SYSMEX BEYOND A BETTER BOX RU-21 User manual

RU-21TM
REAGENT PREPARATION UNIT
QUICK GUIDE
BEYOND A BETTER BOX™

2
RU-21 — SYSTEM OVERVIEW
Function
CELLSHEATHTM CCS is a concentrated form of CELLSHEATHTM. The XN-IPU monitors how
much CELLSHEATH CCS remains, and the RU log keeps track of reagent replacement, RO
water, the prepared CELLSHEATH, errors, and parts replacement.
The RU-21 uses the CELLSHEATH CCS plus the RO water to
prepare CELLSHEATH for use on the analyzers. This prepared
CELLSHEATH is stored in the supply tank.
When viewing the other reagents, the CELLSHEATH that is
being made by the RU-21 will always appear full. The lot # and
expiration date listed matches the information entered for the
CELLSHEATH CCS.
RO (Reverse Osmosis) Water Specications
The RU-21 requires Type II reagent grade water based on CLSI Reagent Water Specications*.
Water quality is veried by Sysmex pre-installation. After installation, it is the laboratory’s responsibility to check
and maintain water quality on a regular basis.
Detailed information related to water specications can be found in the RU-21 Instructions for Use.
Reagent Specications
Packaging
• 20L
• 2 x 4L (not shown)
Open Stability
• 60 days
Connectivity
The RU-21, reagent preparation unit, is designed for use with XN-Series analyzers.
Up to two XN analyzers may be connected; the RU-21 is controlled via the XN-IPU.

3
Reagent Replacement “CELLSHEATH CCS”  With Error
1. A Help window from the RU-21 menu will display “Replace CELLSHEATH CCS” in the error message list.
2. Click [OK] to display the Replace Reagent window.
3. Click the remaining reagent volume indicator for CELLSHEATH CCS.
4. Make sure the box is checked to replace the reagent.
5. Click in the ‘Reagent Code’ text entry eld.
6. Using the hand held barcode reader, scan the reagent code on the new box of CELLSHEATH CCS.
7. Click [OK].
8. Remove the cap from the new reagent container.
9. Remove the cap from the old reagent container.
10. Pull the dispensing set straight up.
11. Insert the dispensing set straight into the new reagent container.
12. Close the cap.
13. Click Execute in the Replace Reagent Window.
Reagent Replacement “CELLSHEATH CCS”  No Error
1. On the XN-IPU, click on the RU-2 control menu button.
2. Click on the submenu button (the wrench).
3. Select [Replace Reagent] from the menu that appears.
4. Click in the remaining reagent volume indicator for CELLSHEATH CCS.
5. Make sure the box is checked to replace the reagent.
6. Click in the ‘Reagent Code’ text entry eld.
7. Using the hand held barcode reader, scan the reagent code on the new box of CELLSHEATH CCS.
8. Click [OK].
9. Remove the cap from the new reagent container.
10. Remove the cap from the old reagent container.
11. Pull the dispensing set straight up.
12. Insert the dispensing set straight into the new reagent container.
13. Close the cap.
14. Click Execute in the Replace Reagent Window.
REAGENT REPLACEMENT

4
RU-21 — REAGENT REPLACEMENT
Troubleshooting - Switch from CELLSHEATH CCS to CELLSHEATH (SE-L)
(For Emergency Use Only)
The switch to CELLSHEATH may be made in the following circumstances
• Problem with the RO water / RO water system
• Problem with the RU-21
Connect CELLSHEATH via Supply Tank
1. Locate the Supply Tank.
2. Remove the silver sticker from the spout kit of the Supply Tank to uncover the
vent hole, store the sticker elsewhere on the cap (you will need again to cover
the vent hole).
3. Remove the spout kit from the Supply Tank.
4. Open the cube of CELLSHEATH and insert the spout kit from the Supply Tank.
5. Tighten the cap from the spout kit on the new cube of CELLSHEATH.
6. Use the original cap from the new cubitainer of CELLSHEATH to close the
supply tank.
7. Click the RU-2 control menu button.
8. Click on the submenu button (the wrench).
9. Click [RU -> CELLSHEATH].
10. Read the warning message and click [OK].
11. The Help window will appear with the message “Register CELLSHEATH”.
12. Click [Execute].
13. Click CELLSHEATH in the Reagent Replacement window (red “exchange”).
14. Click in the ‘Reagent Code’ entry eld.
15. Using the hand-held reader, scan the reagent code on the container of
CELLSHEATH that you connected to the system.
16. Click [Execute].
17. CELLSHEATH is now ready for use.
NOTE: The analyzer(s) are now getting CELLSHEATH directly from this cube. The undiluted CELLSHEATH CCS
using the RO water is being bypassed.

5
Troubleshooting - Extended RU-  Type II Water System Downtime
If you have made the switch from CELLSHEATH CCS to CELLSHEATH (SE-90L) and that cube runs out, you will
need to replace it.
Reagent Replacement - CELLSHEATH to CELLSHEATH (SE-L)
(For Emergency Use Only)
1. The ‘Help’ dialog box on the XN-IPU will appear when the system detects an empty reagent container.
2. Click [Reset Alarm] to silence the audible alert.
3. Wait for the solid red status light on the analyzer menu.
4. Replace the empty CELLSHEATH cubitainer with a full one.
5. DO NOT click [Execute] in the Help dialog box.
6. Click [Close] to minimize the Help dialog box.
7. Click the Remaining Reagent Volume Indicator.
8. Click CELLSHEATH.
9. Place a checkmark next to ‘Replace the Reagent’.
10. Click in the ‘Reagent Code’ entry eld.
11. Using the hand-held reader, scan the reagent code on the new container of CELLSHEATH that you
connected.
12. Click [Execute].
NOTE: If the aspiration errors appear again after reagent replacement, check to ensure that the new cube of
REAGENT REPLACEMENT
Returning to Normal Operations - CELLSHEATH to CELLSHEATH CCS
1. Locate the Supply Tank.
2. Remove the cap from the Supply Tank.
3. Loosen and remove the spout kit from the CELLSHEATH.
4. Insert the spout kit into the supply tank.
5. Move the silver sticker back into place covering the vent hole.
6. Tighten the cap of the spout kit on the Supply Tank and cover the Supply Tank.
7. Click the RU-2 control menu button.
8. Click on the submenu button (the wrench).
9. Click [CELLSHEATH -> RU].
10. Read the warning message and click [OK].
11. Click the Remaining Reagent Volume Indicator for CELLSHEATH.
12. Click CELLSHEATH in the Reagent Replacement window.
13. Place a checkmark next to ‘Replace the Reagent.’
14. Click in the ‘Reagent Code’ entry eld.
15. Using the hand-held reader, scan the reagent code on the container of CELLSHEATH CCS that is
connected to the system.
16. Click [Execute].

6
Pressure Adjustment . MPa Pressure Error
1. Click the RU-2 menu button in the control menu.
2. Click the submenu button.
3. Click [Show Status].
• The current air pressure will be displayed in the Show Status window from the RU
menu
• The ‘Air Pressure’ screen will also be displayed on the RU-21 LCD display so the
changes will be easily visible during adjustment
4. Push the cover located on the right side of the RU-21 so that it pops up, then open the
door.
5. Pull out the adjustment knob on the 0.07 MPa regulator to unlock it.
6. Turn clockwise to increase pressure, and counter-clockwise to decrease pressure
(0.070 MPa ± 0.005).
7. After reaching an acceptable level, push the adjustment knob on the
0.07 MPa regulator to lock it.
8. Click [Close] on the ‘Show Status’ window from the RU-2 menu.
Watch the RU-21 LCD while you make the adjustment
RU-21 — TROUBLESHOOTING

7
Troubleshooting at the RU-
If an error occurs in the RU-21 an error message will appear. An error that has occurred can be cleared from the
error list, which is opened by touching the Help button.
1. To clear the error, touch [OK] to close the Error message, then touch the [Help] button.
2. Touch [Detail].
3. Follow the directions on the screen and press [OK] to clear each error.
TROUBLESHOOTING
Help button
Detail button

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Document Number 1369-CFL, Rev 1, 8/
Program availability varies by location. Programs and specification subject to change without notice.
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