Thermo Scientific iCAP Q User manual

Part of Thermo Fisher Scientific
Revision B - 1288090
Thermo Fisher Scientific
iCAP Q
Operating Manual

© 2012 Thermo Fisher Scientific Inc. All rights reserved.
Original Operating Instructions
Leybonol and Sogevac are a registered trademarks of Oerlikon Leybold Vacuum GmbH. Santoprene
is a registered trademark of Monsanto, Inc. Viton is a registered trademark of DuPont Dow
Elastomers.
All other trademarks are the property of Thermo Fisher Scientific Inc. and its subsidiaries.
Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to use
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any part of this document is strictly prohibited, except with the written authorization of Thermo
Fisher Scientific Inc.
Release History: Revision A released in March 2012.
Revision B released in June 2012.

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Thermo Fisher Scientific iCAP Q Operating Manual (P/N 1288090, Revision B) i
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ii iCAP Q Operating Manual (P/N 1288090, Revision B) Thermo Fisher Scientific

Thermo Fisher Scientific iCAP Q Operating Manual (P/N 1288090, Revision B) iii
Contents
Chapter 1 Using this Manual.....................................................................1-1
About this Manual ............................................................ 1-1
Typographical Conventions .............................................. 1-2
Signal Word................................................................... 1-2
Viewpoint Orientation................................................... 1-2
Data Input ..................................................................... 1-2
Topic Headings.............................................................. 1-3
Reference Documentation................................................. 1-4
Chapter 2 Scope of Delivery......................................................................2-1
Standard System Components .......................................... 2-1
Optional System Components .......................................... 2-2
Chapter 3 System Description...................................................................3-1
General Description.......................................................... 3-2
Instrument Layout ......................................................... 3-3
Sample Introduction System ............................................. 3-4
Peristaltic Pump............................................................. 3-4
Nebulizer ....................................................................... 3-5
Spray Chamber .............................................................. 3-5
Injector .......................................................................... 3-6
Torch............................................................................. 3-6
Interface............................................................................ 3-7
Sample Cone and Skimmer Cone .................................. 3-7
Extraction Lens .............................................................. 3-8
Ion Optics......................................................................... 3-9
RAPID Lens................................................................... 3-9
QCell............................................................................. 3-9
DA Assembly ............................................................... 3-10
Mass Analyzer ................................................................. 3-10
Quadrupole.................................................................. 3-10
Detector....................................................................... 3-10
Vacuum System .............................................................. 3-11
Forepump .................................................................... 3-12
Turbomolecular Pump................................................. 3-12
Pressure Measurement.................................................. 3-12
Gas Supply...................................................................... 3-13
Connections................................................................. 3-13
Plasma and Cooling Gas .............................................. 3-14
CCT Gas ..................................................................... 3-15
Additional Gas ............................................................. 3-17

Contents
iv iCAP Q Operating Manual (P/N 1288090, Revision B) Thermo Fisher Scientific
Cooling System............................................................... 3-19
Connections for Water Supply..................................... 3-19
Recirculating Chiller .................................................... 3-20
Exhaust System ............................................................... 3-21
Connections.................................................................... 3-22
Main Power Switch...................................................... 3-23
Power Connections ...................................................... 3-23
Fore Vacuum Pump Connections ................................ 3-24
Connection to Computer and Peripherals.................... 3-25
Chapter 4 Safety.......................................................................................... 4-1
Safety Symbols and Signal Words in this Manual.............. 4-2
Observing this Manual................................................... 4-2
Safety Symbols on the Instrument..................................... 4-3
Rating Plate....................................................................... 4-5
Intended Use..................................................................... 4-6
Qualified Personnel........................................................ 4-7
Permitted Materials........................................................... 4-7
Electrical Safety Precautions.............................................. 4-8
Residual Hazards............................................................... 4-9
Personal Protective Equipment ....................................... 4-10
EMC Information........................................................... 4-11
In Case of Emergency ..................................................... 4-12
Chapter 5 System Setup............................................................................. 5-1
Safety Guidelines for Installation....................................... 5-2
Placing the System ............................................................ 5-3
Instrument Dimensions ................................................. 5-3
Moving the Instrument.................................................. 5-4
Workbench for Instrument ............................................ 5-5
Laboratory Conditions...................................................... 5-7
Power Supply................................................................. 5-7
Gas Supply..................................................................... 5-7
Laboratory Temperature ................................................ 5-8
Humidity....................................................................... 5-8
Ventilation and Fume Exhaust....................................... 5-9
Vibration ....................................................................... 5-9
Airborne Noise Emission ............................................... 5-9
Chapter 6 Operation ................................................................................... 6-1
Safety Guidelines for Operation ........................................ 6-2
System Controls................................................................ 6-4
System Status LEDs ....................................................... 6-4
Power Panel ................................................................... 6-5
Starting Up the System ..................................................... 6-6
Shutting Down the System ............................................... 6-7
Switching to Standby Mode........................................... 6-7

Contents
Thermo Fisher Scientific iCAP Q Operating Manual (P/N 1288090, Revision B) v
Shutting Down the Complete System (Instrument
Vented).......................................................................... 6-7
Shutting Down the Instrument only (Instrument not
Vented).......................................................................... 6-8
Getting Ready................................................................... 6-9
Before Operating the System.......................................... 6-9
Getting Ready with the Experiment Editor .................... 6-9
Going to Operation Status with Instrument Control ... 6-13
Working with LabBooks ................................................. 6-14
Loading a LabBook ...................................................... 6-14
Submitting a LabBook ................................................. 6-15
Starting the Data Acquisition....................................... 6-15
After Operation............................................................... 6-16
Run the System with Blanks......................................... 6-16
Release Peristaltic Pump Tubing .................................. 6-16
Emptying the Waste Container.................................... 6-16
Chapter 7 Troubleshooting ........................................................................7-1
General Remarks............................................................... 7-2
Administrator/User ........................................................ 7-2
Safety Guidelines for Troubleshooting .............................. 7-2
Error Messages .................................................................. 7-4
Plasma not Lit................................................................... 7-5
Sensitivity Problems/No Signal ......................................... 7-7
Signal Drifts with Time .................................................... 7-8
Poor Signal Stability.......................................................... 7-9
Interlocks ........................................................................ 7-10
Door Lock ................................................................... 7-10
Interface Temperature.................................................. 7-10
Low Water Flow .......................................................... 7-10
Hardware Lock Open................................................... 7-11
Water Valve Closed...................................................... 7-11
Low Argon Pressure ..................................................... 7-11
Low Cool Gas Flow ..................................................... 7-11
Low Exhaust Gas Flow................................................. 7-12
Plasma Lit Sensor......................................................... 7-12
Chapter 8 Maintenance..............................................................................8-1
Safety Guidelines for Maintenance.................................... 8-2
General Advice for Maintenance ....................................... 8-4
Returning Parts.............................................................. 8-4
Servicing Plan ................................................................... 8-5
General Maintenance Routines ......................................... 8-7
Cleaning the Surface of the Instrument.......................... 8-7
Cleaning Agents............................................................. 8-7
Checking Warning Labels .............................................. 8-7
Checking Gas Lines for Leaks ........................................ 8-8
Maintaining the Air Filter ................................................. 8-9

Contents
vi iCAP Q Operating Manual (P/N 1288090, Revision B) Thermo Fisher Scientific
Maintaining the Inlet System .......................................... 8-11
Maintaining the Nebulizer ........................................... 8-11
Maintaining the Peristaltic Pump................................. 8-12
Maintaining the Spray Chamber .................................. 8-13
Maintaining the Injector .............................................. 8-14
Maintaining the Torch................................................. 8-15
Cleaning the Glassware ................................................ 8-16
Maintaining the Interface................................................ 8-17
Tools............................................................................ 8-17
Maintaining the Sample Cone...................................... 8-17
Maintaining the Skimmer Cone................................... 8-20
Maintaining the Extraction Lens.................................. 8-23
Thermo Fisher Scientific Service ..................................... 8-26
Health and Safety Form ............................................... 8-26
Services to be Performed by Thermo Fisher Scientific
Service Only................................................................. 8-26
Chapter 9 Additional Safety Information................................................ 9-1
Fore Vacuum Pump.......................................................... 9-2
Recirculating Chiller ......................................................... 9-4
Dionex ICS-5000.............................................................. 9-5
Legal Documents..................................................................... D-1
Glossary .................................................................................... G-1
Index ............................................................................................I-1

Thermo Fisher Scientific iCAP Q Operating Manual (P/N 1288090, Revision B) 1-1
Chapter 1 Using this Manual
This chapter provides information about this operating manual. It
contains the following topics:
•“About this Manual” on page 1-1
•“Typographical Conventions” on page 1-2
•“Reference Documentation” on page 1-4
About this Manual
This iCAP Q Operating Manual contains precautionary statements that
can prevent personal injury, instrument damage, and loss of data if
properly followed. It describes the modes of operation and principle
hardware components of your iCAP Q mass spectrometer and provides
step-by-step instructions for cleaning and maintaining your instrument.

Using this Manual
Typographical Conventions
1-2 iCAP Q Operating Manual (P/N 1288090, Revision B) Thermo Fisher Scientific
Typographical Conventions
This section describes typographical conventions that have been
established for Thermo Fisher Scientific manuals.
Signal Word
Make sure you follow the precautionary statements presented in this
manual. The special notices appear different from the main flow of text:
NOTICE Points out possible material damage and other important
information in connection with the instrument. ▲
Viewpoint Orientation
Left and right used in this manual always refer to the viewpoint of a
person facing the front side of the instrument.
Data Input
Throughout this manual, the following conventions indicate data input
and output via the computer:
•Messages displayed on the screen are represented by capitalizing the
initial letter of each word and by italicizing each word.
•Input that you enter by keyboard is identified by quotation marks:
single quotes for single characters, double quotes for strings.
•For brevity, expressions such as “choose File > Directories” are used
rather than “pull down the File menu and choose Directories.”
•Any command enclosed in angle brackets < > represents a single
keystroke. For example, “press <F1>” means press the key labeled
F1.
•Any command that requires pressing two or more keys
simultaneously is shown with a plus sign connecting the keys. For
example, “press <Shift> +<F1>” means press and hold the <Shift>
key and then press the <F1> key.
•Any button that you click on the screen is represented in bold face
letters. For example, “click Close”.