continuous use)
•Cardiac-output adapter box (P/N 2226608, standard with Cardiac-Output Option)
Optional Accessories
•Carrying case (P/N 2248623)
•Blood-pressure cables (See your local Fluke Biomedical Representative for
availability)
•Temperature cables (YSI 400 Series: P/N 2391976; 700 Series: P/N 2391983)
•High-level-output cable (P/N 2226958)
•Universal injectate-temperature adapter (P/N 2226800)
•RS-232 cable (P/N 2238659)
•Service Manual (P/N 2243361)
•Battery eliminator (P/N 2720054)
•Contains universal power supply, 9 - 264V, USA, AUS, DEN, IND, ISR,
ITAL, SHK, SWZ and UK
•For power cord order 284174 (USA), 658641 (AUS), 2200218 (DEN),
2200229 (IND), 2200241 (ISR), 2198785 (ITAL), 769422 (SHK), 769448
(SWZ) and 769455 (UK)

MPS450
Operators Manual
1-6
Date of Manufacture
The date of manufacture of the MPS450 unit appears on a label on the back of the
instrument, for example, JAN-03.
Unpacking the MPS450
Unpack the MPS450 and accessories from the shipping carton and insert the batteries.
Inspect the unit carefully for damage, such as cracks, dents, scratches, or bent parts. If
any physical damage is apparent, please call Fluke Biomedical for assistance, and notify
the carrier if the damage appears to be the result of a shipping mishap.
Storage and Maintenance
As with most electronic equipment, the MPS450 should be operated in a dry area within
normal temperature limits (10 °C to 40 °C).
There are no unique storage requirements. However, when storing the unit, maintain the
storage temperature between -25 °C and 50 °C. Remove the batteries if the unit will be
stored for a long period.
The MPS450 should be recalibrated once a year by a qualified technician. For safety
reasons, although the power output from the MPS450 is not potentially dangerous, only
an experienced technician should open the unit to access the inner electronics.
The MPS450 operates continuously for 8 or more hours on two 9-volt alkaline batteries,
which should be replaced regularly. The message “Low Battery” displays on the LCD
whenever the batteries need to be replaced.
Note
When the LCD screen displays a message warning that batteries are low,
replace the two batteries immediately. The battery compartment is located
at the back of the unit, toward the bottom. Use only two new 9-volt
batteries.
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