Mind Media EEG User manual

This user guide has been created to educate and inform the reader about doing EEG
measurements with NeXus.
For more information about NeXus, our BioTrace+ software, please visit our website or
contact us.
www.mindmedia.com
The copyright of this document remains with Mind Media BV © 2018, and the contents of it may not be altered or
copied. However we do permit unlimited distribution by electronics means of this document in the unaltered digital
PDF format in which it is supplied. This document is not intended to replace scientific and clinical literature.
V2.3
User Guide
EEG

Page 2 of 66
Contents
Introduction.......................................................................................................................................3
Required Equipment..........................................................................................................................4
EEG measurement setup....................................................................................................................5
EEG/EXG sensor setup with disc electrodes .........................................................................................6
One position EEG .............................................................................................................................6
Two positions EEG .........................................................................................................................10
Four positions EEG.........................................................................................................................13
EEG/EXG sensor TP setup with Minicap electrodes............................................................................17
One position EEG ...........................................................................................................................17
Two positions EEG .........................................................................................................................20
Four positions EEG.........................................................................................................................23
EEG/EXG sensor TP setup with cup or ring electrodes .......................................................................26
One position EEG ...........................................................................................................................26
Two positions EEG .........................................................................................................................28
Four positions EEG.........................................................................................................................30
BioTrace+.........................................................................................................................................33
Appendix 1: 10-20 EEG system.........................................................................................................37
Appendix 2: Artifacts .......................................................................................................................38
Appendix 3: Care of materials..........................................................................................................39
Appendix 4: Linked-ear cable setup .................................................................................................40
EXG sensor setup with disc electrodes ...............................................................................................40
One position EEG ...........................................................................................................................40
Two positions EEG .........................................................................................................................43
Four positions EEG.........................................................................................................................46
EXG sensor TP setup with Minicap electrodes....................................................................................50
One position EEG ...........................................................................................................................50
Two positions EEG .........................................................................................................................53
Four positions EEG.........................................................................................................................56
EXG sensor TP setup with cup or ring electrodes ...............................................................................60
One position EEG ...........................................................................................................................60
Two positions EEG .........................................................................................................................62
Four positions EEG.........................................................................................................................64

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Introduction
This manual provides a step-by-step review of how to do EEG measurements with the
NeXus-4, NeXus-10 or NeXus-32. The manual provides information about the required
hardware, preparation and measurement steps, background information on artefacts
(appendix 1) and care of materials (appendix 2).

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Required Equipment
Depending on the chosen setup, the following items are required to perform EEG
measurements:
-Nexus-4, NeXus-10 or NeXus-32
-EXG Sensor, EEG Linked Ear Sensor (2 or 4 channel), EXG TP Sensor or EEG Linked Ear
TP Sensor (2 or 4 channel)
-EXG Ground or EXG Ground TP
-EEG Discs, EEG Disc Ear Electrodes, EEG Minicap Electrodes, cup or ring electrodes*
-Nuprep
-Electrode paste (e.g. Ten20) or Electro gel
-Ear clips for EEG discs or Ear clips for EEG Minicap electrodes
-Syringe with blunt needle (for Electro gel) or scoop (for Electrode paste)
-Minicap or Microcap
-Tissues
-Cotton swabs
-Measuring tape
-Skin marker
*Ag/AgCl electrodes.

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EEG measurement setup
The NeXus-4 can measure up to two positions EEG, the NeXus-10 up to 4 and the NeXus-32
up to 21 positions of EEG. Please refer to the User Guide NeXus-32 qEEG for a 21 channel cap
measurement.
NeXus-4
NeXus-10
NeXus-32
1 position EEG
2 positions EEG
4 positions EEG
21 positions EEG
Use the Internationally accepted 10-20 EEG system for EEG electrode placement, see
Appendix 1: 10-20 EEG system.
Choose an EEG measurement setup and then jump to BioTrace+ for further instructions on
software.
Before the actual measurement can start, the equipment has to be connected. Detailed information on
setting up the NeXus can be found in the NeXus User Manual or Quick Start.

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EEG/EXG sensor setup with disc electrodes
The following is required to perform EEG measurements in an EXG sensor setup with disc
electrodes:
-Nexus-4, NeXus-10 or NeXus-32
-EXG Sensor or EEG Linked Ear Sensor (2 or 4 channel)
-EXG Ground
-EEG Discs (Ag/AgCl) or EEG Disc Ear Electrodes*
-Nuprep
-Electrode paste (e.g. Ten20)
-Ear clips for EEG Disc (Ear) Electrodes
-Measuring tape
-Tissue
-Cotton swabs
-Measuring tape
-Skin marker
-Scoop
* Recommended use is 10-20 times. The layer of Ag/AgCl will gradually wear off influencing
signal quality.
* For placing EEG electrodes on the ears with EEG/EXG sensors with LOT numbers L2101 and
onwards (February 2021), the EEG Disc Ear Electrodes are used in combination with ear clips.
One position EEG
Connect the EXG Sensor to input A&B of the NeXus-4 or NeXus-10 and input 25&26 of the
NeXus-32. Make sure the red dot of the connector is facing downward with the NeXus-4 or
NeXus-10 or upward with the NeXus-32. With the EXG sensor A1/M1 or A2/M2 are used as
reference. Alternatively, the EEG Linked Ear sensor (2 or 4 channel) can be used for a single
channel linked ear referenced setup. In that case, the placement of reference and ground is
similar to two positions EEG setup. A bipolar measurement setup will be created by placing
the reference on the head, according to the 10-20 system.
Connect the EXG Ground to the Ground (Gnd) of the NeXus.
Sensors can be disconnected by pulling the silver ribbed part of the connector backward.

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Place a disc electrode on to the red snap-on of pair one of the EXG sensor.
Place the black snap-on of pair one of the EXG sensor and the ground snap-on together with
EEG disc (ear) electrodes on to an ear clip.
For placing EEG electrodes on the ears with EEG/ExG sensors with LOT numbers L2101 and
onwards (February 2021), the EEG Disc Ear Electrodes are used in combination with ear clips:
Determine electrode positions according to the 10-20 system by using measuring tape and
marking positions with a skin marker.
Rub the skin with a cotton swab and Nuprep at all electrode positions. Remove residual gel
with a tissue. As an alternative to using Nuprep, alcohol pads are sometimes used.

Page 8 of 66
Use the clip of the EXG cable to attach the EXG sensor to prevent pulling of the cables.
Apply some electrode paste (e.g. Ten20) to the electrodes by using for example a scoop.
Place the ear clip with the black (reference) snap-on with electrode on to the earlobe of the
same side (ipsilateral) of the location of interest.
Place the ear clip with ground snap-on with electrode on to the other earlobe.
Place the red (positive) snap-on with electrode on to the skin at the location of interest.

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Minicap
Optionally use the Minicap or Microcap to fix the electrodes. The Minicap also allows for
placing the electrodes on the mastoids instead of the ear.
Now go to chapter ‘BioTrace+’ for further instructions.

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Two positions EEG
Connect the EXG Sensor to input A&B of the NeXus-4 or NeXus-10 and input 25&26 of the
NeXus-32. Make sure the red dot of the connector is facing downward with the NeXus-4 or
NeXus-10 or upward with the NeXus-32.
With the EXG sensor A1/M1 or A2/M2 are used as reference. A bipolar measurement setup
will be created by placing the reference on the head, according to the 10-20 system. Use the
EEG Linked Ear sensor (2 or 4 channel), to create a linked-ear reference for both positive
electrodes. For use of the older linked ear cable, please refer to Appendix 4: Linked Ear cable
setup.
Connect the EXG Ground to the Ground (Gnd) of the NeXus.
Sensors can be disconnected by pulling the silver ribbed part of the connector backward.
Place disc electrodes on to the two red snap-ons and place a disc electrode on to the EXG
ground snap-on.
Place the two black snap-ons together with disc electrodes on to an ear clip.
For placing EEG electrodes on the ears with EEG/EXG sensors with LOT numbers L2101 and
onwards (February 2021), the EEG Disc Ear Electrodes are used in combination with ear clips:

Page 11 of 66
Determine electrode positions according to the 10-20 system by using measuring tape and
marking positions with a skin marker.
Rub the skin with a cotton swab and Nuprep at all electrode positions. Remove remaining
gel with a tissue. As an alternative to using Nuprep, alcohol pads are sometimes used.
Use the clip of the EXG cable to attach the EXG sensor to prevent pulling of the cables.
Apply some electrode paste (e.g. Ten20) to the electrodes by using for example a scoop.

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Place the ear clips with the black (reference) snap-on with electrode on to the left and right
earlobe.
Place the ground electrode preferably near the other reference electrodes on the scalp.
Place the red (positive) snap-ons with electrode on to the skin at the location of interest.
Minicap
Optionally use the Minicap or Microcap to fix the electrodes.
Now go to chapter ‘BioTrace+’ for further instructions.

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Four positions EEG
When measuring four positions EEG, a linked-ear setup is recommended. Connect both EEG
Linked Ear sensor connectors to input A&B and C&D on the NeXus-10 or input 25&26 and
27&28 on the NeXus-32. Make sure the red dot of the connector is facing downward with the
NeXus-10 or upward with the NeXus-32. For a 4 positions EEG setup with the older EEG linked-
ear cables and EXG sensor, please refer to Appendix 4: Linked Ear cable setup. A bipolar
measurement setup will be created by placing the reference on the head, according to the 10-
20 system.
Sensors can be disconnected by pulling the silver ribbed part of the connector backward.
Connect the EXG Ground to the Ground (Gnd) of the NeXus.
EEG Linked Ear Sensor
The two parts of the linked ear sensor should already be connected by a small black tube as
shown below.

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Place disc electrodes on to the four red snap-ons and place a disc electrode on to the EXG
ground snap-on.
Place the two black snap-ons together with disc electrodes on to an ear clip.
For placing EEG electrodes on the ears with EEG/ExG sensors with LOT numbers L2101 and
onwards (February 2021), the EEG Disc Ear Electrodes are used in combination with ear clips:
Determine electrode positions according to the 10-20 system by using measuring tape and
marking positions with a skin marker.
Rub the skin with a cotton swab and Nuprep at all electrode positions. Remove remaining
gel with a tissue. As an alternative to using Nuprep, alcohol pads are sometimes used.

Page 15 of 66
Use the clip of the EXG cable to attach the EXG sensor to prevent pulling of the cables.
Apply some electrode paste (e.g. Ten20) to the electrodes by using for example a scoop.
Place the ear clips with the black (reference) snap-on with electrode on to the left and right
earlobe.
Place the ground electrode preferably near the other reference electrodes on the scalp.
Place the red (positive) snap-ons with electrode on to the skin at the location of interest.

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Minicap
Optionally use the Minicap or Microcap to fix the electrodes.
Now go to chapter ‘BioTrace+’ for further instructions.

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EEG/EXG sensor TP setup with Minicap electrodes
The following is required to perform EEG measurements in an EXG sensor TP or EEG Linked
Ear TP setup with minicap electrodes:
-Nexus-4, NeXus-10 or NeXus-32
-EXG Sensor TP or EEG Linked Ear TP Sensor (2 or 4 channel)
-EXG Ground TP
-EEG Minicap Electrodes (sintered Ag/AgCl)
-Electro gel
-Ear clips for EEG Minicap electrodes
-Syringe with blunt needle
-Minicap or Microcap
-Tissue
-Cotton swabs
-Measuring tape
-Skin marker
One position EEG
Connect the EXG Sensor to input A&B of the NeXus-4 or NeXus-10 and input 25&26 of the
NeXus-32. Make sure the red dot of the connector is facing downward with the NeXus-4 or
NeXus-10 or upward with the NeXus-32. With the EXG sensor A1/M1 or A2/M2 are used as
reference. Alternatively, the EEG Linked Ear sensor (2 or 4 channel) can be used for a single
channel linked ear referenced setup. In that case, the placement of reference and ground is
similar to two positions EEG setup.
Connect the EXG Ground TP to the Ground (Gnd) of the NeXus.
Sensors can be disconnected by pulling the silver ribbed part of the connector backward.
Place Minicap electrodes on to pair one of the EXG sensor TP and place a Minicap electrode
on to the EXG ground TP. Slightly twist the connector in to EXG TP connection in order to make
good connection.

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Place the black TP connection (reference) with electrode of pair one and the ground with
electrode on to an ear clip.
Determine electrode positions according to the 10-20 system by using measuring tape and
marking positions with a skin marker.
Use the clip of the TP cable to attach the TP sensor to prevent pulling of the cables.
Place the Minicap or Microcap on the head.
Apply some Electro gel to the electrodes by using a cotton swab or a syringe with blunt
needle.

Page 19 of 66
Place the ear clip with the black (reference) electrode on to the earlobe of the same side
(ipsilateral) of the location of interest.
Place the ear clip with ground snap-on with electrode on to the other earlobe.
Place the red (positive) electrode on to the skin at the location of interest. Use the Minicap
or Microcap to fix the electrode. The Minicap also allows for placing the electrodes on the
mastoids instead of the ear. In that case the ear clips are not necessary.
Now go to chapter ‘BioTrace+’ for further instructions.
Due to the fluid nature of electro gel, rubbing the skin with an abrasive gel is usually not necessary.
When using electrode paste (e.g. Ten20), rub the skin with a cotton swab and Nuprep at all
electrode positions. The location of the ground electrode is preferably near other electrodes on the
scalp. Remove residual gel with a tissue. As an alternative to using Nuprep, alcohol pads are
sometimes used.

Page 20 of 66
Two positions EEG
Connect the EXG Sensor to input A&B of the NeXus-4 or NeXus-10 and input 25&26 of the
NeXus-32. Make sure the red dot of the connector is facing downward with the NeXus-4 or
NeXus-10 or upward with the NeXus-32.
With the EXG sensor A1/M1 or A2/M2 are used as reference. Use the EEG Linked Ear sensor
(2 or 4 channel), to create a linked-ear reference for both positive electrodes. For use of the
older linked ear cable, please refer to Appendix 4: Linked Ear cable setup.
Connect the EXG Ground TP to the Ground (Gnd) of the NeXus.
Sensors can be disconnected by pulling the silver ribbed part of the connector backward.
Place Minicap electrodes on to the red and black TP connections and place a Minicap electrode
on to the EXG ground TP. Slightly twist the connector in to EXG TP connection in order to make
good connection.
Place the black TP connection (reference) electrodes on to an ear clip.
Determine electrode positions according to the 10-20 system by using measuring tape and
marking positions with a skin marker.
Use the clip of the TP cable to attach the TP sensor to prevent pulling of the cables.