Agilent Technologies InfinityLab LC Series User manual

1260 Infinity II Flexible Pumps
Agilent InfinityLab LC Series
User Manual
1260 Infinity II Flexible Pump User Manual

1260 Infinity II Flexible Pump User Manual
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Document Information
Document No: SD-29000018 Rev. C
Edition: 6/2021
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© Agilent Technologies, Inc. 2021
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1260 Infinity II Flexible Pump User Manual 3
In This Guide...
This manual covers:
•Agilent 1260 Infinity II Flexible Pump (G7104C)
•Agilent 1260 Infinity II Bio Flexible Pump (G7131C)
1Introduction
This chapter gives an introduction to the module, instrument overview and internal
connectors.
2 Site Requirements and Specifications
This chapter provides information on environmental requirements, physical and
performance specifications.
3UsingtheModule
This chapter explains the operational parameters of the Agilent 1260 Infinity II
Flexible Pumps.
4PreparingthePump
This chapter provides information on how to set up the module for an analysis and
explains the basic settings.
5 How to Optimize the Performance of Your Module
This chapter gives hints on how to optimize the performance or use additional
devices.
6Troubleshootingand Diagnostics
Overview about the troubleshooting and diagnostic features.

1260 Infinity II Flexible Pump User Manual 4
7 Error Information
This chapter describes the meaning of error messages, and provides information
on probable causes and suggested actions how to recover from error conditions.
8 Maintenance
This chapter describes the maintenance of the Agilent 1260 Infinity II Flexible
Pumps.
9 Parts and Materials for Maintenance
This chapter provides information on parts for maintenance.
10 Identifying Cables
This chapter provides information on cables used with the modules.
11 Hardware Information
This chapter describes the pump in more detail on hardware and electronics.
12 LAN Configuration
This chapter provides information on connecting the module to the controller
software.
13 Appendix
This chapter provides additional information on safety, legal and web.

1260 Infinity II Flexible Pump User Manual 5
Contents
1Introduction9
Agilent 1260 Infinity II Flexible Pump 10
Agilent 1260 Infinity II Bio Flexible Pump 12
Operating Principle 14
Positions of the Multi Purpose Valve 16
Leak and Waste Handling 20
2 Site Requirements and Specifications 25
Site Requirements 26
Physical Specifications 29
Performance Specifications 31
3UsingtheModule37
Magnets 38
Turn on/off 39
Status Indicators 41
Best Practices 42
Flushing the Filter 50
Purging the Pump 53
Recommendations for Bio-Compatible and Bio-Inert System 55
Recommendations for Degassers 57
Solvent Information 58
Solvent Recommendation for Agilent 1290 Infinity and 1290 Infinity II and
1260 Infinity II Flexible Pumps 65
Algae Growth in HPLC Systems 70
Setting up the Pump with the Instrument Control Interface 71
Agilent Local Control Modules 83
4 Preparing the Pump 84
Capillary Coding Guide 85
Installing Capillaries 88

1260 Infinity II Flexible Pump User Manual 6
5 How to Optimize the Performance of Your Module 92
Delay Volume and Extra-Column Volume 93
How to Configure the Optimum Delay Volume 94
How to Achieve Higher Resolution 96
Using Solvent Calibration Tables 99
6 Troubleshooting and Diagnostics 105
User Interfaces 106
Agilent Lab Advisor Software 107
Pump Leak Rate Test 108
System Pressure Test 113
Pump Self Test 115
7 Error Information 119
What Are Error Messages 121
General Error Messages 122
Pump Error Messages 130
8 Maintenance 149
Introduction to Maintenance 151
Warnings and Cautions 153
Overview of Maintenance 154
Cleaning the Module 155
Install Fittings and Capillaries 156
Remove and Install Doors 157
Replace the Pressure Sensor 159
Replace the Inlet Weaver 161
Replace the Inlet Valve (G7104C) 163
Replace the Inlet Valve (G7131C) 164
Remove the Jet Weaver 165
Install the Jet Weaver 167
Replace the Seal Wash Pump Cartridge 169
Replace the Multi-Channel Gradient Valve (MCGV) 170
Replace the Four-Channel Gradient Valve (4CGV) 172

1260 Infinity II Flexible Pump User Manual 7
Release a Stuck Inlet Valve 174
Remove the Pump Head Assembly (G7104C) 176
Remove the Pump Head Assembly (G7131C) 178
Pump Head Maintenance (Tool Free) 181
Install the Pump Head Assembly (G7104C) 206
Install the Pump Head Assembly (G7131C) 208
Replace the Outlet Valve (G7104C) 210
Replace the Outlet Valve (G7131C) 213
Replace the Multipurpose Valve 215
Replace Parts of the Multipurpose Valve (G7104C) 217
Replace Parts of the Multipurpose Valve (G7131C) 218
Replace the High Pressure Outlet Filter or Filter Frit 219
Install the Inline Filter 221
Remove the Inline Filter 223
Replace Parts of the Inline Filter 224
Replace the Seal Wash Sensor 226
Replace the Module Firmware 228
Prepare the Pump Module for Transport 229
9 Parts and Materials for Maintenance 231
Overview of Main Assemblies (G7104C) 232
Overview of Main Assemblies (G7131C) 234
Flow Connections (G7104C) 236
Flow Connections (G7131C) 238
Pump Heads (G7104C) 240
Pump Heads (G7131C) 244
Multipurpose Valve (G7104C) 247
Multipurpose Valve (G7131C) 248
Cover Parts 249
Accessory Kit (G7104C) 250
Accessory Kit (G7131C) 251
Tool Kit 252

1260 Infinity II Flexible Pump User Manual 8
10 Identifying Cables 253
Cable Overview 254
Analog Cables 256
Remote Cables 258
CAN/LAN Cables 262
Agilent Module to PC 263
USB Cables 264
11 Hardware Information 265
Firmware Description 266
Electrical Connections 269
Interfaces 271
Setting the 8-bit Configuration Switch 276
Early Maintenance Feedback 279
Instrument Layout 280
12 LAN Configuration 281
What You Have To Do First 282
TCP/IP Parameter Configuration 283
Configuration Switch 284
Initialization Mode Selection 285
Dynamic Host Configuration Protocol (DHCP) 287
Link Configuration Selection 290
Manual Configuration 291
PC and User Interface Software Setup 296
13 Appendix 298
General Safety Information 299
Waste Electrical and Electronic Equipment Directive 305
Radio Interference 306
Sound Emission 307
Agilent Technologies on Internet 308

1260 Infinity II Flexible Pump User Manual 9
1Introduction
Agilent 1260 Infinity II Flexible Pump 10
Product Description 10
Features 11
Agilent 1260 Infinity II Bio Flexible Pump 12
Product Description 12
Features 13
Operating Principle 14
Positions of the Multi Purpose Valve 16
Leak and Waste Handling 20
Leak Sensor 23
Waste Concept 24
This chapter gives an introduction to the module, instrument overview and
internal connectors.

1Introduction
Agilent 1260 Infinity II Flexible Pump
1260 Infinity II Flexible Pump User Manual 10
Agilent 1260 Infinity II Flexible Pump
Product Description
The new Agilent 1260 Infinity II Flexible Pump improves your everyday efficiency
by combining the performance of a high-pressure mixing UHPLC pump with the
flexibility of a low-pressure mixing UHPLC pump.
The power range of 5 mL/min with a maximum pressure up to 800 bar allows to
run HPLC and UHPLC methods on the same LC system. Intelligent System
Emulation Technology enables the transfer from existing methods from different
LC systems - current Agilent systems as well as instruments from other
manufacturers.
The Agilent Inlet Weaver mixer, active damping, or the optional Agilent Jet
Weaver mixers for additional mixing capacity achieve high analytical efficiency.
The established multipurpose valve enhances laboratory efficiency by adding
useful functionalities, for example, mixer in/out switch, filter backflush, or
automatic purge.
BlendAssist software simplifies your workflow with accurate buffer/additive
blending.
Figure 1 Overview of the Flexible Pump
Status indicator
Pump head
MCGV
Inlet weaver
Power switch
Leak drain
Pressure sensor