3D Histech Pannoramic DESK User manual

PD1.18.1-UG-Rev1
Pannoramic DESK
1.18.1
User’s Guide
May 29, 2014
Rev. 1

Pannoramic DESK 1.18.1 User’s Guide
Contents
Disclaimer....................................................................................................................... 4
Declaration Of Conformity............................................................................................... 6
C aracter Formats and Symbols....................................................................................... 7
Notes Regarding Operational Safety................................................................................8
Notes on Warranty........................................................................................................ 10
Terms and Abbreviations............................................................................................... 11
1 Product Description.................................................................................................... 12
1.1 Product Overview....................................................................................................................12
1.1.1 Intended U e..................................................................................................................................................12
1.1.2 Feature and Benefit .....................................................................................................................................12
1.1.3 Warning and Information Label ....................................................................................................................13
1.1.4 Ba e Unit........................................................................................................................................................14
1.2 Sy tem Overview......................................................................................................................15
1.2.1 Pannoramic DESK y tem...............................................................................................................................15
1.2.2 Hardware Option ..........................................................................................................................................16
1.2.3 Control Software............................................................................................................................................17
2 Installation................................................................................................................. 19
2.1 Control computer port ...........................................................................................................19
2.2 Connector and cable .............................................................................................................20
3 Preparing Slides.......................................................................................................... 21
3.1 Affixing Barcode Sticker to Slide ...........................................................................................22
3.2 In erting and Removing Slide .................................................................................................23
4 Software Description.................................................................................................. 26
4.1 Starting / Exiting Pannoramic DESK Software Application......................................................26
4.1.1 Starting the oftware......................................................................................................................................26
4.1.2 Exiting the oftware........................................................................................................................................26
4.2 Option .....................................................................................................................................26
4.2.1 Barcode Setting .............................................................................................................................................27
4.2.2 Image Compen ation.....................................................................................................................................30
4.2.3 Micro cope Setting .......................................................................................................................................31
4.2.4 Event Call Setting ..........................................................................................................................................36
4.3 U ing Brightfield Manual Mode...............................................................................................39
4.3.1 Routine work tab............................................................................................................................................40
4.3.2 Scan Option window.....................................................................................................................................41
4.3.3 Preview tab.....................................................................................................................................................43
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Pannoramic DESK 1.18.1 User’s Guide
4.3.4 Preview area canned by preview camera.....................................................................................................46
4.3.5 Focu tab........................................................................................................................................................52
4.3.6 Service tab......................................................................................................................................................54
4.3.7 Di play field and toolbar for live image ........................................................................................................55
4.3.8 Start Scan........................................................................................................................................................57
4.4 Scan To Server..........................................................................................................................57
4.5 U ing Profile ...........................................................................................................................62
5 Troubles ooting and Maintenance..............................................................................63
5.1 Safety Information...................................................................................................................63
5.1.1 Cleaning the device........................................................................................................................................63
5.1.2 Preventive maintenance.................................................................................................................................64
5.2 Trouble hooting.......................................................................................................................64
5.3 Maintenance............................................................................................................................67
5.3.1 Removing the protective cover......................................................................................................................67
5.3.2 Replacing the halogen lamp...........................................................................................................................68
5.3.3 Removing a lide.............................................................................................................................................70
5.3.4 Tran porting Pannoramic DESK......................................................................................................................71
6 Tec nical Data............................................................................................................. 73
Index............................................................................................................................. 77
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Pannoramic DESK 1.18.1 User’s Guide
Disclaimer
Copyright © 2001-2014 3DHISTECH Ltd.
All right re erved.
Intellectual property related to the 3DHISTECH product are a follow :
EP 1,789,831; US 7,663,078; EP 2,024,772; JP 2009-512685; US 12/301,781; EP 1,644,767; JP 2007-
516451; US7,327,515; EP 1,994,398; JP 2008-557835; US 12/281,566; U0700210; US 6,246,785;
HU0900142; HU0700404; PCT/HU2007/000065; EP 08762668.5; US 12/663,537;
PCT/AT2006/000492; JP 2008-542552; EP 06817469; US 12/095,545; PCT/AT2006/000493; EP
06817470.5; US 12/095,596; HU0900741; US 61/264,732; US 11/826,752; P0401870;
PCT/IB2005/050344; US 11/662,976; HU0700409; US 12/042,050; US 77/636,144 and 007502032.
The above mentioned granted patent , granted utility model, regi tered trademark , pending
international and national patent application and the other corre ponding IP are the ole propertie
of the 3DHISTECH Ltd.
3DHISTECH Ltd. is not liable for damage of w atever nature (including, but not limited to, general
or specific damage, indirect damage, consequential damage or incidental damage, including t e
results of t e analysis of t e digitized slides, for example, c ange of ealt status related to
erroneous diagnosis from t e digitized slide(s)) t at stems from or is associated wit use of
Product, digitized slides, quality of staining, quality of stained slides, quality of used met od of
staining. 3DHISTECH Ltd. assumes no responsibility for t e functionality and fault-free condition of
your “application programs” (Workflows, VBA macros, Commander scripts).
CAUTION
Thi product ha not been approved or cleared a a medical device by the U.S. Food and Drug
Admini tration.
Do not u e thi device in clo e proximity to ource of trong electromagnetic radiation (e.g.
un hielded intentional RF ource ), a the e may interfere with the proper operation.
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Pannoramic DESK 1.18.1 User’s Guide
T ird-Party Disclaimer (LibTIFF – TIFF Library and Utilities)
3DHISTECH Ltd. i not liable for damage of whatever nature (including, but not limited to, general or
pecific damage, indirect damage, con equential damage or incidental damage, including damage
re ulting from lo t profit , interruption of bu ine , lo of bu ine information, pecuniary lo or
imilar damage) that tem from or i a ociated with the incorporated part of thi Product that i
made by Silicon Graphic Inc.
THE SOFTWARE IS PROVIDED “AS IS” AND WITHOUT WARRANTY OF ANY KIND, EXPRESSED,
IMPLIED OR OTHERWISE, INCLUDING WITHOUT LIMITATION, ANY WARRANTY OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE.
IN NO EVENT SHALL SAM LEFFLER OR SILICON GRAPHICS BE LIABLE FOR ANY SPECIAL, INCIDENTAL,
INDIRECT OR CONSEQUENTIAL DAMAGES OF ANY KIND, OR FOR ANY DAMAGES WHATSOEVER
RESULTING FROM LOSS OF USE, DATA OR PROFITS, WHETHER OR NOT ADVISED OF THE POSSIBILITY
OF DAMAGE, AND ON ANY THEORY OF LIABILITY, ARISING OUT OF OR IN CONNECTION WITH THE
USE OR PERFORMANCE OF THIS SOFTWARE.
Furt er Information
For the late t information on 3DHISTECH product and ervice , plea e vi it our web ite at the
following URL: http ://www.3dhi tech.com.
Company Addre : 29-33 Konkoly-Thege Miklo treet, Building 6
1121 Budape t – HUNGARY
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Pannoramic DESK 1.18.1 User’s Guide
Declaration Of Conformity
3DHISTECH Ltd. declare that the product Pannoramic DESK lide canner i de igned and produced
with con ideration of pecified requirement according to the ISO 13485:2003 and IEC 61326-2-
6:2005 tandard , and conform to the directive and other tandard li ted below:
IEC 61010-1:2001 (ed. 2), “Safety requirement for electrical equipment for mea urement, control,
and laboratory u e – Part 1: General requirement ”
IEC 61010-2-101:2002 (ed. 1), “Safety requirement for electrical equipment for mea urement,
control and laboratory u e – Part 2-101: Particular requirement for in vitro diagno tic (IVD) medical
equipment”
EN 55011:1998, Group 1, Cla A, “Limit and method of mea urement of radio di turbance
characteri tic of indu trial, cientific, and medical (ISM) radio-frequency equipment”
Thi product ha been te ted to the requirement of CAN/CSA-C22.2 No. 61010-1, econd
edition, including Amendment 1, or a later ver ion of the ame tandard incorporating the ame level
of te ting requirement .
Conformity with Directive 98/79/EC i marked by on the Pannoramic DESK device.
Conformity with Directive IEC 61010-2-101:2002 (ed. 1) i marked by on the product
labeling.
Further information may be obtained from the manufacturer:
3DHISTECH Ltd.
29-33 Konkoly-Thege Miklo treet, Building 6
1121 Budape t – HUNGARY
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Pannoramic DESK 1.18.1 User’s Guide
C aracter Formats and Symbols
Example Word or character that appear on the creen. The e include field name , creen
and window title , pu h-button and menu name , path or option .
Key on the keyboard. For example, function key ( uch a F11) or the Ctrl+M key
combination.
Example Cro -reference within thi document or to other document .
Warning! It might cau e irrever ible damage or harm to the u er of the product or the
product it elf if thi in truction i not followed.
Caution! It might cau e the product to not work properly if thi in truction i not followed
and alert to a potential danger ituation.
Note: Call attention to ome important feature .
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Pannoramic DESK 1.18.1 User’s Guide
Notes Regarding Operational Safety
The below ection of thi U er’ Guide contain information and warning of a kind that mu t be
followed by owner/operator per onnel.
Warning and advi ory ymbol which are u ed on the ba e unit of the Pannoramic DESK and in the
ection 1.1.3 Warning and Information Labels have the following meaning :
CAUTION
Di connect main plug before any kind of intervention into the device!
CAUTION
Cru h hazard!
The Pannoramic DESK, including any of it original acce ory component , hould not be operated in
any other way than de cribed in ection 1.1.1 Intended Use.
Any of the following note hould be trictly ob erved:
Caution!
In the event of any non-conforming type of u e, including non-conforming u e
of a emblie or ingle part , no liability will be a umed by the Manufacturer.
Thi hall al o apply to ervice or repair work of any kind, which i performed by
other than authorized ervice per onnel. All claim for warranty and warranty
ervice will be null and void in any uch ca e.
Warning!
In ert the power cord plug only into a grounding outlet. The protective action
mu t not be rendered ineffective by exten ion cable without protective
conductor. The Pannoramic DESK ha a built-in protection which mu t not be
rendered ineffective by exten ion cable without protective (earth-ground)
conductor.
Warning!
The operation of the in trument in explo ion-ri k environment i not allowed.
Warning!
If protective device are found to be ineffective, the Pannoramic DESK mu t be
hut down and precaution mu t be taken to prevent unintended u age. For
nece ary repair work or work to re tore proper operating condition, you
hould contact the 3DHISTECH Cu tomer Service.
Note:
Electric power to the Pannoramic DESK i upplied via an external main power
upply unit. It allow for operation at line voltage in the range of 100 V to 240
V ±10%, 50/60 Hz, without any extra facilitie required for voltage
tran formation.
Warning!
Check that your local line voltage i compatible with Pannoramic DESK
pecification before you turn power on.
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Pannoramic DESK 1.18.1 User’s Guide
Disconnect plug!
Remember to unplug the power cord before you open the Pannoramic DESK
device.
Warning!
Only connect external device that are afety extra low voltage rated to the
in trument to avoid the ri k of electrical hock.
Warning!
The Pannoramic DESK doe not include any pecial facilitie to protect from
ample with an etching, potentially infectiou , toxic, radioactive or other
health-damaging effect. You are under obligation to comply with all currently
binding legi lation, notably, national accident prevention rule when handling
ample of thi kind.
Caution!
Dirt or du t may adver ely impact the operating capability of the Pannoramic
DESK. For thi rea on, mea ure mu t be taken to eliminate uch influence to a
maximum po ible degree. During period of non-u e, the Pannoramic DESK
mu t be protected with a du t cover. Check that power i turned off before you
put the cover on.
Caution!
Avoid touching the lamp bulb. Di connect power plug and let the lamp cool
down for about 15 minute before replacing the lamp.
Crus azard!
Never open the front door unle prompted accordingly by oftware. When you
open the door at any other time, make ure not to reach with your hand into the
in trument to avoid the ri k of cru hing your finger .
Warning!
The front door i equipped with an interlock witch. If the door i opened while a
digitization proce i running, the proce will be topped in tantly.
Warning!
A defective Pannoramic DESK i not cla ified a dome tic wa te. It mu t be
properly di po ed in accordance with currently valid legal requirement .
Warning!
The Pannoramic DESK may not be operated by other than properly in tructed
per on . Operating per onnel mu t be fully aware of the potential danger
which a particular field of application involve . The Pannoramic DESK i a
preci ion in trument which may uffer a ignificant reduction in operational
function or even phy ical de truction following intervention performed in any
nonconforming manner.
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Pannoramic DESK 1.18.1 User’s Guide
Notes on Warranty
3DHISTECH Ltd. – a the Product Manufacturer – warrant the Pannoramic DESK to be free from
fault in material and workman hip at the moment of in tallation. Defect mu t be notified
immediately on identification and maximum effort mu t be undertaken in order to the amount of
damage a mall a po ible. On receiving notice of a fault, the Product Manufacturer will be under
obligation to remove the fault, at hi own option, either by providing adequate repair ervice or by
delivering a faultle product for replacement. No warranty will be accepted in ca e of natural wear
(notably, wear and tear part ) or improper product handling.
The Product Manufacturer will refu e any liability in the event of damage re ulting from faulty
operation, negligence or unauthorized intervention into the product, notably, from the replacement
of product part or the u age of acce ory part from other manufacturer . Any uch ca e will void
the u er’ claim for warranty.
Except for action which i explicitly de cribed in thi U er’ Guide, you are prohibited from
performing any kind of maintenance or repair work at the Pannoramic DESK. Only 3DHISTECH Service
per onnel or pecifically authorized repre entative are allowed to handle repair work. In ca e of
malfunction, contact the 3DHISTECH Service Support fir t.
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Pannoramic DESK 1.18.1 User’s Guide
Terms and Abbreviations
CSV Comma Separated Value
FOV Field of View
NA Numerical Aperture
Virtual Slide / Slide A digital image of a thin gla plate on which pecimen are mounted for
micro copic tudy:
a dynamic, interactive image that you can manage, ave, magnify, zoom, name,
evaluate, annotate, mark and comment, end to a colleague electronically for co-
operation or advice, and o on.
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Pannoramic DESK 1.18.1 User’s Guide 1 Product Description
1 Product Description
1.1 Product Overview
1.1.1 Intended Use
Pannoramic DESK i de igned to u e tran mitted light to digitize biological ample and pecimen
(hi tological ection , typically). The target u er of the product can work for example, in education,
re earch, indu trial, or medical ector .
Warning!
After each canning make ure to in pect the digital lide for over-expo ed
area . If the lide ha been canned ba ed on improperly et parameter , it can
highly affect the diagno tic re ult becau e of information lo .
Warning!
Any modification to a hardware or oftware component of the PC will highly
affect the functionality of the canner program.
1.1.2 Features and Benefits
The Pannoramic DESK offer world cla brightfield whole lide canning. An out tanding 0.12
µm/pixel re olution i achieved with the 40×/0.95 NA (equivalent to 80× magnification) Carl Zei
Plan-Apochromat objective.
Key feature of the Pannoramic DESK Scanner are:
•3MP camera for barcode reading and preview image
•Improved permanent auto-focu
•Compact and robu t device
•Good quality and table manufacturing
The Pannoramic DESK i an entry-level half-automatic canner with mall footprint and dimen ion ,
low maintenance, imple and ea y u e. Optimal for tho e cu tomer , who want to begin with
digitizing of their ti ue ample and intend to u e the canner not for batch proce ing
(recommended daily can quantity up to 10 lide ).
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Pannoramic DESK 1.18.1 User’s Guide 1 Product Description
1.1.3 Warning and Information Labels
The following figure contain the label u ed on the Pannoramic DESK main unit and the external
main power upply unit.
Figure 1 – Warning and information labels
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Pannoramic DESK 1.18.1 User’s Guide 1 Product Description
1.1.4 Base Unit
The following figure how the main part of the ba e unit.
Figure 2 – Main parts of the base unit
1. Protective cover
2. Protection rail
3. Scan camera
4. Sliding door
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Pannoramic DESK 1.18.1 User’s Guide 1 Product Description
1.2 System Overview
The tandard cope of delivery of the product include the following hardware and oftware item .
1.2.1 Pannoramic DESK system
The following figure how the main component of the Pannoramic DESK y tem.
Figure 3 – Pannoramic DESK s stem overview
1. 24 V external power upply unit
2. Pannoramic DESK ba e unit
3. Monitor
4. Mou e
5. Control computer
6. Keyboard
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Pannoramic DESK 1.18.1 User’s Guide 1 Product Description
1.2.2 Hardware Options
The configuration of the control computer and monitor can vary depending on the product order.
Cameras
Stingray F146C IRF Medical camera
1 CCD camera for normal brightfield application.
CIS VCC-FC60FR19CL
CMOS camera for high-quality brightfield
application allowing fa t canning.
Camera adapters
0.63× adapter 1× adapter 1.6× adapter
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Pannoramic DESK 1.18.1 User’s Guide 1 Product Description
Warning!
The in tallation of the camera in Pannoramic DESK mu t be carried out
by trained profe ional !
In any other ca e the warranty will be automatically voided.
The upplier or di tributor i not liable for any damage cau ed by an
in tallation carried out by an unauthorized per on.
Base Unit options
•Pannoramic DESK Ba ic Scan Option / Fa t Option – ba e unit equipped with Stingray F146C
IRF or CIS VCC-FC60FR19CL camera for Brightfield canning
Objectives
•Carl Zei Plan-Apochromat 20×/NA 0.8
•Carl Zei Plan-Apochromat 40× Corr/NA 0.95
Warning!
Do not change correction collar etting on 40×/NA objective, if you
need it to be et, contact cu tomer ervice.
1.2.3 Control Software
Pannoramic Scanner control software
Optional:
•Extended focu
•Z- tack
•Barcode reader (licen ed feature)
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Pannoramic DESK 1.18.1 User’s Guide 1 Product Description
Pannoramic Viewer software (fully functional)
Optional:
•Ca eCenter
•Pannoramic Viewer TMA module
•3D Recon truction module
•QuantCenter, Hi toQuant, NuclearQuant, MembraneQuant, and Den itoQuant module
•TumorBoard module
•E-School Encoder
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Pannoramic DESK 1.18.1 User’s Guide 2 Installation
2 Installation
Warning!
The in tallation of Pannoramic DESK mu t be carried out by a trained
profe ional!
In any other ca e the warranty will be automatically voided.
The upplier or di tributor i not liable for any damage cau ed by an
in tallation carried out by an unauthorized per on.
Only qualified ervice a i tant are allowed to in tall the hardware and oftware. The product i
ready for u e after in tallation.
2.1 Control computer ports
The following figure how the location of the connector in order to enable ea ier tran portation of
the product for a hort di tance, by di connecting cable and detaching hardware component from
each other.
Figure 4 – Ports on control computer
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Pannoramic DESK 1.18.1 User’s Guide 2 Installation
1. Statu di play
2. DVD drive (RW)
3. Power on/off button
4. Earphone and microphone 3.5mm Jack port
5. 2x USB port
6. Power upply connector
7. PS/2 mou e port
8. PS/2 keyboard port
9. 4x USB port
10. 2x USB port
11. Network port
12. Matrox Solio CameraLink port (for CIS camera)
13. 1x FireWire port (IEEE 1394 B for Stingray F146C camera)
2.2 Connectors and cables
•Control – USB cable (between canner and control computer)
•Preview camera – USB cable (between canner and control computer)
•Stingray – FireWire 1394 B cable (between Stingray camera and control computer)
•CIS – a pair of CameraLink cable (between CIS camera and control computer)
•Video cable (between monitor and control computer)
•Power upply cable (between 230V/110V and monitor)
•Power upply cable (between 230V/110V and control computer)
•Power upply cable (between 230V/110V and power upply unit)
•Power upply cable (between 230V/110V and CIS camera)
Warning!
Only connect external device that are afety extra low voltage rated to
the in trument to avoid the ri k of electrical hock.
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