3D Histech PANNORAMIC DESK DW II 3.0.4 User manual

PANNORAMIC® DESK DW II 3.0.4
USER’S GUIDE
December 8, 2021 –Rev.1

PANNORAMIC® DESK DW II 3.0.4
CONTENTS
MARCH 30, 2021
1
Contents
Contents 1
Disclaimer 3
Declaration of Conformity 5
About this User's Guide 6
Character Formats and Symbols 7
Notes Regarding Operational Safety 8
Notes on Warranty 12
Terms and Abbreviations 13
1Product Description 14
1.1 Product overview 14
1.1.1 Intended use 14
1.1.2 Features and benefits 14
1.1.3 Warning and information labels 15
1.1.4 Base unit 16
1.2 System overview 16
1.2.1 Pannoramic® DESK DW II system 16
1.2.2 Hardware options 18
1.2.3 Control software 19
2Installation 20
2.1 Operation system of the control computer 21
2.2 Control computer ports 22
2.3 Connectors and Cables 23
2.4 External power supply unit 24
2.5 Power the scanner on/off 24
3Preparing Slides 25
3.1 Affixing barcode stickers to slides 26
3.2 Inserting and removing slides 27
4Software Description 33
4.1 Starting / exiting Pannoramic® Scanner 3.0.4 software application 33
4.1.1 Starting the software 33
4.1.2 Exiting the software 34
4.2 Main window functions 34
5Scanning Modes and Settings 51

PANNORAMIC® DESK DW II 3.0.4
CONTENTS
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5.1 Brightfield scanning mode 51
5.1.1 Profile settings panel 52
5.1.2 Microscope control panel 59
5.1.3 Quick preview functions 71
5.1.4Quick microscope functions 72
5.1.5 Bottom menu bar of the main window 73
5.2 Planner mode 74
5.2.1 General functions at the main menu 75
5.2.2 Slide view with card 76
5.2.3 Table view mode 78
5.2.4 Card collection view mode 79
5.3 Profile and preview overview on the planner 80
5.4 Progress features 81
6Settings and Service 82
6.1 Settings 82
6.2 Service 91
6.3 Hosting 96
7Using Profiles 98
8Troubleshooting and Maintenance 99
8.1 Recovery functions 99
8.2 Safety information 99
8.2.1 Cleaning the device 100
8.2.2 Preventive maintenance 100
8.3 Troubleshooting 101
8.4 Maintenance 103
8.4.1 Removing the protective cover 103
8.4.2 Removing a slide 104
8.4.3 Transporting Pannoramic DESK DW II 106
9Technical Data 107

PANNORAMIC® DESK DW II 3.0.4
DISCLAIMER
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Disclaimer
Copyright © 2001-2021 3DHISTECH Ltd.
All rights reserved.
Intellectual property related to the 3DHISTECH products are as follows:
•P1300124; PCT/HU2014/000020; EP 14745228.8.; US 14/771.380
•P0700404; PCT/HU2008/000065; EP 08762668.5.; US 12/663.537
•P1700279; PCT/HU2018/050030
•P1700483
•P1500394; PCT/HU2016/050039; EP 16840280.8.; US 15/756.370
•P0700409; US 2008/0306964
•P0800181; PCT/HU2009/000027; EP 09721248.4.
•P0600435; PCT/HU2007/000047; EP 2024772; US 12/301.781
•P0600177; PCT/HU2007/000018; EP 1.994.398; US 12/281.566
•P0900741; PCT/HU2010/000130; EP 10812989.1.
•P0900142; PCT/HU2010/000027; EP 10726183.6
•P101036; PCT/IB2005/050351; EP 1789831; US 7.663.078
•P0301911; PCT/HU04/00019; EP 1644767; US 7327515
The above mentioned granted patents, granted utility model, registered trademarks, pending
international and national patent applications and the other corresponding IP are the sole
properties of the 3DHISTECH Ltd.
3DHISTECH Ltd. is not liable for damage of whatever nature (including, but not limited to,
general or specific damage, indirect damage, consequential damage or incidental damage,
including the results of the analysis of the digitized slides, for example, change of health status
related to erroneous diagnosis from the digitized slide(s)) that stems from or is associated with
use of Product, digitized slides, quality of staining, quality of stained slides, quality of used
method of staining. 3DHISTECH Ltd. assumes no responsibility for the functionality and fault-
free condition of your “application programs” (Workflows, VBA macros, Commander scripts).

PANNORAMIC® DESK DW II 3.0.4
DISCLAIMER
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CAUTION
This product has not been approved or cleared as a medical device by the U.S. Food and Drug
Administration.
Do not use this device in close proximity to sources of strong electromagnetic radiation (e.g.
unshielded intentional RF sources), as these may interfere with the proper operation.
Third-party disclaimer
3DHISTECH Ltd. is not liable for damage of whatever nature (including, but not limited to, general
or specific damage, indirect damage, consequential damage or incidental damage, including
damage resulting from lost profits, interruption of business, loss of business information,
pecuniary loss or similar damage) that stems from or is associated with the incorporated part of
this Product that is made by a third-party company.
THE SOFTWARE IS PROVIDED “AS IS” AND WITHOUT WARRANTY OF ANY KIND, EXPRESSED,
IMPLIED OR OTHERWISE, INCLUDING WITHOUT LIMITATION, ANY WARRANTY OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE.
Further Information
For the latest information on 3DHISTECH products and services, please visit our website at the
following URL: http://www.3dhistech.com.
Company Address
3 Öv Street, 1141 Budapest –HUNGARY

PANNORAMIC® DESK DW II 3.0.4
DECLARATION OF CONFORMITY
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Declaration of Conformity
3DHISTECH Ltd. declares that the product Pannoramic® DESK DW II slide scanner is designed and
produced with consideration of specified requirements according to standards listed below:
IEC 61010-1:2010, “Safety Requirements for Electrical Equipment for Measurement, Control, and
Laboratory Use –Part 1: General Requirements”
IEC 61010-2-101:2015, “Safety Requirements for Electrical Equipment for Measurement, Control,
and Laboratory Use –Part 2-101: Particular requirements for in vitro diagnostic (IVD) medical
equipment”
IEC 61010-2-081:2015, “Safety requirements for electrical equipment for measurement, control and
laboratory use –Part 2-081: Particular requirements for automatic and semi-automatic laboratory
equipment for analysis and other purposes”
IEC 62471:2006, “Photobiological safety of lamps and lamp systems”
Conformity with Directive IEC 61010-2-101 is marked by on the product labeling.
There is no further operator (user) action required in case of residual risks.
Further information may be obtained from the manufacturer:
3DHISTECH Ltd.
3 Öv Street
1141 Budapest –HUNGARY

PANNORAMIC® DESK DW II 3.0.4
ABOUT THIS USER'S GUIDE
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About this User's Guide
The purpose of this manual is to assist the user in the safe and reliable operation of the product
described. Before operating the device, you must carefully read this instruction manual, and
adhere to all WARNING and CAUTION notices (refer to chapter Notes Regarding Operational
Safety for more information), and a copy should be kept in the close to the scanner for reference
whenever required.
This User's Guide is a part of the Pannoramic® DESK DW II system identified by the following
article numbers:
• DE2BGHM00010100001
• DE2BGHM00010110001
• DE2BGHM00020100001
• DE2BGHM00020110001
• DEF1BGHM00010100001

PANNORAMIC® DESK DW II 3.0.4
CHARACTER FORMATS AND SYMBOLS
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Character Formats and Symbols
Example (text in bold)
Words or characters that appear on the screen. These include field names, screen and window
titles, push-button and menu names, paths, or options. Keys or hotkeys of the keyboard. For
example, function keys (e.g. F11, or Enter) or the Ctrl+M key combination.
Example (text in bold and italics)
Cross-references within this document or to other documents.
Warning!
Can cause irreversible damage or harm to the user of the product or the product itself if this
instruction is not followed.
Caution!
Can cause the product to not work properly if this instruction is not followed and alerts to a
potentially critical situation.
Notice:
Calls attention to some important information or feature.
Special attention should be paid to all information provided and the procedures described in
chapter Safety Information.

PANNORAMIC® DESK DW II 3.0.4
NOTES REGARDING OPERATIONAL SAFETY
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Notes Regarding Operational Safety
The below section of this User’s Guide contains information and warnings of a kind that must be
followed by owner/operator personnel.
Warning and advisory symbols which are used on the base unit of the Pannoramic® DESK DW II
and in the chapter Warning and information labels have the following meanings:
Caution!
Disconnect mains plug before any kind of intervention into the device!
Caution!
Crush hazard!
The Pannoramic® DESK DW II, including any of its original accessory components, should not be
operated in any other way than described in chapter Intended use.
Any of the following notes should be strictly observed:
Warning!
If operating the device other than specified by the manufacturer, the level of safety will
decrease.
Caution!
In the event of any non-conforming type of use, including non-conforming use of assemblies
or single parts, no liability will be assumed by the Manufacturer. This shall also apply to
service or repair work of any kind, which is performed by other than authorized service
personnel. All claims for warranty and warranty services will be null and void in any such
case.

PANNORAMIC® DESK DW II 3.0.4
NOTES REGARDING OPERATIONAL SAFETY
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Notice:
The safety level of the equipment after servicing will be identical with level of the original
equipment.
Warning!
Insert the power cord plugs only into a grounding outlet. The protective action must not be
rendered ineffective by extension cables without protective conductor. The Pannoramic®
DESK DW II has a built-in protection which must not be rendered ineffective by extension
cables without protective (earth-ground) conductor.
Warning!
The operation of the instrument in explosion-risk environments is not allowed.
Warning!
If protective devices are found to be ineffective, the Pannoramic® DESK DW II must be shut
down and precautions must be taken to prevent unintended usage. For necessary repair
work or work to restore proper operating condition, you should contact the 3DHISTECH
Customer Service.
Notice:
Electric power to the Pannoramic® DESK DW II is supplied via an internal mains power
supply unit. It allows for operation at line voltages in the range of 100 V to 240 V ±10%, 50-60
Hz, without any extra facilities required for voltage transformation.

PANNORAMIC® DESK DW II 3.0.4
NOTES REGARDING OPERATIONAL SAFETY
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Warning!
Check that your local line voltage is compatible with Pannoramic® DESK DW II specifications
before you turn power on.
Disconnect plug!
Remember to unplug the power cord before you open the Pannoramic® DESK DW II main
unit for maintenance.
Warning!
Only connect external devices to the instrument which are approved to avoid the risk of
electrical shock.
Warning!
The Pannoramic® DESK DW II does not include any special facilities to protect from samples
with an etching, potentially infectious, toxic, radioactive, or other health-damaging effect.
You are under obligation to comply with all currently binding legislation, notably, national
accident prevention rules when handling samples of this kind.
Caution!
Dirt or dust may adversely impact the operating capability of the Pannoramic® DESK DW II.
For this reason, measures must be taken to eliminate such influences on a maximum
possible degree. During periods of non-use, the Pannoramic® DESK DW II must be protected
with a dust cover. Check that power is turned off before you put the cover on.

PANNORAMIC® DESK DW II 3.0.4
NOTES REGARDING OPERATIONAL SAFETY
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Caution!
Do not position the equipment so that it is difficult to operate and to disconnect the device
if necessary.
Crush hazard!
There is crush hazard in the movement area of the slide insert during operation. Please note
that the digitizing process has to be interrupted and the insert moved via software to the
output position before removing the insert.
Warning!
The front door is equipped with an interlock switch. If the door is opened while a digitization
process is running, the process will be stopped instantly.
Warning!
A defective Pannoramic® DESK DW II is not classified as domestic waste. It must be properly
disposed in accordance with currently valid legal requirements.
Warning!
The Pannoramic® DESK DW II may not be operated by other than properly instructed
persons. Operating personnel must be fully aware of the potential dangers which a
particular field of application involves. The Pannoramic® DESK DW II is a precision
instrument which may suffer a significant reduction in operational functions or even physical
destruction following intervention performed in any nonconforming manner.

PANNORAMIC® DESK DW II 3.0.4
NOTES ON WARRANTY
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Notes on Warranty
3DHISTECH Ltd. –as the Product Manufacturer –warrants the Pannoramic® DESK DW II to be
free from faults in material and workmanship at the moment of installation. Defects must be
notified immediately on identification and maximum efforts must be undertaken to reduce the
amount of damage as much as possible. On receiving notice of a fault, the Product Manufacturer
will be under obligation to remove the fault, at his own option, either by providing adequate
repair services or by delivering a faultless product for replacement. No warranty will be accepted
in cases of natural wear (notably, wear and tear parts) or improper product handling.
The Product Manufacturer will refuse any liability in the event of damage resulting from faulty
operation, negligence, or unauthorized intervention into the product, notably, from the
replacement of product parts or the usage of accessory parts from other manufacturers. Any
such case will void the user’s claim for warranty.
Except for action, which is explicitly described in this User’s Guide, you are prohibited from
performing any kind of maintenance or repair work at the Pannoramic® DESK DW II. Only
3DHISTECH Service personnel or specifically authorized representatives are allowed to handle
repair work. In case of malfunction, contact the 3DHISTECH Service Support first.

PANNORAMIC® DESK DW II 3.0.4
TERMS AND ABBREVIATIONS
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Terms and Abbreviations
Term/Abbreviation
Description
CSV
Comma Separated Value
FOV
Field of View
NA
Numerical Aperture
Virtual Slide / Slide
A digital image of a thin glass plate on which specimens are mounted for microscopic
study:
a dynamic, interactive image that you can manage, save, magnify, zoom, name, evaluate,
annotate, mark, comment, send to a colleague electronically for co-operation or advice,
and so on.
Table 1: Terms and abbreviations

PANNORAMIC® DESK DW II 3.0.4
PRODUCT DESCRIPTION
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1Product Description
1.1 Product overview
1.1.1 Intended use
Pannoramic® DESK DW II is designed to use transmitted light to digitize biological samples
and specimens (histological sections, typically). The target users of the product can work
for example, in education, research, industrial, or medical sectors.
Warning!
After each scanning make sure to inspect the digital slide for over-exposed areas. If the slide
has been scanned based on improperly set parameters, it can highly affect the diagnostic
result because of information loss.
Warning!
Any modification to a hardware or software component of the PC will highly affect the
functionality of the scanner program.
1.1.2 Features and benefits
The Pannoramic® DESK DW II offers world class brightfield whole slide scanning. An
outstanding 0.12 µm/pixel resolution is achieved with the 40×/0.95 NA (equivalent to 80×
magnification) Plan-Apochromat objective.
Key features of the Pannoramic® DESK DW II Scanner are:
•Capable of scanning large slides
•3MP camera for barcode reading and preview image
•Improved permanent auto-focus
•Compact and robust device
•Good quality and stable manufacturing
The Pannoramic® DESK DW II is an entry-level half-automatic scanner with small footprint
and dimensions, low maintenance, simple and easy use. Optimal for those customers, who
want to begin with digitizing of their tissue samples and intend to use the scanner not for
batch processing (recommended daily scan quantity up to 10 slides).

PANNORAMIC® DESK DW II 3.0.4
PRODUCT DESCRIPTION
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1.1.3 Warning and information labels
The following figure contains the labels used on the Pannoramic® DESK DW II main unit and
the external mains power supply unit.
Figure 1 –Warning and information labels
Notice:
The symbol at the feeder slot calls attention to bio-hazardous materials in use.

PANNORAMIC® DESK DW II 3.0.4
PRODUCT DESCRIPTION
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1.1.4 Base unit
The following figure shows the main parts of the base unit.
Figure 2 –Main parts of the base unit
1. Protective cover
2. Sliding door
3. Point Grey Grasshopper 3 camera
1.2 System overview
The standard scope of delivery of the product includes the following hardware and
software items.
1.2.1 Pannoramic® DESK DW II system
The following figure shows the main components of the Pannoramic® DESK DW II system.

PANNORAMIC® DESK DW II 3.0.4
PRODUCT DESCRIPTION
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Figure 3: Pannoramic® DESK DW II system overview
1. 24V external power supply unit
2. Pannoramic® DESK DW II base unit
3. Monitor
4. Mouse
5. Control computer
6. Keyboard

PANNORAMIC® DESK DW II 3.0.4
PRODUCT DESCRIPTION
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1.2.2 Hardware options
The configuration of the control computer and monitor can vary depending on the product
order.
Camera
Camera
Description
Point Grey Grasshopper 3 Monochrome
1 CCD monochrome camera for normal brightfield scanning
Table 2: Camera
Camera adapters
Camera adapter
Description
0.63× adapter
(for Point Grey Grasshopper 3 only)
1× adapter
Table 3 –Camera adapter types

PANNORAMIC® DESK DW II 3.0.4
PRODUCT DESCRIPTION
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Warning!
The installation of the cameras in Pannoramic® DESK DW II must be carried out by trained
professionals! In any other case the warranty will be automatically voided. The supplier or
distributor is not liable for any damages caused by an installation carried out by an
unauthorized person.
Base Unit options
•Pannoramic® DESK DW II –Brightfield Option
Base unit equipped with Point Grey Grasshopper 3 camera for Brightfield scanning
Objectives
•Plan-Apochromat 20×/NA 0.8
•Plan-Apochromat 40× Corr/NA 0.95
Warning!
Do not change correction collar settings on 40×/NA objective, if you need it to be set,
contact customer service.
1.2.3 Control software
Pannoramic® Scanner 3.0.4 software
Optional (licensed features):
•Extended focus
•Z-stack
•Barcode reader
•Converter software (2.3.2 RTM), only available in Full scanner install mode
CaseViewer™software (fully functional)
Optional:
•CaseCenter™
•Pannoramic® Viewer TMA module
•3D Reconstruction module
•TumorBoard
•ESchool / Exam Module