Siemens RAPIDLAB 248 User manual

248 91 001N Rev. T, 2008-04
Operator’s Manual

© 2008 Siemens Healthcare Diagnostics Inc.
All rights reserved.
No part of this manual or the products it describes may be reproduced by any means or in
any form without prior consent in writing from Siemens Healthcare Diagnostics Inc.
The 248 pH/Blood Gas Analyzer is for In Vitro Diagnostic Use.
Complement, Mate, Rapidlab and RapidQC are trademarks of
Siemens Healthcare Diagnostics.
Vacutainer is a trademark of Becton-Dickinson.
Nafion is a trademark of Dupont.
Virkon is a trademark of Antec International Limited.
Origin: UK
This operator’s manual contains complete instructions for setting up and using the
248. Service information for use by appropriately qualified personnel is also
available.
The 248 is intended for use by persons knowledgeable in safe laboratory practices.
If the 248 is not used in accordance with these instructions for use, the protection
provided by the equipment may be impaired.
The information contained in this manual was correct at the time of going to print.
However, Siemens Healthcare Diagnostics policy is one of continuous product
improvement and the right to change specifications, equipment and maintenance
procedures at any time, without notice, is reserved.
Siemens Healthcare Diagnostics Ltd.
Sir William Siemens Sq.
Frimley, Camberley, GU16 8QD, UK
Siemens Healthcare Diagnostics Inc.
Tarrytown, NY 10591-5097 USA

Intended Use
The 248 is designed for the fast and accurate determination of pH, pCO2and
pO2 in heparinized whole blood samples. The minimum sample volume is
60
μ L (capillary). The results are displayed on the alphanumeric display in a choice
of units: pH or H+nmol/L, and mmHg or kPa for pCO2and pO2.
The 248 also calculates the following parameters:
• standard and actual bicarbonate (HCO3
–std and HCO3 –act)
• total carbon dioxide content (ctCO2)
• blood and extra cellular fluid base excess (BE(B) or BE(ecf))
• oxygen saturation (O2SAT)
• oxygen content (O2CT)
• arterial-alveolar oxygen tension difference (pO2(A–a)) and
arterial-alveolar oxygen tension ratio (pO2(a/A)).
WARNING The 248 is designed to be grounded through the power supply lead (line
cord) for safe operation. For the safety of operating personnel and optimum
performance make sure that the instrument is only connected to a 3-prong socket
(outlet) that has an effective earth connection. If you are in any doubt about the safety
of your electrical supply system consult a competent, qualified electrician.
There are no user replaceable parts within the instrument. Do not remove the rear
cover from the 248.
Siemens Healthcare Diagnostics and its authorized Distributors and Agents consider
themselves responsible for the effects of safety, reliability and performance of the 248
only if:
• Assembly operations, extensions, re-adjustments, modifications or repairs are
only carried out by persons authorized by them.
• The electrical installation of the relevant room complies with IEC
requirements or the local regulatory code.
• The equipment is used in accordance with the instructions for use.
The 248 pH/Blood Gas Analyzer is classed as IEC Type B equipment (Class 1
equipment providing an adequate degree of protection against electric shocks
particularly regarding allowable leakage currents and reliability of the protective
earth connection).
The 248 is designed for continuous operation and should be connected to the power
supply at all times, so that it is always ready for use.
The analyzer complies with IEC 601 for electrical and operating safety. It was not
designed for use in an environment containing a flammable anaesthetic mixture with
air, oxygen or nitrous oxide and is not designed to give protection against the ingress
of liquids.
The 248 is listed by Underwriters Laboratories as meeting the requirements
of the following Standards for Safety.
UL 61010A-1 - Electrical Equipment for Laboratory Use; Part 1: General
Requirements
CSA C22.2 No. 1010.1 - Safety Requirements for Electrical Equipment for
Measurement, Control, and Laboratory Use, Part 1: General Requirements.
i

Understanding the Symbols
This section describes the symbols that may appear on the exterior of the system or on
packaging. The symbols on the system provide you with the location of certain components and
with warnings for proper operation. The symbols on the system or packaging provide you with
other important information.
Symbol Description
Shows the probe lever position for sampling from syringes and capillaries
Shows the probe lever position for sampling from ampules and other open
top containers
Cautions you not to spray this area with cleaning solutions or other fluids
that may damage sensitive parts of the system
Shows the direction of rotation of the pump
Cautions you about the risk of exposure to potential electrical hazards
Alerts you to important information about the fuses
Indicates that the input electricity is alternating current
Indicates the gas connectors
Alerts you to important information about gas bottle pressure
Conventions Used in this Manual
This manual uses the following text and symbol conventions.
Convention Description
Bold Bold type within text indicates either:
1. A screen name
For example, if the word ‘Ready’ appears as ‘Ready’, this indicates that
‘Ready’ appears on the top left of the screen as the screen name.
or
2. A key on the instrument
For example, if the number ‘1’ appears as ‘1’, it refers to the instrument
key marked ‘1’.
Caution statements provide information about conditions that may cause
product damage.
Biohazard statements alert you to potentially biohazardous conditions.
ii 248 Operator’s Manual

Understanding the Symbols
Symbol Description
Advises you to consult the instructions for use to obtain safety
related information
Indicates that the analyzer is classed as IEC Type B equipment (Class 1
equipment providing an adequate degree of protection against electric shocks
particularly regarding allowable leakage currents and reliability of the
protective earth connection)
Indicates that the system is listed by Underwriters Laboratories as meeting
U.S. and Canadian requirements for safety
Indicates that the system meets the requirements of the European Union
Indicates an in vitro diagnostic medical device
Manufacturer
Date of manufacture
Authorized Representative
Shows the manufacturer of the serial plate (Donprint)
Catalog Number
Cautions you about the risk of exposure to biohazards
Advises you to consult the operating instructions to obtain information
needed for the proper use of the instrument
Shows the area in which the date can be written in pencil
Fragile, handle with care
Temperature limitation (4˚ - 25˚C)
Harmful
Keep dry
Keep away from sunlight and heat
Sterile
248 Operator’s Manual iii

iv 248 Operator’s Manual
Understanding the Symbols
Symbol Description
Batch code
Serial Number
Use by
Control
Indicates maximum fill level
Do not re-use
Do not stack
Do not use if package is damaged
Keep this way up
Please recycle this packaging
Printed on recycled materials
Indicates compliance with Green Dot packaging standards
Indicates compliance with RESY packaging standards
This system contains certain toxic or hazardous substances or elements. The
environmental protection use period for this system is 50 years. The system
can be used safely during its environmental protection use period. The system
should be recycled immediately after its environmental protection use period
has expired.

v
Contents Page
Intended Use i
Conventions Used in this Manual ii
Understanding the Symbols ii
1 Understanding the System 1-1
248 pH/Blood Gas Analyzer Overview 1-1
The Front Panel 1-1
The Rear Panel 1-2
The 248 Software 1-4
Setup Options 1-7
Sample Information 1-9
Reagents 1-10
Waste Disposal 1-11
Calibration 1-12
QC 1-13
2 Operating the System 2-1
Ready Screen 2-1
Probe Lever Position 2-1
Analyzing Syringe Samples 2-2
Analyzing Capillary Samples 2-5
Measuring a Short Sample or a Sample with a Bubble 2-8
Requesting an Additional Calibration 2-9
Calibrating the Barometer 2-9
Recalling Last Sample Data 2-10
Analyzing QC Samples 2-11
Recalling the Last QC Data 2-13
Entering Standby Mode 2-14

vi 248 Operator’s Manual
Contents
3 Maintaining the System 3-1
Daily Maintenance 3-1
Weekly Maintenance 3-2
Quarterly Maintenance 3-2
Maintenance Schedule 3-3
Six-Monthly Maintenance 3-4
Emptying the Waste Bottle 3-4
Changing the Reagents 3-5
Deproteinizing the Sensors 3-7
Conditioning the Sensors 3-7
Using the Disinfect Routine 3-8
Stopping the 248 System 3-8
Using the Prime Routine 3-9
Checking the Gas Pressure and Changing the Cylinders 3-10
Checking the Gas Flow Rate 3-12
Changing the Pump Tubing, and Cleaning and Lubricating the Rollers 3-13
Refilling or Replacing the Measurement Sensors 3-17
Replacing the Reference Sensor Cassette 3-19
Replacing the Bottle Tubing 3-21
Cleaning or Replacing the Drip Tray 3-22
Replacing the Printer Paper 3-23
Replacing the Probe and Tubing and Probe Housing 3-24
Replacing the Probe Protector 3-28
Replacing the Pre-heater Tube 3-29
Clearing Blockages 3-31
Replacing a Fuse 3-34
Shutting Down the 248 3-35

Contents vii
Contents
4 Troubleshooting the System 4-1
Calibration Failures 4-1
Calibration or Slope Drift 4-1
Calibration or Slope No Endpoint 4-2
Calibration or Slope Outside Range 4-4
Fluidics Failure, Insufficient 7.3/6.8/Wash 4-5
Suspect Results 4-6
Sample Not Detected or Sampling Fault 4-7
Printer Problems 4-8
Hydraulic Problems 4-9
Heater Problems 4-10
Using the Troubleshooting Routines 4-10
Measurement Block Routine 4-10
Sample Flow Routine 4-12
Heater Routine 4-13
Electronics Routine 4-13
Roll Printer Routine 4-13
Using the Status Indicators 4-14
Other Problems 4-14
5 Configuring the System 5-1
Operating Setup 5-1
Setting QC Ranges 5-1
Setting Reference Ranges 5-2
Choosing Units 5-2
Selecting Calibration Method, and Entering Gas Values 5-2
Setting Printer Options 5-3

viii 248 Operator’s Manual
Contents
5 Configuring the System
Adjusting Correlation 5-3
System Setup 5-4
Changing Date and Time 5-4
Setting the Maintenance Prompts 5-5
Selecting Parameters 5-5
Changing Beeper Option 5-6
Changing Communication Options 5-6
Setting Security 5-6
Printing Setup Report 5-7
Service Setup 5-7
Entering System Information 5-7
Changing Language 5-7
6 Service and Supplies 6-1
Ordering Information 6-1
Spares 6-1
Reagents 6-3
Addresses 6-4
Warranty 6-6
Appendix A Protecting Yourself From Biohazards A-1
Appendix B Precautions and Hazards B-1
Appendix C References C-1
Appendix D Interfacing to External Devices D-1
Appendix E Specifications E-1
Appendix F Installation F-1
Appendix G Operating Principles G-1