Biotage V-10 Touch User guide

Biotage®V-10 Touch
Installation and Safety

Biotage®V-10 Touch Installation and Safety | © Biotage 2019
Contents
CONTENTS
1Installation
1 Download Biotage®V- Touch User Documentation
1 Software License Agreement
1 Site Requirements
2 Move the System
3 Connections
4 Connect an External Computer Running
Biotage®V- Touch Control Centre
5 Connect a Liquid Handler (Gilson GX-271)
5 Technical Specification
6Safety
6 Intended Use
6 Education, Training, and Competence
6 Warranty and Liability
6 Service
6 Labels
6 Safety Requirements
8 WEEE Compliance Statement
8 Safety in Other Languages
9General Information
9 Accessories and Spare Parts
9 Manufacturer
9 Contact Us
Biotage®V-10 Touch
Installation and Safety


Installation
Site Requirements
Before the system is installed by an authorized Biotage service
engineer, the installation site should be prepared as follows:
Fume Hood/
Ventilation
System
The system must be placed in a well-ventilated
fume hood or an equivalent enclosure.
Weight and
Dimensions
The total weight of the package including the
system is 75 kg (165 lbs). Use suitable lifting
equipment when moving the package.
The fume hood or bench must be able to support
the weight of the system, i.e. 50 kg (110 lbs).
The dimensions of the system are (W x D x H):
400 x 480 x 540 mm (15.7" x 18.9" x 21.3") or
480 x 550 x 540 mm (18.9" x 21.7" x 21.3") when
equipped with a carousel.
The ventilation panels on the top and back are
necessary to ensure adequate cooling of the system
and must not be blocked.
Leave a minimum distance of 100 mm (4") between
the rear of the system and any solid objects. The
system requires this clearance to ensure adequate
cooling of the system.
Operating
Temperature
18°C to 32°C
Humidity 20% to 90% RH (non-condensing)
Electrical
Supply
220 to 240 V~, 50/60 Hz, 2100 VA
Connect only to a properly grounded outlet.
External
Vacuum Pump
Optional. Connect using a KF-16 vacuum flange.
External
Computer
Computer with Windows 7, 8, 8.1, or 10.
Only required when using V-10 Touch Control Centre.
External Fire
Protection
External fire protection should be installed
according to local regulations for equipment
operating unattended.
Warning
» The system must be unpacked and installed by an authorized
Biotage service engineer.
» Follow regional safety practices when handling and moving
shipping boxes and containers, and when moving the system.
» Observe general and specific safety regulations for the use of
the system and its accessories at all times in order to reduce
the risk of personal injury, fire, and explosion; see “Safety
Requirements” on page 6.
Note: We recommend that the boxes and packing materials are
kept by the customer in case the system needs to be returned
for service or moved to another location.
Download Biotage®V- Touch
User Documentation
The following user documentation can be downloaded at
www.biotage.com:
» Biotage®V- Touch Installation and
Safety, P/N 414661 (this document)
» Biotage®V- Touch User Manual, P/N 414662
» Biotage®V- Touch Safety Translations, P/N 414663
» Biotage®V- Touch Quick Guide, P/N UI336
If you have problems downloading the user documentation,
please contact your local Biotage representative. See contact
information on the back of this document or visit our website
www.biotage.com.
Software License Agreement
Biotage Sweden AB licenses the Biotage®V- Touch software to
you only upon the acceptance of all of the terms and conditions
in the software license agreement supplied with the system.
By using the software, you consent to be bound by and are
becoming a party to that agreement.
Installation

Biotage®V-10 Touch Installation and Safety | © Biotage 2019
Installation
Move the System
Warning
» Before moving the system, please read and observe the safety
requirements in “Safety Requirements” on page 6.
If you need to move the system within the laboratory or between
laboratories in the same building, follow the instructions below.
If you need to ship the system, please contact Biotage®1-Point
Support™for instructions.
Note: If the mains voltage is not the same at the new location,
contact Biotage 1-Point Support.
1. Prepare the new site according to the site requirements on
page 1.
2. If necessary, defrost the system. See instructions in the
“Maintenance” chapter of the user manual (P/N 414662).
3. If the system is equipped with a built-in sample pump, clean
the tubing and empty the system of all liquid by priming it
with air:
a. Clean the tubing as described in the “Maintenance”
chapter of the user manual (P/N 414662).
b. Remove the system solvent bottle and insert the solvent
inlet tube into a clean, empty bottle.
c. If using a system without a liquid handler:
i. Place the sample inlet tube in a clean and empty
waste container.
ii. Select Maintenance from the menu bar on the touch
screen.
iii. Press Prime.
iv. Press the Prime Volume field and enter 45 mL.
v. Press Prime and then Tube and Waste Container in
Position to start the prime operation.
d. If using a system with a liquid handler:
i. In the Controller application, select Settings... from
the File menu. The Settings dialog opens.
ii. Set the Needle Drain Volume to 40 mL and the Needle
Wash Volume to 5 mL.
iii. Click .
e. When the prime operation is completed, remove and
empty the waste container.
4. Turn off (O) the system. The mains switch is located on the
left side of the system; see A in Figure 2.
5. Unplug the power cord from the power outlet.
6. If an external vacuum pump, a liquid handler and/or an
external computer is/are connected to the system, turn
it/them off and disconnect it/them from the system.
7. Clean the touch screen with a soft and clean cloth. The cloth
can be lightly dampened with isopropanol or ethanol.
8. Clean the exterior of the system with a soft and clean cloth.
The cloth can be lightly dampened with ethanol or similar.
9. The system weighs 50 kg (110 lbs). Carefully lift the system
and place it on a trolley that can support the weight of the
system. A minimum of two persons are required when lifting
the system. Note that the system is front heavy. Lift slowly.
Note: When the system is equipped with a carousel, do not
lift holding the carousel unit.
10. Move the equipment to the new location.
11. Carefully lift the system (see step 9) and place it in a
well-ventilated fume hood or on a bench. Place the system
so that the mains switch is easy to access.
Note: The ventilation panels on the top and back are necessary
to ensure adequate cooling of the system and must not be
blocked. Leave a minimum distance of 100 mm (4 inches)
between the rear of the system and any solid objects.
12. Ensure that a flexible, solvent resistant tube with an inner
diameter of 6 mm (¼ inch) is connected to the condenser
drain connector (see A in Figure 3), and inserted into a
collection vessel of a suitable size. Ensure that the tube
cannot become immersed in the waste liquid.
13. If applicable, ensure that a flexible, solvent resistant tube
with an inner diameter of 6 mm (¼ inch) is connected to the
pump exhaust connector (see B in Figure 3) and directed
into a proper ventilation system.
14. If the system is equipped with a built-in sample pump,
ensure that all connections are properly connected and
tightened. See “Fluid Connections (Optional)” on page 4.
15. If using an external vacuum pump, connect it to the system
using a KF-16 vacuum flange (see Figure 4) and ensure that
the fumes are directed into a proper ventilation system.
16. If applicable, connect a liquid handler to the serial port
(see G in Figure 2) and/or an external computer running V-
Touch Control Centre to the Ethernet port (see D in Figure 2).
17. Connect the system to a properly grounded (earthed) power
outlet with the correct mains voltage and frequency.
18. Ensure that the power cord and any cables, hoses, and
tubing connected to the system cannot come in contact with
chemicals. Corrosives and solvents can degrade the cord/
cable insulation and dissolve the hoses and tubing. There is
a risk of electric shock, fire, and/or equipment damage.
19. Wait one hour for the cooling media to stabilize before
turning on (I) the system.
20. If the system is equipped with a carousel, the Alert –
Initializing Carousel dialog opens. Keep your hands away
from the carousel and press Initialize Carousel.
21. When the Confirm Collection Vessel dialog is displayed,
confirm that you have performed step 12 above and start
the drain operation and condenser start-up by pressing
Tube and Vessel in Position.


Installation
22. When the condenser has been drained and the condenser
start-up period is completed, the text “System Ready” is
displayed in the top right corner of the touch screen. If
necessary, empty the waste container.
If the system has been shut down for a while, it can take
up to 20 minutes for the condenser to reach its target
temperature.
Figure 1.A system with an external vacuum pump connected.
Connections
Power Supply and Communication Connections
Warning
» Do not connect the system to an electrical supply that is not in
accordance with the system’s electrical specifications; see the
rating plate located on the left side of the system.
» The system must be electrically grounded (earthed). Use
only a power cord supplied by Biotage. The plug should only
be connected to a grounded outlet as per local and national
regulations. Keep the mains plug easily accessible in case the
system needs to be disconnected quickly from mains power.
» Use only exact replacement fuses supplied by Biotage. Incorrect
fuses create a potential fire hazard.
The power inlet, mains switch, fuses, and communication
connections are located on the left side of the system; see Figure 2.
Figure 2
A
BB
CD
EF
G
.The connections on the left side of the system. A = mains switch,
B= fuse holders, C = power inlet, D = Control Centre communication port,
E = carousel communication port, F = carousel power connection, and
G = Gilson communication port.
Condenser Drain Connector
Ensure that a flexible, solvent resistant tube with an inner
diameter of 6 mm (¼ inch) is connected to the condenser drain
connector (see A in Figure 3) and inserted into a collection
vessel of a suitable size. Ensure that the tube cannot become
immersed in the waste liquid.
Figure 3
A
B
.The condenser drain connector (A) and the pump exhaust
connector for the internal vacuum pump (B).
Pump Exhaust Connector
We recommend that a flexible, solvent resistant tube with an
inner diameter of 6 mm (¼ inch) is connected to the pump
exhaust connector (see B in Figure 3) and directed into a proper
ventilation system.
External Vacuum Pump (Optional)
Warning
» If using an external vacuum pump, ensure that the fumes are
directed into a proper ventilation system.
An external vacuum pump is recommended to reach the low
pressure needed for three of the predefined methods (Very High
Boil, High Boil, and Mixed Vol & HBP).
Connect the external vacuum pump to the system using a KF-16
vacuum flange; see Figure 4. Ensure that the fumes are directed
into a proper ventilation system.
Note: If the external vacuum pump is enabled in the system
settings and in the evaporation method, ensure that the
external vacuum pump is connected and turned on before
starting the evaporation run.
Figure 4.The connection for the external vacuum pump is located on the
right side of the system.

Biotage®V-10 Touch Installation and Safety | © Biotage 2019
Installation
Fluid Connections (Optional)
If the system is equipped with a built-in sample pump, all fluid
connections should be connected as shown below. Note that
the sample inlet tube (blue in Figure 5) can be connected to
either an external flask or a liquid handler.
Figure 5.The fluid connections (not to scale).
The following ports are available on the pump manifold:
Port Connect
LOOP (x2) The sample loop (red in Figure 5).
SAMPLE
ROBOT
The sample inlet tube (blue in Figure 5). The system
is shipped with a sample inlet tube that must be used
when aspirating sample solution from an external flask.
If using a liquid handler, use the sample inlet tube that
is supplied with the liquid handler.
Note: During a prime operation that is started from
the touch screen, the sample inlet tube must be placed
in a suitable waste container.
VIAL The vial tubing that is connected to the sample inlet
connection (green in Figure 5). The green vial tube
must stick out 2 to 3 mm from the upper vial holder or
the upper vial adapter; see Figure 6.
SS The system solvent inlet tube (orange in Figure 5).
Figure 6
A B
.The tube must stick out 2 to 3 mm from the upper vial holder (A)
or the upper vial adapter (B).
Connect an External Computer Running
Biotage®V- Touch Control Centre
V- Touch Control Centre is installed on an external computer
and adds the capabilities of integrating the V- Touch system
with a liquid handler as well as running the carousel with different
methods for different carousel positions. The software can also
be used for exporting log files from the V- Touch system.
Install Biotage®V-10 Touch Control Centre
V- Touch Control Centre runs on Windows 7, 8, 8.1, and 10.
Double-click the V- Touch Control Centre installer file and
follow the instructions that appear in the installation wizard.
To get the installer file, please contact Biotage 1-Point Support.
See contact information on the back of this document or visit
our website www.biotage.com.
V- Touch Control Centre requires that Microsoft .NET
Framework 4 is installed. If missing, it is installed automatically
by the installation program.
During the installation, two shortcuts are placed on the desktop,
Editor and Controller, and the folder C:\Program Files (x86)\
Biotage\Biotage V- Touch Control Centre is created. The folder
contains the executable files, user file, racks, and workspaces.
Connect the Computer to the System
1. In the Windows start menu, type network and sharing center
and press the Enter key to launch.
2. Click Change adapter settings in the left column.
3. Select the Ethernet network adapter to be used to connect to
the system and click Properties.
4. Select Internet Protocol Version (TCP/IPv4) and click
Properties. See Figure 7.
5. Select Use the following IP address: and set the IP address
to 192.168.1.54 and the Subnet mask to 255.255.255.0. See
Figure 7.
6. Click OK.
Figure 7.Setting up the IP address for the external computer.


Installation
7. Connect an Ethernet cable to the Ethernet port on the system
(see D in Figure 2) and to an Ethernet port on the computer.
8. Test the connection by opening the Controller application.
If the connection fails, you are notified and the software is
opened in offline mode. Resolve the network problem and
retry to connect by selecting Settings... from the File menu
and then clicking Test Connection... in the Settings dialog.
Connect a Liquid Handler (Gilson)
Warning
» The liquid handler must be unpacked and installed by an
authorized Biotage service engineer.
Before running an evaporation job using a liquid handler, ensure
that the liquid handler is correctly set up.
1. Ensure that the liquid handler has the Z-arm positioned at
175 mm; see Figure 8A. To adjust the height, loosen the two
screws holding the arm in position using a 2.5 mm Allen
wrench (see Figure 8B).
Figure 8
AB
.Ensure that the Z-arm is positioned at 175 mm (A). Adjust by
loosening the two screws holding the arm in position (B).
2. Ensure that the needle is flush with the bottom of the needle
guide (see Figure 9A) and not bent. To adjust the needle
height, loosen the needle holder screw (see Figure 9B).
Figure 9.
AB
Ensure that the needle is flush with the bottom of the needle
guide (A). Adjust by loosening the needle holder screw (B).
Technical Specification
Solvent
Compatibility
Boiling points from 30°C to 160°C (to 205°C
when using an external vacuum pump)
The system is not suitable for solutions
containing HCl (hydrochloric acid), NaOH
(sodium hydroxide), HNO3(nitric acid), H2SO4
(sulphuric acid), H2O2(hydrogen peroxide)
or NaClO (sodium hypochlorite) at any
concentration
Heating 20°C to 70°C
Rotational Speed 3000 to 8000 rpm
Condenser Refrigerated condenser temperature: -25°C
Automated and manual defrost and draining
Vacuum Pressure control method: Variable speed and
level
Internal vacuum pump: 2 mbar
Optional: An external vacuum pump can be
connected using a KF-16 vacuum flange
Vial Sizes 30 mL scintillation vial
20 mL scintillation vial
16 mL vial
8 mL vial
4 mL vial (3 variants)
Sample Pump
(optional)
10 mL syringe pump, 1 to 100 mL/min
Sample loop: 15 mL
Redissolve precision: 1% CV for 2 to 12 mL and
2% CV for 0.5 mL
Redissolve accuracy: 0.5% for 2 to 12 mL and
1% for 0.5 mL
Ambient
Temperature
Operating: 18°C to 32°C
Storage and transportation: -25°C to 60°C
Humidity 20% to 90% RH (non-condensing)
Electrical
Supply
220 to 240 V~, 50/60 Hz
Fuses F10A at the power inlet (2 required)
Maximum Power
Consumed
2100 VA
Weight 50 kg (110 lbs)
Dimensions
(W X D X H)
400 x 480 x 540 mm (15.7" x 18.9" x 21.3")
or 480 x 550 x 540 mm (18.9" x 21.7" x 21.3")
when equipped with a carousel.
Leave a minimum distance of 100 mm (4 inches)
between the rear of the system and any solid
objects. The system requires this clearance to
ensure adequate cooling of the system.
Max Sound Level 75 dB(A)
Interface 7" touch screen
Accessories Automation Upgrade
Solvent Manager Upgrade
Gilson Liquid Handler GX-271
Certifications CE marked and CB and NRTL certified

Biotage®V-10 Touch Installation and Safety | © Biotage 2019
Safety
Safety
Intended Use
Biotage®V- Touch from Biotage is intended solely for
concentrating samples for applications in organic and inorganic
chemistry. The system has to be operated in a laboratory
environment by trained professionals. All operations must be
performed:
» According to the user documentation
delivered with the system.
» According to instructions available at www.biotage.com.
» According to instructions provided through
dialogs appearing on the screen.
» According to instructions given by the
technical support staff from Biotage.
» Within limits set by the system’s technical specification.
Failure to follow those instructions and operate within the limits
set by the technical specification may result in personal injury
and/or equipment damage.
Education, Training, and Competence
It is your responsibility to provide all applicable health and
safety regulations to your personnel. You must also ensure that
all personnel involved in the operation and maintenance of the
system fulfill the following criteria:
» Have the necessary education, training, and competence
required for the intended use of the system.
» Observe general and specific safety regulations for the
use of the system and its accessories at all times in order
to reduce the risk of personal injury, fire, and explosion.
Warranty and Liability
See the “Biotage Terms & Conditions of Sale” document at
www.biotage.com.
Service
All service must be performed by an authorized Biotage service
engineer. Before handing over the system for service, it should
be emptied of all liquid and cleaned from harmful residues.
It is the responsibility of the customer to inform Biotage 1-Point
Support representatives if the system has been used with
hazardous biological, radioactive, or toxic samples and/or
solvents, prior to any service being performed. When returning
equipment to Biotage, this should be done in accordance with
the material return procedures supplied separately by Biotage.
Only genuine Biotage spare parts must be used in the system.
Labels
Labels used on the system:
In accordance with all the essential requirements of
all applicable European product directives; see the
Declaration of Conformity.
In accordance with both U.S. and Canadian safety
standards; see the Declaration of Conformity.
Subject to the Waste Electrical and Electronic
Equipment (WEEE) Directive; see “WEEE Compliance
Statement” on page 8.
Manufacturer.
Hot surface. The heater nozzle and spin motor may get
warm during operation.
Consult accompanying user documentation.
Safety Requirements
You must observe all safety requirements when installing and
operating the system. Failure to install or use the system in
a manner specified by Biotage may result in personal injury
and/or equipment damage.
If the system has been damaged or does not function properly,
shut it down immediately and contact Biotage 1-Point Support
(www.biotage.com).
Installation
» The system must be unpacked and installed by an
authorized Biotage service engineer. Prepare the
installation site as described on page 1.
» Follow regional safety practices when handling and moving
shipping boxes and containers, and when moving the system.
» The total weight of the package including the
system is 75 kg (165 lbs). Use suitable lifting
equipment when moving the package.
» The system weighs 50 kg (110 lbs). It must be
lifted by a minimum of two persons. Note that
the system is front heavy. Lift slowly.
Note: When the system is equipped with a carousel, do not
lift holding the carousel unit.
» Do not place any equipment or bottles
on top of or above the system.


Safety
» Do not connect the system to an electrical supply that is not
in accordance with the system’s electrical specifications;
see the rating plate located on the left side of the system.
» The system must be electrically grounded (earthed).
Use only a power cord supplied by Biotage. The plug
should only be connected to a grounded outlet as
per local and national regulations. Keep the mains
plug easily accessible in case the system needs to
be disconnected quickly from mains power.
» Ensure that the power cord and any cables, hoses,
and tubing connected to the system cannot come
in contact with chemicals. Corrosives and solvents
can degrade the cord/cable insulation and dissolve
the hoses and tubing. There is a risk of electric
shock, fire, and/or equipment damage.
» The system must be placed in a well-ventilated fume
hood or an equivalent enclosure. Follow local and
national safety regulations for installing a system
inside a fume hood and the safety regulations
supplied by the fume hood manufacturer.
» If using an external vacuum pump, ensure that the
fumes are directed into a proper ventilation system.
» External fire protection should be installed according to
local regulations for equipment operating unattended.
» Do not block any of the ventilation panels. These
are located on the top and back and are necessary
to ensure adequate cooling of the system.
Operation
» Use the system only for its intended purpose, as described
in the user documentation delivered with the system and
user documentation available at www.biotage.com.
» To avoid leakage, ensure that all connections are properly
connected and tightened before operating the system.*
» To avoid damaging the system, use care to ensure that all
solvents used with the system are free of particulates.*
» Never operate the system when damaged
or with the plastic guard removed.
» Keep your hands away from the vial loading arm
and carousel (if used) while the vial is being loaded
or unloaded and during carousel initialization.
» The heater nozzle and spin motor may get
warm during operation. Avoid contact.
» Do not exceed a vial’s maximum fill volume; see the
“Vials” section of the user manual (P/N 414662).
Chemical and Biological Safety
» Check regularly for leaks and spills. Always
handle leakage immediately.
» Always place the solvent bottle and waste
container on the side of the system.*
» The system operates using electricity, which can
introduce additional hazards with certain solvents
if not properly connected, vented, or set up with
recommended manufacturer approved settings.
» Follow all generally-accepted lab safety procedures
and applicable laws and regulations.
» Always follow local and national safety
regulations related to storage, handling and
disposal of chemicals, samples and waste.
» Read and understand the safety data sheet (SDS)
provided by the chemical manufacturer before
storing, handling, working with, or disposing
of any chemical or hazardous substance.
» Personnel working with or near the system must wear
protective clothing, safety gear, and eye protection that
comply with local and national safety regulations.
Maintenance and Troubleshooting
» Follow all maintenance instructions in the “Maintenance”
chapter of the user manual (P/N 414662).
» There are no user serviceable parts inside the system.
Covers and safety shields may only be removed by an
authorized Biotage service engineer. Potential electrical
hazard exists due to high voltage circuits inside the system.
» The power cord should be inspected periodically
and replaced if damaged or altered. Use only
a power cord supplied by Biotage.
» The system uses double pole fusing. Use only
exact replacement fuses supplied by Biotage.
Incorrect fuses create a potential fire hazard.
» If an inlet or exhaust fan at the top and the back
of the system stops working, shut down the
system and contact Biotage 1-Point Support.
» The heater nozzle and spin motor may
get warm during operation.
» The condenser may contain harmful residues. Defrost
the condenser before removing the condenser pot.
» Use caution when finger-tightening fittings to
prevent stripped threads or crushed ferrules.*
* Only for systems equipped with a built-in sample pump.

Biotage®V-10 Touch Installation and Safety | © Biotage 2019
Safety
WEEE Compliance Statement
Valid for customers in EU countries
We are committed to being a good corporate
citizen. As part of that commitment, we strive
to maintain an environmentally conscious
manufacturing operation. The European Union (EU)
has enacted a directive on product recycling
(Waste Electrical and Electronic Equipment, WEEE).
Products falling under the scope of the WEEE Directive are
identified with a crossed over “wheelie bin” symbol on the
product label, as indicated to the left. To forward a product
for recycling or proper disposal, use an authorized collection
system or return it to Biotage Sweden AB. Before forwarding
a product for recycling or disposal, it should be emptied of all
liquid and cleaned from harmful residues. When returning a
product to Biotage, this should be done in accordance with the
material return procedures supplied separately by Biotage.
Safety in Other Languages
Translated versions of the safety chapter can be downloaded at
www.biotage.com. If you have problems downloading the safety
translations (P/N 414663), please contact your local Biotage
representative. See contact information on the back of this
document or visit our website www.biotage.com.


General Information
General Information
Accessories and Spare Parts
Only Biotage and Biotage approved accessories and spare parts
must be used in the system. To order accessories and spare
parts, see contact information on the back of this document or
visit our website www.biotage.com.
Manufacturer
Biotage, Salem NH, USA for
Biotage Sweden AB
Contact Us
Biotage Sweden AB
Box 8
SE-751 03 Uppsala
SWEDEN
Visiting address: Vimpelgatan 5
Phone: [phone]
Fax: [phone]
E-mail: [e-mail]
Website: www.biotage.com
Please contact your local Biotage representative. See contact
information on the back of this document or visit our website
www.biotage.com.

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