Radleys GreenHouse User manual

Instructions
Green ouse™
Blowdown Parallel
Evaporation System
Your Local Distributor
February 2023 | Issue 5
Radleys, Shire Hill, Saffron Walden, Essex, CB11 3AZ. United Kingdom.
Tel: [phone] Fax: [phone]
Email: [email protected]m Web: www.radleys.com

Page 1
Green ouse Blowdown Parallel Evaporation System
Index
Page 1 Index
Page 2 Introduction
Warranty
Page 3 Safety Information
Important WARNINGS
Page 4 Products & Accessories
Page 5 Products & Accessories
Page 6 Set-up & Operation
Page 7 Set-up & Operation - continued
Page 8 Set-up & Operation - continued
Page 9 Set-up & Operation - continued
Page 10 Temperature Control
Page 11 Example Evaporation Times
Examples of Blowdown Set-up Options
Page 12 Set-Up - Using Vial Racks or Micro Titer Plates
Page 13 Preventing Over-pressurisation
After Evaporation
Page 14 Choosing the Correct Gasket
Replacing the Gasket
WARRANTY - EMAIL BACK

Green ouse Blowdown Parallel Evaporation System
Thank you for purchasing your Green ouse Blowdown Evaporator System
Please read this instruction manual thoroughly before operating your unit.
Introduction
The Green ouse Blowdown Evaporator System brings all the benefits in productivity of multiple parallel evaporation
to the chemist at a fraction of the cost of other evaporators. The modular system uses a precisely controlled flow of inert
gas combined with digital heat control to carefully evaporate your samples.
• The Green ouse Blowdown Evaporator System allows you to either upgrade your existing Green ouse Parallel
Synthesiser to perform parallel evaporation, or to be used as a separate stand alone bench-top personal evaporator
• Chemists can perform up to 24 evaporations in parallel. Interchangeable plates (that fit the
Blowdown ead), with either 8 or 24 hollow pins, deliver an equal flow of gas to each tube, vial or well.
• Green ouse reaction tubes can be evaporated directly in the standard Green ouse reaction block without
the need to load or reload the block.
• A selection of vial racks are available to hold the most popular vial sizes in 6 x 4 and 4 x 2 arrays.
• Green ouse Blowdown Evaporator System is ideal for the evaporation of PLC fractions in vials or micro titer plates.
• Digitally controlled heating from a standard Carousel (or IKA) stirring hotplate gently adds energy to the sample
to speed the evaporation process. The stirring hotplates optional fuzzy logic digital temperature controller
will maintain the temperature with an accuracy of +/-0.5°C.
• This precise heat control and the absence of a vacuum will protect your sample and avoids bumping.
• The Flowmeter maintains an accurately metered flow rate of inert gas to optimise the evaporation rate without splashing.
• Nickel plated safety pressure relief valves on both the Green ouse Blowdown ead and nitrogen inlet ensure
protection against over pressurisation.
• Environmentally friendly enclosed design contains evaporating solvent. With a a unique glass condenser system,
cooled with dry ice/acetone, ensuring efficient condensation and minimal loss of solvent to the environment.
Warranty
The Green ouse Blowdown Evaporator System includes one-year full parts and labour warranty from date of
original purchase. Warranty will only be valid if a completed Warranty Email Back is returned
within 1 month of date of purchase (see last page).
In the event of product failure please contact your local distributor.
Please do not return any goods without prior agreement.
Page 2

Green ouse Blowdown Parallel Evaporation System
Safety Information
The following symbols are intended to assist the user in the safe and efficient
operation of the Green ouse Blowdown Evaporator System.
Important WARNINGS
Operate only in a fume cupboard with protective safety sash
Do not tamper with or obstruct Safety Relief Valves
This product is not suitable for pressurised reactions
DO NOT PRESSURISE C AMBER ABOVE 3psi
Blowdown ead Relief Valve vents at 4 to 6 psi
Gas Inlet Relief Valve vents at 4 to 6 psi
Do not use glass chamber if it is scratched, chipped or cracked
During blowdown ALWAYS ENSURE that inert gas flow rate is within recommended limits
Page 3
Warning
Applies when there is a possibility
of personal injury.
Important Note
Alerts the user to important facts.
!
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Important Note
Green ouse Blowdown Evaporation System should only be
operated by trained and competent personnel. As with all
experiments, care should be taken to monitor your evaporation at
all stages. The Green ouse Blowdown Evaporation System
should not be left unattended unless in a supervised area.
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Green ouse Blowdown Parallel Evaporation Systems
Products & Accessories
Page 4
Cat No Description Pk Qty
Green ouse Blowdown & Accessories
RR99670 Green ouse Blowdown ead 1
RR99672 Blowdown Long Pin Plate 6 x 4 (for Green ouse Tubes) 1
RR99673 Blowdown Pin Plate 6 x 4 1
RR99674 Blowdown Pin Plate 4 x 2 1
RR99677 Green ouse Blowdown Base Adaptor 1
RR99679 Blowdown Stand Alone Base 1
RR99680 Flowmeter 2 to 27 litres/min with Stand 1
RR99681 Gas Connection Tubing - 5m length 1
RR99684 Blowdown Condenser 1
RR99688 Blowdown 150ml Reservoir 1
RR99691 AT01 Vial Rack 4 x 2 (For 27.8mm OD Vials) 1
RR99692 AT02 Vial Rack 6 x 4 (For 13mm OD Vials) 1
RR99693 AT03 Vial Rack 6 x 4 (For 13.8mm OD Vials) 1
RR99695 AT05 Vial Rack 4 x 2 (For 24.3mm OD Vials) 1
RR99696 AT06 Vial Rack 6 x 4 (For 15mm OD Vials) 1
Green ouse Blowdown Parallel Evaporator:- Include all the important components
and accessories required for efficient operation
RR99657 System 16 - Green ouse Blowdown Basic Upgrade
Comprising of the following
RR99670 Green ouse Blowdown ead
RR99672 Long Blowdown Pin Plate 6 x 4 (for Green ouse Tubes)
RR99677 Green ouse Blowdown Base Adapter
RR99684 Blowdown Condenser
RR99688 Blowdown 150ml Reservoir
RR99658 System 17 - Green ouse Blowdown Complete Upgrade
Comprising of the following
RR99670 Green ouse Blowdown ead
RR99672 Long Blowdown Pin Plate 6 x 4 (for Green ouse Tubes)
RR99673 Blowdown Pin Plate 6 x 4
RR99674 Blowdown Pin Plate 4 x 2
RR99677 Green ouse Blowdown Base Adapter
RR99680 Flowmeter 2 to 27 litres/min with Stand
RR99681 Gas Connection Tubing - 5m length
RR99684 Blowdown Condenser
RR99688 Blowdown 150ml Reservoir
RR99691 AT01 Vial Rack 4 x 2 (For 27.8mm OD Vials)
RR99692 AT02 Vial Rack 6 x 4 (For 13mm OD Vials)
RR99693 AT03 Vial Rack 6 x 4 (For 13.8mm OD Vials)
RR99695 AT05 Vial Rack 4 x 2 (For 24.3mm OD Vials)
RR99696 AT06 Vial Rack 6 x 4 (For 15mm OD Vials)
RR99659 System 18 - Green ouse Blowdown Basic Stand Alone
Comprising of the following
RR99670 Green ouse Blowdown ead
RR99672 Long Blowdown Pin Plate 6 x 4 (for Green ouse Tubes)
RR99673 Blowdown Pin Plate 6 x 4
RR99692 AT02 Vial Rack 6 x 4 (For 13mm OD Vials)
RR99679 Blowdown Stand Alone Base
RR99604 Green ouse Glass Cylinder
RR99684 Blowdown Condenser
RR99688 Blowdown 150ml Reservoir
Green ouse Blowdown Parallel Evaporator:- Include all the important components
and accessories required for efficient operation
RR99660 System 19 - Green ouse Blowdown Basic Stand Alone + Stirrer
Comprising of the following

Green ouse Blowdown Parallel Evaporation Systems
Products & Accessories - Continued
Page 5
RR99670 Green ouse Blowdown ead
RR99672 Long Blowdown Pin Plate 6 x 4 (for Green ouse Tubes)
RR99673 Blowdown Pin Plate 6 x 4
RR99692 AT02 Vial Rack 6 x 4 (For 13mm OD Vials)
RR99679 Blowdown Stand Alone Base
RR99604 Green ouse Glass Cylinder
RR99684 Blowdown Condenser
RR99688 Blowdown 150ml Reservoir
RR98072 Carousel Stirring otplate 230 volt UK Plug
RR98073 Carousel Temperature Controller
RR99661 System 20 - Green ouse Blowdown Complete Stand Alone
Comprising of the following
RR99670 Green ouse Blowdown ead
RR99672 Long Blowdown Pin Plate 6 x 4 (for Green ouse Tubes)
RR99673 Blowdown Pin Plate 6 x 4
RR99674 Blowdown Pin Plate 4 x 2
RR99677 Green ouse Blowdown Base Adapter
RR99679 Blowdown Stand Alone Base
RR99680 Flowmeter 2 to 27 litres/min with Stand
RR99681 Gas Connection Tubing - 5m length
RR99604 Green ouse Glass Cylinder
RR99684 Blowdown Condenser
RR99688 Blowdown 150ml Reservoir
RR99691 AT01 Vial Rack 4 x 2 (For 27.8mm OD Vials)
RR99692 AT02 Vial Rack 6 x 4 (For 13mm OD Vials)
RR99693 AT03 Vial Rack 6 x 4 (For 13.8mm OD Vials)
RR99695 AT05 Vial Rack 4 x 2 (For 24.3mm OD Vials)
RR99696 AT06 Vial Rack 6 x 4 (For 15mm OD Vials)
RR99662 System 21 - Green ouse Blowdown Complete Stand Alone + Stirrer
Comprising of the following
RR99670 Green ouse Blowdown ead
RR99672 Long Blowdown Pin Plate 6 x 4 (for Green ouse Tubes)
RR99673 Blowdown Pin Plate 6 x 4
RR99674 Blowdown Pin Plate 4 x 2
RR99677 Green ouse Blowdown Base Adapter
RR99679 Blowdown Stand Alone Base
RR99680 Flowmeter 2 to 27 litres/min with Stand
RR99681 Gas Connection Tubing - 5m length
RR99604 Green ouse Glass Cylinder
RR99684 Blowdown Condenser
RR99688 Blowdown 150ml Reservoir
RR99691 AT01 Vial Rack 4 x 2 (For 27.8mm OD Vials)
RR99692 AT02 Vial Rack 6 x 4 (For 13mm OD Vials)
RR99693 AT03 Vial Rack 6 x 4 (For 13.8mm OD Vials)
RR99695 AT05 Vial Rack 4 x 2 (For 24.3mm OD Vials)
RR99696 AT06 Vial Rack 6 x 4 (For 15mm OD Vials)
RR98072 Carousel Stirring otplate 230 volt UK Plug
RR98073 Carousel Temperature Controller

Green ouse Blowdown Parallel Evaporation System
Green ouse Blowdown ead Applications
The Green ouse Blowdown ead can be used in two basic modes:
1. The RR99670 Blowdown ead can be used to upgrade your existing
Green ouse Parallel Synthesiser and reaction block for blowdown
evaporation. Evaporation can either be undertaken with the Green ouse
reaction block and tubes in place; or by inserting the optional RR99677
Green ouse Base Adaptor, you can adapt the standard Green ouse base to
accept either a standard micro titer plate or any one of the five vial racks.
2. Use the Green ouse Blowdown ead as part of a stand alone unit using the
RR99679 Blowdown Stand Alone Base. This lower profile base will accept
either a standard micro titer plate or any one of the five vial racks.
Safety Pressure Relief Valves
The Green ouse Blowdown head features two Safety Pressure Relief Valves.
a. Gas Inlet Safety Pressure Relief Valve - designed to prevent excessive
pressure damaging the flow distribution plate within the blowdown head.
b. Blowdown ead Safety Pressure Relief Valve - designed to prevent
pressure from building up within the chamber.
Both valves are plated internally and externally with electroless nickel plating
giving them superior chemical resistance to most solvents and acids, when
compared with unplated aluminium or stainless steel. They also contain astelloy
springs and use
a Kalrez (fluoropolymer) sealing O-ring. (Gas Inlet Safety Relief Valve uses a
Viton O-ring). Valves are individually tested and certified to crack at 4 to 6psi +/-
5%.
Set-Up & Operation
Warning
This product is not suitable for pressurised reactions
DO NOT PRESSURISE C AMBER ABOVE 3psi
Blowdown ead Relief Valve vents at 4 to 6 psi.
Gas Inlet Relief Valve vents at 4 to 6 psi.
Do not use glass chamber if it is scratched, chipped or cracked
during blowdown
!
Page 6
Important Note
Safety Procedures for Safety Pressure Relief Valves
1. On every occasion, prior to use of your Green ouse ensure that
both Safety Pressure Relief Valves are not stuck to their seating.
This is achieved by gently pulling up the cap until the valve
comes off its seating.
2. Use only a regulated inert gas supply (nitrogen recommended)
not exceeding 0.5 bar (7psi).
3. The nitrogen supply must be at sufficient pressure to obtain
a flow rate within the recommended limits.
4. Do not attempt to dismantle or modify the Safety Pressure Relief
Valves. These are not user serviceable items and must only be
replaced with approved replacements.
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1.
2.
a.
b.

Green ouse Blowdown Parallel Evaporation System
Using Blowdown ead with an Existing Green ouse Synthesiser
Existing Green ouse users need only purchase the RR99657 System 11 -
Green ouse Blowdown Basic Upgrade kit. This allows users to do blowdown
evaporation in a standard Green ouse reaction block with reaction tubes.
Should users wish to use the Green ouse Blowdown Evaporator for other vials or
micro titer plates, users need to purchase the RR99658 System 12 - Green ouse
Blowdown Complete Upgrade kit.
Set-Up & Operation - continued
Fitting the Blowdown Pin Plate to the Blowdown ead
Select the appropriate
Blowdown Pin Plate.
Fix the Blowdown Pin
Plate to the Blowdown
ead by locating it
over the two pins on
the underside of the
head and securing
it with the securing
screws (orange handles).
Warning
The Green ouse Blowdown ead should only be operated
in a fume cupboard.
!
Important Note
Take care not to over tighten these fixing screws as this can
damage the threads.
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Allow the Reaction Block to cool to ambient temperature before
attempting to transfer or evaporate the solvent.
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Place Green ouse Reaction Block with reaction tubes containing solvent to be
evaporated into the Green ouse base, taking note of the appropriate rack
position (A1-D6) for each sample.
Alternatively if a reaction has just been performed in the Green ouse, simply
remove the Reflux or Additions ead and replace with the Green ouse
Blowdown ead.
Ensure that the circular gasket is properly located in its groove, then carefully
place glass chamber on to silicone (or optional Viton) gasket.
1
2
RR99673
6 x 4 Blowdown
Pin Plate for 24
position Vial
Racks
or MTPs
RR99672
6 x 4 Blowdown
Long Pin Plate
for Green ouse
Reaction Block and
Reaction Tubes
RR99674
4 x 2 Blowdown
Pin Plate for 8
position Vial Racks
or MTPs
Page 7

Set-Up & Operation - continued
Connect Flowmeter to suitable regulated inert gas supply (nitrogen recommend-
ed) not exceeding 0.5 bar (7psi). Then connect gas outlet tube of Flowmeter to
inlet of Green ouse Blowdown ead. Using gas connection tubing RR99681 or
other appropriate tubing.
Green ouse Blowdown Parallel Evaporation System
Locate Green ouse base on to stirring hotplate (maximum top plate diameter
135mm).
The circular recess in the base fits snugly around the top plate, yet allows it to be
lifted on or off the stirring hotplate with ease.
Connect the RR98073 Fuzzy Logic Digital Temperature
Controller connection (DIN 12 878 Class 2) to the
connection port at the rear of the stirring hotplate.
Insert the probe through the central Suba-Seal, so that
the tip is located into the reaction block.
Using the locating pins slide the Blowdown ead down into position on the glass
chamber. Use the two metal sealing knobs to seal the Blowdown ead and
ensure a gas tight chamber. The sealing knobs need only to be hand tight.
5
6
Important Note
Over tightening may damage the thread. Do not use a spanner
or wrench to tighten sealing knobs.
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Take care when locating the lid to be sure that the pins and tubes,
vials or wells line up correctly. A useful tip is to align the two guide
supports first by feeling with your fingers.
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Important Note
Prior to use of your Green ouse Blowdown
Evaporator ensure that neither of the Safety
Pressure Relief Valves are stuck to their seat-
ing. This is achieved by gently pulling up the
cap until the valve comes off its seating.
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Warning
Do not use glass chamber if it is scratched, chipped or cracked,
as even the smallest flaw could lead to failure.
!
4
Page 8
Warning
All gas fittings must be secured properly so they cannot blow off
under operation. Before using the Flowmeter refer to the separate
Flowmeter Instructions.
!

Connect gas outlet from Green ouse Blowdown Evaporator to the inlet at the top
of the condenser. Ensure condenser is properly secured and clamped. Screw the
solvent collection flask to the bottom of the condenser.
Fill reservoir of condenser with dry ice and cautiously add acetone in small
portions until most of the dry ice is covered.
Set-Up & Operation - continued
Green ouse Blowdown Parallel Evaporation System
Page 9
If the reaction tubes are less than half full, slowly and carefully open the
Flowmeter valve until the flow rate is 10 to 15 litres per minute.
If the flow rate is correct, it should just ‘dimple’ the solvent surface.
7
8
Important Note
Ensure that the cooling reservoir is kept topped up with dry ice
during extended evaporations!
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Switch on the heating control on the stirring hotplate and set the Fuzzy Logic
Temperature controller to an appropriate value. Normally 40˚C is enough
and this should not normally cause decomposition of product. owever
this temperature may be increased for high boiling solvents such as DMF
or reduced for thermally less stable compounds.
See page 13 for important information on pressure control.
Important Note
If the tubes are more than half full use a slower flow rate
- increasing the flow rate as the solvent evaporates.
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Excessive flow rates may cause solvent to be ejected from the tubes
with loss of material and possible cross-contamination. Do not
immerse the blowdown pins below the surface of the solvent.
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9
Warning
Dry ice causes burns! Ensure that suitable protective clothing
(eye protection, insulated gloves and apron) is used during filling
or emptying.
!
Warning
The Blowdown ead Safety Pressure Relief Valve and Gas Inlet Safety Pressure Relief Valve are designed to
vent at nominally 4 to 6psi. Therefore under normal and correct operation procedures neither valve should be
venting.
!
Important Note
Do not use air for evaporation in the Green ouse Blowdown due to
the possibility of oxidation of the product during evaporation.
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Warning
When heating reactions take care not to touch the base or head as
these may have become hot during evaporation.
!
Warning
We recommend a maximum operating temperature of no more than
150˚C. In normal use the Green ouse Blowdown Evaporator will not
be used at temperatures much above 40˚C.
!
Green ouse Blowdown Parallel Evaporation System
Page 10
Temperature Control
For accurate temperature control during evaporation we recommend using the
RR98073 Fuzzy Logic Digital Temperature Controller.
To connect the RR98073 Fuzzy Logic Digital Temperature Controller, plug the
connector (DIN 12 878 Class 2) into the port at the rear of the stirring hotplate.
Important Note
Always ensure that the temperature sensor is completely inserted
into the block or rack.
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Set the temperature to the desired level by following the
instructions of RR98073 Fuzzy Logic Digital Temperature
Controller. The set temperature can be maintained to +/- 0.5˚C.
The maximum recommended operating temperature is 150˚C.
owever in normal use the Green ouse Blowdown Evaporator
will not be used at temperatures much above 40˚C.
The stainless steel temperature sensor of the RR98073 is
positioned in the centre of the Green ouse Blowdown ead
(through the Suba-Seal) to monitor and control the temperature
of the reaction block or rack.
Warning
Read the RR98072 Carousel Stirring otplate and RR98073 Fuzzy
Logic Digital Temperature Controller instructions thoroughly before
operation.
!
Important Note
Green ouse Blowdown Evaporation System should only be
operated by trained and competent personnel. As with all
experiments, care should be taken to monitor your evaporation at
all stages. The Green ouse Blowdown Evaporation System should
not be left unattended unless in a supervised area.
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Green ouse Blowdown Parallel Evaporation System
Number of Volume Vial Evaporation
Solvent Samples (ml) Type Time (min)
Methanol 24 2 3.5ml Vial 20
Methanol 8 5 20ml Vial 22
Acetonitrile 24 2 3.5ml Vial 20
Acetonitrile 24 2 Green ouse Tube 35
Water 8 5 20ml Vial 157
DMF 24 2 3.5ml Vial 138
DMF 8 5 20ml Vial 145
40˚C Base Temperature. Flowrate 10 l/min (8 well), 20 l/min (24 well)
Example Evaporation Times
Green ouse with
Blowdown ead,
Standard
Green ouse
Base and
Green ouse
Reaction Block
Green ouse with
Blowdown ead,
Standard
Green ouse
Base, Base
Adapter and 24
Position Vial
Rack
Green ouse with
Blowdown ead,
Standard
Green ouse
Base, Base
Adapter and 8
Position Vial
Rack
Green ouse with
Blowdown ead,
Standard
Green ouse
Base, Base
Adapter and 24
Position MTP
Green ouse with
Blowdown ead,
low profile Stand
Alone Base and
24 Position Vial
Rack
Green ouse with
Blowdown ead,
low profile Stand
Alone Base and
8 Position Vial
Rack
Green ouse with
Blowdown ead,
low profile Stand
Alone Base and
24 Position MTP
Examples
of Blowdown
Set-up
Options
Page 11

Green ouse Blowdown Parallel Evaporation System
Set-Up - Using Vial Racks or Micro Titer Plates
Using the Green ouse Blowdown Evaporator as a Stand Alone Unit
As a stand alone unit, the Green ouse Blowdown Evaporator is used only for
Blowdown and not for synthesis. The Stand Alone Base is used instead of the
standard Green ouse Base (the Blowdown Base Adaptor is not required).
As a Stand Alone unit the Green ouse Blowdown Evaporator is used to
evaporate solvents from vials or micro titer plates only.
Vial racks are shown above and listed under Accessories on page 4. These racks
simply locate in the Blowdown Stand Alone Base and require no special fitting.
When using vials rack always select the correct Blowdown Pin Plate.
RR99673 - Blowdown Pin Plate for 24 position racks or MTPs.
RR99674 - Blowdown Pin Plate for 8 position racks or MTPs.
Important Note
The Stand Alone Unit is not designed for the Blowdown evaporation
of Green ouse reaction tubes. This can only be undertaken using
the standard Green ouse Base and Green ouse reaction block.
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AT01
AT05 AT06
AT03
AT02
Base Adapter with
8 position vial rack
Base Adapter with
24 position vial rack
Base Adapter with
24 position MTP
Stand Alone Base with
8 position vial rack
Stand Alone Base with
24 position vial rack
Stand Alone Base with
24 position MTP
Page 12
Using the Standard Green ouse Base with the Blowdown Base Adaptor
The Blowdown Base Adaptor allows use of vial racks or standard micro titer
plates. Choose from 5 standard vial racks in 24 or 8 position formats.
Vial racks are shown right and listed under Accessories on page 4. These racks
simply locate in the Blowdown Base Adaptor and require no special fitting.
When using vials rack always select the correct Blowdown Pin Plate.
RR99673 - Blowdown Pin Plate for 24 position racks or MTPs.
RR99674 - Blowdown Pin Plate for 8 position racks or MTPs.
aving fitted the Blowdown Pin Plate (see page 7), Blowdown
Base Adaptor and appropriate vial rack or micro titer plate now
return to page 8 and follow instructions.
aving fitted the Blowdown Pin Plate (see page 7) and appropriate vial rack
or micro titer plate now return to page 8 and follow instructions.

Green ouse Blowdown Parallel Evaporation System
Preventing Over-pressurisation
After Evaporation
Should over-pressure venting occur:
1. Immediately turn off gas supply
2. Either disconnect gas inlet or lift Blowdown ead Safety Pressure Relief Valve
to remove excess pressure.
3. Immediately turn off any heating.
Important Note
Allow dry ice/acetone mixture to reach ambient temperature before
disposing of it into a suitable waste solvent container.
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Warning
The Blowdown ead Safety Pressure Relief Valve and Gas Inlet
Safety Pressure Relief Valve are designed to vent at nominally
4 to 6psi. Therefore under normal and correct operation
procedures neither valve should be venting.
!
When evaporation is complete:
a. Turn off heat and allow gas to flow until the base unit is cool
b. Turn off inert gas supply
c. Disconnect gas inlet and outlets to Blowdown ead
d. Remove the two sealing knobs and remove the Blowdown ead
e. Carefully remove the circular glass and lift out the rack
f. Remove flask from bottom of cold trap and allow solvent to warm to ambient
temperature
Warning
Dry ice causes burns! Ensure that suitable protective clothing
(eye protection, insulated gloves and apron) is used during filling
or emptying.
!
Page 13

The Green ouse Blowdown Evaporator are supplied as standard with Silicone
Rubber Gaskets (RR99606) in the Base Unit and the Reflux and Additions eads
(if supplied). These gaskets are suitable for the majority of applications but in
some cases the optional Viton Rubber Gaskets (RR99605) will be more suitable.
When to use the Silicone Rubber Gaskets
The Silicone Rubber Gaskets will be suitable for most applications and show
good resistance to most common organic solvents and reagents including
acetone, acetonitrile, alcohols, acetic acid, esters, DMF, DMSO and mineral
acids and bases etc. It should be borne in mind that resistance testing is
normally done with the material totally immersed in the solvent, whereas with
the Green ouse Blowdown Evaporator in normal operation the gaskets should
only be exposed to low concentrations of vapours from solvents and reagents.
Silicone Rubber shows poor resistance to trifluoroacetic acid (TFA) and therefore
Viton may be preferred for applications involving this solvent.
When to use the Viton Rubber Gaskets
Viton shows superior resistance to chlorinated hydrocarbons such as
dichloromethane and chlorobenzene compared with Silicone Rubber. It is also
more resistant to aromatic hydrocarbons. Viton exhibits relatively good resistance
to trifluoroacetic acid (TFA) and is the preferred gasket in this case.
Thermal Resistance of Gaskets
Both the Silicone Rubber and Viton Gaskets have service temperatures well
in excess of the normal maximum recommended operating temperature of the
Green ouse (ca 150˚C).
In normal use the Green ouse Blowdown Evaporator will not be used at
temperatures much above 40˚C.
Green ouse Blowdown Parallel Evaporation System
Choosing the Correct Gasket
Replacing the Gasket
ow long should the gasket last ?
The gaskets are a consumable item and they will need replacing. ow long
they last depends very much on what you expose them to. Repeatedly splashing
solvents and reagents directly on to the gaskets will greatly reduce their life.
RR99605 - Viton Rubber Gaskets, pack of 2
RR99606 - Silicone Rubber Gaskets, pack of 2
Changing the Gaskets
The Gaskets should be inspected regularly and replaced when they show signs of
deterioration or embrittlement. They can easily be removed with a pin or
something similar, taking care not to damage the groove in which they seat. The
new gaskets are then simply pushed into place ensuring that they are properly
located in the machined grooves. You will not require glue or sealant to hold the
gaskets in place.
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