GE UVis-920 User manual

Monitor UVis-920
Operating Instructions
Original instructions

Table of Contents
41 Introduction ..........................................................................................................
41.1 Prerequisites ...........................................................................................................................................
41.2 Important user information .............................................................................................................
61.3 Regulatory information ......................................................................................................................
71.3.1 EU Directives ....................................................................................................................................
71.3.2 Eurasian Customs Union ............................................................................................................
81.3.3 Regulations for USA and Canada ...........................................................................................
91.3.4 Other regulations and standards ............................................................................................
101.4 User documentation ...........................................................................................................................
112 Safety instructions ...............................................................................................
112.1 Safety precautions ...............................................................................................................................
152.2 Labels .........................................................................................................................................................
172.3 Emergency procedures ......................................................................................................................
172.4 Recycling information .........................................................................................................................
182.5 Declaration of Hazardous Substances (DoHS) ........................................................................
203 System description ..............................................................................................
203.1 Illustrations ..............................................................................................................................................
213.2 Monitor principle ...................................................................................................................................
233.3 Flow cell principle .................................................................................................................................
244 Installation ............................................................................................................
254.1 Unpacking ................................................................................................................................................
254.2 Site requirements ..................................................................................................................................
254.3 Transport ..................................................................................................................................................
264.4 Installing the cell holder .....................................................................................................................
264.5 Installing the flow cells .......................................................................................................................
334.6 Connecting electrical cables ...........................................................................................................
375 Operation ..............................................................................................................
385.1 Menu selection .......................................................................................................................................
385.1.1 Monitor UVis-920 front panel ...................................................................................................
395.1.2 Menu navigation ............................................................................................................................
425.2 Turning the monitor on and off ......................................................................................................
435.3 Main menu overview ...........................................................................................................................
435.4 Setting wavelength ..............................................................................................................................
445.5 Custom filters .........................................................................................................................................
455.6 Autozero ....................................................................................................................................................
455.7 Reading absorbance values ............................................................................................................
455.8 Setup menu .............................................................................................................................................
505.9 Check menu ............................................................................................................................................
525.10 UV cell calibration .................................................................................................................................
535.11 Changing flow cell ................................................................................................................................
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Table of Contents

535.12 Restart after power failure ...............................................................................................................
546 Maintenance .........................................................................................................
556.1 Cleaning before planned service ...................................................................................................
556.2 Cleaning the instrument housing ..................................................................................................
556.3 Cleaning the flow cell and optical connectors ........................................................................
576.4 Storage ......................................................................................................................................................
587 Troubleshooting ...................................................................................................
597.1 General ......................................................................................................................................................
597.2 Faults and actions ................................................................................................................................
607.3 Error messages ......................................................................................................................................
618 Reference information ........................................................................................
618.1 Technical specifications .....................................................................................................................
668.2 Health and Safety Declaration Form ...........................................................................................
688.3 Accessories and spare parts ...........................................................................................................
Monitor UVis-920 Operating Instructions 29055049 AD 3
Table of Contents

1 Introduction
Purpose of the Operating
Instructions
The Operating Instructions provides you with the instructions needed to handle Monitor
UVis-920 in a safe way.
1.1 Prerequisites
In order to operate Monitor UVis-920 safely, and according to the intended purpose, the
following prerequisites must be met:
•You should be acquainted with the use of bioprocessing equipment and with the
handling of biological materials.
•You must read and understand the Safety chapter of these Operating Instructions.
•The system must be installed according to the instructions in the Installation chapter.
About this chapter
This chapter contains important user information, a description of the intended use of
Monitor UVis-920, regulatory information, list of associated documentation, definitions
of safety notices, etc.
1.2 Important user information
Read this before operating the
product
All users must read the entire Operating Instructions before installing, operating or
maintaining the product.
Always keep the Operating Instructions at hand when operating the product.
4 Monitor UVis-920 Operating Instructions 29055049 AD
1 Introduction

Do not operate the product in any other way than described in the user documentation.
If you do, you may be exposed to hazards that can lead to personal injury and you may
cause damage to the equipment.
Intended use
Monitor UVis-920 is a UV and visible light absorption monitor for use in liquid chromatog-
raphy.
Monitor UVis-920 is intended for research use only, and shall not be used in any clinical
procedures, or for diagnostic purposes.
Safety notices
This user documentation contains safety notices (WARNING, CAUTION, and NOTICE)
concerning the safe use of the product. See definitions below.
WARNING
WARNING indicates a hazardous situation which, if not avoided,
could result in death or serious injury. It is important not to proceed
until all stated conditions are met and clearly understood.
CAUTION
CAUTION indicates a hazardous situation which, if not avoided,
could result in minor or moderate injury. It is important not to pro-
ceed until all stated conditions are met and clearly understood.
NOTICE
NOTICE indicates instructions that must be followed to avoid
damage to the product or other equipment.
Monitor UVis-920 Operating Instructions 29055049 AD 5
1 Introduction
1.2 Important user information

Notes and tips
A note is used to indicate information that is important for trouble-free and
optimal use of the product.
Note:
A tip contains useful information that can improve or optimize your procedures.
Tip:
Typographical conventions
Software items are identified in the text by bold italic text. A colon separates menu levels,
thus File:Open refers to the Open command in the File menu.
Hardware items are identified in the text by bold text (for example, Power).
1.3 Regulatory information
In this section
This section describes the directives and standards that are fulfilled by Monitor UVis-920.
Manufacturing information
The table below summarizes the required manufacturing information.
InformationRequirement
GE Healthcare Bio-Sciences AB,Name and address of manufacturer
Björkgatan 30, SE 751 84 Uppsala, Sweden
In this section
See pageSection
71.3.1 EU Directives
71.3.2 Eurasian Customs Union
81.3.3 Regulations for USA and Canada
91.3.4 Other regulations and standards
6 Monitor UVis-920 Operating Instructions 29055049 AD
1 Introduction
1.2 Important user information

1.3.1 EU Directives
Conformity with EU Directives
This product fulfills the European Directives listed below. See the EU Declaration of
Conformity for the directives and regulations that apply for the CE marking.
If not included with the product, a copy of the EU Declaration of Conformity is available
on request.
TitleDirective
Electromagnetic Compatibility (EMC) Directive2014/30/EU
Low Voltage Directive (LVD)2014/35/EU
Restriction of Hazardous Substances (RoHS) Directive2011/65/EU
CE marking
The CE marking and the corresponding EU Declaration of Conformity is valid for the in-
strument when it is:
•used according to the Operating Instructions or user manuals, and
•used in the same state as it was delivered from GE, except for alterations described
in the Operating Instructions or user manuals.
1.3.2 Eurasian Customs Union
Introduction
This section contains additional regulatory information to comply with the Eurasian
Customs Union technical regulations.
Monitor UVis-920 Operating Instructions 29055049 AD 7
1 Introduction
1.3 Regulatory information
1.3.1 EU Directives

Manufacturer and importer
information
The table below summarizes the manufacturer and importer information required by
the Eurasian Customs Union.
InformationRequirement
See Manufacturing informationName and address of manufacturer
Telephone: + 46 771 400 600Telephone number of manufacturer
GE Healthcare LLCImporter and/or company for obtain-
ing information about importer GE Healthcare Life Sciences
Presnenskaya nab., 10C, 12th floor
RU-123 317 Moscow, Russian Federation
Telephone 1: + 7 495 411 9714
Fax nr: + 7 495 739 6932
Email: [email protected]
1.3.3 Regulations for USA and Canada
FCC compliance
This device complies with part 15 of the FCC Rules. Operation is subject to the following
two conditions: (1) This device may not cause harmful interference, and (2) this device
must accept any interference received, including interference that may cause undesired
operation.
The user is cautioned that any changes or modifications not expressly approved
by GE could void the user’s authority to operate the equipment.
Note:
This equipment has been tested and found to comply with the limits for a Class B digital
device, pursuant to part 15 of the FCC Rules. These limits are designed to provide rea-
sonable protection against harmful interference in a residential installation. This equip-
ment generates, uses and can radiate radio frequency energy and, if not installed and
used in accordance with the instructions, may cause harmful interference to radio
communications. However, there is no guarantee that interference will not occur in a
particular installation. If this equipment does cause harmful interference to radio or
television reception, which can be determined by turning the equipment off and on, the
user is encouraged to try to correct the interference by one or more of the following
measures:
•Reorient or relocate the receiving antenna.
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1 Introduction
1.3 Regulatory information
1.3.2 Eurasian Customs Union

•Increase the separation between the equipment and receiver.
•Connect the equipment into an outlet on a circuit different from that to which the
receiver is connected.
•Consult the dealer or an experienced radio/TV technician for help.
CAN ICES/NMB compliance
This product complies with the Canadian standard ICES-001/NMB-001 concerning
electromagnetic compatibility.
1.3.4 Other regulations and standards
Introduction
This section describes the standards that apply to the Monitor UVis-920 system.
Environmental conformity
This product conforms to the following environmental requirements.
TitleRequirement
Waste Electrical and Electronic Equipment (WEEE) Directive2012/19/EU
Management Methods for the Restriction of the Use of Haz-
ardous Substances in Electrical and Electronic Products.
China RoHS
Standards, machinery and
electrical equipment
Standard requirements fulfilled by this product are summarized in the table below.
DescriptionStandard
Safety of machinery. General principles for design. Risk
assessment and risk reduction.
EN ISO 12100
Safety requirements for electrical equipment for mea-
surement, control, and laboratory use - Part 1: General
requirements.
EN 61010-1, IEC 61010-1,
UL 61010-1, CAN/CSA-
C22.2 No. 61010-1
Monitor UVis-920 Operating Instructions 29055049 AD 9
1 Introduction
1.3 Regulatory information
1.3.3 Regulations for USA and Canada

DescriptionStandard
Electrical Equipment for Measurement, Control, and
Laboratory Use-EMC requirements-Part 1: General re-
quirements
EN 61326-1
(Emission according to CISPR 11, Group 1, class A)
Industrial, Scientific and Medical (ISM) Radio Frequency
Generators (Canada)
ICES-001
1.4 User documentation
In addition to these Operating Instructions, the documentation package supplied with
Monitor UVis-920 also includes product documentation binders containing detailed
specifications and traceability documents.
The most important documents in the document package with regard to technical aspects
of Monitor UVis-920 are listed below.
System-specific documentation
ContentUser documentation
Detailed system description. Comprehensive user
instructions, method creation, operation, ad-
vanced maintenance and troubleshooting.
Monitor UVis-920 Operating
Instructions
Document whereby the manufacturer ensures
that the product satisfies and is in conformity with
the essential requirements of the applicable direc-
tives.
EU Declaration of Conformity for
Monitor UVis-920
10 Monitor UVis-920 Operating Instructions 29055049 AD
1 Introduction
1.3 Regulatory information
1.3.4 Other regulations and standards

2 Safety instructions
About this chapter
This chapter describes safety compliance, safety labels, general safety precautions,
emergency procedures, power failure and recycling of Monitor UVis-920.
In this chapter
This chapter contains the following sections:
See pageSection
112.1 Safety precautions
152.2 Labels
172.3 Emergency procedures
172.4 Recycling information
182.5 Declaration of Hazardous Substances (DoHS)
2.1 Safety precautions
General precautions
Always follow these General precautions to avoid injury when using the Monitor UVis-920
instrument.
WARNING
Do not operate the product in any other way than described in the
user documentation.
Monitor UVis-920 Operating Instructions 29055049 AD 11
2 Safety instructions

WARNING
Only properly trained personnel may operate and maintain the
product.
Personal protection
WARNING
Always use appropriate Personal Protective Equipment (PPE) during
operation and maintenance of this product.
WARNING
Hazardous substances and biological agents. When using haz-
ardous chemical and biological agents, take all suitable protective
measures, such as wearing protective clothing, glasses and gloves
resistant to the substances used. Follow local and/or national
regulations for safe operation and maintenance of Monitor
UVis-920.
WARNING
Spread of biological agents. The operator must take all necessary
actions to avoid spreading hazardous biological agents. The facility
must comply with the national code of practice for biosafety.
Installing and moving the
instrument
WARNING
High intensity UV light. This product uses high intensity ultra-violet
light. Do not disconnect the optical fibers while the lamp is on.
12 Monitor UVis-920 Operating Instructions 29055049 AD
2 Safety instructions
2.1 Safety precautions

WARNING
Protective ground. The product must always be connected to a
grounded power outlet.
WARNING
Power cord. Only use power cords with approved plugs delivered
or approved by GE.
WARNING
Access to power switch and power cord with plug. Do not block
access to the power switch and power cord. The power switch
must always be easy to access. The power cord with plug must
always be easy to disconnect.
CAUTION
Make sure that the system is placed on a stable, level bench with
adequate space for ventilation.
System operation
WARNING
If liquid is spilled on the equipment, the electrical power supply
must be disconnected immediately. The equipment must be com-
pletely dry on the inside and the outside before reconnecting the
power supply.
Monitor UVis-920 Operating Instructions 29055049 AD 13
2 Safety instructions
2.1 Safety precautions

Maintenance
WARNING
Electrical shock hazard. All repairs should be done by service
personnel authorized by GE. Do not open any covers or replace
parts unless specifically stated in the user documentation.
WARNING
Disconnect power. Always disconnect power from the instrument
before performing any maintenance task.
WARNING
Hazardous chemicals or biological agents. When using hazardous
chemicals or biological agents, make sure that the entire system
has been flushed thoroughly with bacteriostatic solution (e.g., NaOH)
and distilled water before service and maintenance.
WARNING
Use only approved parts. Only spare parts and accessories that
are approved or supplied by GE may be used for maintaining or
servicing the product.
WARNING
Corrosive substance. NaOH is corrosive and therefore dangerous
to health. When using hazardous chemicals, avoid spillage and
wear protective glasses and other suitable Personal Protective
Equipment (PPE).
CAUTION
Hazardous chemicals or biological agents in UV flow cell. Make
sure that the entire flow cell has been flushed thoroughly with
bacteriostatic solution (e.g., NaOH) and distilled water, before service
and maintenance.
14 Monitor UVis-920 Operating Instructions 29055049 AD
2 Safety instructions
2.1 Safety precautions

2.2 Labels
Introduction
This section describes the system label on Monitor UVis-920 and its meaning.
System label
The illustration below shows the system label.
The specific data shown on the system label below is only an example. Actual
data is specific for each individual system and may vary from system to system.
Note:
The system label information is explained in the table below.
DescriptionLabel text
GE code number.Code no:
GE serial number.Serial no:
Manufacturing year and monthMfg Year:
Voltage.Voltage:
Supply voltage frequency.Frequency:
Max power.Max power:
Warning! Read the user documentation before using
the system. Do not open any covers or replace parts
unless specifically stated in the user documentation.
Monitor UVis-920 Operating Instructions 29055049 AD 15
2 Safety instructions
2.2 Labels

DescriptionLabel text
This symbol indicates that waste electrical and electron-
ic equipment must not be disposed as unsorted munic-
ipal waste and must be collected separately. Please
contact an authorized representative of the manufac-
turer for information concerning the decommissioning
of equipment.
This symbol indicates that the product contains haz-
ardous materials in excess of the limits established by
the Chinese standard GB/T 26572-2011 Requirements
for Concentration Limits for Certain Hazardous Sub-
stances in Electronics.
The system complies with applicable European direc-
tives.
The system complies with the requirements for
electromagnetic compliance (EMC) in Australia and New
Zealand.
Eurasian Conformity mark: the single conformity mark
indicates that the product is approved for circulation
on the markets of the member states of the Eurasian
Customs Union.
This product complies with the Canadian standard ICES-
001/NMB-001 concerning electromagnetic compatibility.
CAN ICES/NMB-1
This symbol indicates that Monitor UVis-920 has been
certified by a Nationally Recognized Testing Laboratory
(NRTL). NRTL means an organization, which is recognized
by the US Occupational Safety and Health Administra-
tion (OSHA) as meeting the legal requirements of Title
29 of the Code of Federal Regulations (29 CFR), Part
1910.7.
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2 Safety instructions
2.2 Labels

2.3 Emergency procedures
Introduction
This section describes how to perform an emergency shutdown of Monitor UVis-920.
The section also describes the result in the event of power failure.
Emergency shutdown
In an emergency situation, do as follows to stop the run:
Switch off power to the instrument by switching the On/off switch on the rear panel to
the (O) position. If required, disconnect the mains power cord. The run is interrupted
immediately.
Power failure
In the event of power failure the run is interrupted immediately.
2.4 Recycling information
Decontamination
Monitor UVis-920 shall be decontaminated before decommissioning and all local regu-
lations shall be followed with regard to scrapping of the equipment.
Disposal, general instructions
When taking Monitor UVis-920 out of service, the different materials must be separated
and recycled according to national and local environmental regulations.
Recycling of hazardous
substances
Monitor UVis-920 contains hazardous substances. Detailed information is available from
your GE representative.
Monitor UVis-920 Operating Instructions 29055049 AD 17
2 Safety instructions
2.3 Emergency procedures

Disposal of electrical
components
Waste of electrical and electronic equipment must not be disposed as unsorted municipal
waste and must be collected separately. Please contact an authorized representative
of the manufacturer for information concerning the decommissioning of equipment.
2.5 Declaration of Hazardous Substances (DoHS)
根据SJ/T11364-2014《电子电气产品有害物质限制使用标识要求》特提供如下有关污染控制方面的
信息。
The following product pollution control information is provided according to SJ/T11364-2014 Marking
for Restriction of Hazardous Substances caused by electrical and electronic products.
电子信息产品污染控制标志说明
Explanation of Pollution Control Label
该标志表明本产品含有超过中国标准GB/T 26572 《电子电气产品中限用物质的限
量要求 》中限量的有害物质。标志中的数字为本产品的环保使用期，表明本产品
在正常使用的条件下，有毒有害物质不会发生外泄或突变，用户使用本产品不会
对环境造成严重污染或对其人身、财产造成严重损害的期限。单位为年。
为保证所申明的环保使用期限，应按产品手册中所规定的环境条件和方法进行正
常使用，并严格遵守产品维修手册中规定的定期维修和保养要求。
产品中的消耗件和某些零部件可能有其单独的环保使用期限标志，并且其环保使
用期限有可能比整个产品本身的环保使用期限短。应到期按产品维修程序更换那
些消耗件和零部件，以保证所申明的整个产品的环保使用期限。
本产品在使用寿命结束时不可作为普通生活垃圾处理，应被单独收集妥善处理。
This symbol indicates the product contains hazardous materials in excess of the limits
established by the Chinese standard GB/T 26572 Requirements of concentration
limits for certain restricted substances in electrical and electronic products. The
number in the symbol is the Environment-friendly Use Period (EFUP), which indicates
the period during which the hazardous substances contained in electrical and elec-
tronic products will not leak or mutate under normal operating conditions so that the
use of such electrical and electronic products will not result in any severe environmen-
tal pollution, any bodily injury or damage to any assets. The unit of the period is “Year”.
18 Monitor UVis-920 Operating Instructions 29055049 AD
2 Safety instructions
2.4 Recycling information

In order to maintain the declared EFUP, the product shall be operated normally ac-
cording to the instructions and environmental conditions as defined in the product
manual, and periodic maintenance schedules specified in Product Maintenance Pro-
cedures shall be followed strictly.
Consumables or certain parts may have their own label with an EFUP value less than
the product. Periodic replacement of those consumables or parts to maintain the
declared EFUP shall be done in accordance with the Product Maintenance Procedures.
This product must not be disposed of as unsorted municipal waste, and must be
collected separately and handled properly after decommissioning.
有害物质的名称及含量
Name and Concentration of Hazardous Substances
产品中有害物质的名称及含量
Table of Hazardous Substances’ Name and Concentration
有害物质
Hazardous substance
部件名称
Component name
多溴二苯醚
PBDE
多溴联苯
PBB
六价铬
(Cr(VI))
镉
Cd
汞
Hg
铅
Pb
00000X11000754
本表格依据SJ/T 11364的规定编制。
This table is prepared according to SJ/T 11364.
0: 表示该有害物质在该部件所有均质材料中的含量均在 GB/T 26572规定的限量要求以下。
X: 表示该有害物质至少在该部件的某一均质材料中的含量超出 GB/T 26572规定的限量要
求。
•此表所列数据为发布时所能获得的最佳信息.
0: Indicates that this hazardous substance contained in all of the homogeneous materials for
this part is below the limit requirement in GB/T 26572.
X: Indicates that this hazardous substance contained in at least one of the homogeneous
materials used for this part is above the limit requirement in GB/T 26572
•Data listed in the table represents best information available at the time of publication.
Monitor UVis-920 Operating Instructions 29055049 AD 19
2 Safety instructions
2.5 Declaration of Hazardous Substances (DoHS)

3 System description
The Monitor UVis-920 is a UV and visible light absorption monitor which can be used in
wavelengths range between 200-700 nm by changeable fixed wavelength filters. The
instrument contains no internal user replaceable items.
3.1 Illustrations
Main unit
12
FunctionPart
Main unit1
UV cell holder with cover2
20 Monitor UVis-920 Operating Instructions 29055049 AD
3 System description