Bruker SamplePro hr-MAS User manual

Version
Innovation with Integrity
NMR Spectroscopy
SamplePro hr-MAS
001
Sample Changer
User Manual

Copyright © by Bruker Corporation
All rights reserved. No part of this publication may be
reproduced, stored in a retrieval system, or transmitted, in any
form, or by any means without the prior consent of the publisher.
Product names used are trademarks or registered trademarks of
their respective holders.
This manual was written by
Gilbert Cyppel and Stanley J. Niles
© November 8, 2010: Bruker Biospin GmbH
Rheinstetten, Germany
P/N: Z31914
DWG-Nr.: Z4D11177
For further technical assistance on the SamplePro hr-MAS unit,
please do not hesitate to contact your nearest BRUKER dealer
or contact us directly at:
BRUKER BioSpin GMBH
am Silberstreifen
D-76287 Rheinstetten
Germany
Phone: + 49 721 5161 0
FAX: + 49 721 5171 01
E-mail: [e-mail]
Internet: www.bruker.com

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Table of Contents
Contents
1 About ..............................................................................................................7
1.1 This Manual.............................................................................................................. 7
1.2 Policy Statement ...................................................................................................... 7
1.3 Symbols and Conventions........................................................................................ 7
2 Introduction....................................................................................................9
2.1 Concept.................................................................................................................... 9
2.2 Limitations of Liability............................................................................................. 10
2.3 Copyright................................................................................................................ 10
2.4 Warranty Terms...................................................................................................... 10
2.5 Customer Service................................................................................................... 10
3 Safety............................................................................................................11
3.1 Intended Use..........................................................................................................11
3.2 Owner‘s Responsibility........................................................................................... 11
3.3 Personnel Requirements........................................................................................ 13
3.3.1 Qualifications.......................................................................................................... 13
3.3.2 Unauthorized Persons............................................................................................ 14
3.3.3 Instruction...............................................................................................................14
3.4 Personal Protective Equipment.............................................................................. 14
3.5 Basic Dangers........................................................................................................ 15
3.5.1 Location of the Robot ON/OFF Switch................................................................... 15
3.5.2 General Workplace Dangers.................................................................................. 16
3.6 Environmental Protection ....................................................................................... 19
3.7 Signage .................................................................................................................. 20
3.7.1 Warning Signs........................................................................................................ 20
4 Technical Data .............................................................................................21
4.1 General................................................................................................................... 21
4.2 Electrical................................................................................................................. 22
4.3 Operating Conditions.............................................................................................. 23
4.4 Rating Plate System............................................................................................... 23
4.5 Rating Plate Robot................................................................................................. 24
4.6 Rating Plate Exchange Unit ................................................................................... 24
5 Design and Function...................................................................................25
5.1 Overview ................................................................................................................ 25
5.2 Brief Description..................................................................................................... 26
5.3 System Description ................................................................................................ 26
5.4 Description of The SamplePro Robotic System ..................................................... 27
5.4.1 The Robot Back Panel ........................................................................................... 28
5.4.2 The SamplePro LED Status Light .......................................................................... 28

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5.4.3 The Door Lock........................................................................................................29
5.5 The SamplePro Exchange Unit..............................................................................29
5.5.1 Exchange Unit Back Panel.....................................................................................29
5.6 Description of the MAS Pneumatic Control Unit.....................................................31
5.6.1 COM Mode.............................................................................................................31
5.7 Description of the hr-MAS Probe............................................................................32
6 Transport, Packaging and Storage............................................................33
6.1 Symbols on the Packaging.....................................................................................33
6.2 Inspection at Delivery.............................................................................................35
6.3 Packaging...............................................................................................................36
6.4 Storage...................................................................................................................36
7 Installation and Initial Commissioning......................................................37
8 Operation Overview.....................................................................................39
8.1 Safety .....................................................................................................................39
8.1.1 Emergency Shutdown ............................................................................................39
8.2 General Operating Guidelines................................................................................40
8.2.1 Switching On the Device ........................................................................................40
8.2.2 Switching Off the Device ........................................................................................40
9 Assembling the Tray with Rotors ..............................................................41
10 Operation......................................................................................................45
10.1 SamplePro hr-MAS Main Display...........................................................................45
10.1.1 System View...........................................................................................................46
10.1.2 Holder View............................................................................................................47
10.1.3 Sample Holder List.................................................................................................48
10.1.4 Right Window Panel...............................................................................................48
10.1.4.1 Container Information.............................................................................................48
10.1.4.2 Robot Information...................................................................................................50
10.1.4.3 Exchange Unit Information.....................................................................................50
10.1.4.4 Nitrogen/Air Flow Information.................................................................................51
10.1.4.5 Cooling Temperature Information...........................................................................51
10.1.5 Menu and Button Navigation Overview..................................................................52
10.2 Basic Commands ...................................................................................................53
10.2.1 Insert Sample .........................................................................................................54
10.2.2 Eject Sample ..........................................................................................................55
10.3 Exchanging Rotors and rotor containers................................................................55
10.4 Activity History........................................................................................................56
11 Preventative Maintenance ..........................................................................59

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11.1 Safety..................................................................................................................... 59
11.1.1 Cleaning and Decontamination.............................................................................. 60
11.1.2 Weekly Maintenance.............................................................................................. 60
11.1.3 Cleaning and Lubrication........................................................................................ 60
11.1.3.1 Pickup Adapter and Object Sensor Z-racks ........................................................... 60
11.2 Cleaning the Outside of the SamplePro hr-MAS and Units.................................... 61
11.2.1 After Cleaning......................................................................................................... 61
11.2.2 Other Cleaning Operations..................................................................................... 61
11.3 Cleaning the Robot Barcode Reader ..................................................................... 61
12 Dismantling and Disposal...........................................................................63
12.1 Repair Declaration Form........................................................................................ 63
13 EC-Declaration of Conformity ....................................................................65
14 Contact .........................................................................................................67
Appendix A...........................................................................................................69
A.1 Warning Signs........................................................................................................ 69
A.2 Figures ................................................................................................................... 71
A.3 Tables..................................................................................................................... 73
A.4 Glossary ................................................................................................................. 75
A.5 Index.......................................................................................................................77

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1 About
1.1 This Manual
This manual enables safe and efficient handling of the device.
This manual is an integral part of the device, and must be kept in close proximity to the
device where it is permanently accessible to personnel.
Before starting any work, personnel must have read the manual thoroughly and under-
stood its contents. Compliance with all specified safety instructions and operating
instructions is vital to ensure safe operation.
In addition, local accident prevention regulations and general safety instructions must be
observed for the operational area of the device.
Illustrations in this manual are intended to facilitate basic understanding, and may differ
from the actual design.
This user manual must be kept with the device. In addition to the user manual, instruc-
tions concerning labor protection laws, operator regulations tools and supplies must be
available and adhered to.
1.2 Policy Statement
It is the policy of Bruker to improve products as new techniques and components
become available. Bruker reserves the right to change specifications at any time.
Every effort has been made to avoid errors in text and figure presentation in this publica-
tion. In order to produce useful and appropriate documentation, we welcome your com-
ments on this publication. Support engineers are advised to regularly check with Bruker
for updated information.
Bruker is committed to providing customers with inventive, high quality products and ser-
vices that are environmentally sound.
1.3 Symbols and Conventions
Safety instructions in this manual are marked with symbols. The safety instructions are
introduced using indicative words which express the extent of the hazard.
In order to avoid accidents, personal injury or damage to property, always observe safety
instructions and proceed with care.
DANGER
This combination of symbol and signal word indicates an immediately hazardous sit-
uation which could result in death or serious injury unless avoided.

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About
iThis symbol highlights useful tips and recommendations as well as information designed
to ensure efficient and smooth operation.
Special Safety Instructions
The following symbols are used in the safety instructions to draw attention to specific
danger:
WARNING
This combination of symbol and signal word indicates a potentially hazardous situa-
tion which could result in death or serious injury unless avoided.
CAUTION
This combination of symbol and signal word indicates a possibly hazardous situation
which could result in minor or slight injury unless avoided.
NOTICE
This combination of symbol and signal word indicates a possibly hazardous situation
which could result in damage to property or the environment unless avoided.
DANGER
This combination of symbol and signal word indicates dangers posed by electric
power. If the safety instructions are not observed, there is a danger of serious or fatal
injuries.

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2 Introduction
The SamplePro hr-MAS is a sample changer that was developed for high throughput,
high resolution, magic angle spinning (hr-MAS) applications, such as the measurement
of biological samples.
The new sample changer is part of a Bruker NMR system for standard NMR MAS appli-
cations and is used to transfer prepared MAS samples to and from Bruker NMR instru-
ments to ensure they stay in continuous operation.
2.1 Concept
The sample changer consists of a laboratory robot (SamplePro) and a transfer system
connecting the laboratory robot to the probe inside the NMR magnet.
The sample changer provides a Bruker standard interface, through which the changer
can be controlled from TopSpin and IconNMR software.
Refer to "Design and Function" on page 25 for a complete description of the design and
function of SamplePro hr-MAS.
Figure 2.1 SamplePro hr-MAS

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Introduction
2.2 Limitations of Liability
All specifications and instructions in this manual have been compiled taking account of
applicable standards and regulations, the current state of technology and the experience
and insights we have gained over the years.
The manufacturer accepts no liability for damage due to:
• Failure to observe this manual.
• Improper use.
• Deployment of untrained personnel.
• Unauthorized modifications.
• Technical modifications.
• Use of unauthorized spare parts.
The actual scope of supply may differ from the explanations and depictions in this man-
ual in the case of special designs, take-up of additional ordering options, or as a result of
the latest technical modifications.
The undertakings agreed in the supply contract, as well as the manufacturer's Terms
and Conditions and Terms of Delivery, and the legal regulations applicable at the time of
the conclusion of the contract shall apply.
2.3 Copyright
This manual is protected by copyright and intended solely for internal use.
This manual must not be made available to third parties, duplicated in any manner or
form – whether in whole or in part – and the content must not be used and/or communi-
cated, except for internal purposes, without the written consent of the manufacturer.
Violation of the copyright will result in legal action for damages. We reserve the right to
assert further claims.
2.4 Warranty Terms
The warranty terms are included in the manufacturer's Terms and Conditions.
2.5 Customer Service
Our customer service division is available to provide technical information. See "Con-
tact" on page 67 for contact details.
In addition, our employees are always interested in acquiring new information and expe-
rience gained from practical application; such information and experience may help
improve our products.