Thermo Scientific SpeedVac SPD210 User manual

Installation and Operation
80302131 • Revision A • September 2018
SpeedVac™ SPD210
Vacuum Concentrator

IMPORTANT: Read this instruction manual. Failure to follow the instructions in this manual can result in
damage to the product, injury to operating personnel, and poor equipment performance.
CAUTION: All internal adjustments and maintenance must be performed by qualified service personnel.
DISCLAIMER: Thermo Fisher Scientific Inc. does not accept any responsibility for any damage caused to its
products by unauthorized personnel.
Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to use in the
product operation. This document is copyright protected and any reproduction of the whole or any part of this
document is strictly prohibited, except with the written authorization of Thermo Fisher Scientific Inc.
The contents of this document are subject to change without notice. All technical information in this document
is for reference purposes only. System configurations and specifications in this document supersede all
previous information received by the purchaser.
© 2018 Thermo Fisher Scientific Inc. All rights reserved.

Contents
Introduction ................................................................. 1
Safety Precautions....................................................... 2
Operating Standards.................................................... 3
Product Specifications ............................................. 3
Environmental Conditions......................................... 3
Installation.................................................................... 4
Contents .................................................................. 4
Installation of SPD210 .............................................. 4
Operation..................................................................... 5
Description Of Control Panel .................................... 5
Manual Run.............................................................. 7
Auto Run.................................................................. 7
Drying Rate .............................................................. 8
Exporting Live Run Data........................................... 8
HyperTerminal Configuration .................................... 8
Lid Stay Mechanism................................................. 9
Other Topics ............................................................ 9
Rotors and Rotor Blocks .......................................... 10
Accessories ............................................................. 11
Appendix 1 .................................................................. 12
Additional SPD210 System Setup ............................ 12
Appendix 2 .................................................................. 13
Warranty ...................................................................... 14

SpeedVac™ SPD210 Introduction | 1
Introduction
Thermo Scientific Savant SpeedVac™ SPD210 vacuum
concentrator offers fast, reliable processing of samples. It
effectively removes non-aggressive organics such as
methanol, acetonitrile, water and HPLC fractions.
The combination of vacuum applied to the sample chamber
from an external source and centrifugal action promotes
solvent evaporation without sample loss due to foaming or
bumping. The evaporation process is accelerated with the
addition of chamber heat to counteract the extreme
evaporative cooling of the samples. The concentration
process is completed with the addition of a vapor
condensation trap available separately for virtually 100%
solvent recovery. This results in a thorough evaporation
process in a safe environment for both the sample and the
user. The unit features an advanced front panel with dual
timer for automatic or manual control of run conditions, it also
features three programs that are modifiable which enable user
to retrieve and store application protocols for future use.
The compact, SPD210 features:
• Good resistance to organic solvents with the following
provisions:
- Components made of Polypropylene®and Teflon®
used exclusively in the vapor path.
• Microprocessor control of run and heat times offer fully
unattended, automatic operation
• 3 programs that are modifiable for custom application-
based run parameters.

2 | Safety Precautions SpeedVac™ SPD210
Safety Precautions
In this manual, the following symbols and conventions are
used:
Below are important safety precautions that apply to this
product:
This symbol when used alone indicates
important operating instructions which reduce
the risk of injury or poor performance of the unit.
CAUTION: This symbol, in the context of a
CAUTION, indicates a potentially hazardous
situation which if not avoided could result in
minor to moderate injury or damage to the
equipment.
WARNING: This symbol, in the context of a
WARNING, indicates potentially hazardous
situations which, if not avoided, could result in
serious injury or death.
This symbol indicates situations where
dangerous voltages exist and potential for
electrical shock is present.
The snowflake symbol indicates extreme low
temperatures and high risk of frostbite. Do not
touch bare metal or samples with unprotected
body parts.
This symbol indicates possible pinch points
which may cause personal injury.
This symbol indicates a need to use gloves
during the indicated procedures. If performing
decontamination procedures, use chemically
resistant gloves.
Before installing, using or maintaining this
product, please be sure to read the manual and
product warning labels carefully. Failure to follow
these instructions may cause the product to
malfunction, which could result in injury or
damage.
This symbol represents protective conductor
terminal.
WARNING: Disconnect the unit from all power
sources before cleaning, troubleshooting, or
performing other maintenance on the product or
its controls.
WARNING: Do not use this device in
radioactive, highly reactive or explosive
atmosphere.
Do not use this device to process any explosive,
radioactive, highly reactive or explosive
atmosphere creating substances.

SpeedVac™ SPD210 Operating Standards | 3
Operating Standards
Product Specifications
*Dependent upon ambient temperature, line voltage fluctuation, and load capacity.
Environmental Conditions
Indoor use only, in the absence of hoarfrost, dew, percolating water, rain and solar radiation.
Main supply voltage fluctuations not to exceed ±10% of the nominal voltage.
Transient overvoltages per Installation Categories II.
Operative Power* 115 VAC; 60 Hz; 8 amps
230 VAC; 50 Hz; 6 amps
Vacuum Chamber TEFLON®coated chemical resistant aluminum casting
Cover Glass cover - includes a safety interlock
Induction Motor Maintenance free
Bearings Standard
Chamber temperature 35°C to 65°C, 5°C increments
Weight 117 lbs
53 kg
Dimensions (W x D x H) 19 in x 26 in x 18 in
48 cm x 66 cm x 46 cm
Fuse 8 A, 250 VAC, Time-lag
6 A, 250 VAC, Time-lag
Maximum altitude 2000 meters above mean sea level
Ambient temperature range 17°C to 32°C
Humidity 20% to 80% non-condensing
Pollution degree 2

4 | Installation SpeedVac™ SPD210
Installation
Contents
Unpacking. Open the shipping cartons. Carefully remove the
instrument and accessories. Lift and carry with two
people, holding securely underneath with both hands.
Use proper lifting technique (lift with the legs, not the
back) to avoid personal injury. Compare the contents with
the packing list. If there is a discrepancy, call Thermo
Scientific technical service.
Inspection. Inspect the unit and accessories for damage that
may have occurred during shipment. Should there be any
damage, report it to the carrier and contact Thermo Scientific
immediately. Make sure the carrier inspects the damage and
leaves an inspection report. Register any claims for shipping
damage against the carrier or his agent. Save the shipping
carton in the event a return is necessary. Call Thermo
Scientific technical service for further assistance.
Site preparation. The SPD210 requires a stable surface that
is clean, dry, level, and within 4 feet (1.2 meters) of a
compatible electrical outlet. Place the unit in a convenient
location with access to a vacuum source and a vapor trap1.
The SPD210 units configured for 115 VAC, 60 Hz, should be
plugged into a circuit rated for at least 8 amps. The SPD210
units configured for 230 VAC, 50 Hz, should be plugged into
a circuit rated for at least 6 amps.
Note: Do not use any detachable power cord that is not
adequately rated for the unit.
Installation of SPD210
Figure 1. Rear View of System
Table 1. Contents
Qty. Description
1Thermo Scientific Savant SpeedVac™ SPD210
Concentrator
1Cover Lock Emergency Release Tool
1Line Cord
1.To prevent damage to pump due to vapor exposures from sample solvent and to extend pump life, a vapor trap that condenses and traps vapors must be
placed in line between the SpeedVac™ concentrator and vacuum pump. We offer integrated universal vacuum systems (integrated vapor trap with the
vacuum pump) or component vacuum system (vapor trap plus vacuum pump).
CAUTION: Be sure to leave at least 4 inch
clearance on all sides of the unit. Overhead
clearance, equal to 19 inch (48 cm), is required
for raising the cover. Verify that the unit is on a
leveled and stable platform. If necessary, move
the unit to a more suitable location.
WARNING: Before connecting the unit to an
electrical outlet, make certain that voltage,
frequency, and amperage match the
requirements indicated on the product label,
name plate of the instrument. Use sockets with a
protective earth conductor and correct mains
cable.
CAUTION: Cold trap should be in line between
the vacuum source and the SPD Unit.
Vacuum Tubing
RVT5105
Refrigerated Vapor
Trap
SPD210
Vacuum
Concentrator
VLP Vacuum Pump

SpeedVac™ SPD210 Operation | 5
Operation
Connect the power cord to the power inlet on the right side of
the unit and plug it into the appropriate outlet. Turn on the
main power switch located on the front of the unit in the lower
right to energize the unit. The safety lid locking mechanism on
the SPD210 will automatically disengage. Do not attempt to
open the lid unless the unit is plugged in.
Note: The SPD210 Concentrator is an important component
in a complete concentration system that should also include a
refrigerated vapor trap and a vacuum pump along with other
applicable accessories. Please refer to operating instructions
of each component for details on usage.
Rotor installation. Open the lid of the rotor chamber.
Visually align the pin on the drive shaft with the groove on the
bottom of the rotor. Carefully lower the rotor onto the drive
shaft. Rotate the rotor by hand to ensure alignment of the pin
with the groove. Secure the assembly by screwing the
retaining knob into the drive shaft above the rotor. Tighten it
firmly but not excessively.
Description Of Control Panel
1. Lid locked - Indicates if the lid of the concentrator is
locked or not. The indicator will be illuminated when
locked.
2. Program buttons - 3 programs that are modifiable.
Loading a program is achieved by pressing the
corresponding Program button. The following
parameters are automatically loaded onto the screen:
• Temperature set point
• Heat time
• Run time
Default Program Settings
The table 2 below shows the factory default values attributed
to the programs parameters.
CAUTION: Use appropriate Thermo Fisher
Scientific designed rotors recommended for the
product.
CAUTION: Load the rotor and close the lid.
Always balance rotor loads. An imbalanced rotor
causes vibration that will damage the system’s
bearings and equipment. Load the rotor
symmetrically. There need not be a tube in each
holder, but the load must be evenly distributed.
When using a rotor with aluminum tube holders,
insert all the tube holders.
134 5 10
11 12
267 8 9

6 | Operation SpeedVac™ SPD210
*When the temperature is set to “no”, the heat time is
defaulted to “0.00” while executing the run.
Saving a program is achieved by pressing and holding down
the corresponding Program button for 3 seconds. The
parameters displayed in the screen are stored into the
program and can be loaded for use at a later time.
3. Pre-Heat - Use to pre-heat the chamber to 45°C prior to
beginning a run or between runs. Once a run is initiated,
the pre-heat automatically stops.
Note that the pre-heat function is only enabled if the
temperature set point is different than “no”.
4. Temperature display - Indicates the set temperature or
the actual temperature during a run in °C. The
temperature set point can be set from 35°C to 65°C at a
5°C interval. In addition, it is possible to set the
temperature to “no”, which means that heating will not be
applied during the run. The temperature setting of “no”
can be reached under 35°C or over 65°C.
5. Time display - Indicates the heat timer or the run timer
set points. During a run, it indicates the elapsed or
remaining run time or the remaining heat time. The range
for these timers is from 0.01 [1 min.] to 9.59 [9 hours, 59
minutes] at a 1-minute interval. In addition, it is possible
to set the heat time to “CCC”, which represents a
continuous heating throughout the execution of a run.
The setting of “CCC” can be reached under 0.01 [1 min.]
or over 9.59 [9 hours, 59 minutes].
6. Select - Press this button to select the parameters to be
modified. The selection is from left to right, in a cyclic
manner. The selected parameters is shown by the
corresponding indicator that is illuminated.
7. Minus (“-”) - Decrements the value of the selected
parameter.
8. Plus (“+”) - Increments the value of the selected
parameter.
9. View - During a run, pressing view shows the set run
parameters. When no run is ongoing, pressing view
displays the actual live parameters. The time display
shows either “0.00” or the end status of the last executed
run (e.g. “End”, “Err.”).
10. Manual run - Starts a “Manual” run based on the
parameters loaded in the screen, use manual run
function if you do not want to set a fixed run time.
11. Auto run - Starts an “Automated” run based on the
parameters loaded in the screen, use auto run function if
you want to set a fixed run time.
12. Stop - Terminates a “Manual” or “Auto”run.
Note: Restoring the factory default parameters for a given
program is achieved by selecting it and then pressing and
holding down the Stop button for 3 seconds. The default
parameters associated with the program (factory default) will
be restored and the screen updated accordingly.
Audible Notification
The concentrator will play tones depending on the user
actions. Below is a description of these tones.
Table 2. Program Settings
Program Description Default UI
parameters
Program 1 Water
Temperature: 45°C
Heat time: 2.00
Run time: 2.00
Program 2 “Low Boiling”
ACN/MEOH
Temperature: 65°C
Heat time: 2.00
Run time: 2.00
Program 3
HPLC
H2O + Low Boil
solvent +.1% acid
Temperature: “no”
Heat time: 0.01*
Run time: 2.00
Note: The programs are for convenience only.
Prior to use, users are advised to conduct a risk
assessment to confirm that the program
parameters meet the user’s application specific
needs and conditions. Users accept the risks
associated with using these programs.
Table 3. Audible Notifications
Event Sound Description
Start-up 5 beeps
Starting a run (manual
or automatic) 1 single beep
Manually stopping a
manual or automatic
run
3 beeps
Automatically
stopping an automatic
run
1 beep that is repeated until the
user pushes the Stop button or
opens the cover of the
concentrator
Program saved 3 beeps
User input error 1 long beep that lasts for 1
second

SpeedVac™ SPD210 Operation | 7
Manual Run
1. Connect the unit to its required voltage.
2. Turn the power switch located on the front of the UNIT, to
the ON position, (light on switch indicates ON). The cover
lock disengages, allowing the top cover to be opened.
The display lights up and shows the following in
sequence:
• Name of the concentrator
• Software revision number
• Default values:
- Temperature 35°C
- Run Time 2.00 hours
- Heat Time 2.00 hour
3. Select a run configuration using one of the following
methods:
• Load a program
• Directly modify values that are loaded on the screen,
using the Select button and the “+”/ “-” buttons.
4. Set the temperature set point between 35°C and 65°C,
or “no”, for no heat.
5. Using the Select button and the “+”/ “-” buttons select
and modify “Heat Time” to between 0.01 and 9.59 hours
or “CCC” (for continuous heating). When the heat timer
expires, the heater will shut off, no matter what the
temperature set point reads (except if “CCC”).
6. Select Run Time: Since this is a manual run, no time
adjustment is needed.
7. Place sample tubes in rotor so load is balanced. Secure
rotor with the supplied knob (hand tight). Close cover.
8. Pre-heat may be selected at this time, to apply a 45°C
heat to the chamber.
9. Press the Manual Run button. The cover locks and the
lid locked indicator is illuminated. The rotor starts
spinning. The “Run Time” display counts up. The
temperature rises to the set temperature. The “Heat
Time” will count down if set point is not set to “CCC” and
if the temperature set point is not “no”. The vacuum will
be applied to the chamber.
Note: If the cover is not closed, the display will show “Lid”
and the run will not start.
10. To end the manual run, press Stop button. The unit will
sound three audible beeps. The display will show “End”,
the valves will click, allowing air to bleed into the
chamber.
11. After the rotor stops spinning, the cover lock disengages
and the lid locked indicator is turned off. The display
reverts to last set parameters.
12. Open the cover and remove the samples.
GENERAL: During the run, display shows actual parameters.
To check set parameters, press View button and Select
button. The display will revert temporarily to the set points for
approximately 5 seconds.
Auto Run
1. Refer to the Manual Run section for start-up.
2. To execute an AUTO “TIMED” RUN, use the Select
button and the “+”/ “-” buttons to select and modify the
Temperature, “Heat Time” and “Run Time” parameters.
The Run and Heat Time can be set from 0.01 to 9.59
hours (Heat Time also has “CCC” for continuous use).
3. Place the sample tubes in the rotor so that the load is
balanced. Secure the rotor with the supplied knob (hand
tight). Close the cover.
a. Press the Auto Run button to start the run. The
cover locks and the lid locked indicator is lit. The rotor
starts spinning. The run time display is counting
down in 1 minute Intervals. The heat time is counting
down if the set point is not set to “CCC” and if the
temperature set point is not set to “no” (use the
select button to view “Heat Time”). The temperature
rises in 1°C increments to set temperature. The
vacuum is applied to the chamber.
b. Once the time decrements to 0.00 Hours, the run will
automatically stop, the display will show “End”, the
valve will click, allowing air to bleed into the chamber.
The unit will sound 1 beep that will be repeated until
the user acts on it.
System error
1 long beep that lasts for 1
second and that is repeated
until the user pushes the Stop
button or opens the cover of the
concentrator
Note: The pre-heating function requires the
temperature set point to be different than “no” and
requires the lid to be closed.
Table 3. Audible Notifications
Note: If the cover is not closed, the display will
show “Lid” and the run will not start.