Thermo Scientific Dionex User manual

Dionex Integral Process Analytical
Systems Operator’s Manual
Document No. 065250
Revision 06
March 2020

© 2020 by Thermo Fisher Scientific Inc. All rights reserved.
Chromeleon and UltiMate 3000 are registered trademarks of Thermo Fisher
Scientific Inc. in the United States.
Microsoft and Windows are registered trademarks of Microsoft Corporation in the
United States and other countries. Adobe is a registered trademark of Adobe
Systems, Incorporated in the United States and other countries.
The following are registered trademarks in the United States and possibly other
countries: NOWPak is a registered trademark of ATMI, Inc. PharMed is a registered
trademark of Saint-Gobain Performance Plastics Corporation.
PEEK is a trademark of Victrex PLC.
All other trademarks are the property of Thermo Fisher Scientific Inc. and its
subsidiaries.
Thermo Fisher Scientific Inc. provides this document to its customers with a product
purchase to use in the product operation. This document is copyright protected; any
reproduction of the whole or any part of this document is strictly prohibited, except
with the written authorization of Thermo Fisher Scientific Inc.
This manual is provided “as is.” The contents of this manual are subject to being
changed, without notice, in future revisions.
Thermo Fisher Scientific Inc. makes no representations that this document is
complete, accurate, or error-free. Thermo Fisher Scientific Inc. assumes no
responsibility and will not be liable for any errors, omissions, damage, or loss that
might result from any use of this document, even if the information in the document
is followed properly.
This document is not part of any sales contract between Thermo Fisher Scientific
Inc. and a purchaser. This document shall in no way govern or modify any Terms and
Conditions of Sale. The Terms and Conditions of Sale shall govern all conflicting
information between the two documents.
Revision history: Revision 01 December 2008; initial release of system
Revision 02 released May 2010; lockout instructions added
Revision 03 released January 2012; Thermo Fisher Scientific transition
Revision 04 released October 2012; new part numbers assigned
Revision 05 released May 2018; references to Velcro and Dionex Reference Library
removed; manufacturing location and Dionex Technical Support phone number
updated
Revision 06 released March 2020; Chromeleon 7 Process Analyzer support added
For Research Use Only. Not for use in diagnostic procedures.

Doc. 065250-06 03/2020 i
1 • Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
1.1 Dionex Integral Process Analytical Systems . . . . . . . . . . . . . . . . . . . . . . 1
1.1.1 Dionex Integral System Components . . . . . . . . . . . . . . . . . . . . . 3
1.1.2 Chromatography Systems Supported . . . . . . . . . . . . . . . . . . . . . 4
1.1.3 Dionex Integral System Control . . . . . . . . . . . . . . . . . . . . . . . . . 4
1.2 Dionex Integral System Operator’s Manual . . . . . . . . . . . . . . . . . . . . . . 6
1.3 Related Documentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
1.4 Safety Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
1.4.1 Safety Messages and Notes . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
1.4.2 Safety Symbols . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
1.5 Regulatory Compliance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11
1.5.1 Notice on Lifting and Handling of Thermo Scientific
Instruments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12
1.5.2 Notice on the Proper Use of Thermo Scientific Instruments . . 12
1.5.3 Notice on the Susceptibility to Electromagnetic Transmission 12
1.5.4 WEEE Compliance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
1.5.5 Safety Practices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
2 • Dionex Integral System Configurations . . . . . . . . 17
2.1 Example Configurations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
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3 • SP Sample Preparer Description. . . . . . . . . . . . . . . . . .19
3.1 SP Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19
3.2 SP Enclosures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19
3.3 SP Power and Computer Connections . . . . . . . . . . . . . . . . . . . . . . . . . .21
3.4 SP Liquid Leak Sensor and Drain . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23
3.5 SP Component Descriptions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24
3.5.1 Metering Valve (Rotary Valve) . . . . . . . . . . . . . . . . . . . . . . . . .24
3.5.2 Dilution Vessels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
3.5.3 Dilution Pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26
3.5.4 Loading Pumps . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
3.5.5 Solenoid Valves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28
3.5.6 Vial Cooler (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29
3.6 SP Panel Configurations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29
3.6.1 SP1 for Concentration or Direct Injection . . . . . . . . . . . . . . . . .29
3.6.2 SP2 for Dilution or Direct Injection . . . . . . . . . . . . . . . . . . . . .33
3.6.3 Flow Paths and Valve Positions Used During Analyses . . . . . .38
3.6.4 SP Gas and Liquid Input and Output Lines . . . . . . . . . . . . . . . .44
3.7 Analog Inputs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .45
3.8 SP TTL and Relay Control (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . .48
3.8.1 Relay Output Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .49
3.8.2 TTL Input Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .49
3.9 Liquid Level Sensor (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .50
3.10 Flow Sensor (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .51
3.11 Pressure Sensor (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .53

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3.12 DC Voltage Control (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56
3.13 PWM Power Output (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
4 • SS Stream Selector Description . . . . . . . . . . . . . . . . . . 61
4.1 SS Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
4.2 Stream Selection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
4.3 SS Enclosures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63
4.4 SS Power and Computer Connections . . . . . . . . . . . . . . . . . . . . . . . . . . 64
4.5 SS Leak Sensor and Liquid Drain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
5 • AE Analyzer Enclosure Description . . . . . . . . . . . . . 67
5.1 AE Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67
5.2 AE Exterior Features . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68
5.3 AE Interior Features . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
5.3.1 Shelves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
5.3.2 Power Outlet Strip . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
5.3.3 Drip Tray and Liquid Drain . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
5.3.4 Liquid Leak Sensing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71
5.4 AE Power and Computer Connections . . . . . . . . . . . . . . . . . . . . . . . . . 72
5.5 AE TTL and Relay Connectors (Option) . . . . . . . . . . . . . . . . . . . . . . . 75
5.6 AE Ventilation Fan (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76
5.7 AE Air Conditioner/Heater (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . 76
5.8 AE Purge System (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77
5.9 AE Tower Light (Option) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78

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6 • LE Liquids Enclosure Description. . . . . . . . . . . . . . . .81
6.1 LE Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .81
6.2 LE Containers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .81
6.3 LE Control Panel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .82
6.4 LE Liquid and Gas Connections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .83
6.5 LE Pneumatic Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .83
7 • Startup, Operation, and Shutdown . . . . . . . . . . . . . . .85
7.1 Initial Startup Checklist . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .85
7.1.1 Prepare the Site and Facilities . . . . . . . . . . . . . . . . . . . . . . . . . .85
7.1.2 Connect the Facilities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .85
7.1.3 Connect the Communications Cables . . . . . . . . . . . . . . . . . . . .86
7.1.4 Connect the Sample Inlet Line . . . . . . . . . . . . . . . . . . . . . . . . .86
7.2 Initial Startup . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .86
7.2.1 Turn On the Power . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .86
7.2.2 Set Up Chromeleon 7 PA and Configure the System . . . . . . . .87
7.2.3 Flush the Flow Path . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .87
7.2.4 Install Consumable Components . . . . . . . . . . . . . . . . . . . . . . . .88
7.2.5 Calibrate the System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .88
7.2.6 Set Up the Dionex Integral Analyzers in Chromeleon 7 PA . . .91
7.3 Routine Startup and Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .92
7.3.1 Routine Startup . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .92
7.3.2 Routine Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .93

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7.4 Shutdown . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
7.4.1 Short-Term Shutdown . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
7.4.2 Long-Term Shutdown . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 94
8 • Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95
8.1 Daily Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95
8.2 Weekly Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97
8.3 Biweekly Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97
8.4 Monthly Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98
8.5 Quarterly Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 98
9 • Troubleshooting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99
9.1 Troubleshooting Strategies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 99
9.2 Audit Trail Error Messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100
9.3 Liquid Leaks/Leak Alarm . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118
9.4 Air and Gas Leaks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 120
9.5 System or System Component Does Not Power Up . . . . . . . . . . . . . . 121
10 • Service. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
10.1 Eliminating a Fluid System Restriction . . . . . . . . . . . . . . . . . . . . . . . . 123
10.2 Replacing Pump Check Valve Cartridges . . . . . . . . . . . . . . . . . . . . . . 124
10.3 Replacing Pump Check Valves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126
10.4 Replacing a Pump Piston Seal and Backup Seal . . . . . . . . . . . . . . . . . 127
10.5 Replacing a Pump Piston . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 132

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10.6 Replacing the Waste Valve Seal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .132
10.7 Accessing the Main SP Electronics Board . . . . . . . . . . . . . . . . . . . . . .134
10.8 Replacing an SP Solenoid Valve . . . . . . . . . . . . . . . . . . . . . . . . . . . . .136
10.9 Changing the Peristaltic Loading Pump Speed . . . . . . . . . . . . . . . . . .138
10.10 Calibrating Components . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .140
10.11 Changing the SP or SS Main Power Fuses . . . . . . . . . . . . . . . . . . . . . .140
A • Specifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .143
A.1 Environmental (All Analyzer Components) . . . . . . . . . . . . . . . . . . . . .143
A.2 AE Analyzer Enclosure and LE Liquids Enclosure . . . . . . . . . . . . . . .143
A.2.1 Electrical. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .143
A.2.2 Physical. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .144
A.3 SP Sample Preparer and SS Stream Selector . . . . . . . . . . . . . . . . . . . .144
A.3.1 Electrical. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .144
A.3.2 Physical . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .144
A.3.3 Pumps . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .145
A.3.4 Valves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .145
A.3.5 Dilution Vessels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .146
A.4 Air Conditioner/Heater . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .146
A.4.1 Electrical. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .146
A.4.2 Physical. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .147
B • Reordering Information. . . . . . . . . . . . . . . . . . . . . . . . . . . . .149

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C • TTL and Relay Installation Instructions. . . . . . . 151
C.1 Installing the SP TTL and Relay Kit . . . . . . . . . . . . . . . . . . . . . . . . . . 152
C.1.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152
C.1.2 SP TTL and Relay Kit Installation Procedure . . . . . . . . . . . . 152
C.2 Installing the AE TTL and Relay Kit . . . . . . . . . . . . . . . . . . . . . . . . . 157
C.2.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157
C.2.2 AE TTL and Relay Kit Installation Procedure . . . . . . . . . . . . 157
C.3 Installing the TTL and Relay Breakout Boards . . . . . . . . . . . . . . . . . . 160
C.3.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 160
C.3.2 TTL and Relay Breakout Board Installation Procedure . . . . . 161
C.4 Installing the AE Tower Light Kit . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169
C.4.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169
C.4.2 AE Tower Light Kit Installation Procedure . . . . . . . . . . . . . . 169
D • AE Purge Kit Installation Instructions . . . . . . . . . 173
D.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173
D.2 AE Purge Kit Installation Procedure . . . . . . . . . . . . . . . . . . . . . . . . . . 174
D.2.1 Installing the Purge Control Unit . . . . . . . . . . . . . . . . . . . . . . 174
D.2.2 Installing the Purge Orifice/Spark Arrestor and the
Pressure Relief Valve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 179
D.2.3 Sealing All Openings in the Enclosures . . . . . . . . . . . . . . . . . 181

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E • Peristaltic Pump Kit Installation
Instructions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .183
E.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .183
E.2 Peristaltic Pump Installation Procedure . . . . . . . . . . . . . . . . . . . . . . . .183
E.2.1 Installing the Peristaltic Pump on the SP Panel . . . . . . . . . . . .184
E.2.2 Connecting the Pump Cable . . . . . . . . . . . . . . . . . . . . . . . . . .184
E.2.3 Assembling the Peristaltic Tubing and Fittings . . . . . . . . . . . .186
E.2.4 Configuring the Pump in Chromeleon 7 . . . . . . . . . . . . . . . . .189
F • Liquid Level Sensor Installation
Instructions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .191
F.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .191
F.2 Liquid Level Sensor Installation Procedure . . . . . . . . . . . . . . . . . . . . .191
F.2.1 Installing the Liquid Level Sensor on the Reservoir or
Container . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .192
F.2.2 Plugging the Liquid Level Sensor Cable into the Main
SP Electronics Board . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .193
G • Thermal Options Installation Instructions . . . .195
G.1 Installing the Thermal Control Board Kit . . . . . . . . . . . . . . . . . . . . . . .195
G.1.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .195
G.1.2 Thermal Control Board Installation Procedure . . . . . . . . . . . .196
G.2 Installing the Vial Cooler . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .198
G.2.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .198

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G.2.2 Vial Cooler Installation Procedure . . . . . . . . . . . . . . . . . . . . . 198
G.3 Installing the Heated Dilution Vessel . . . . . . . . . . . . . . . . . . . . . . . . . 199
G.3.1 Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 199
G.3.2 Heated Dilution Vessel Installation Procedure . . . . . . . . . . . 200
H • Lockout Instructions for the AE, SP, or SS . . 203
H.1 Lockout Device Installation Procedure . . . . . . . . . . . . . . . . . . . . . . . . 203
H.1.1 Getting Ready . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 203
H.1.2 Installing a Lockout Device . . . . . . . . . . . . . . . . . . . . . . . . . . 205
H.1.3 Re-energizing a Module . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 206
Index

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1 • Introduction
1.1 Dionex Integral Process Analytical Systems
Thermo Scientific™Dionex™Integral™Process Analytical Systems are designed
for reliability, accuracy, low maintenance, and regulatory compliance. Their IC
(ion chromatography) and HPLC (high-performance liquid chromatography)
capabilities allow determination of species that are not possible with other process
analytical techniques. Multicomponent characterization of a sample can be
performed in a single analysis and multiple samples can be scheduled for
automatic analysis.
A Dionex Integral system (see Figure 1-1) is configured to perform a specific
analysis. A system typically contains an analytical pump, a detector, and an SP
Sample Preparer.
A Dionex Integral analyzer consists of from one to four systems combined to
operate in parallel. The analyzer is configured to sequentially monitor up to 21
samples. An SS Stream Selector can be used to select a sample from multiple
sample streams.
Dionex Integral analyzers are controlled by Thermo Scientific™Dionex™
Chromeleon™7 Process Analyzer software running under Microsoft®Windows®
10 Enterprise or Windows®10 Pro.
Chromeleon 7 Process Analyzer (Chromeleon 7 PA, for short) incorporates a user
interface that provides an industry-standard approach to process monitoring,
industrial I/O, and process control. Chromeleon 7 PA instrument control
capabilities include:
•Scheduled sampling
•Synchronized operation of multiple systems
•Automatic alarm handling, using preprogrammed conditional responses

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Figure 1-1. Example Dionex Integral System
Dionex ICS-6000 Detector/
Chromatography Module
Dionex ICS-6000 Eluent
Generator
Chromeleon 7 Process
Analyzer Computer
SP Sample Preparer
Dionex ICS-6000 Dual Pump
3
4
2
56
LE Liquids Enclosure
7
2
3
4
5
6
7
1AE Analyzer Enclosure
1

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1.1.1 Dionex Integral System Components
The Dionex Integral Process Analytical Systems product line includes the
following components:
•AE Analyzer Enclosure
•LE Liquids Enclosure
•SP Sample Preparer
•SS Stream Selector
AE Analyzer Enclosure
The AE provides the liquid and gas connections, electrical connections,
electrical emissions shielding, and environmental protection often needed
in a process environment. The AE must be mounted on a wall, on top of
an LE Liquids Enclosure (see below), or on another appropriate support
structure.
LE Liquids Enclosure
The LE provides an enclosure for housing standard and reagent bottles, as
well as NOWPak®containers (for eluents and solvents). The LE includes
a gas supply control panel. The LE can provide a rolling base for an AE
Analyzer Enclosure.
SP Sample Preparer
The SP contains the valves and pumps required for sample and standard
preparation. Electronics built into the SP are used to control the SP
components. The SP is available in three versions (see Section 3.1).
SS Stream Selector
The SS can select one of 7, 14, or 21 sample streams, depending on the
number of valves installed inside the enclosure. Sample streams can be
continuously flushing or static, and can be returned to the process or
directed to waste.

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1.1.2 Chromatography Systems Supported
The following systems can be configured in a Dionex Integral system:
•Thermo Scientific™Dionex™ICS-6000 Ion Chromatography
Systems
•Thermo Scientific™Dionex™UltiMate™3000 Rapid Separation
(RS) HPLC Systems
•Thermo Scientific™Dionex™UltiMate™3000 Standard (SD) HPLC
Systems
1.1.3 Dionex Integral System Control
Dionex Integral systems are controlled by a computer configured with
Chromeleon 7 Process Analyzer software (Chromeleon 7 PA, for short).
This is an extended version of the Thermo Scientific™Dionex™
Chromeleon™7 Chromatography Data System.
Chromeleon 7 PA integrates Chromeleon 7 with a client program called
Analyzer. This adds several process monitoring functions (including
stream selection, sample preparation, and alarm configuration) to
Chromeleon 7.
Use Chromeleon 7 PA to:
•Specify the instrument server
•Specify the datasource
•Create analyzers and associate instrument systems with analyzers
•Create analyzer sequences
•Specify default and alarm sequences
•Configure alarm conditions and responses
Use Chromeleon 7 to:
•Create and control instrument systems
•Acquire and manage data
Chromeleon 7 can control a total of four systems configured in up to four
analyzers. Chromeleon 7 allows four instrument systems per server.
Figure 1-2 shows a system configured in one analyzer.

1 • Introduction
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Figure 1-2. Example Analyzer Configuration

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1.2 Dionex Integral System Operator’s Manual
The electronic version of the Dionex Integral system operator’s manual is an
Adobe®PDF (Portable Document Format) file. The file contains numerous links
that you can click to go to other locations within the manual. These links include:
•Cross-references (underlined in blue) to sections, figures, and tables
•Table of contents entries
•Index entries
Chapter 1
Introduction Provides an overview of Dionex Integral Process
Analytical Systems; includes brief descriptions
of Dionex Integral system components, the
software required for operation, and the user
manuals.
Chapter 2
System Configurations Provides an illustration of a typical Dionex
Integral system configuration.
Chapter 3
SP Sample Preparer
Description
Describes SP components and operating
features.
Chapter 4
SS Stream Selector
Description
Describes SS components and operating
features.
Chapter 5
AE Analyzer Enclosure
Description
Describes AE components and operating
features.
Chapter 6
LE Liquids Enclosure
Description
Describes LE components and operating
features.
Chapter 7
Startup, Operation, and
Shutdown
Lists tasks to be performed before beginning
operation of the Dionex Integral system.
Provides instructions for routine operation of the
Dionex Integral system and for short-term and
long-term shutdown procedures.

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Chapter 8
Maintenance Provides routine preventive maintenance
procedures for the Dionex Integral system.
Chapter 9
Troubleshooting Lists Chromeleon 7 audit trail error messages
(with possible causes and corrective actions to
take). Lists minor problems that may occur
during operation, along with procedures for how
to isolate and eliminate the cause of each
problem.
Chapter 10
Service Provides routine service and parts replacement
procedures the user can perform.
Appendix A
Specifications Lists specifications and installation site
requirements for the Dionex Integral system.
Appendix B
Reordering Information Lists spare parts for the Dionex Integral system.
Appendix C
TTL and Relay
Installation Instructions
Provides instructions for installing TTL and
relay control functions in the SP and AE.
Appendix D
AE Purge Kit Installation
Instructions
Provides instructions for installing a purge
system in the AE.
Appendix E
Peristaltic Pump
Installation Instructions
Provides instructions for installing a peristaltic
pump on the SP panel.
Appendix F
Liquid Level Sensor
Installation Instructions
Provides instructions for installing a liquid level
sensor on a liquid reservoir or NOWPak Bag-in-
a-Bottle container.
Appendix G
Thermal Options
Installation Instructions
Provides instructions for installing a vial cooler
and a heated dilution vessel on the SP panel.
Appendix H
Lockout Instructions for
AE, SP, and SS
Provides instructions for locking out the AE, SP,
and SS power connectors to prevent modules
from being powered up.

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1.3 Related Documentation
In addition to this operator’s manual, the following related documentation is
available. User manuals can be downloaded from the Thermo Fisher Scientific
website. Chromeleon 7 manuals are available on the software DVD, also.
Hardware Documentation
Additional hardware documentation includes the following:
•Dionex ICS-6000 Ion Chromatography System Operator’s Manual (includes
the DP/SP, DC, CD, and ED) (Document No. 22181-97002)
•Dionex™UltiMate™3000 RS and SD series module manuals
Consumable Product Documentation
For information about Dionex columns, suppressors, EluGen cartridges, and other
consumable products, refer to the appropriate product manual.
Software Documentation
Additional software documentation includes the following:
•For installation instructions for Chromeleon 7 PA, refer to Chromeleon 7.3
Installation Guide (Document No. 7329.0003).
•For information about how to set up and use Chromeleon 7 PA, refer to the
Chromeleon 7 PA Help. For information about how to use Chromeleon 7,
refer to the Chromeleon 7 Help. Both Help systems are installed with
Chromeleon 7.