Milli-Q Millipore User manual

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User Manual
Milli-Q® Reference System

Milli-Q® Reference System 3
About this User Manual
Purpose
This User Manual is intended for use with a Milli-Q® Reference Water Purification
System.
This User Manual is a guide for use during the installation, normal operation and
maintenance of a Milli-Q® Reference Water Purification System. It is highly
recommended to completely read this manual and to fully comprehend its contents
before attempting installation, normal operation or maintenance of the Water
Purification System.
If this User Manual is not the correct one for your Water Purification System, then
please contact Millipore SAS.
Terminology
The term “Milli-Q® Reference Water Purification System” is replaced by the term
“System” for the remainder of this User Manual unless otherwise noted.
Document
FTPF11373 - V 2.0, 03/2013
About Millipore SAS
Internet Site
Address
The Internet site can be used to find addresses, telephone/fax numbers and other
information.
Internet Site Address:
www.millipore.com
www.millipore.com/techservice
www.millipore.com/lab_water
Manufacturing
Site
Millipore SAS
67120 Molsheim
FRANCE

4 Milli-Q® Reference System
Legal Information
Notice
The information in this document is subject to change without notice and should not be
construed as a commitment by Millipore SAS. Millipore SAS assumes no responsibility
for any errors that might appear in this document. This manual is believed to be
complete and accurate at the time of publication. In no event shall Millipore SAS be
liable for incidental or consequential damages in connection with or arising from the
use of this manual.
We manufacture and sell water purification systems designed to produce pure or ultra
pure water with specific characteristics (µS/cm, T, TOC, CFU/ml, Eu/ml) when it leaves
the water purification system provided that it’s fed with water quality within
specifications, and properly maintained as required by the supplier.
We do not warrant these systems for any specific applications. It is up to the end user
to determine if the quality of the water produced by our systems matches his
expectations, fits with norms/legal requirements and to bear responsibility resulting
from the usage of the water.
Product
warranty and
limitation of
liability
The applicable warranty and limitation of liability for the products listed in this
publication may be found at http://www.millipore.com/ec/cp3/terms within the "Terms
and Conditions of Sale" applicable to your purchase transaction.
Trademarks
Elix, Q-Gard, Quantum, Milli-Q, BioPak, EDS-Pak, Millipak and Millipak Express are
registered trademarks of Merck KGaA, Darmstadt, Germany.
Millipore, the “M” logo and RiOs are trademarks of Merck KGaA, Darmstadt, Germany.
All other trademarks are trademarks of their respective owners.
Copyright

2013 Millipore SAS, Guyancourt, France. Printed in France. All rights reserved. This
book or parts thereof may not be reproduced in any form without the written
permission of the publishers.
The photos are non-contractual.
Recycling
Directive 2002/96 EC: For European users only
The symbol “crossed bin” on a product or its packaging indicates that
the product should not be treated like household waste when discarded.
Instead the product should be disposed of at a location that handles
discarded electric or electronic equipment.
Proper disposal of equipment containing electric or electronic
components will help to reduce pollution effects to the environment or
to human health. Proper recycling of these products helps in
environmental preservation and helps to protect natural resources. For
more information about recycling of products containing electric or
electronic components, please contact your local recycling representative
or organization.

Milli-Q® Reference System 5
Safety Information
Statement
Your Milli-Q® System should be installed and operated according to the instructions in
this manual.
In particular, the hydraulic and electrical specifications should be followed and met.
It is important to use this equipment as specified in this manual; using this equipment
in a different manner may impair the safety precautions of the Milli-Q® System.
Symbols
This ATTENTION symbol is used to refer to instructions in this manual that need
to be done carefully.
These symbols are used to indicate that proper safety equipment has to be used.
Protective glasses and gloves must be worn.
This UV RADIATION sticker is used to refer to a position on the water system
Cabinet or inside of it where exposure to UV light is possible.
This DANGER sticker is used to refer to a position on the water system Cabinet
or inside of it that could be hazardous.
This ELECTRICAL GROUND sticker is used to refer to a position on the water
system Cabinet or inside where an electrical ground connection is made.
This ELECTRICAL DANGER sticker is used to refer to a position on the water
system Cabinet or inside where an electrical danger could exist.
Do not remove the covers of the Milli-Q® System at any time.
Electrical and mechanical components inside the Milli-Q® System could pose a hazard.
A qualified Millipore SAS Service Representative should perform any work that needs to
be done while the Milli-Q® System is opened.

Milli-Q® Reference System 7
Table of Contents
Product Information..........................................................................................................................................9
Overview .....................................................................................................................................................................................9
Cabinet..................................................................................................................................................................................... 10
Consumables .......................................................................................................................................................................... 15
Specifications and requirements ..................................................................................................................................... 17
Installation .......................................................................................................................................................20
Overview .................................................................................................................................................................................. 20
Alarms generated during installation............................................................................................................................. 21
POD Unit, tubing and power cord.................................................................................................................................... 22
Installing the Q-Gard® Pack.............................................................................................................................................. 25
Rinsing the System............................................................................................................................................................... 28
Installing a POD Pak............................................................................................................................................................. 30
Registering UV Lamp timer................................................................................................................................................ 32
Calibrating the Flowrate..................................................................................................................................................... 34
Software ...........................................................................................................................................................36
Overview .................................................................................................................................................................................. 36
Software Map ........................................................................................................................................................................ 37
Standby Mode........................................................................................................................................................................ 38
General information............................................................................................................................................................. 38
Description of Standby Menu ........................................................................................................................................... 39
Manager Menu ...................................................................................................................................................................... 41
Description.............................................................................................................................................................................. 41
Ready Mode............................................................................................................................................................................ 44
General information............................................................................................................................................................. 44
Description of Ready Menu ............................................................................................................................................... 45
Using the Milli-Q® System .............................................................................................................................48
Overview .................................................................................................................................................................................. 48
Dispensing water................................................................................................................................................................... 49
Viewing water quality ......................................................................................................................................................... 52
Viewing Operation................................................................................................................................................................ 53
Viewing Consumable Status.............................................................................................................................................. 55
Calling Millipore SAS........................................................................................................................................................... 56
Viewing Information............................................................................................................................................................ 57
Maintenance ....................................................................................................................................................59
Overview .................................................................................................................................................................................. 59
Maintenance Schedule........................................................................................................................................................ 60
Replacing the Q-Gard® Pack............................................................................................................................................. 61
Replacing the Quantum® Cartridge................................................................................................................................ 64
Replacing a POD Pak............................................................................................................................................................ 68
Cleaning the Inlet Strainer ................................................................................................................................................ 71
Calibrating the Flowrate..................................................................................................................................................... 74
Alarms ...............................................................................................................................................................75
Overview .................................................................................................................................................................................. 75
Alarm Information................................................................................................................................................................ 76
Summary of Alarm messages............................................................................................................................................ 80

8 Milli-Q® Reference System
Alerts.................................................................................................................................................................82
Overview...................................................................................................................................................................................82
Alert information...................................................................................................................................................................83
Summary of Alert messages...............................................................................................................................................88
Ordering Information ......................................................................................................................................90
Consumables, Accessories and Systems.........................................................................................................................90

Milli-Q® Reference System 9
Product Information
Overview
Purpose
This chapter contains topics related to the System.
Some of the more important topics in this chapter are:
•installation requirements,
•consumable information and
•
dimensions of various components of the System
Contents
This chapter contains the following topics:
Topic
See Page
Cabinet
10
Consumables
15
Specifications and requirements
17

10 Milli-Q® Reference System
Cabinet
Overview
Item
Description/Name
A
Point Of Delivery (POD)
B
POD Pak
C
POD Arm
D
Connections for tubings, power cord, level sensor and other cables
E
Q-GardPack
F
POD Mast
G
Main Display
H
QuantumCartridge
Main Display
function
The Main Display is used to navigate the System software.
Continued on next page
G
E
A
B
F
C
H
D

Milli-Q® Reference System 11
Cabinet, Continued
Details of the
Main Display
Item
Description
1
LED’s
2
Main LCD
3
Main Keypad
Right
The use of the Right Keypad button is shown below. It is used to move to the next
screen.
In this example, the system is changed from STANDBY Mode to READY Mode.
Diagram 1
Action
Diagram 2
Press .
Left
The use of the Left Keypad button is shown below. It is used to move to the former
screen.
Diagram 1
Action
Diagram 2
Press .
Continued on next page
1
3
2

12 Milli-Q® Reference System
Cabinet, Continued
Up
The use of the Up Keypad button is shown below. It is used to scroll up in a menu.
Diagram 1
Action
Diagram 2
Press .
Down
The use of the Down Keypad button is shown below. It is used to scroll down in a
menu.
Diagram 1
Action
Diagram 2
Press .
Validate
The use of the Validate Keypad button is shown below. It is used to confirm a
parameter modification.
Diagram 1
Action
Diagram 2
Press .
Continued on next page

Milli-Q® Reference System 13
Cabinet, Continued
READY Mode –
water quality
values
The READY Mode screen display is explained below.
Diagram
Explanation
In this example, the water dispensed from the POD
Unit has:
•a resistivity of 18.2 MΩ.cm,
•is temperature compensated (TC) at 25°C,
•a temperature of 24.9°C, and
•the TOC value is:
−not indicated with a Milli-Q® Reference System,
and
−indicated with a Milli-Q® Reference A+ System.
NOTE:
This Milli-Q® Reference System does not have a
built-in TOC indicator and therefore does not
display a TOC value. Should you wish to have a
display of the TOC value, please contact Millipore
SAS and inquire about availability of the TOC
Indicator Upgrade Kit.
In this example, there are no water quality
measurements to display. The water quality is only
displayed when it is actually measured during water
delivery or recirculation.
LEDs
The LEDs are described below.
Item
Description
Green LED
System is operating within specifications.
Yellow LED
An Alert is present.
Red LED
An Alarm is present.
NOTE:
If an Alarm and an Alert are present at the same time, then only the red LED is lit.
The red and yellow LEDs are never lit at the same time.
Continued on next page

14 Milli-Q® Reference System
Cabinet, Continued
Port and cables
The port and cable connections are explained below.
Item
Description
Item
Description
1
Feedwater port
4
Termination Plug connection
(maximum 5 VDC)
2
Ethernet connection
(maximum 5 VDC)
5
Accessories connection
(maximum 24 VDC)
3
Level Sensor
(maximum 5 VDC)
6
Power Entry connection
(100-240 VAC)
1
4
6
3
2
5

Milli-Q® Reference System 15
Consumables
Flow diagram
The water flow through a System is shown here in a flow diagram.
The various consumables are described below.
Item
Description
A
Q-Gard® Pack
B
UV 185 nm Lamp
C
Quantum® Cartridge
D
POD Pak
Q-Gard® Pack
The Q-Gard® Pack is used to remove ions and organic molecules from the feedwater.
Item
Description
Q-Gard® T1 Pack
The Q-Gard® T1 Pack is used when the feedwater comes
from RO, distillation or Electrodeionisation (EDI).
An example of RO or EDI feedwater is the water coming
from either a RiOs™ System or Elix®Water Purification
System.
This type of feedwater typically has some ions but
contains little organic, particulate and colloidal
contamination.
Q-Gard® T2 Pack
The Q-Gard® T2 Pack is used whenever the feedwater
comes from a source other than mentioned above and
has a Fouling Index ≤ 5.
Q-Gard® T3 Pack
The Q-Gard® T3 Pack is used whenever the feedwater
comes from a source other than mentioned above and
has a Fouling Index
>
5.
UV 185 nm
Lamp
T he dual wavelength UV 185 nm Lamp emits light at 185 nm and at 254 nm.
The UV 185 nm Lamp kills bacteria and reduces the level of organic molecules in the
water.
Continued on next page
A
B
C
D

16 Milli-Q® Reference System
Consumables, Continued
Quantum®
Cartridge
The Quantum® Cartridge removes trace levels of ions and organic molecules.
Item
Description
Quantum® TIX
Cartridge
The Quantum® TIX Cartridge contains only ion exchange
resin.
This type of Quantum® Cartridge is used when
maintaining absolutely trace levels of ions is critical.
Quantum® TEX
Cartridge
The Quantum® TEX Cartridge contains ion exchange resin
and synthetic carbon.
These purification media are used when the Milli-Q
Water needs to have both trace levels of ions and trace
levels of organic molecules.
POD Pak
The POD Pak is the final water purification device.
It is attached to the Point of Delivery outlet.
The POD Pak provides additional quality and insurance that trace contaminants related
to specific applications are removed just before ultrapure water is delivered.

Milli-Q® Reference System 17
Specifications and requirements
Milli-QWater
quality
The water delivered from a POD Unit has the following characteristics.
Parameter
Specification
Units
Resistivity
18.2
MΩ.cm @25°C
TOC
≤5
ppb
Particulates > 0.22 µm**
< 1
Particulates/mL
Bacteria**
< 0.1
cfu/mL
Pyrogens*
< 0.001
Eu/mL
RNases*
< 0.01
ng/mL
DNases*
< 4
pg/µL
Flow Rate**
0.05 – 2
L/min
(*) With BioPakFinal Filter
(**) With Millipakor BioPak® Final Filter
NOTE:
These specifications are valid for Elix® water feed within specification and for routine
operation. Some specifications may not be achieved at start-up.
Weight
The various weights are found in the table below.
Item
Operating
Weight
Dry Weight
Shipping
Weight
Milli-Q® Reference
System
19.5 kg
14.5 kg
19 kg
Electrical
The electrical specifications and data are found in the table below.
Parameter
Value
Voltage
100-230 VAC ±10%
Frequency
50-60 Hz ±10%
Main Fuse
3.15 Amp Fast Acting; 5 mm x 20 mm;
250 V safety voltage.
The fuse should be serviced by a qualified Millipore
SAS Service Representative.
Power Used
125 VA
Power Cord Length
2.5 metres
Electrical Ground
Earth Grounded
Power Cord use
The System is powered on and off by removing the
power cord from the wall outlet.
The power cord should be plugged into a wall outlet
that is accessible.
Continued on next page

18 Milli-Q® Reference System
Specifications and requirements, Continued
Dimensions
Materials of
construction
Please contact Millipore SAS for a list of the Materials of Construction.
Continued on next page
360 mm
416 mm
552 mm
783 mm
763
mm
422 mm
500
mm
458 mm

Milli-Q® Reference System 19
Specifications and requirements, Continued
Feedwater
The Feedwater requirements are listed here.
Parameter
Value
Type
Pre-treated water including one or several of the
following technologies:
•RO
•RO + EDI
•RO + DI
•Distillation, and
•
DI.
Conductivity
< 100 µS/cm @ 25°C
Pressure
0 bar < P < 0.3 bar
Temperature
5°C < T < 35°C
Maximum TOC
< 50 ppb
Fouling Index
< 5
pH
4 < pH < 10
Environmental
The Environmental requirements are listed here.
Parameter
Value
Altitude
< 3000 metres
Ambient operating temperature
4 – 40°C
Ambient storage temperature
4 – 40°C
Installation Category
II
Location
The System is intended for indoor
use only.
Pollution Degree
2
Relative humidity during storage
and operation
Maximum relative humidity 80% for
temperatures up to 31°C decreasing
linearly to 50% relative humidity at
40°C.
Noise Level
The noise level is < 50 dB at a distance of 1 metre.
Consumables
The minimum consumables required for installation are listed here.
Note that these items are not shipped with the System and must be ordered separately:
•Q-Gard® Pack,
•Quantum® Cartridge and
•POD Pak.

20 Milli-Q® Reference System
Installation
Overview
Purpose
This chapter explains how to install the System.
Contents
This chapter contains the following topics:
Topic
See Page
Alarms generated during installation
21
POD Unit, tubing and power cord
22
Installing the Q-Gard® Pack
25
Rinsing the System
28
Installing a POD Pak
30
Registering UV Lamp timer
32
Calibrating the Flowrate
34
Summary list
The steps shown below outline the sequence and major actions of a System installation.
Please refer to this list throughout the installation.
Step
Action
1
Put POD Arm onto POD Mast
2
Put Point Of Delivery onto POD Arm
3
Install feedwater tubing, termination plug and power cord
4
Power on the System, check date and time
5
Install, flush and rinse the Q-Gard® Pack and the Quantum®
Cartridge
6
Install and Register the POD Pak
7
Register the UV Lamp timer
8
Calibrate the Product Water flowrate