Ethicon DERMABOND PRINEO User guide

Application Guide
2. Remove the irst mesh patch from the mesh carrier
and dispose of the mesh carrier (Figure 1).
Flatten the mesh patch at the crease gently. Remove the
center section of the release backing paper from the mesh
(Figure 2).
Hold the mesh by the corners of the backing paper, ensuring
that the adhesive side of the mesh will be adhered to the
patient’s skin (Figure 3).
Pre-Application
1. Prior to applying DERMABOND PRINEO System (42 cm), ensure that the wound is clean, dry, and hemostatic. Close deep
layers such that there is no tension on the skin edges. The skin edges must be closely approximated prior to application
of the mesh, such that signiicant manual approximation is not required during mesh application.
Figure 3
Figure 2
Figure 1
DERMABOND® PRINEO® Skin Closure System (42 cm)
Do not use on patients with a known hypersensitivity to cyanoacrylate, formaldehyde, benzalkonium chloride, or pressure-sensitive adhesive.
Application highlights below.
For complete product details,
see Instructions for Use.

4. Gently pull the mesh perpendicularly over the incision
while adjusting with ingers or forceps to achieve skin
edge approximation and aix the remainder of the mesh
to the other side of the incision (Figure 5). If there are
areas where the mesh is loose, gently pass a gloved inger
or instrument over the aected area to ensure complete
adherence of the mesh to the skin.
Application
3. Position the mesh so one half is on either side of the
incision, ensuring approximately 1 cm of mesh extends
from the beginning of the incision (Figure 4).
Press gently to ensure intimate contact of the mesh
to the selected side of the incision.
6. Repeat Steps 2 and 3 using the second mesh patch.
ENSURE A MINIMUM MESH OVERLAP OF
APPROXIMATELY 1-5 CM BETWEEN THE FIRST
AND SECOND MESHES (Figure 7).
Trim mesh as necessary, ensuring at least 1 cm of the
mesh extends beyond the end of the incision (Figure 8).
7. Ensure that the meshes are in intimate contact
with the skin prior to application of the liquid
adhesive. If there are areas where the mesh is
loose or not adhered to skin, gently pass a
gloved inger or instrument over the aected
area to ensure complete adherence of the mesh
to the skin.
Application — Key Steps
5. Remove both paper backings/frames (Figure 6).
DO NOT APPLY LIQUID ADHESIVE UNTIL
THE SECOND MESH HAS BEEN DEPLOYED.
Figure 5
Figure 4
Figure 8
Figure 7
Figure 6

8. Apply liquid topical skin adhesive immediately after
applying the mesh*:
•Activate the liquid adhesive applicator by twisting
the purple dial until a snap is heard (Figure 9)
•Position the applicator tip straight down and away
from the application area. Pinch the tip of the applicator
and squeeze the lexible bulb one time. Once the
pressure in the bulb is released, it will partly or completely
ill with liquid adhesive (Figure 10). This primes the
applicator for dispensing the liquid adhesive
•Using short strokes and moving from one end of
the meshes to the other, spread the liquid adhesive
smoothly and evenly over the entire length of the
meshes and surrounding skin (Figure 11).
NOTE: DO NOT APPLY A SECOND COAT
*See Instructions for Use for full details.
Post-Application
9. Once applied to the meshes, the liquid adhesive will polymerize within approximately 60 seconds.
After 60 seconds, check that polymerization is complete by gently dabbing along the length of the
meshes with a gloved inger, checking for tackiness. When no liquid or tackiness is apparent, the
polymerization process is complete and the wound is closed and sealed.
Finally, inspect the incision for any blood or luid accumulation under the mesh, including areas where
luid may be seeping through the mesh, which could potentially impact the adherence to the skin.
If such areas exist, refer to full Instructions for Use.
For complete indications, contraindications, warnings, precautions, and adverse reactions,
please reference full package insert.
©2017 Ethicon US, LLC. All rights reserved. 080568170918
Figure 11
Figure 10
Figure 9