Beckman Coulter P/ACE MDQ User manual

A36419AC
March 2012
Instructions For Use
P/ACE MDQ
Installation & Maintenance
32 Karat 8.0
Beckman Coulter, Inc.
250 S. Kraemer Blvd.
Brea, CA 92821

P/ACE MDQ Installation & Maintenance
32 Karat 8.0
PN A36419AC (March 2012)
© 2012 Beckman Coulter, Inc.
All Rights Reserved
Printed in the USA
Made in the USA
Trademarks
BECKMAN COULTER, the stylized logo, P/ACE, 32 Karat,
and MDQ are trademarks of Beckman Coulter, Inc., and
are registered with the USPTO.
All other trademarks, service marks, products, or services
are trademarks or registered trademarks of their
respective holders.
Find us on the World Wide Web at:
www.beckmancoulter.com

Table of Contents
P/ACE MDQ Installation and Maintenance Manual iii
PN A36419AC
Section 1 Introduction
General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Section 2 Specifications and Site Requirements
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Section 3 Hardware and Software Installation
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5
Installation - General . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Unpacking and Repacking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Unpacking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6
Repacking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
Storage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
Installation - Hardware / Software . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Installing the GPIB Communication Interface Board . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Configuring the Computer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Power/Peripherals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
CMOS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Display . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Boot Control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
Installing the GPIB Communication Interface Board Driver . . . . . . . . . . . . . . . . . . . . 11
Installing the 32 Karat Software . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13
Software Licenses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Installing the Software License Key . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Changing the Network Name or Workstation Operating System . . . . . . . . . . . . . . . . . . 15
Installing the P/ACE MDQ Instrument . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
Installing the UV or PDA Detector/Capillary Cartridge . . . . . . . . . . . . . . . . . . . . . . . . . 16
Installing the Capillary Cartridge for UV/PDA Detectors . . . . . . . . . . . . . . . . . . . . . . . . . 19
Installing the LIF Detector . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Pre-installation Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Bench Space . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Installing the Interconnect Module . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Connecting the Laser Cable(s) to the Interconnect Module . . . . . . . . . . . . . . . . . . . . 21
Installing the LIF Detector Module . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
Installing Filters in the Filter Housing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
Installing the Filter Housing into the Detector . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
Installing the LIF Detector into the P/ACE MDQ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Preparing the Cartridge for LIF Usage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Installing the LIF Plug and Probe Stabilizer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
Connecting the Probe to the Clamping Bar . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26
Connecting the Computer to the P/ACE MDQ Instrument . . . . . . . . . . . . . . . . . . . . . . . 27
Analog Outputs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
PDA Detector Outputs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28

iv 32 Karat 8.0
PN A36419AC
UV Detector Outputs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28
LIF Detector Outputs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Configuring the System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Installing the Buffer/Sample Tray . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29
Installation - Additional Features . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Buffer Tray Reservoir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
External Detector Adapter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Section 4 Maintenance
Maintenance Procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Rebuilding the Capillary Cartridge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
Removing the Capillary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35
Replacing the Coolant Tubing and Seal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Marking the Capillary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42
Installing the Aperture Clip . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45
Trimming the Capillary Ends . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 48
Filling Vials and Installing Caps . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Filling 0.5 mL Vials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
Filling the 2.0 mL Vials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
Filling PCR Vials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
Filling the 96-Well Plates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52
Installing the UV Detector Wavelength Filters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 53
Calibrating the PDA Detector . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
Changing the Lamp . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58
Cleaning the Fiber Optics (UV and PDA Detectors) . . . . . . . . . . . . . . . . . . . . . . . . . . . 62
LIF Care and Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64
Inspecting the System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64
Cleaning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64
Storage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64
Calibrating the LIF Detector . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64
Accessing the LIF Calibration Wizard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64
Manual Calibration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
Auto Calibration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
Calibration Standard . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68
Capillary Diameter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68
Instrument Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69
Cleaning the Interface Block, Ejectors and Electrodes . . . . . . . . . . . . . . . . . . . . . . . . . . 71
Refilling the Coolant . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
Replacing the Electrodes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
Cleaning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
Replacement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
Replacing the Quad-Rings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76
Replacing the Fuses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77

P/ACE MDQ Installation and Maintenance Manual v
PN A36419AC
Section 5 Additional Features
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
Connecting Detectors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80
Connecting (Remote Start) Trigger Signals . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Trigger Start of Data Acquisition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Hold Off Injection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Stop Data Acquisition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Outputs 1 & 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Outputs 3 & 4 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Connecting External Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82
SS420X External Unit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83
Installing the SS420X External Device . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83
Connecting Detectors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83
Connecting Start Inputs (Trigger Signals) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84
Trigger Start of Data Acquisition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84
Hold Off Injection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84
Stop Data Acquisition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84
Outputs 1 & 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84
Outputs 3 through 8 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84
Connecting External Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 84
Configuring the SS420X External Device . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85
P/ACE™ MDQ External Detector Adapter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86
Safety . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86
Initial Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86
Installing the Capillary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 86
Installing the Capillary in the Standard Cartridge . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87
Installing the Capillary in the EDA-Only Cartridge . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88
Installing the Cartridge in the Instrument . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89
Programming for EDA Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 89
Connecting to an External Device . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90
Additional Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90
Parts List . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 90
P/ACE MDQ™ MDQ Buffer Reservoir Tray . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91
Filling the Tray . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91
Installing the Tray . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92
Programming the Tray . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 92
Solvent Compatibility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93
Parts List . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 93

vi 32 Karat 8.0
PN A36419AC

P/ACE MDQ Installation & Maintenance Manual
PN A36419AC vii
Warranty
Warranty
Subject to the exceptions and upon the conditions stated below, the Company warrants that the
products sold shall be free from defects in workmanship and materials for one year after delivery
of the products to the original Purchaser by the Company and if any such product should prove to
be defective within such one year period, the Company agrees, at its option, either (1) to correct
by repair or at the Company's election by replacement, any such defective product provided that
investigation and factory inspection discloses that such defect developed under normal and
proper use, or (2) to refund the purchase price.
The exceptions and conditions mentioned above are as follows:
a. Components or accessories manufactured by the Company which by their nature are
not intended to and will not function for one year are warranted only to give reasonable
service for a reasonable time. What constitutes a reasonable time and a reasonable
service shall be determined solely by the Company. A complete list of such
components and accessories is maintained at the factory.
b. The Company makes no warranty with respect to components or accessories not
manufactured by it. In the event of defect in any such component or accessory the
Company will give reasonable assistance to Purchaser in obtaining from the respective
manufacturer whatever adjustment is authorized by the manufacturer's own warranty.
c. Any component claimed to be defective must, if required by the Company, be returned
to the factory, transportation charges prepaid, and will be returned to Purchaser with
transportation charges collect unless the product is found to be defective, in which case
the Company will pay all transportation charges.
d. If the product is a reagent or the like, it is warranted only to conform to the quantity
and content and for the period (but not in excess of one year) stated on the label at the
time of delivery.
e. The Company may from time to time provide a special printed warranty with respect to
a certain product and where applicable, such warranty shall be deemed incorporated
herein by reference.
IT IS EXPRESSLY AGREED THAT THE ABOVE WARRANTY SHALL BE IN LIEU OF
ALL WARRANTIES OF FITNESS AND OF THE WARRANTY OF MERCHANTABILITY
AND THAT THE COMPANY SHALL HAVE NO LIABILITY FOR SPECIAL OR
CONSEQUENTIAL DAMAGES OF ANY KIND OR FROM ANY CAUSE WHATSOEVER
ARISING OUT OF THE MANUFACTURE, USE, SALE, HANDLING, REPAIR,
MAINTENANCE, OR REPLACEMENT OF ANY OF THE PRODUCTS SOLD.
Representations and warranties made by any person, including dealers and representatives of the
Company, which are inconsistent or in conflict with the terms of this warranty, shall not be
binding upon the Company unless reduced in writing and approved by an expressly authorized
officer of the Company.

32 Karat 8.0
PN A36419AC
viii
Warranty

P/ACE MDQ Installation & Maintenance Manual
PN A36419AC ix
Safety Information
Safety Information
This section provides safety information and instructions for the hardware and accessories of the
system. It is broken down into the following subsections:
r Symbols
r Waste Management and Recycling
r Chemical and Biological Safety
r Electrical Safety
r Moving Parts Safety

32 Karat 8.0
PN A36419AC
x
Safety Information
Safety Symbols
Safety Symbols
The following information describes the notes and warnings used in this document. Beckman
Coulter recommends that you review this information before using the system.
WARNING Paragraphs marked by “WARNING” alert you of a potential hazard to your personal safety if you
do not adhere to the information stated within the paragraph.
CAUTION Paragraphs marked by “CAUTION” indicate that there is a potential danger of equipment damage.
IMPORTANT Paragraphs marked by “IMPORTANT” contain information about a possible software program
failure, draw attention to a specific software setting or point out that a loss of data may occur if information
stated within the paragraph is not adhered to or if procedures are executed incorrectly.
NOTE Paragraphs marked by “NOTE” contain supplemental or explanatory information concerning the
current topic or procedural step.
The symbols displayed below and on the instrument are reminders that all safety instructions
should be read and understood before installation, operation, maintenance, or repair to this
instrument is attempted.
CAUTION This icon accompanies text and/or other symbols dealing with potential
damage to equipment. When present, it indicates that there is a potential danger of
equipment damage, software program failure, or that a loss of data may occur if
information stated within the “CAUTION” paragraph is not adhered to or procedures
are executed incorrectly.
HIGH VOLTAGE Paragraphs marked by this symbol indicate that a potential hazard to
your personal safety exists from a high voltage source.
BIOHAZARD Paragraphs marked by this symbol indicate that a potential hazard to
your personal safety exists from a biological source.
LASER LIGHT Paragraphs marked by this symbol indicate that a potential hazard to
your personal safety exists from a laser source.
SHARP OBJECTS Paragraphs marked by this symbol indicate that a potential hazard
to your personal safety exists from unblunted corners or other appendages on the
outside or inside of the equipment.
HOT SURFACE Paragraphs marked by this symbol indicate that a potential hazard to
your personal safety exists from heated surfaces or other appendages on the outside
or inside of the equipment.

P/ACE MDQ Installation & Maintenance Manual
PN A36419AC xi
Safety Information
Waste Management and Recycling
Waste Management and Recycling
Chemical and Biological Safety
WARNING Normal operation of the system can involve the use of solvents and reagents that are toxic,
flammable, or biologically harmful.
PROTECTIVE EARTH OR GROUND TERMINAL This symbol identifies the location of
the protective earth or ground terminal lug on the equipment.
OFF POSITION OF PRINCIPAL POWER SWITCH This symbol graphically represents
the equipment main power push-button switch when it is in the off position.
ON POSITION OF PRINCIPAL POWER SWITCH This symbol graphically represents
the equipment main power push-button switch when it is in the on position.
This symbol is required in accordance with the Waste Electrical and
Electronic Equipment (WEEE) Directive of the European Union. The
presence of this marking on the product indicates that the device:
1. was put on the European Market after August 13, 2005 and
2. must not be discarded using the municipal waste collection system of
any member state of the European Union.
Customers must understand and follow all laws regarding the proper
decontamination and safe disposal of electrical equipment. Please contact
your dealer or local Beckman Coulter office for details on the take-back
program that will facilitate the proper collection, treatment, recovery,
recycling, and safe disposal of Beckman Coulter products bearing this
label.
A016608L.EPS
WARNING • Observe all precautionary information printed on the original solution
containers.
• Operate the system in the appropriate environment.
• Take all necessary precautions when using pathology or toxic materials to
prevent the generation of aerosols.
• Observe all applicable precautionary procedures when using flammable
solvents in or near the instrument.
• Wear appropriate laboratory attire, for example, safety glasses, gloves, lab
coat and breathing apparatus, when working with hazardous materials.
• Dispose of all waste solutions in a proper manner.

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Safety Information
Electrical Safety
Electrical Safety
To reduce risk of electrical shock, all devices employ a three-wire electrical cable and plug to
connect the equipment to earth ground.
r Ensure that the wall outlet receptacle is properly wired and earth grounded.
r DO NOT use a three-to-two wire plug adapter.
r DO NOT use a two-wire extension cord or a two-wire multiple-outlet power strip.
r Disconnect power to the system before performing maintenance.
r DO NOT remove any panels; panels should be removed only by qualified service personnel.
Moving Parts
Moving parts are limited to the sample handling system. Plate movement is safety interlocked
through the Sample Access Cover. To avoid injury due to moving parts, observe the following:
r Keep loose clothing and hair away from the plate area.
r Never attempt to physically restrict movement of the plate assembly.
WARNING A high voltage power supply is used with this instrument. Safety interlocks
disable high-voltage output while the capillary access cover is open and
remove the risk of shock while performing routine instrument functions.
However, removal of any panel may expose an individual to the possibility of
severe electrical shock and/or mechanical injury. For this reason, any service
requiring removal of a panel or otherwise overriding or disabling safety
interlocks must be done by Beckman Coulter personnel only.

P/ACE MDQ Installation & Maintenance Manual
PN A36419AC 1
Introduction
General Information 1
1Introduction
1.1 General Information
This guide includes details on where to find information on specification and site requirements,
installation and configuration of system hardware/software, maintenance (customer
performable), and installation of additional features (SS420X, EDA, etc.). The details can be
found following the appropriate sections as follows:
r Section 1 - Introduction
r Section 2 - Specifications & Site Requirements
r Section 3 - Hardware and Software Installation
r Section 4 - Maintenance
r Section 5 - Additional Features

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Introduction
General Information

P/ACE MDQ Installation & Maintenance Manual
PN A36419AC 3
Specifications and Site Requirements
Introduction 2
2Specifications and Site Requirements
2.1 Introduction
Specifications and Site Requirements are published in the P/ACE™ MDQ Pre-Installation
Guide. This guide is sent to the installation site prior to the actual system installation. The guide
provides information necessary to ensure a successful installation, e.g., environment, bench
space, power requirements, etc., as well as specifications for the instrument and associated
components.

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Specifications and Site Requirements
Introduction

P/ACE MDQ Installation & Maintenance Manual
PN A36419AC 5
Hardware and Software Installation
Introduction 3
3Hardware and Software Installation
3.1 Introduction
For initial installation, a Beckman Coulter Service Representative will install and configure your
system. This section includes procedures for hardware and software installation in case it
becomes necessary to relocate or reconfigure the instrument.
NOTE Initial installation by anyone other than an authorized Beckman Coulter representative invalidates any
warranty covering this instrument.
This section is organized into four topics. The table below lists these topics in the order that they
are presented.
Topic Description
Installation - General Introductory information including unpacking/repacking and
storage of the P/ACE MDQ instrument.
Installation - Hardware/Software Installing the system includes configuring the Computer,
installing the GPIB board and driver, installing 32 Karat™
Software, setting up the P/ACE MDQ instrument, details on
license repair, uninstalling the software license, reprocessing
the license, and information regarding software license
diskettes.
System Configuration Configuring system components.
Installation - Additional Features
(See “Additional Features” on page 79.)
Installing and configuring the SS420X device; installing the
Buffer Tray Reservoir and External Detector Adapter.

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Hardware and Software Installation
Installation - General
3.2 Installation - General
This section of the guide covers installation of hardware/software, system configuration, and
additional features.
Hardware/Software installation includes setting up the computer, installing the GPIB board and
its driver, installing the 32 Karat Software, and completing the process by setting up the P/ACE
MDQ instrument to include the type of detector and capillary cartridge required.
System configuration includes entering the information in the software to reflect the P/ACE
MDQ hardware installed.
The Windows XP operating system must be installed on the computer prior to installing the
GPIB board, its driver, and the 32 Karat Software.
Additional features provide details on installing and configuring such items as the Buffer Tray
Reservoir, the External Detector Adapter, and the SS420X device.
The Beckman Coulter Service Engineer will initially perform all the general installation and
configuring procedures. However, these procedures will be outlined in the following paragraphs
for reference purposes and for those installations where the customer provides the computer.
Unpacking and Repacking
The Beckman Coulter Service Representative will unpack the P/ACE MDQ and computer.
General unpacking and installation information is given here in case it becomes necessary to
relocate or reconfigure the instrument.
Unpacking
1. Inspect both the computer and P/ACE MDQ containers for obvious damage.
2. Remove both units from their respective shipping containers, then remove the protective
plastic covering. Also, remove any shipping hardware. Keep the shipping containers in case
you need to repack the instrument.

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PN A36419AC 7
Hardware and Software Installation
Installation - General 3
Figure 3.1 Location of Interlocking Devices Used During Shipping
CAUTION The P/ACE MDQ is heavy (155 lbs/70.5 kg). To avoid personal injury and/or possible damage to
the equipment if dropped, use at least two people to lift the instrument.
1. Lift the cartridge cover door at the front of the P/ACE MDQ.
2. Remove five interlocking devices from the carriage assemblies. Lift the carriage assemblies
to one side to remove the foam inserts beneath each assembly. Refer to Figure 3.1.
3. Note any damage or missing items and contact the shipping company or your sales
representative immediately.
4. Position the instrument and computer as shown in Figure 3.2
1. Inlet Carriage Assembly 3. Foam Inserts (5)
2. Outlet Carriage Assembly

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Hardware and Software Installation
Installation - General
.
Figure 3.2 Placement of Computer and P/ACE MDQ Instrument on Work Surface
Repacking
1. To prepare the P/ACE MDQ for relocation and/or shipment, replace the interlocking
devices previously removed.
2. Install the protective plastic covering on the P/ACE MDQ, then place it in the shipping
container. Cover any additional hardware and place in shipping container.
Storage
The P/ACE MDQ can be stored indefinitely at temperatures from 4°C to 40°C. It is not advisable
to store the instrument for long periods of time below 4°C or above 40°C. If the instrument is
colder or warmer, allow the instrument to warm or cool to within the operating temperature range
before turning the power on and beginning the warm-up period.
After power has been turned off for several hours or more, allow a recovery time of 1 hour
(minimum) to ensure stability. The lamp must be on for the warm-up period.
Refer to the information provided with the computer for storage recommendations.