3D Histech PANNORAMIC MIDI RX 1.0 User manual

PANNORAMIC® MIDI RX
1.0
USER’S GUIDE
FOR RESEARCH USE ONLY. NOT FORUSE IN DIAGNOSTIC PROCEDURES.
May 13, 2021 –Rev.1

PANNORAMIC® MIDI RX 1.0
CONTENTS
MAY 13, 2021
1
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Contents
Contents 1
Disclaimer 4
Declaration of Conformity 6
About this User's Guide 7
Character Formats and Symbols 8
Notes Regarding Operational Safety 9
Notes on Warranty 13
Terms and Abbreviations 14
1Product Description 15
1.1 Product Overview 15
1.1.1 Intended Use 15
1.1.2 Features and Benefits 15
1.1.3 Warning and Information Labels 17
1.1.4 Base Unit 18
1.2 System Overview 19
1.2.1 Pannoramic® MIDI RX system 19
1.2.2 Hardware Options 20
1.2.3 Control Software 22
2Installation 23
2.1 Operation System of the Control Computer 23
2.2 Control Computer Ports 25
2.3 Connectors and Cables 26
2.4 Coupling the Lumencor SOLA unit with the scanner 26
2.5 Coupling the Lumencor Spectra 6 Unit with the Scanner 27
2.6 External Power Supply Unit 28
2.7 Power the Scanner On/Off 28
3Preparing Slides and Trays 29
3.1 Affixing Barcode Stickers to Slides 31
3.2 Inserting and Removing Slides 32
3.3 Inserting and Removing the Tray 33
4Software Description 35
4.1 Starting/Exiting Pannoramic® Scanner Software for Research 35
4.1.1 Starting theControl Software 35

PANNORAMIC® MIDI RX 1.0
CONTENTS
MAY 13, 2021
2
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
4.1.2 Exiting Pannoramic® Scanner Software for Research control software 35
4.2 Main Window Functions 36
4.3 Hotkeys 53
5Scanning Modes and Settings 55
5.1 Brightfield Scanning Mode 55
5.1.1 Profile Settings Panel 56
5.1.2 MicroscopeControl Panel 63
5.1.3 Quick Preview Functions 74
5.1.4 Quick Microscope Functions 74
5.2 Fluorescence Microscope Mode 76
5.2.1 Profile Settings Panel 76
5.2.2 Microscope Control Panel 86
5.2.3 Quick Preview Functions 98
5.2.4 Bottom Menu Bar of the Main Window 101
5.3 Planner Mode 102
5.3.1 General Functions at the Main Menu 102
5.3.2 General Functions at the Tray Menu 105
5.3.3 General Functions at the Slide Menu 105
5.3.4 Slide View with Card 107
5.3.5 Table View Mode 110
5.3.6 Card Collection View Mode 111
5.4 Profile and Preview Overview on the Planner 111
5.5 Progress Features 112
6Settings and Services 113
6.1 Settings 113
6.2 Services 123
7Point Spread Function 132
8Using Profiles 134
9Troubleshooting and Maintenance 136
9.1 Activation of the Control Software 136
9.2 Recovery Functions 141
9.3 Safety Information 141
9.3.1 Cleaning the Device 143
9.3.2 Cleaning the Trays 143

PANNORAMIC® MIDI RX 1.0
CONTENTS
MAY 13, 2021
3
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
9.3.3 Preventive Maintenance 143
9.4 Troubleshooting 143
9.4.1 Fluorescent Applications (Optional) 145
9.5 Maintenance 146
9.5.1 Opening the Protective Covers 146
9.5.2 Removing a Slide 147
9.5.3 Installing and Removing the Filter Module (Fluorescent Option) 148
9.5.4 Transporting Pannoramic® MIDI RX 149
10 Technical Data 151

PANNORAMIC® MIDI RX 1.0
DISCLAIMER
MAY 13, 2021
4
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Disclaimer
Copyright © 2001-20213DHISTECH Ltd.
All rights reserved.
Intellectual property related to the 3DHISTECH products are as follows:
•P1300124;PCT/HU2014/000020; EP 14745228.8.;US 14/771.380
•P0700404;PCT/HU2008/000065;EP 08762668.5.;US12/663.537
•P1700279; PCT/HU2018/050030
•P1700483
•P1500394;PCT/HU2016/050039; EP 16840280.8.; US15/756.370
•P0700409; US2008/0306964
•P0800181;PCT/HU2009/000027; EP 09721248.4.
•P0600435;PCT/HU2007/000047;EP 2024772;US12/301.781
•P0600177;PCT/HU2007/000018; EP 1.994.398;US12/281.566
•P0900741; PCT/HU2010/000130;EP 10812989.1.
•P0900142; PCT/HU2010/000027;EP 10726183.6
•P101036; PCT/IB2005/050351;EP 1789831; US 7.663.078
•P0301911; PCT/HU04/00019;EP 1644767; US 7327515
The above-mentioned grantedpatents,grantedutility model, registered trademarks, pending
international and national patent applications and the other corresponding IP are the sole
properties of the 3DHISTECH Ltd.
3DHISTECH Ltd. is not liable for damage of whatevernature (including, but not limited to,
general or specific damage, indirect damage, consequentialdamage or incidental damage,
includingthe results of the analysis of the digitizedslides, forexample, change of health status
related to erroneous diagnosis from the digitized slide(s)) that stems from oris associated with
use of Product, digitized slides, quality of staining,quality of stainedslides, qualityof used
method of staining.3DHISTECHLtd. assumesno responsibility forthe functionalityand fault-
free condition of your “application programs” (Workflows, VBA macros, Commander scripts).

PANNORAMIC® MIDI RX 1.0
DISCLAIMER
MAY 13, 2021
5
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
CAUTION
For Research Use Only. Not for use in diagnosticprocedures. This product has not been approved
or cleared as a medicaldevice by theU.S. Food and Drug Administration.
Do not usethis device in close proximity to sources of strong electromagneticradiation (e.g.,
unshielded intentional RF sources),as these may interferewith the proper operation.
Third-party disclaimer
3DHISTECH Ltd. is not liable for damage of whatever nature (including, but not limited to, general
or specificdamage, indirect damage, consequentialdamage or incidentaldamage,including
damage resulting fromlost profits, interruptionof business,loss of business information,
pecuniary loss or similar damage) that stems fromor is associated with the incorporated part of
this Product that is made by a third-party company.
THE SOFTWARE IS PROVIDED “AS IS” AND WITHOUT WARRANTY OF ANY KIND, EXPRESSED,
IMPLIEDOR OTHERWISE, INCLUDING WITHOUTLIMITATION, ANY WARRANTY OF
MERCHANTABILITY OR FITNESS FOR A PARTICULARPURPOSE.
FurtherInformation
For the latest information on 3DHISTECH products and services, please visit our website at the
following URL: http://www.3dhistech.com.
Company Address
3 Öv Street, 1141 Budapest –HUNGARY

PANNORAMIC® MIDI RX 1.0
DECLARATION OF CONFORMITY
MAY 13, 2021
6
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Declaration of Conformity
3DHISTECH Ltd. declares that the productPannoramic® MIDI RX slidescanner is designedand
produced with considerationof specified requirements according to theIEC 61326-2-6:2012
standard, and conformsto the directives and otherstandards listed below:
IEC 61010-1:2010, “Safety Requirements for Electrical Equipment for Measurement, Control, and
Laboratory Use –Part 1: General Requirements”
IEC 61010-2-081:2015,“Particular requirements for automatic and semi-automaticlaboratory
equipment for analysis andother purposes"
Further informationmaybe obtained from the manufacturer:
3DHISTECH Ltd.
3 Öv Street
1141 Budapest –HUNGARY

PANNORAMIC® MIDI RX 1.0
ABOUT THIS USER'S GUIDE
MAY 13, 2021
7
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
About this User's Guide
The purposeof this manual is to assist the user in the safe and reliable operation of the product
described. Before operating thedevice, you must carefully read this instructionmanual, and
adhereto all WARNING and CAUTION notices (refer to chapter 6 Notes RegardingOperational
Safety for more information), anda copy should be kept in the close to the scanner for reference
whenever required.
This User's Guide is a part of the Pannoramic® MIDI RX systemidentified by the relevant article
numbers included in the 3DHISTECH OrderingGuide.

PANNORAMIC® MIDI RX 1.0
CHARACTER FORMATS AND SYMBOLS
MAY 13, 2021
8
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Character Formats and Symbols
The following character formats and symbols callyour attentionin this manual:
Example(text in bold)
Words or characters that appear on the screen. Theseinclude field names, screen and window
titles, push-buttonand menu names, paths or options.Keys on the keyboard.For example,
function keys (such as F11) or the Ctrl+S hotkey.
Example (textin bold and italics)
Cross-references withinthis document or to other documents.
Warning!
It might cause irreversible damage or harmto the user of the product or the product itself if
this instruction is not followed.
Caution!
It might cause the product to not work properly if this instruction is not followed and alerts
to a potential danger situation.
Notice:
Calls attention to some important features.

PANNORAMIC® MIDI RX 1.0
NOTES REGARDING OPERATIONAL SAFETY
MAY 13, 2021
9
FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES.
Notes Regarding Operational Safety
The below section of this User’s Guide contains information andwarnings of a kind that must be
followed by owner/operator personnel.
Warning and advisorysymbols which are used on the base unit of the Pannoramic® MIDI RX and
in section 1.1.3 Warningand InformationLabels have the following meanings:
Warning!
Disconnect mains plug! Remember to unplug the power cord before you open the
Pannoramic® MIDI RX mainunit for maintenance.
Crush hazard! Thereis crush hazard in themovement area of theslide tray during
operation. Please note that the digitizing process has to be interrupted and the tray moved
via the software to the output position before removing it.
The Pannoramic® MIDI RX, includingany of its original accessory components, shouldnot be
operated in any other way than described in chapter 1.1.1 IntendedUse.
Any of the following notesshould bestrictly observed:
Warning!
If operating the deviceother than specified by the manufacturer,the levelof safety will
decrease.
Warning!
Insert the power cord plugs only into a groundingoutlet. The protective action must not be
rendered ineffective by extension cables without protective conductor. The Pannoramic®
MIDI RX has a built-in protection which must not berendered ineffectiveby extension
cables without protective (earth-ground) conductor.