Buchi Lyovapor L-300 User manual

LyovaporTM L-300
Operation Manual
1153869A en

Imprint
Product Identification:
Operation Manual (Original) LyovaporTM L-300
1153869
Publication date: 08.2017
BÜCHI Labortechnik AG
Meierseggstrasse 40
Postfach
CH-9230 Flawil 1
E-Mail: [email protected]
BUCHI reserves the right to make changes to the manual as deemed necessary in the light of experi-
ence, especially with respect to structure, illustrations and technical details.
This manual is copyrighted. Information from it may neither be reproduced, distributed, or used for com-
petitive purposes, nor made available to third parties. The manufacture of any component with the aid of
this manual without prior written agreement is also prohibited.

BÜCHI Labortechnik AG Contents
Operation Manual LyovaporTM L-300 iii
Table of contents
1 About this document...........................................................................................................7
1.1 Warning notices in this document........................................................................................................ 7
1.2 Symbols............................................................................................................................................... 7
1.2.1 Warning symbols .....................................................................................................................7
1.2.2 Mandatory directive symbols ...................................................................................................8
1.2.3 Other symbols..........................................................................................................................8
1.3 Available languages............................................................................................................................. 8
1.4 Trademarks.......................................................................................................................................... 8
1.5 Connected devices .............................................................................................................................. 8
2 Safety....................................................................................................................................9
2.1 Proper use ........................................................................................................................................... 9
2.2 Use other than that intended ............................................................................................................... 9
2.3 Staff qualification ................................................................................................................................. 9
2.4 Location of warning signs on the product .......................................................................................... 10
2.5 Residual risks .................................................................................................................................... 10
2.5.1 Glass and acrylic breakage.................................................................................................... 10
2.5.2 Faults during operation ..........................................................................................................11
2.5.3 Cold and hot surfaces............................................................................................................ 11
2.5.4 Low internal pressure............................................................................................................. 11
2.6 Personal protective equipment .......................................................................................................... 11
2.7 Modifications...................................................................................................................................... 11
3 Product description...........................................................................................................12
3.1 Description of function ....................................................................................................................... 12
3.1.1 Freezing phase ......................................................................................................................12
3.1.2 Main drying phase..................................................................................................................12
3.1.3 Secondary-drying phase........................................................................................................ 13
3.2 Configuration ..................................................................................................................................... 14
3.2.1 Front View..............................................................................................................................14
3.2.2 Rear view ...............................................................................................................................15
3.2.3 Side connections....................................................................................................................16
3.2.4 Control panel..........................................................................................................................16
3.2.5 Pro control panel....................................................................................................................17
3.3 Type plate.......................................................................................................................................... 17
3.4 Refrigerant Specification.................................................................................................................... 17
3.5 Specifications supplied ...................................................................................................................... 18
3.6 Technical data ................................................................................................................................... 18
3.6.1 Lyovapor™ L-300 ..................................................................................................................18
3.6.2 Ambient conditions.................................................................................................................19
3.6.3 Materials ................................................................................................................................19
4 Transport and storage ......................................................................................................20
4.1 Transport ........................................................................................................................................... 20
4.2 Storage .............................................................................................................................................. 20

Contents BÜCHI Labortechnik AG
iv Operation Manual LyovaporTM L-300
5 Installation..........................................................................................................................21
5.1 Installation site................................................................................................................................... 21
5.2 Putting the instrument in operation.................................................................................................... 22
5.2.1 Preparing the instrument........................................................................................................ 22
5.2.2 Establishing electrical connections ........................................................................................22
5.2.3 Fitting the fresh water connections ........................................................................................23
5.2.4 Fitting the drain tubes ............................................................................................................24
5.2.5 Connecting the coolant ..........................................................................................................25
5.2.6 Fitting pressure sensors (option) ...........................................................................................25
5.3 Commissioning the vacuum pump..................................................................................................... 27
5.4 Assembling the drying attachments................................................................................................... 27
5.4.1 Fitting the 300 mm dia. O-ring ...............................................................................................27
5.4.2 Fitting the acrylic drying chamber ..........................................................................................28
5.4.3 Fitting the manifold acrylic drying chamber............................................................................ 29
5.4.4 Fitting the stopper acrylic drying chamber .............................................................................30
5.4.5 Fitting heatable shelves .........................................................................................................32
5.4.6 Fitting the non-heatable shelf.................................................................................................35
5.4.7 Assembling the manifold drying rack .....................................................................................37
5.4.8 Assembling manifold valves................................................................................................... 37
5.5 Gas connections (option)................................................................................................................... 40
5.5.1 Fitting an air filter (option) ......................................................................................................40
5.5.2 Connecting inert gas (option).................................................................................................41
6 Operating the control panel..............................................................................................42
6.1 Layout of the control panel ................................................................................................................ 42
6.2 Function bar....................................................................................................................................... 42
6.3 Menu bar............................................................................................................................................ 43
6.3.1 Start menu .............................................................................................................................44
6.3.2 Favourites menu ....................................................................................................................44
6.3.3 Configuration menu................................................................................................................44
6.3.4 Messages menu.....................................................................................................................48
6.4 Status bar .......................................................................................................................................... 49
6.5 Carrying out freeze-drying ................................................................................................................. 50
6.5.1 Preparing the instrument........................................................................................................ 50
6.5.2 Starting freeze-drying............................................................................................................. 50
6.5.3 Editing parameters while the process is running ...................................................................51
6.5.4 Ending freeze-drying..............................................................................................................51
6.5.5 Shutting down the instrument ................................................................................................51

BÜCHI Labortechnik AG Contents
Operation Manual LyovaporTM L-300 v
7 Operating Pro control panel ............................................................................................. 53
7.1 Layout of Pro control panel................................................................................................................ 53
7.2 Function bar....................................................................................................................................... 53
7.3 Menu bar............................................................................................................................................ 55
7.3.1 Start menu .............................................................................................................................55
7.3.2 Favourites menu ....................................................................................................................55
7.3.3 Method menu......................................................................................................................... 56
7.3.4 Configuration menu................................................................................................................56
7.3.5 Messages menu.....................................................................................................................60
7.4 Status bar .......................................................................................................................................... 60
7.5 Editing a method................................................................................................................................ 62
7.5.1 Creating a new method..........................................................................................................62
7.5.2 Changing the name of a method............................................................................................62
7.5.3 Setting the sample collapse temperature............................................................................... 63
7.5.4 Setting the gas type ...............................................................................................................63
7.5.5 Setting the shelf loading temperature ....................................................................................63
7.5.6 Setting the steps of a method ................................................................................................64
7.5.7 Setting the phases of a method .............................................................................................65
7.6 Deleting a method.............................................................................................................................. 67
7.7 Setting end point definitions............................................................................................................... 67
7.7.1 Pressure difference test......................................................................................................... 67
7.7.2 Temperature difference test...................................................................................................69
7.7.3 Pressure rise test ...................................................................................................................70
7.8 Performing freeze-drying using a method [Pro control panel] ........................................................... 71
7.8.1 Preparing the instrument........................................................................................................ 71
7.8.2 Selecting a method ................................................................................................................71
7.8.3 Starting freeze-drying............................................................................................................. 72
7.8.4 Changing parameters while the process is running............................................................... 73
7.8.5 Ending freeze-drying..............................................................................................................73
7.8.6 Shutting down the instrument ................................................................................................73
7.9 Performing freeze-drying manually [Pro control panel]...................................................................... 73
7.9.1 Preparing the instrument........................................................................................................ 73
7.9.2 Starting freeze-drying............................................................................................................. 74
7.9.3 Editing parameters while the process is running ...................................................................74
7.9.4 End point definition ................................................................................................................75
7.9.5 Ending freeze-drying..............................................................................................................75
7.9.6 Shutting down the instrument ................................................................................................75
8 Mobile connection .............................................................................................................76
8.1 Setting up BUCHI Connect Solution.................................................................................................. 76
8.2 Handling data..................................................................................................................................... 76
8.3 Connecting the instrument to the LAN............................................................................................... 77
8.4 Requirements for local network settings............................................................................................ 77
8.5 Assigning a dynamic IP address........................................................................................................ 77
8.6 Enabling the control panel on the BUCHI Cloud................................................................................ 77
8.7 Downloading the BUCHI Monitor app................................................................................................ 77
8.8 Layout of BUCHI Monitor app............................................................................................................ 78
8.9 Connecting the instrument and app using a QR code....................................................................... 78
8.9.1 Generating a QR code........................................................................................................... 78
8.9.2 Scanning the QR code...........................................................................................................79
8.10 Connecting the instrument and app using a password...................................................................... 80
8.10.1 Generating a password..........................................................................................................80
8.10.2 Entering the password ...........................................................................................................80
8.11 Removing the instrument from the app.............................................................................................. 81
8.12 Enabling notifications......................................................................................................................... 81
8.13 Remotely retrieving process data ...................................................................................................... 82

Contents BÜCHI Labortechnik AG
vi Operation Manual LyovaporTM L-300
9 Cleaning and servicing .....................................................................................................83
9.1 Regular maintenance work................................................................................................................ 83
9.2 Performing a vacuum test.................................................................................................................. 84
9.3 Performing a leak test........................................................................................................................ 84
10 Help with faults ..................................................................................................................87
10.1 Troubleshooting................................................................................................................................. 87
10.2 Faults, possible causes and remedies............................................................................................... 87
11 Taking out of service and disposal..................................................................................88
11.1 Disposal............................................................................................................................................. 88
11.2 Returning the instrument ................................................................................................................... 88
12 Appendix ............................................................................................................................89
12.1 Spare parts and accessories ............................................................................................................. 89
12.1.1 Top-mount drying rack accessories....................................................................................... 89
12.1.2 Valve and sensor accessories ...............................................................................................91
12.1.3 Further accessories ...............................................................................................................92
12.1.4 Spare parts ............................................................................................................................92

BÜCHI Labortechnik AG About this document | 1
Operation Manual LyovaporTM L-300 7/96
1 About this document
These operating instructions for the Lyovapor™ L-300 are correct at the time sup-
plied. They are an integral part of the product and contain important information that
is necessary for safe operation and maintenance.
These operating instructions apply to all variants of the Lyovapor™ L-300.
uTo ensure safe and trouble-free operation, read these operating instructions be-
fore starting up the device and follow the guidance they contain.
uKeep the operating instructions somewhere near to the device.
uPass on the operating instructions to any subsequent owner or user.
BÜCHI Labortechnik AG accepts no liability whatsoever for any faults or damages
that result from the failure to follow these operating instructions.
uIf you still have any questions after reading these operating instructions, please
contact BÜCHI Labortechnik AG Customer Service. Contact details for your local
agents can be found on the back cover of these operating instructions or on the In-
ternet at http://www.buchi.com.
1.1 Warning notices in this document
Warning notices warn you of dangers that can occur when handling the device. There
are four danger levels, each identifiable by the signal word used.
Signal word Meaning
DANGER Indicates a danger with a high level of risk which could result in
death or serious injury if not prevented.
WARNING Indicates a danger with a medium level of risk which could result in
death or serious injury if not prevented.
CAUTION Indicates a danger with a low level of risk which could result in mi-
nor or medium-severity injury if not prevented.
IMPORTANT Indicates a danger that could result in damage to property.
1.2 Symbols
The following symbols may be displayed in this instruction manual or on the device:
1.2.1 Warning symbols
Symbol Meaning Symbol Meaning
General warning Corrosive substance
Dangerous electrical voltage Flammable substance
Biological hazard Potentially explosive atmos-
phere
Breakable items Dangerous gases

1 | About this document BÜCHI Labortechnik AG
8/96 Operation Manual LyovaporTM L-300
Symbol Meaning Symbol Meaning
Hot surface Health-harming or irritant
substances
Risk of hand injury Strong magnetism
1.2.2 Mandatory directive symbols
Symbol Meaning Symbol Meaning
Wear safety goggles Wear protective clothing
Wear protective gloves Heavy load, do not lift with-
out assistance
1.2.3 Other symbols
NOTE
This symbol draws attention to useful and important information.
RThis character draws attention to a requirement that must be met before the in-
structions below are carried out.
uThis character indicates an instruction that must be carried out by the user.
5This character indicates the result of a correctly carried out instruction.
1.3 Available languages
These operating instructions were originally produced in German and have been
translated into several other languages. The translations are available on the en-
closed CD or can be obtained as a PDF file via http://www.buchi.com.
1.4 Trademarks
Product names and registered or unregistered trademarks that are used in this in-
struction manual are used only for identification and remain the property of the owner
in each case.
1.5 Connected devices
In addition to these operating instructions, you should also follow the instructions and
specifications in the documentation for the connected devices.

BÜCHI Labortechnik AG Safety | 2
Operation Manual LyovaporTM L-300 9/96
2 Safety
2.1 Proper use
The Lyovapor™ L-300 is used for freeze-drying solid materials in ampoules, vials,
trays, round-neck or wide-neck flasks and is exclusively intended for that purpose.
The Lyovapor™ L-300 can be used in laboratories for the following tasks:
Sublimating and condensing water-based samples
Sublimating and condensing samples containing solvents
2.2 Use other than that intended
Use of any other kind than that described in the section Chapter2.1 "Proper use",
page9 and any application that does not comply with the technical specifications
(see Chapter3.6 "Technical data", page18) constitutes use other than that in-
tended.
In particular, the following applications are not permissible:
Use of the instrument in an environment with a potential risk of explosion or areas
which require explosion-safe apparatus.
Use of the instrument for processing substances outside of research and develop-
ment.
Production and processing of substances that can lead to spontaneous reactions,
such as explosives, metal hydrides or solvents that can form peroxides.
Processing with explosive gas mixtures.
Drying samples with high solvent concentrations without special safety precau-
tions.
Damage or hazards attributable to use of the product other than as intended are en-
tirely at the risk of the operator alone.
2.3 Staff qualification
Unqualified persons are unable to identify risks and are therefore exposed to greater
dangers.
The device may only be operated by suitably qualified laboratory staff.
These operating instructions are aimed at the following target groups:
Users
Users are persons that meet the following criteria:
They have been instructed in the use of the device.
They are familiar with the contents of these operating instructions and the applica-
ble safety regulations and apply them.
They are able on the basis of their training or professional experience to assess
the risks associated with the use of the device.

2 | Safety BÜCHI Labortechnik AG
10/96 Operation Manual LyovaporTM L-300
Operator
The operator (generally the laboratory manager) is responsible for the following as-
pects:
The device must be correctly installed, commissioned, operated and serviced.
Only suitably qualified staff may be assigned the task of performing the operations
described in these operating instructions.
The staff must comply with the local applicable requirements and regulations for
safe and hazard-conscious working practices.
Safety-related incidents that occur while using the device should be reported to the
manufacturer ([email protected]).
BUCHI service technicians
Service technicians authorized by BUCHI have attended special training courses and
are authorized by BÜCHI Labortechnik AG to carry out special servicing and repair
measures.
2.4 Location of warning signs on the product
The following warning symbols are present on the instrument.
Fig.1: Location of warning signs on the product
General warning
2.5 Residual risks
The device has been developed and manufactured using the latest technological ad-
vances. Nevertheless, risks to persons, property or the environment can arise if the
device is used incorrectly.
Appropriate warnings in this manual serve to alert the user to these residual dangers.
2.5.1 Glass and acrylic breakage
Broken glass and acrylic can cause severe cuts.
Damaged glass and acrylic components may implode if subjected to a vacuum.
Minor damage to the ground joints impairs the sealing effect and may therefore dimin-
ish sublimination capacity.
uHandle the flask and other glass and acrylic components carefully and do not drop
them.
uAlways place the flasks in a suitable holder when they are not mounted on the Ly-
ovapor™.

BÜCHI Labortechnik AG Safety | 2
Operation Manual LyovaporTM L-300 11/96
uAlways visually inspect glass and acrylic components for damage every time they
are to be used.
uDo not continue to use glass and acrylic components that are damaged.
uAlways wear protective gloves when disposing of broken glass and acrylic.
2.5.2 Faults during operation
If a device is damaged, sharp edges or exposed electrical wires can cause injuries.
uRegularly check device for visible damage.
uIf faults occur, switch off the device immediately, unplug the power cord and in-
form the operator.
uDo not continue to use devices that are damaged.
2.5.3 Cold and hot surfaces
The condenser coil and probes can be extremely cold. Heatable shelf areas can be
extremely hot. If touched, hot and cold surfaces can cause skin burns.
uDo not touch cold or hot surfaces or liquids and/or wear suitable protective gloves.
2.5.4 Low internal pressure
Evacuating the system reduces the pressure in the drying chamber. This reduced
pressure can cause glass and acrylic components to implode.
uMake sure that all glass and acrylic components are free of damage.
2.6 Personal protective equipment
Depending on the application, hazards due to heat and/or corrosive chemicals may
arise.
uAlways wear appropriate personal protective equipment such as safety goggles,
protective clothing and gloves.
uMake sure that the personal protective equipment meets the requirements of the
safety data sheets for all chemicals used.
2.7 Modifications
Unauthorized modifications may impair safety and lead to accidents.
uUse only genuine BUCHI accessories, spare parts and consumables.
uTechnical modifications to the device or accessories should only be carried out
with the prior written approval of BÜCHI Labortechnik AG and only by authorized
BUCHI technicians.
BUCHI accepts no liability whatsoever for damage arising as a result of unauthorized
modifications.

3 | Product description BÜCHI Labortechnik AG
12/96 Operation Manual LyovaporTM L-300
3 Product description
3.1 Description of function
The Lyovapor™ is a freeze-dryer in which frozen samples can be gently dried.
The basis of freeze-drying is sublimation. Sublimation refers to the process whereby a
substance transforms directly from the solid to the gaseous state.
The physical process of sublimation can be explained using the solvent water as an
example.
The water is frozen.
The frozen water is transformed into the gaseous state under vacuum at a pres-
sure below the triple point.
Thus, freeze-drying takes place in three phases:
1. Freezing phase: the sample is frozen at atmospheric pressure.
2. Main drying phase: heat is applied to the frozen sample under a vacuum. The
frozen water is removed by sublimation.
3. Secondary drying phase (only possible with heatable shelves): the trace lev-
els of water remaining are removed by heating.
The Lyovapor™ consists of an ice condenser and various top-mount drying racks.
The top-mount drying racks can be chosen to suit the availability of the sample being
dried and the requirements of the end product.
The following top-mount drying racks can be used:
Non-heatable and heatable shelves in rack
Trays in rack
Top-mount rack with manifold valves
3.1.1 Freezing phase
In the freezing phase, the liquid sample is transformed to a solid state. Freezing takes
place under atmospheric pressure using a separate freezer, a liquid nitrogen bath, or
a mixture of dry ice and alcohol.
The end of the freezing phase is reached as soon as the water or solvent contained in
the sample has fully crystallized.
3.1.2 Main drying phase
In the main drying phase, the ice crystals are removed from the sample by sublima-
tion. Sublimation in the Lyovapor™ takes place under a vacuum with the addition of
thermal energy.
The vacuum pressure is lowered to the level required for sublimation.
For water that is: less than 6.11mbar.
As the ice condenser is colder than the sample being dried, the vapour pressure in
the area of the ice condenser is lower than in the area of the sample. The water
vapour escaping from the sample therefore flows towards the ice condenser. The wa-
ter or solvent vapour condenses on the coil of the ice condenser.
If a manifold-valve rack is used, heat transfer takes place by convection and radiation
from the surroundings. Control of the thermal energy transferred is then difficult.
If using a drying chamber with heatable shelves, heat transfer takes place by direct
contact. The temperature of the heatable shelves is controllable. Control of the ther-
mal energy transferred is then possible.

BÜCHI Labortechnik AG Product description | 3
Operation Manual LyovaporTM L-300 13/96
Controlling the heat transfer prevents the following critical temperatures for amor-
phous and crystalline materials being reached:
the glass transition temperature Tg' of the frozen sample.
the collapse temperature Tc.
the eutectic temperature Teu.
Above the glass transition temperature and the collapse temperature, the viscosity of
the frozen sample decreases. The reduced viscosity leads to the collapse of the sam-
ple's matrix structure.
Above the eutectic temperature, the sample melts.
During the main drying phase, the product temperature must remain below the col-
lapse temperature for amorphous materials in the sample.
Sublimation of the ice crystals progresses downwards from the surface of the product.
Above the sublimation boundary, the product is dry ("freeze-dried cake"), while further
inside the product is still frozen.
The end of the main drying phase is reached when all ice crystals have been re-
moved from the sample.
After the main drying phase, the remaining fluid content in the sample can still be be-
tween 5 to 10%.
3.1.3 Secondary-drying phase
In the secondary drying phase, the unfrozen water is removed from the sample by
desorption. The secondary drying function is performed by the heatable shelves in the
drying chamber of the Lyovapor™.
In the secondary drying phase, the temperature of the heatable shelves is raised and
held for several hours.
The end of the secondary drying phase is reached when the residual moisture in the
sample is between 1% and 5%.

3 | Product description BÜCHI Labortechnik AG
14/96 Operation Manual LyovaporTM L-300
3.2 Configuration
3.2.1 Front View
6
5
8
9
4
3
2
1
7
Fig.2: Front view
1 Connections for heatable shelves
(Lyovapor™ L-300 Pro only)
2 Intermediate valve
3 Ice condenser 4 Optional mounting position for control
panel
5 Ventilation slots 6 Castors
7 Castor brake 8 On/Off master switch
9 Control panel

BÜCHI Labortechnik AG Product description | 3
Operation Manual LyovaporTM L-300 15/96
3.2.2 Rear view
7
6
4
5
11
12
14
15
13
3
2
1
10
98
Fig.3: Rear view
1 Power isolating switch 2 Type plate/Refrigerant specifications
3 Connections for pressure sensors
(option)
4 Side connections
5 Connection for fresh water 6 Connection for condensate drain
hose I
7 Connection for condensate drain
hose II
8 Ventilation slots
9 Gas connection for venting valve 10 Gas connection for pressure regulat-
ing valve
11 Coolant outlet connection 12 Coolant inlet connection
13 Vacuum connection 14 Power cord
15 Vacuum pump connection

3 | Product description BÜCHI Labortechnik AG
16/96 Operation Manual LyovaporTM L-300
3.2.3 Side connections
2
1
8
763
4
5
Fig.4: Side connections
1 Connection for pressure sensor
(option)
2 Connection for pressure sensor
(option)
3 Automatic stoppering connection 4 Connection for fresh water sensor
5 Connection for receiving vessel sen-
sor
6 Connection for external pressure sen-
sors
(option)
7 LAN port 8 COM port
3.2.4 Control panel
1
23
Fig.5: Control panel
1 View 2 Function buttons
3 Navigation control

BÜCHI Labortechnik AG Product description | 3
Operation Manual LyovaporTM L-300 17/96
3.2.5 Pro control panel
1
2
Fig.6: Pro control panel
1 Touch-screen display 2 Navigation control
3.3 Type plate
The type plate identifies the instrument. The type plate is located at the rear of the in-
strument.
Buchi Labortechnik AG
9230 Flawil / Switzerland
Type: L-xxx
SN: 10xxxxxxxx
Volt: xxx-xxx VAC
Frequ.: xx Hz
Power: xxxx W
Built: 20xx
Made in India
6
5
4
1
3
2
7
8
910 9
Fig.7: Type Plate
1 Company name and address 2 Instrument name
3 Serial number 4 Input voltage range
5 Frequency 6 Power consumption maximum
7 Year of manufacture 8 Product code
9 Approvals 10 Symbol for "Do not dispose of as
household waste"
3.4 Refrigerant Specification
The refrigerant details are at the back of the instrument.

3 | Product description BÜCHI Labortechnik AG
18/96 Operation Manual LyovaporTM L-300
Type: L-xxx xxHz
Cooling System Refrigerant: Rxxx
Filling: xxx g
Global Warming Potential (GWP): xx tCO2
3
1
2
4
Fig.8: Refrigerant details
1 Instrument name 2 Refrigerant details
3 Filling capacity 4 Global warming potential
3.5 Specifications supplied
NOTE
The scope of delivery depends of the configuration of the purchase order.
Accessories are delivered as per the purchase order, order confirmation, and deliv-
ery note.
Component Specifications
supplied
Lyovapor™ L-300 or
Lyovapor™ L-300 Pro
1
Operation Manual 1
Technical data sheet 1
Vacuum tubing 1
O-ring 300mm 2
Vacuum seal, ISO-KF 16 1
Vacuum seals, ISO-KF 25 2
Vacuum clamp, ISO-KF 16 1
Vacuum clamps, ISO-KF 25 2
Vacuum tubing adaptor, ISO-KF 16 to ISO-KF 25 1
3.6 Technical data
3.6.1 Lyovapor™ L-300
Specification L-300 for 50Hz L-300 for 60Hz
Dimensions without drying attach-
ments (W x D x H)
710 x 1000 x 900mm 710 x 1000 x 900mm
Weight 250kg 250kg
Power supply 3 x 380 - 400 VAC 3 x 208 - 220 VAC
Power consumption
(rated)
3500 W 3500 W
Power consumption
(maximum)
6000 W 6000 W
Lug 16 A 16 A
Frequency 50 Hz 60 Hz

BÜCHI Labortechnik AG Product description | 3
Operation Manual LyovaporTM L-300 19/96
Specification L-300 for 50Hz L-300 for 60Hz
Overvoltage category II II
Protection rating IP20 IP20
Pollution degree 2 2
Inlet water temperature 15 - 20 °C 15 - 20 °C
Inert gas pressure max. 2bar max. 2bar
Water pressure 2 - 5/6 bar 2 - 5/6 bar
Coolant flow rate 6 L/min 6 L/min
3.6.2 Ambient conditions
The Lyovapor™ may only be used in indoor areas.
Max. altitude above sea level 2000 m
Ambient temperature 15‒30°C (25°C)
No maximum performance above 25°C
Maximum relative humidity 80% for temperatures up to 30°C
Storage temperature max. 45 °C
3.6.3 Materials
Component Materials of construction
Lyovapor™ housing Steel 1.4301/304 with powder coating
Vacuum chamber and components Steel 1.4301/304
Main connector PMMA GS
Drying chamber tube and cover PMMA GS
Seals FKM
Manifold drying rack Steel 1.4301/304
Manifold valves Natural rubber, PP
Cooling medium circuit Copper for freezing applications
EN 12735-1
Steel 1.4301/304
Vacuum clips Aluminium
Condensate drain tube Silicone
Condensate drain and venting valve Brass with EPDM seal
Regulating valve EN 1.4301
PBT
Silicone
Steam generation EN 1.4301
EPDM seal
Silicone

4 | Transport and storage BÜCHI Labortechnik AG
20/96 Operation Manual LyovaporTM L-300
4 Transport and storage
4.1 Transport
IMPORTANT
Risk of breakage due to incorrect transportation
Make sure that the instrument is fully dismantled.
Pack every instrument components properly to prevent breakage. Use the original
packaging whenever possible.
Avoid sharp movements during transit.
uAfter transporting, check the instrument and all glass components for damage.
uDamage that has occurred in transit should be reported to the carrier.
uKeep packaging for future transportation.
4.2 Storage
uMake sure that the ambient conditions are complied with (see Chapter3.6 "Tech-
nical data", page18).
uWherever possible, store the device in its original packaging.
uAfter storage, check the device, all glass components, seals and tubing for dam-
age and replace if necessary.