Bertin Technologies PRECELLYS 24 Touch User manual

PRECELLYS®
24 Touch
WWW.BERTINTECHNOLOGIES.COM
USER MANUAL
PRECELLYS®24 Touch

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PRECELLYS®24 Touch
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USER MANUAL
PRECELLYSEVOLUTION
BERTIN TECHNOLOGIES
Parc d’activités du Pas du Lac
10 bis, avenue Ampère
78180 Montigny le Bretonneux
France
Tél : + 33 (0)1 39 30 61 60
Precellys is a registered trademark of Bertin Technologies.
© 2023 Bertin Technologies All rights reserved
Original instructions.
Document reference: 022012-800-DU001-C
DISCLAIMER
Bertin Technologies and/or its subsidiaries disclaim all liability relating to
this document, either explicitly or implicitly, including, but not limited to
commercial warranties or specic warranties.
Unless the law provides otherwise, neither Bertin Technologies nor its
subsidiaries shall be held liable, under tort or contract, and regarding
guarantees, or any system whatsoever, for any damage whatsoever, inclu-
ding, but not limited to, during the use of this document.
Neither Bertin Technologies nor its employees shall be held liable for
losses and costs resulting from this use.
The information in this document is designed only for use with this Bertin
Technologies product. Bertin Technologies is not liable of any use of this
information that is applied to other products.
Bertin Technologies reserves the right to revise this document and to
make changes from time to time without prior notice.
This limitation clause is governed and interpreted in accordance with
French law. Any dispute relating to the content of this clause falls under
the exclusive jurisdiction of the Courts of Paris, France.
OWNERSHIP AND CONFIDENTIALITY
The information, studies, plans and diagrams contained in this document
remain the property of Bertin Technologies and are condential.
The information contained in this document may not be used, in whole
or in part, or disclosed or reproduced without the prior consent of Bertin
Technologies.
CONTENTS
1. INTRODUCTION
2. PRECAUTIONS AND RECOMMENDATIONS
2.1. Safety symbols
2.2. Recap of the directions for use
2.3. Risk of electric shock
2.4. Biological hazards
2.5. Non-ionising radiation
2.6. Risk of use
3. DESCRIPTION OF THE PRECELLYS® 24 TOUCH
3.1. Presentation of the equipment
3.2. Characteristics
3.3. Noise level
3.4. Warranty
3.5. Manufacturer’s Address
3.6. Technical assistance
3.7. Standardisation requirements
3.8. Machine reference
4. TRANSPORT AND STORAGE
4.1. Transport
4.2. Storage
5. INSTALLATION
5.1. Unpacking the device
5.2. Installation and connection
6. INSTRUCTIONS
6.1. Preparing samples
6.2. Launching a grinding protocol
7. ALARMS
8. CLEANING AND DISINFECTION
8.1. Recommandations
8.2. Disinfection protocol
9. MAINTENANCE AND SERVICING
9.1. Repair
9.2. Problems encountered
9.3. Replacing wear parts
9.4. Support
10. ELIMINATION
APPENDICES
11.1. Electrical diagram
11.2. Precellys® returns®

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Lire attentivement la notice
Ne pas ouvrir le capot lors du fonctionnement.
Do not open the cover while running.
2 PRECAUTIONS AND RECOMMENDATIONS
This manual must be read carefully by the user before any use of the
Precellys® 24 Touch cell lyser/homogeniser.
Handling this device without following the instructions set out in this
manual could reduce the level of protection provided by the device.
In the event of non-compliance with the safety instructions set out in
this document, Bertin Technologies disclaims all liability for any resulting
damage to property or physical injury.
Contact the local distributor immediately if there is any doubt as to the
safety of the appliance.
2.1. Safety symbols
The following symbols can be found in various places on the device.
Follow the instructions associated with these symbols
The equipment may only be repaired by personnel who have been
authorised by the dealer or manufacturer.
The waste resulting from normal analysis operations must be disposed of in
biological bins and treated by specialised companies.
1. INTRODUCTION
Thank you for purchasing a Precellys® 24 Touch by Bertin Instruments.
Precellys® 24 Touch is a universal tissue homogeniser that is both intuitive
to use and eective such that it can be adapted for routine or R&D
projects.
The Precellys® 24 Touch can homogenise a large number of dierent
samples in between a few seconds and two minutes.
It has a patented automatic tube locking system that uses a vacuum
called «Press and Block» which makes the Precellys® 24 Touch safe and
easy to handle. Developed in the eld of Life Sciences, the Precellys®
24 Touch is compatible with work environments up to biosafety level 3
(BSL3). The instruments in the Precellys® range are used by thousands of
scientists around the world. The instrument’s unique 3D motion delivers
the same high level of energy and eective homogenisation to each tube.
The Precellys® 24 Touch can process up to 24 tubes simultaneously.
This manual presents all the information needed for the unpacking,
installation, routine use and maintenance of the Precellys® 24 Touch.
The product’s technical specications and the following information are
subject to change without notice.
The sticker with the «Biohazards» symbol is delivered with the
device and must be stuck on the front of the device for use with
potentially infectious samples.
Heavy load hazard: there is a heavy load sticker on the packaging
of the equipment. The Precellys® 24 Touch should be carried by
two operators, preferably. Safety shoes must be worn by the
operator during transportation.
High temperature hazard: this sticker warns about a hot surface.
The maintenance operator must wait at least 60 minutes after
the end of a cycle before carrying out work on the equipment.

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Electrical hazard: before any maintenance operation, the
operator must disconnect the mains supply.
Only use the device with the type of electrical power source
indicated on the label.
Do not pull on the cords. Hold the plug and not the cable when
plugging in or unplugging the cord.
Do not expose the device to sudden variations in temperature
and humidity, avoid knocks, and only use it indoors.
Do not immerse the device, do not use the device in explosive
atmospheres or in wet environments.
Do not disassemble or repair this power supply yourself. There
is a risk of electrocution.
Unplug the cord from the wall outlet before cleaning it.
Disconnecting the power cord from the device cuts o the
power supply to the device.
Do not put the device in a place where it would be dicult to
operate the disconnecting procedure.
2.2. Recap of the directions for use
2.2. Rappel des conseils d’utilisation du bloc alimentation
If the system does not start, the operator should
contact the manufacturer
Failure to follow the instructions associated with the
symbol may result in physical injury and environmental
damage.
2.3 Risk of electric shock
Although the device is perfectly insulated and earthed, it is important
that all users are made aware of the risks associated with the use of liquids
near an electrical power supply. If a liquid is spilled, the device must be
immediately disconnected from the power supply by unplugging the
mains plug even if the device is in operation. The device should then be
dried and any spilled liquid should be wiped up.
To avoid any risk of an electric shock, the device’s power supply must be
connected to an installation that complies with the standards in force.
2.6 Risk of use
2.6.1 Using the grinding kits
Depending on the user settings (speed, number of cycles, duration of
a cycle, time delay between two cycles) of the Precellys® 24 Touch, the
grinding tubes may get very hot leading to sudden damage.
For the Precellys® 24 Touch to work properly, it is strongly recommended to
use the grinding tubes supplied by Bertin Technologies and keep within the
operating limits dened for each grinding kit. These operating limits specify
the maximum levels of the settings (speed, number of cycles, duration of a
cycle, time delay between two cycles, etc.) that should not be exceeded for
the biological samples to be prepared correctly.
The operating limits of the lysing kits are available on the www.bertin-
technologies.com website.
- Do not plug the device back in until it has been
checked.
- The casing must not be removed by the operator
under any circumstances - Risk of electrocution.
2.3.1 Fuse
The device contains 2 external fuses located on the rear panel. If they need to
be changed, they must be replaced with a fuse reference 5x20 - T 6.3 A - L 250
V. It can be easily replaced by the user, see §4.2 Installation and connection.
Wear gloves when handling samples and take all necessary precautions to
prevent any risk of contamination. Use the best practices implemented in
your laboratory.
2.5. Non-ionising radiation
WARNING:
This device is a Class A device. In a residential environment, this device
may cause radio interference. In this case, the user should take appropriate
measures.
2.4 Biological hazards
Protective glasses Gloves

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3.1.2 Tube kinetics
Given the design and symmetry of the machine, each of the tubes of the
same type placed in the tube holder has strictly the same kinetics, which
guarantees the same quality of lysis and homogenisation in each of the
tubes.
The centre of gravity of the tubes moves through a complex hemispherical-
shaped pathway. The mixture contained in the tubes therefore undergoes
a three-dimensional motion that prioritises vertical movements, thereby
ensuring the eciency of the lysis. The movement generated by the
Precellys® 24 Touch is a precessional motion, which means that the tubes
are not rotated.
The geometry of the tubes used must be compatible with the tube holder
and be able to withstand accelerations of 600 g for 5 minutes without
becoming deformed (see recommendations for use § 1.1.1).
The precessional motion undergone by the biological samples causes the
temperature of the sample and apparatus to rise.
3.1.3 Description of the equipment
1
2
3
2.6.2 Incorrect operation
Handling this device without following the instructions set out in this
manual could reduce the level of protection provided by the device.
3 DESCRIPTION OF THE PRECELLYS® 24 TOUCH
3.1 Presentation of the equipment
3.1.1 Instrument
The Precellys® 24 Touch is a device designed to lyse and homogenise
biological samples contained in tubes at variable speeds, in order to
extract proteins, nucleic acids, drugs, etc. It simultaneously processes
tubes at high speed which may contain several millilitres of sample (see
the range of tubes oered at www.bertin-technologies.com.
Main advantages of the Precellys® 24 Touch:
Do not tilt the device: the Precellys® 24 Touch must always be
resting on its four feet. If not, the internal components can get
damaged or the plastic casing will break.
Do not handle the instrument if the casing is partially or
completely disassembled or if it is damaged; the levels of the
voltages in the device are hazardous.
Do not handle the instrument if the earth connection has been
disconnected.
Do not install any unauthorised boards, components or
accessories; this could aect the protection provided by the
device and will void the warranty.
Check that the supply voltage specied on the rear panel of the
device matches the voltage of the power supply.
Do not immerse the device
Bertin Technologies shall be exempt from any claim for
compensation for any damage to property or physical injury
resulting from a non-compliance with the safety instructions
set out in this document.
Easy tube loading: innovative and automated locking system.
Easy to disinfect: the areas to be cleaned are very easily
accessible.
Flexible and easy programming cycles (cycle time, speed).
No degradation of the biological material and no cross-
contamination.
Eective and identical grinding in all the tubes
Lid: closes the equipment.
Locking handle:
locks the Precellys® 24 Touch lid and
prevents it from opening.
Human Machine Interface:
programs and starts the cycles.
1
2
3

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4
8
9
12
11
10
5
6
7
Figure 1: home screen
3.1.4 Presentation of the command interface
The touch screen lights up when the Precellys® 24 Touch is powered on and
displays the main menu the system has booted (a few seconds).
Blocking plate: keeps the lysis tubes inserted in the tube
holder.
Tubes: tubes containing the samples.
Tube holder: holds the lysis tubes.
Containment seal: seals the Precellys® 24 Touch.
Air inlet: diuses the air in the Precellys® 24 Touch.
USB port: exports/imports data using a USB stick.
On/O button: turns the Precellys® 24 Touch on and o.
Power plug: connects the Precelly® 24 Touch to the power
supply.
Fuse: protects the Precellys® 24 Touch from power surges.
4
5
6
7
8
9
10
12
11
3.1.3 Description of the equipment
3.1.4.1 Programming
The Precellys® 24 Touch is designed to operate at a maximum speed of 6800
rpm.
A Precellys® 24 Touch operating cycle is made up of several successive runs
between which the lid must not be opened: a stepped cycle that is broken
down into a number of runs performed for a certain period.
The speed as well as the other settings which dene a stepped cycle can be
modied in both programs:
Settings: Adjustment interval
Speed: 4500 to 6800 rpm in 100 rpm increments
Number of periods: 1 to 10

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3.1.4.3 Setting up the cycles of the Precellys® 24 Touch
The Precellys® 24 Touch operates at a maximum speed of 6800 rpm.
A homogenisation protocol for a Precellys® 24 Touch is made up of one or
more steps between which the lid must not be opened.
The Speed and other settings can be set using the touch screen.
In order to program a homogenisation cycle, press the Cycle Setup icon on
the home screen. The screen below then appears:
1. Click on the icon to choose the setting that you want to modify
2. An adjustment bar appears on the right of the screen
3. Change the value by dragging the slider from right to left
The operator is responsible for the settings of the equipment. For each
lysing kit, the manufacturer recommends ranges of settings.
Note: To prevent the motor from overheating during a long grinding
phase, the Precellys® 24 Touch has a safety system that prevents the
device from running when the motor temperatures are too high.
Should this occur, let the device cool down before using it.
1
2
3
Access to the settings
of the device
The operating protocol is under the responsibility of the operator. The
manufacturer recommends an operating range for each kit that prevents
the device from getting too hot.
For high speed use, reduce the times of each period and leave the unit
to cool down between two cycles (approximately 2 minutes). A thermal
safety device protects the device and prevents its use in the event of
overheating.
3.1.4.2 Description of the command interface
Screen: displays all the information relating to the settings and
faults of the equipment
Start/pause button: starts and stops the cycle.
LED: indicates the status of the equipment
• green: equipment operational and ready to start a cycle
• red: alarms
Access to the cycle
settings
Access to the list of
saved cycles
1
2
3
Protocol settings Icon Values
Speed 4500 to 6800 rpm
in 100 rpm increments
Grinding time 5 to 90 s
Pause time 5 to 120 s
Number of grinding steps 1 to 10
Duration of the period: 5 to 90 s in increments of 1 second
Time delay between 2 periods: 5 to 120 s in increments of 1
second

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PRECELLYS®24 Touch USER MANUAL
Technical characteristics
Supply voltage and
frequency
230 V ~ -240 V ~- 50 Hz (EU standard)
100 V~ - 120 V~ - 60 Hz (US standard)
Consumption <1 kVA
Fuse 2x – 5x20 – T 6.3A – L 250
Safety Class I device
Physical characteristics
Width 287 mm
Depth 408 mm
Height 390 mm (515 mm with the lid open)
Mass 23 kg
Temperature of use and
storage 15-30°C
Humidity 50-85% RH
Altitude <2,000 m
Noise <70 dB
Pollution level No. 2: standard environment
Operating characteristics
Speed 4500 – 6800 rpm
Number of periods 1 - 10
Duration of period 10 – 90 secondes
Time delay between two
periods 1 – 120 secondes
3.1.4.4 Maintenance
The Precellys® 24 Touch is made up of wear parts that must be replaced at
least once a year or before if wear can be observed because of intensive
use.
For any other problem, refer to paragraph 9.2 or contact your local dealer.
3.2 Characteristics
3.3 Noise level
In normal operation (rotation at 6800 rpm), the device emits a noise level of
less than 70 dB.
3.4 Warranty
Bertin Technologies warrants that the equipment is free of defects when
it is shipped.
This warranty is limited to a period of one (1) year and does not include
the following parts: fuses, anti-rotation kit, vacuum and containment
seals and blocking plate.
This warranty begins when the equipment is installed and registered
online on the www.bertin-instruments.com website.
It does not apply in the following cases:
3.5 Manufacturer’s Address
Bertin Technologies
Parc d’activité du Pas du Lac
10bis Avenue Ampère
78180 MONTIGNY-LE-BRETONNEUX
France
3.6 Technical assistance
If you cannot resolve a problem after reading this manual, contact the
local oce of your dealer.
User interface
Keyboard 1 push button
Display 1 x 5-inch LCD capacitive touchscreen
1 indicator (green and red)
Capacity
Number of tubes 24
Total volume of a tube 0.5 ml/2 ml
The equipment has not been installed, operated or maintained
in accordance with the instructions described in this manual.
The equipment has been repaired or altered by unqualied
personnel.
The serial number of the equipment is damaged or removed.

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PRECELLYS®24 Touch USER MANUAL
3.7 Standardisation requirements
This equipment complies with CE marking requirements.
3.7.1 Intensive operation
If the device is used intensively (high speed, long cycle times, full tube
load, sequenced cycles), the normal rise in the overall temperature of
the system may trigger the thermal safety device. In this case, the power
supply to the motor is automatically cut o in order to prevent the device
from overheating.
3.8 Référence de la machine
Reference of the Precellys® 24 Touch: P002391-P24T0-A.0.
4 TRANSPORT AND STORAGE
4.1 Transport
Avoid violent shocks which could make the device not work properly.
Do the following each time you transport the device:
1- Reposition the tube holder locking foam
2- Close the lid
3- Use the items from the original packaging.
4.2 Stockage
The device must be stored in a dry place and at a temperature between 0°C and
50°C.
5 INSTALLATION
5.1 Unpacking the device
1. Check the contents of the box using the following list:
- 1 user manual (French/English)
- 1 Precellys® 24 Touch
Should the delivery be incomplete, contact your local dealer immediately.
* A suitable adapter or cable (not supplied) is required in countries using power
outlets other than: Europe, United Kingdom, United States, Switzerland and
Australia.
mains cable *
1 blocking plate
2 vacuum seals (including 1 in place on the machine)
2 mains fuses (including 1 in place on the machine)
1 individual quality control form
1 CE certicate
1 manufacturer’s inspection certicate
Do not connect the device to the power supply until
you have completed the installation.
Do not tilt the device: the Precellys® 24 Touch must
always be level and resting on its four feet. If not, the
internal components will get damaged or the plastic
casing will break.

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Figure 2: Instructions for adap-
ting the device to the electric
current (220V/110V)
Handle
2.Carefully remove the Precellys® 24 Touch from its box and place it on a
clean, horizontal and stable work surface (weight of the device = 23 kg):
the height of the 4 feet can be adjusted in order to make the equipment
more stable.
Given its mass, the device should preferably be handled by two operators
3.Check its external appearance. Immediately report any defect to the
carrier.
4. Keep the original carton, protective foam pads and documentation:
these items will be needed in the event of a return.
Do not lift the device by holding the lid when
removing it from its box. It must be lifted either using
the extraction handles provided or by holding the
equipment from underneath at the notches provided
on the side of the casing (see paragraph 2.2). There are
also notches provided in the protective foam.
In the event of a signicant temperature dierence
between the storage area and the laboratory, allow
the device to return to room temperature to avoid any
condensation.
5.2 Installation and connection
1. Remove the foam padding from the tube holder and replace the
containment seal if necessary (see § 8.3.2).
2. Fit the vacuum seal (see § 8.3.1).
3. Check that the technical characteristics of the device provided in this
manual are consistent with the voltage of your power supply (see § 2.1).
Keep the foam padding, which must be put back in
place before transporting the device. If the device is
returned to the dealer or manufacturer without this
protection, the warranty will not apply.
The containment seal must be tted in accordance with
the instructions in this manual in order to adequately
protect the operator. Indeed, the containment seal is
an important element of the system used to contain
the electrical parts of the device and protect them
from getting sprayed by liquids.
Before connecting the power cord to the device, check
the indicated rating on the white window of the fuse
holder. Make sure your power supply matches the
rating displayed on the window. If not, remove the fuse
holder under the power supply, remove the seat of one
of the fuses, reverse its position and replace the fuse
holder by snapping it into place.

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If this verication is not done and the rating indicated
on the fuse holder is 220V when it is connected to
a 110V electric current, the device will not start.
Conversely, if the rating indicated on the fuse holder
is 110V and it is connected to a 220V electrical current,
this could have serious consequences for the user and
the device. Check that the fuse tted in the holder has
a rating of 6.3A.
Using an incompatible power supply can irreversibly
damage the electronics of the device.
Leave about 10 cm of clearance around the air inlets
and outlets.
This device must be powered by a mains outlet with a
protective earth terminal.
Wearing gloves and taking all necessary precautions
according to the risk of infection are recommended
when using the device and handling samples.
4. Check that the air intake of the fan and the base of the casing are
unobstructed: the air outlet is located under the device.
5. Connect the Precellys® 24 Touch to the mains power using the
appropriate mains cable.
6 INSTRUCTIONS
6.1 Preparing samples
The samples must be prepared in the lysing kits recommended by Bertin
Technologies listed on the www.bertin-technologies.com website.
Only the lysing kits recommended by Bertin Technologies should be used.
Using any other accessories may reduce the level of protection provided
by the device.
6.2 Launching a grinding protocol
6.2.1 Switching on the equipment
After connecting the device, the power is turned on using the On/O switch
located on the rear panel, near the power cable terminal.
A few seconds after starting the device, the main menu is displayed. The
operator can choose a stored program from the library or program the cycle
directly in the cycle setup page.
6.2.2 Opening the lid
To open the lid: lift the locking handle and tilt the lid as far as the rear limit
stop.
6.2.3 Loading the tubes
The tubes containing the samples are held in the tube holder by the collar,
and are retained by the blocking plate that must be removed to load or
unload the tubes.
A vacuum system keeps the blocking plate pressed down on the tube
holder. The branches of the blocking plate hold the tubes in place when this
system is activated (at the start of a cycle), and release them when there is
no longer any vacuum (a few seconds after stopping a cycle).
6.2.4 Closing the lid
Tilt the lid until the locking handle engages in its clasp.
6.2.5 Running a grinding protocol
After conrming the start of a grinding protocol with the «Start» button,
the vacuum system lowers the blocking plate.
When the tubes are correctly locked in place (when the pressure is low
enough), the protocol begins and the green light ashes.
The timer (in minutes and seconds) displays the time remaining before the
complete end of the programmed protocol.
Never open the lid if the tube holder is in motion.
If the lid is opened during a grinding protocol, the
protocol is automatically stopped.

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6.2.6 End of the grinding protocol
At the end of a grinding protocol, the system returns to the «Use» menu.
The vacuum under the blocking plate stops a few seconds after the
system stops: the blocking plate cannot be removed from the tube holder
during this period.
Note: The time and speed cannot be changed when it is running.
6.2.7 Stopping the grinding protocol
During the course of the cycle, the user can stop the current cycle at any
time by pressing the «Stop» button.
After the user has stopped the cycle, the display shows the remaining
time of the grinding protocol. The «STOP» or «START» button can be
pressed to return to the «Start» menu. The vacuum under the blocking
plate stops a few seconds after the system stops: the blocking plate
cannot be removed from the tube holder during this period.
6.2.8 Operating limits of the grinding kits
The lysing kits oered by Bertin Technologies must be used within the
operating limits indicated on the www.bertin-instruments.fr website
7 ALARMS
The list of the main problems which can occur during operation and the
measures to resolve them are set out in the following table:
Wait for the system to come to a complete stop before
opening the lid.
Wait for the system to come to a complete stop before
opening the lid.
Using the lysing kits beyond the operating limits can
lead to the sudden deterioration of the tubes.
Alarm messages Possible cause(s) Remedial measures
The tubes recommended by Bertin
Technologies are incorrectly posi-
tioned on the tube holder
1. Reposition the tubes.
2. Press in the centre of the blocking
plate during the vacuum process
(lid open).
The blocking plate or the tube hol-
der is positioned incorrectly.
Put the blocking plate or tube holder
back in position on the tube holder,
making sure that the blocking
plate is correctly guided by the
mistake-proong key.
The vacuum seal is incorrectly
positioned.
Put the vacuum seal back in place on
the tube holder making sure the seal
is sitting properly inside the groove
of the tube holder.
The blocking plate is damaged. Replace the blocking plate
The vacuum seal is damaged. Replace the vacuum seal.
The vacuum circuit is defective. 1. Switch o the device.
2. Contact the technical support.
The lid is not properly closed.
1. Check that nothing is preventing
the lid from closing.
2. Press the lid down and make sure
that the locking handle is properly
engaged in the clasp of the housing.
The detection system is defective.
1. Switch o the device.
2. Contact the technical support.
Pressure error
Lid error
Before any maintenance and servicing operation, the
device must be cleaned and disinfected in accordance
with the risk of infection associated with the samples
treated and with the protective equipment required by
the rules in force. After any maintenance and servicing
operation, check that the device is safe.

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Messages d’alarme Cause(s) possible(s) Action(s) à mener
The temperature of the motor has
reached its safe limit.
1. Leave the device on so that the
ventilation system can operate.
2. Make sure that the fan air inlets/
outlets are unobstructed.
3. If, after 30 minutes of ventilation,
the alarm is still on in the display,
contact the technical support.
The power supply to the system is
unsuitable.
Check that the supply voltage
specied on the rear panel of the
device matches the voltage of the
power supply.
The speed control or the detection
system is faulty.
1. Switch o the device.
2. Contact the technical support.
Motor error
If one of these faults persists, contact the technical team.
8 CLEANING AND DISINFECTION
8.1 Recommendations
For safety reasons, and to avoid damaging the equipment, the following
recommendations must be observed:
The exterior of the equipment can be cleaned with a sponge or cloth that
has been moistened with water, 70% alcohol or a disinfectant, e.g. Anios
Surfa’Safe.
Do not spray liquids directly onto the device, especially the
electrical connectors and the openings of the casing (vents and
air inlet)
Unplug the equipment before cleaning.
Do not use a scraper sponge: risk of damage to the device.
Do not use an aerial disinfection process.
Do not use caustic soda or acetone: the device will be
irreversibly damaged.
Immediately remove any liquid from the equipment with a dry
cloth.
8.2 Disinfection protocol
Should a tube burst during operation, for example, the parts likely to be
contaminated by infectious agents must be disinfected with a suitable
disinfectant.
The user shall assume full responsibility for their choice of disinfection
process.
The parts likely to be contaminated can, for example, be cleaned using a
paper towel soaked in a 6 °Cl diluted solution of bleach.
If another disinfection process has to be implemented, contact the technical
support service beforehand in order to conrm that the procedure is
compatible with the equipment.
9 MAINTENANCE AND SERVICING
9.1 Repair
The equipment must undergo a cleaning and disinfection protocol before
being shipped for a repair.
The equipment must be shipped with the return slip clearly specifying the
procedure used, the people involved as well as the date of the cleaning or
disinfection process (see appendix 1).
If there is no duly completed return slip, the equipment cannot be processed
by the Bertin Technologies’After-Sales Service.
Replacing the power cord:
Similarly, when replacing the power cord, it is important
to use a cord with exactly the same characteristics (…
VAC-… A).
The user must be aware of the signicant risk in the
event of non-compliance with this rule.

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Wear part Reference Replacement frequency
Blocking plate 2 ml 1 year or when damaged
Vacuum seal 6 months or when damaged
Containment seal 1 year or when damaged
Fuse When it has blown
O-centre bearing 5 months or when damaged
Anti-rotation kit 1 year or when damaged
Anti-vibration mounts If the suspended part hits the xed
part repeatedly during the cycles
Encountered problem Possible cause(s) Remedial measures
There is no power at the mains
socket.
1. Check the mains voltage.
2. Check that the voltage supplied by
the mains matches that of the device.
3. Check the connection of the device
to the mains.
The fuse is defective. Replace the fuse.
The ventilation system is defective. 1. Switch o the device.
2. Contact the technical support.
There is no power at the mains
socket.
1. Check the mains voltage.
2. Check that the voltage supplied
by the mains matches that of the
device.
3. Check the connection of the
device to the mains.
The fuse is defective. Replace the fuse
The display system is defective. 1. Switch o the device.
2. Contact the technical support.
The fuse holder displays a rated
voltage of 220V while the power
supply is 110V
1. Unplug the device from the mains
2. Remove the fuse holder from its
compartment
3. Remove the seat from one of the
fuses
4. Reverse the position to the 110V
side
5. Replace the fuse holder by
snapping it into its compartment
The top was screwed on incorrectly or
the tube is defective.
The tube used is not a Precellys®
tube
If the product contained in the
tube is hazardous or potentially
hazardous, perform the appropriate
disinfection procedure.
The operating limits were not
respected
For safety reasons, the blocking
plate stays locked in position by the
vacuum system.
Switch the device back on in order to
remove the blocking plate.
The fan is not turning.
The screen does not turn on.
A tube is no longer sealed.
Power cut
9.2 Problems encountered 9.3 Replacing wear parts
This paragraph species the maintenance that users must perform on a
regular basis to ensure that the Precellys® 24 Touch works properly and that
the tubes are maintained during the homogenisation phase:
The levels of the voltages in the device are hazardous.
In order to guarantee the safety of the user, including
during the cleaning and disinfection phases, the
containment seal must not be damaged (puncture,
tear, etc.)
DO NOT tilt the device: the Precellys® 24 Touch must
always be resting on its four feet. If not, the internal
components can get damaged or the plastic casing
will break.

PRECELLYSEVOLUTION
9.3.1 Replacing the vacuum seal
The vacuum seal on the tube holder wears out
during operation. It is recommended to change
it when the «Pressure error» alarm appears
permanently or recurrently. As a preventive
measure, this seal should be replaced at least
once every 6 months.
9.3.2 Replacing the containment seal
The containment seal should be changed at least once a year. The tube
holder does not have to be dismantled when replacing it.
1. Place the inner groove of the containment
seal over the metal ange.
2. Place the outer groove of the containment
seal on the housing. The containment seal
should be changed at least once a year. The
metal btube holderet does not have to be
removed in order to do this procedure
9.3.3 Replacing the fuse
Mettre l’appareil hors tension et débrancher le cordon
secteur avant d’eectuer cette opération.
Switch o the appliance and unplug the power cord
before carrying out this operation.
Remove the fuse holder by pinching the retaining clips.
Fuse
9.3.4 Replacing the anti-rotation tubes
The anti-rotation tubes should be changed at least once a year. The tube
holder does not have to be dismantled when replacing them.
Switch o the appliance and unplug the power cord
before carrying out this operation.

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PRECELLYSEVOLUTION
PRECELLYS®24 Touch MANUEL UTILISATEUR
Rotate the tube holder.
Disconnect the rst anti-rotation tube by pulling on the assembly from
one side to the other.
Install the new anti-rotation tube by connecting it on one side and then
on the other.
Do the same with the other anti-rotation tube.
11 APPENDICES:
11.1 Electrical diagram
9.4 Support
If any information is not present in this manual, contact your local
distributor.
For the latest information on our services, you can consult the www.
bertin-technologies.com page.
You can contact the Bertin Instruments team at the following address:
[e-mail] .
10 ELIMINATION
The cleaning and disinfection procedure is mandatory before disposing
of the equipment in order to protect people and the environment.
The equipment, its spare parts and its consumables are to be sorted and
recycled in accordance with the directive on waste electrical and electro-
nic equipment (WEEE) 2012/19/EU.
Bertin Technologies is responsible for processing WEEE
for its products sold in France (via RECYLUM). For
other countries, the importer is responsible for waste
processing.

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11.1 Precellys® returns
Should you wish to return a Precellys, contact your local distributor.
11.2.1 Preparing the Precellys® 24 Touch
11.2.2 Positioning the original packaging
1. Open the lid and place the
black foam padding inside.
2. Close the lid.
1. Place the lower black foam pad on the cardboard
drawer.
2. Place the Precellys® 24 Touch in its space, while
ensuring that the housing and feet are fully inserted
into the foam.
3. Cover the Precellys® 24 Touch with the upper
black foam pad.
4. Place the assembly right in the bottom of the
cardboard box.
Do not hold the device by the
lid when putting it in its box. It
must be held using either the
extraction handles provided
or by holding the equipment
from underneath at the notches
provided on the side of the
casing. There are also notches
provided in the lower protective
foam pad.
Given its mass, the device should preferably be
handled by two operators.
11.2.3 Packing
1. Close the box with strong packing tape when ready.
2. Place the box on a pallet and secure it with strapping.
Handle the device with care as signicant shocks can
damage the equipment.

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PRECELLYS®24 Touch MANUEL UTILISATEUR
NOTESNOTES

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PRECELLYS®24 Touch MANUEL UTILISATEUR
NOTESNOTES

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