Thermo Scientific SpeedVac SRF110 User manual

SpeedVac™ SRF110
Refrigerated Vacuum Concentrator
Installation and Operation Manual
80302318 • Revision A • 7/16/2021

IMPORTANT Read this Installation and Operation Manual. Failure to follow the instructions in this manual can
result in damage to the product, injury to operating personnel, and poor equipment performance.
CAUTION All internal adjustments and maintenance must be performed by qualified service personnel.
DISCLAIMER Thermo Fisher Scientific Inc. does not accept any responsibility for any damage caused to its
products by unauthorized personnel.
Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to use in the
product operation. This document is copyright protected and any reproduction of the whole or any part of this
document is strictly prohibited, except with the written authorization of Thermo Fisher Scientific Inc.
The contents of this document are subject to change without notice. All technical information in this document
is for reference purposes only. System configurations and specifications in this document supersede all
previous information received by the purchaser.
© 2021 Thermo Fisher Scientific Inc. All rights reserved.

Contents
Introduction ................................................................. 1
Safety Considerations .................................................. 2
Operating Standards.................................................... 3
Product Specifications ............................................. 3
Environmental Conditions......................................... 4
Installation.................................................................... 5
Unpacking................................................................ 5
Installation of SRF110 .............................................. 5
Operation..................................................................... 7
Description of Control Panel..................................... 8
Operating the SRF110 ............................................. 9
Emergency Access into the Chamber....................... 10
Vacuum Pump Requirements................................... 11
Maintenance and Care................................................. 12
Troubleshooting........................................................... 13
Appendix ..................................................................... 15
Appendix A: Rotor and Accessory List
and Description........................................................ 15
Appendix B: Configuring SpeedVac Setup ............... 17
Appendix C: Installed configuration Diagrams........... 18
Appendix D: Chemical Resistance............................ 20
Warranty...................................................................... 21

WEEE Compliance ...................................................... 22
Contact Information .................................................... 23

SpeedVac™ SRF110 Refrigerated Vacuum Concentrator Introduction | 1
Introduction
The Thermo Scientific SpeedVac™ SRF110 is a dedicated
centrifugal vacuum concentration system for drying heat
sensitive samples such as Proteins, Enzymes and DNA/RNA.
SRF110 SpeedVac combines centrifugal force with vacuum
for efficient sample drying.
SRF110 SpeedVac Concentrator combines a refrigeration
system that cools to –4°C with a heater that warms to
+100°C to reach user defined temperatures. The operator
can select the drying temperature from –4°C to 100°C
(24.8°F to 212°F), in 1°C increments.
The SRF110 is a Refrigerated Concentrator that helps to
protect samples that may be sensitive to heat during the
evaporation process. Samples widely used in Proteomics,
Drug Discovery, Forensics, Food & Beverage, and Molecular
Biology applications that must be processed & preserved at
cooler temperatures. This method is often preferred to over
freeze drying in applications where samples are affected by
the freeze and thaw process. SRF110 features programming
capability to refrigerate sample post processing an assurance
that samples will not degrade due to heat.
The unique advantage of this Concentrator is that it may be
cooled to –4°C to prevent damage to heat labile samples.
For faster evaporation, the Concentrator is equipped with a
300 watt heater to warm the chamber during processing. The
Concentrator may be placed on a benchtop or another
laboratory work surface.

2 | Safety Considerations SpeedVac™ SRF110 Refrigerated Vacuum Concentrator
Safety Considerations
In this manual, the following symbols and conventions are
used.
Below are important safety precautions that apply to this
product.
This symbol when used alone indicates important
operating instructions which reduce the risk of
injury or poor performance of the unit.
CAUTION: This symbol in the context of a
CAUTION, indicates a potentially hazardous
situation which if not avoided could result in
minor to moderate injury or damage to the
equipment.
WARNING: This symbol in the context of a
WARNING, indicates potentially hazardous
situations which if not avoided could result in
serious injury or death.
This symbol indicates situations where
dangerous voltages exist and potential for
electrical shock is present.
The snowflake symbol indicates low
temperatures and risk of frost bite. Do not touch
bare metal or samples with unprotected body
parts.
CAUTION: This symbol indicates possible pinch
points which may cause personal injury.
This symbol indicates a need to use gloves during
the indicated procedures. If performing
decontamination procedures, use chemically
resistant gloves.
WARNING: Before installing, using or
maintaining this product, be sure to read the
manual and product warning labels carefully.
Failure to follow these instructions may cause the
product to malfunction, which could result in
injury or damage.
CAUTION: This symbol represents protective
conductor terminal.
CAUTION: Use this product only in the way
described in the product literature and in this
manual. Before using it, verify that this product is
suitable for its intended use. If the equipment is
used in a manner not specified by the
manufacturer, the protection provided by the
equipment may be impaired.
WARNING: Your unit must be properly grounded
in conformity with national and local electrical
codes. Do not connect the unit to overloaded
power sources.
WARNING: Disconnect the unit from all power
sources before cleaning, troubleshooting, or
performing other maintenance on the product or
its controls.
WARNING: Do not use this device in radioactive,
highly reactive or explosive atmosphere.
Do not use this device to process any explosive,
radioactive, highly reactive or explosive
atmosphere creating substances.
WARNING: Unauthorized repair of your unit will
invalidate your warranty. Contact Technical
Service at 1-866-984-3766 for additional
information.
CAUTION: Keep hands, hair and clothing clear
of way of lid closing.
Do not drop cover, close gently.
Do not lift the cover until rotor has stopped.
Do not operate with unbalanced load.
CAUTION: Solvents may be flammable.
Evaporate only non flammable or group D
solvents with autoignition temperature 180°C or
higher. Keep source of ignition away from
solvents.
WARNING: Solvents used in this product can
cause skin, eye, respiratory and digestive system
disorders. Locate this product inside a fume
hood.

SpeedVac™ SRF110 Refrigerated Vacuum Concentrator Operating Standards | 3
Operating Standards
Product Specifications
*Dependent upon ambient temperature, line voltage fluctuation, and load capacity.
Agency Approvals
Description Specifications
Operative Power* 115 VAC; 60 Hz; 12 Amps
230 VAC; 50/60 Hz; 6 Amps
Vacuum Chamber Epoxy coated Aluminum chamber
Chamber Seal Phenol-free lid gasket
Cover Epoxy coated Aluminum cover - includes a safety interlock
Induction Motor Maintenance free
Bearings Standard
Chamber temperature –4°C to 100°C (24.8°F to 212°F), 1°C increments
Weight 95 lbs (43 kg)
Dimensions (W x D x H) 16.62 in x 25 in x 13.75 in
(42.21 cm x 64 cm x 34.92 cm)
Fuse For 115V Models:
1. 20 Amp NEMA 5-20P plug
For 230 V 50 / 60 Hz Models:
1. NEMA 6-20P plug for use in the United States
2. PS1363 plug for use in the UK
3. CHI-10P plug for use in China or CEE7/7 plug for use in EU
IP Rating IP 20
Compliance &
Certification SRF110-115 SRF110-230
International UL CE, KC, RCM, UKCA
Refrigerant Compliance Complies to SNAP requirements Complies to F-Gas
requirements

4 | Operating Standards SpeedVac™ SRF110 Refrigerated Vacuum Concentrator
Environmental Conditions
These units are designed to operate Indoor only in the
absence of hoarfrost, dew, percolating water, rain and solar
radiation in a Pollution Degree 2 and Over voltage Category II
environment.
• Maximum altitude: 2000 meters above mean sea level
• Ambient temperature range: 5°C to 40°C (41°F to 104°F)
• Humidity: 80% for temperatures up to 31°C (88°F),
decreasing linearly to 50% relative humidity at 40°C
(104°F)
• Main supply voltage fluctuations not to exceed ±10% of
the nominal voltage.

SpeedVac™ SRF110 Refrigerated Vacuum Concentrator Installation | 5
Installation
Unpacking
Open the shipping cartons. Carefully remove the instrument
and accessories. Lift and carry with two people, holding
securely underneath with both hands. Use proper lifting
technique (lift with the legs, not the back) to avoid personal
injury. Compare the contents with the packing list. If there is a
discrepancy, call Thermo Scientific technical service.
List Of Contents
Inspection
Inspect the unit and accessories for damage that may have
occurred during shipment. Should there be any damage,
report it to the carrier and contact Thermo Scientific
immediately. Make sure the carrier inspects the damage and
leaves an inspection report. Register any claims for shipping
damage against the carrier or his agent. Save the shipping
carton in the event a return is necessary. Call Thermo
Scientific technical service for further assistance.
Site Preparation
The SRF110 requires a stable surface that is clean, dry, level,
and within 4 feet (1.2 meters) of a compatible electrical outlet.
Place the unit in a convenient location with access to a
vacuum source and a vapor trap.
The SRF110 units configured for 115 VAC, 60 Hz, should be
plugged into a circuit rated for at least 20 Amps. The SRF110
units configured for 230 VAC, 50 Hz, should be plugged into
a circuit rated for at least 8 Amps.
Installation of SRF110
Figure 1. SRF110 Installation
Place the SRF110 unit & other components depending upon
on ordered kit and place as shown in Figure 1. Leave at least
6-inch clearance on all sides of the units. This placement
helps to optimize for better refrigeration performance.
S No. Description Qty
1 Thermo Scientific SpeedVac™ SRF110
Concentrator
01
2 Line Cord 01
3 RF132 - Hexagonal Micro Centrifuge
Rotor
01
CAUTION: For better air circulation, be sure to
leave at least 6-inch clearance on all sides of the
unit. Overhead clearance, equal to 18 inch
(46 cm), is required for raising the cover. Verify
that the unit is on a leveled and stable platform. If
necessary, move the unit to a more suitable
location.
WARNING: Before connecting the unit to an
electrical outlet, make certain that voltage,
frequency, and amperage match the
requirements indicated on the product label,
name plate of the instrument. Use sockets with a
protective earth conductor and correct mains
cable.
Note: Do not use any detachable power cord that is not
adequately rated for the unit.
CAUTION: Cold trap should be in line between
the vacuum source and the SRF Unit.

6 | Installation SpeedVac™ SRF110 Refrigerated Vacuum Concentrator
To prevent damage to pump due to vapor exposures from
sample solvent and to extend pump life, a vapor trap that
condenses and traps vapors must be placed in line between
the SpeedVac Concentrator and Vacuum Pump.
After the components placement, connect the system
together using the Tubing set provided with kit. Connect the
system based on kit ordered. For connection details &
component details of each kit see, .
If the accessory Secondary Trap (SCT 120) is not used,
attach the other end of the tube to the inlet port on the
Vacuum Pump. If the accessory Secondary Trap (SCT 120) is
used, install the Secondary Trap as explained in Optional
Post-Secondary Trap. Then attach the tube from the Cold
Trap Cover to the “IN” connector on the Secondary Trap.
Attach another tube from the remaining connector on the
Secondary Trap (SCT 120) to the outlet port on the vacuum.
Electrical Connection
Connect the power cord to the power inlet on the back of the
unit and plug it into the appropriate outlet. Turn on the main
power switch located on the front of the unit in the lower right
to energize the unit. The safety lid locking mechanism on the
SRF110 will automatically disengage. Do not attempt to open
the lid unless the unit is plugged in.
The SRF110 Refrigerated Concentrator requires a dedicated
grounded electrical outlet. This outlet requires a 20 Amp
circuit breaker or fuse for models rated at 115 V (60 Hz). An
8 Amp circuit breaker or fuse is required for models rated at
230 V (50/60 Hz). 115 V models are equipped with a 20 Amp
NEMA 5-20P plug. 230 V models are available with a PS1363
plug for use in the UK or a CHI-10P plug for use in China or a
CEE7/7 plug for use in the EU. If this does not match with the
available receptacle, remove this plug and replace it with an
approved plug of the suitable style.
It is recommended that an emergency switch for
disconnecting the mains in the case of a malfunction is
located remote from the SRF110. It should be outside the
room in which the SRF110 is housed, or adjacent to the exit
from that room.
Rotor Installation
Open the lid of the rotor chamber. Carefully lower the rotor
onto the drive shaft. Place the rotor onto the shaft of the
Concentrator. Rotate the rotor slightly to engage the drive pin
in the shaft with the slots in the rotor hub. The top of the shaft
should be in line with the top of the rotor hub.
IMPORTANT NOTE: Do not use a rotor if it shows any signs
of damage. Failure of a spinning rotor could damage the
SRF110 or cause samples to be lost.
CAUTION: Use appropriate Thermo Fisher
Scientific designed rotors recommended for the
product. Use of non standard rotors may
damage the product.
CAUTION: Load the rotor and close the lid.
Always balance rotor loads. An imbalanced rotor
causes vibration that will damage the system’s
bearings and equipment. Load the rotor
symmetrically. There need not be a tube in each
holder, but the load must be evenly distributed.
When using a rotor with aluminum tube holders,
insert all the tube holders.