MO BIO Laboratories PowerLyzer 12155 User manual

INSTRUCTION MANUAL
PowerLyzer™24 Bench Top Bead-Based
Homogenizer
MO BIO Laboratories, Inc.
2746 Loker Avenue West
Carlsbad, CA 92010
P: [phone]
F: [phone]
www.mobio.com
13155 rev. 070110

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WARRANTY INFORMATION
This instruction manual is a guide for the use of the PowerLyzer™24 Bench Top Bead-Based
Homogenizer and accessories.
Data herein has been verified and validated. It is believed adequate for the intended use of the
instrument. If the instrument or procedures are used for purposes other than specified herein,
confirmation of the validity and suitability should be obtained; otherwise MO BIO Laboratories, Inc.
does not guarantee results and assumes no obligation or liability. This publication is not a license to
operate under, or a recommendation to infringe upon, any process patents.
Notes, cautions, and warnings within the text of this manual are used to emphasize important and
critical instructions.
This MO BIO Laboratories, Inc. product is warranted to be free from defects in material and
workmanship for a period of ONE YEAR from the date of delivery. MO BIO Laboratories, Inc. will
repair or replace and return free of charge any part which is returned to its factory within said period,
transportation prepaid by user, and which is found upon inspection to have been defective in materials
or workmanship. This warranty does not include normal wear from use; it does not apply to any
instrument or parts which have been altered by anyone other than an employee of MO BIO
Laboratories, Inc. nor to any instrument which has been damaged through accident, negligence, failure to
follow operating instructions, the use of electric currents or circuits other than those specified on the
plate affixed to the instrument, misuse, or abuse. MO BIO Laboratories, Inc. reserves the right to
change, alter, modify, or improve any of its instruments without any obligation to make corresponding
changes to any instrument previously sold or shipped.
THE FORGOING OBLIGATION IS IN LIEU OF ALL OBLIGATIONS AND LIABILITIES INCLUDING
NEGLIGENCE AND ALL WARRANTIES OF MERCHANTABILITY OR OTHERWISE, EXPRESSED OR
IMPLIED IN FACT OR BY LAW, AND STATE OUR ENTIRE AND EXCLUSIVE LIABILITY AND
BUYERS EXCLUSIVE REMEDY FOR ANY CLAIM OF DAMAGES IN CONNECTION WITH THE SALE
OR FURNISHING OF GOODS OR PARTS, THEIR DESIGN, SUITABILITY FOR USE, INSTALLATION,
OR OPERATION. MO BIO LABORATORIES, INC. WILL IN NO EVENT BE LIABLE FOR ANY
SPECIAL OR CONSEQUENTIAL DAMAGES WHATSOEVER, AND THEIR LIABILITY UNDER NO
CIRCUMSTANCES WILL EXCEED THE CONTRACT PRICE FOR THE GOODS FOR WHICH
LIABILITY IS CLAIMED.

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IMPORTANT SAFEGUARDS
READ ALL INSTRUCTIONS BEFORE USING. SAVE THIS INSTRUCTION MANUAL.
The PowerLyzer™24 Homogenizer has been engineered for maximum functionality as well as safety;
however, basic safety precautions and common sense must always be demonstrated when using any
electrical product. Do not attempt to modify any part of the PowerLyzer™24 Homogenizer. If you
experience problems with or have questions about your PowerLyzer™24 Homogenizer, contact
Technical Support at MO BIO Laboratories, Inc. at 1-800-606-6246 or 760-929-9911.
DANGER
DO NOT allow the machine to be submerged in any liquid.
DO NOT use in any setting other than an indoor laboratory.
DO NOT plug power cord into an incorrect outlet.
WARNING
To reduce the risk of burns, electrocution, fire, or injury:
Use this product only for its intended purpose as described in this manual. Do not use
attachments not recommended by the manufacturer.
Check that the proper power cord is plugged into the correct outlet, and that the voltage
selection switch located on the back of the unit has been selected to the correct voltage for
your country.
DO NOT operate the product if it is damaged in any way.
Keep this product away from heated surfaces.
Biological Risks
Wear gloves when handling samples and strictly follow all of the safety instructions related to bio-
hazardous agents to prevent any risk of contamination. The waste produced by the normal
operation of the instrument must be disposed of in biological waste containers and handled by
specialized companies.

MO BIO Laboratories, Inc. | 1-800-606-6246 | www.mobio.com 13155 rev. 070110 3
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Table of Contents 
WARRANTY INFORMATION.................................................................................................... 1
SECTION 1. POWERLYZER™24 BENCH TOP BEAD-BASED HOMOGENIZER............... 4
1.1 IMPORTANT INFORMATION.......................................................................................................................... 4
1.2 SPECIFICATIONS..................................................................................................................................................5
1.3 PARTS.......................................................................................................................................................................6
SECTION 2. SET UP AND OPERATION.................................................................................. 8
2.1 UNPACKING THE POWERLYZER™24 HOMOGENIZER.......................................................................8
2.2 TUBE MOTION ...................................................................................................................................................10
2.3 PROGRAMMING.................................................................................................................................................10
2.4 KEYPAD LAYOUT..............................................................................................................................................11
2.5 START UP OF THE EQUIPMENT...................................................................................................................12
2.6 LOADING SAMPLE TUBES ..............................................................................................................................13
2.7 PROGRAM SETTINGS.......................................................................................................................................15
2.8 ADJUSTING PARAMETERS..............................................................................................................................16
2.9 RECOMMENDED SETTINGS ..........................................................................................................................19
2.10 HOMOGENIZER SPEED CONVERSION TABLE ...................................................................................20
SECTION 3. TROUBLESHOOTING........................................................................................ 21
3.1 ERROR MESSAGES ............................................................................................................................................21
3.2 TROUBLESHOOTING ...................................................................................................................................21
SECTION 4. MAINTENANCE .................................................................................................. 22
4.1 REGULAR MAINTENANCE.............................................................................................................................22
4.2 CLEANING AND DECONTAMINATION ..................................................................................................23
SECTION 5. TRANSPORT AND STORAGE .......................................................................... 24
5.1 TRANSPORTING THE POWERLYZER™ 24 HOMOGENIZER............................................................24
5.2 STORAGE..............................................................................................................................................................25
SECTION 6. SUPPORT AND SERVICE................................................................................... 25
6.1 ASSISTANCE.........................................................................................................................................................25
6.2 DECONTAMINATION .....................................................................................................................................25
6.3 DECONTAMINATION CERTIFICATION FORM .....................................................................................26

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SECTION 1. POWERLYZER™24 BENCH TOP BEAD-BASED
HOMOGENIZER
1.1 IMPORTANT INFORMATION
This instruction manual includes all required information regarding unpacking, installation, operation, and
maintenance of the PowerLyzer™24 BenchTop Bead-Based Homogenizer.
Operating this equipment in ways other than those detailed in this instruction manual may impair the
unit.
DO NOT turn the unit upside down: the PowerLyzer™24 Homogenizer must always rest
on all four feet to avoid damaging internal components or breaking the housing.
DO NOT operate the unit when the housing is removed; potentially lethal voltage exists
within the instrument.
DO NOT operate the unit with the safety ground disconnected.
DO NOT overfill the tubes as this may lead to liquid contamination and compromise the
safety of the unit.
CHECK that the proper power cord is plugged into the correct outlet, and that the voltage
selection switch located on the back of the unit has been selected to the correct voltage for
your country.
 
USA: 115V Power Cord European: 230V Power Cord
W
ARNING: Check that the voltage indicated on the rear panel of the unit matches the local power
supply.
RISK OF ELECTRIC SHOCK: Although this equipment is fully insulated and grounded, it is
important for all users to be aware of the potential hazard of using liquids close to a power supply. If
any liquids are spilled, immediately disconnect the instrument from the main power supply (remove
the power cord from the AC power input on the rear panel) and clean the equipment and the
surrounding area. DO NOT reconnect the equipment until it has been fully inspected.

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The PowerLyzer™24 Homogenizer has been designed to lyse and homogenize biological samples
contained in bead beating tubes at variable speeds. It can simultaneously process up to 24 samples in 2
ml tubes at very high speed.
Advantages of the PowerLyzer™24 Homogenizer:
Simultaneously homogenize 24 x 2 ml tubes
Greater sample flexibility for any type of sample processing; broader speed range, number of
cycles, time, dwell/pause
Unique front-loading tube position for ease of use and optimal bead beating interaction
Process hundreds of samples per day
99 custom programmable settings
Disposable tubes ensure no threat of cross-contamination or sample degradation
1.2 SPECIFICATIONS
Depth: 17 in./43.2cm
W
idth: 15.5 in./39.4cm
Height: 13 in./33cm (24 in./61cm tall with lid open)
W
eight: 54 lbs./24kg
Motor Speed: 500-5,000 rpm
Noise Level: <70db
Electrical Requirements: 115 volts, 60Hz or 230 volts, 50Hz
Standards
Approval/Compliance:
CE certified
CAUTION: This is a Class A apparatus. The equipment may cause radio-electric interference in a
residential environment. In this case, it is recommended that the user takes appropriate measures.

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1.3 PARTS
Prior to operation, please remove all parts from the shipping container and inspect for damaged or
missing parts. If any parts are found to be damaged or missing, please contact MO BIO Laboratories, Inc.
at 1-800-606-6246.
The PowerLyzer™24 Homogenizer consists of the following:
Description Quantity
Motor Drive Unit (115V or 230V) 1
Finger Plate 1 Black plastic
Tube Holde
r
1 Blue anodized aluminum
Power Cord 2
115V and 230V
Spare Fuse 1
Instruction Manual 1
Bead tubes for the PowerLyzer™24 Homogenizer are available separately from MO BIO.
Description Cat. no.
Metal Bead Tubes, 2.38 mm 13117-50
Ceramic Bead Tubes, 1.4 mm 13113-50
Ceramic Bead Tubes, 2.8 mm 13114-50
Glass Bead Tubes, 0.1 mm 13118-50
Glass Bead Tubes, 0.5 mm 13116-50
Carbide Bead Tubes, 0.25 mm 13121-50
Garnet Bead Tubes, 0.7 mm 13123-50
Garnet Bead Tubes, 0.15 mm 13122-50
NOTE: Use only accessories and disposables recommended by the manufacturer. Accuracy and
operating lifetime may be affected if alternative products are used. Any damage caused by non-
recommended products are not covered by the manufacturer’s warranty.

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Parts of the PowerLyzer™24 Homogenizer
Finger Plate
Keypad
Door Cove
r
Locking Latch
Main Power
Supply Plug
Hub Lock Switch to lock
Finger Plate and secure
tubes
Tube Holde
r
ON/OFF Switch
Fuses
Air Vent
Cooling Fan
Shipping Screws
115V/230V
Voltage Selection Switch

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SECTION 2. SET UP AND OPERATION
2.1 UNPACKING THE POWERLYZER™ 24 HOMOGENIZER
2.1 UNPACKING THE POWERLYZER™24 HOMOGENIZER
1. Unscrew the two external screws from the back of the unit to release the support plate.
2. Remove the PowerLyzer™24 Homogenizer from the box and place it on a clean, horizontal and
stable surface. WARNING HEAVY ITEM: use caution when lifting to avoid back injury.
W
ARNING: DO NOT connect the unit to the main power supply un
t
il installation is complete
and the correct voltage is selected. DO NOT turn the unit upside down. The PowerLyzer™24
Homogenizer must always rest on its four feet to avoid damaging internal components or breaking
the housing.
CAUTION: DO NOT lift the instrument by holding the door. It must be lifted by holding the
bottom of the unit. Unpack the PowerLyze
r
™
24 Homogenizer with care and inspect it carefully.
NOTE: SAVE the crate, pallet, protective foam, bubble wrap, support plate, and two screws
included with the shipping crate in case a return is necessary. The PowerLyzer™24 Homogenizer
must be shipped in an approved packaging crate to avoid damage which may invalidate the warranty.
Packaging crates may be purchased for a minimal charge. For shipping inquiries, contact MO BIO at
1-800-606-6246.

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3. Check that the voltage selection switch located at the back of the unit matches the voltage
delivered by your electric power supply.
4. Ensure that the air vents and the cooling fan are not covered. Allow at least 6 inches of space
around air vents for proper motor ventilation.
5. Plug the PowerLyzer™24 Homogenizer into the power supply using the proper compatible power
cord supplied (115V or 230V).
In the event of a malfunction or breakdown, grounding provides a path of least resistance for electric
current to reduce the risk of electric shock. This instrument is equipped with an electric cord which is
grounded to the chassis housing. The plug must be plugged in to an outlet that is properly installed and
grounded in accordance with all local codes and ordinances.
W
ARNING: If the voltage supplied to the
equipment is higher than what is indicated on
the voltage selection switch, the electronics
can be irreversibly damaged and the warranty
will be voided.
W
ARNING: DO NOT modify the plug or cords
t
hat are provided. Damaged or worn power
cords should be repaired or replaced immediately by a qualified electrician.