Bruker SamplePro hr-MAS User manual

Version
Innovation with Integrity
SamplePro hr-MAS
002
NMR Spectroscopy
SamplePro hrMAS
Service Manual

Copyright©by Bruker Corporation GmbH
All rights reserved. No part of this publication may be
reproduced, stored in a retrieval system, or transmitted, in
any form, or by any means without the prior consent of the
publisher. Product names used are trademarks or
registered trademarks of their respective holders.
This manual was written by
Stanley J. Niles and Gilbert Cyppel
© August 19, 2011: Bruker Biospin GmbH
Rheinstetten, Germany
P/N: Z31946
DWG-Nr.: Z4D11366A
For further technical assistance on the SamplePro hr-Mas
unit, please do not hesitate to contact your nearest
BRUKER dealer or contact us directly at:
BRUKER BioSpin GMBH
am Silberstreifen
D-76287 Rheinstetten
Germany
Phone:+ 49 721 5161 0
FAX:+ 49 721 5171 01
E-mail:[e-mail]
Internet:www.bruker.com

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Table of Contents
Contents
1 About ............................................................................................................11
1.1 This Manual............................................................................................................ 11
1.2 Policy Statement .................................................................................................... 11
1.3 Symbols and Conventions...................................................................................... 11
2 Introduction..................................................................................................13
2.1 Concept .................................................................................................................. 13
2.2 Before you begin .................................................................................................... 13
2.3 Minimum Qualifications for Service Personnel....................................................... 14
2.4 The Bruker Service................................................................................................. 14
2.5 Transport to Manufacturer...................................................................................... 14
3 Safety Information.......................................................................................15
3.1 Intended Use .......................................................................................................... 15
3.2 Owner‘s Responsibility ........................................................................................... 15
3.3 Personnel Requirements........................................................................................ 16
3.3.1 Qualifications.......................................................................................................... 16
3.3.2 Unauthorized Persons............................................................................................ 17
3.3.3 Instruction............................................................................................................... 17
3.4 Personal Protective Equipment .............................................................................. 17
3.5 Basic Dangers ........................................................................................................ 18
3.6 Environmental Protection ....................................................................................... 21
3.7 Signage .................................................................................................................. 22
3.7.1 Warning Signs ........................................................................................................ 22
4 Tool List........................................................................................................23
4.1 Required for Exchange Unit ................................................................................... 23
4.2 Required for SamplePro hr-MAS............................................................................ 23
4.3 Required tools that can be ordered from Sias........................................................ 24
4.4 Optional .................................................................................................................. 24
4.5 Figures ................................................................................................................... 24
5 Principles of Operation...............................................................................27
5.1 Main Components .................................................................................................. 27
5.2 Description of the Robotic System ......................................................................... 30
5.2.1 Safety Door ............................................................................................................ 31
5.2.2 The Frame.............................................................................................................. 32
5.2.2.1 Y-Arm ..................................................................................................................... 32
5.2.3 Object Detector ...................................................................................................... 33
5.2.4 Barcode Reader ..................................................................................................... 33
5.2.5 Pickup Adapter ....................................................................................................... 33
5.2.6 Control Unit for the Cooling Device ........................................................................ 33

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5.2.7 Control Wheel......................................................................................................... 33
5.2.8 Safety Door Lock .................................................................................................... 33
5.2.9 The Cooling Rack................................................................................................... 34
5.2.10 The Deck Tray ........................................................................................................ 34
5.2.11 Other Components ................................................................................................. 34
5.2.11.1 HR-MAS Software .................................................................................................. 34
5.2.11.2 The SamplePro LED Status Light........................................................................... 35
5.3 The SamplePro Exchange Unit .............................................................................. 36
5.3.1 Exchange Unit Back Panel..................................................................................... 36
5.3.2 Exchange Unit Internal Components...................................................................... 38
5.3.2.1 Mechanics .............................................................................................................. 40
5.3.2.2 Pneumatics............................................................................................................. 41
5.4 Description of the MAS Unit - COM Mode.............................................................. 41
5.5 Description of the hr-MAS Probe............................................................................ 41
6 Installation....................................................................................................43
6.1 Before You Begin ................................................................................................... 43
6.1.1 Site Planning .......................................................................................................... 43
6.1.1.1 Gas Support ........................................................................................................... 43
6.2 Installation Procedure Overview............................................................................. 44
6.3 Robot System Installation....................................................................................... 44
6.3.1 Receiving the Product ............................................................................................ 44
6.3.1.1 Unpacking............................................................................................................... 45
6.3.2 Hardware Installation.............................................................................................. 45
6.3.3 Installing the Optional Cooling Rack....................................................................... 47
6.3.4 Barcode Identification Option for the Rotor Container............................................ 48
6.3.5 Connecting the Power Cable.................................................................................. 49
6.4 MAS Unit Configuration .......................................................................................... 49
6.5 Exchange Unit Installation ...................................................................................... 50
6.5.1 Mechanical Installation ........................................................................................... 50
6.5.2 Electronic Installation.............................................................................................. 52
6.5.3 Transfer Hose Installation....................................................................................... 55
6.5.4 Pneumatics Installation........................................................................................... 58
6.5.4.1 Transfer Pressure Setup ........................................................................................ 59
6.6 Software Installation (Optional) .............................................................................. 61
6.6.1 CAN Driver for the Robot and Exchange Unit ........................................................ 61
6.6.1.1 Installing the Robot CAN Interface Driver............................................................... 62
6.6.1.2 Installing the Exchange Unit CAN Interface Driver................................................. 66
6.6.1.3 Communication Settings......................................................................................... 68
6.6.2 SamplePro hr-MAS Application Software............................................................... 68
7 System Configuration .................................................................................71
7.1 Overview................................................................................................................. 71

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7.2 Configuring the Device Settings ............................................................................. 72
7.2.1 Initial Settings ......................................................................................................... 73
7.2.1.1 Main Settings.......................................................................................................... 74
7.2.1.2 Robot Settings........................................................................................................ 74
7.2.1.3 Robot Teaching ...................................................................................................... 75
7.2.1.4 Exchange Unit Settings .......................................................................................... 75
7.2.1.5 Device Test ............................................................................................................ 77
7.2.1.6 Standard Device User ............................................................................................ 77
7.3 Notification Service................................................................................................. 77
7.4 Alarm Settings ........................................................................................................ 78
7.5 Maintenance Tasks ................................................................................................ 78
7.6 Statistics ................................................................................................................. 78
7.7 Backing up the Settings Configuration ................................................................... 78
7.8 Importing, Exporting and Restoring Device Settings.............................................. 79
7.9 The Robot Device Manager ................................................................................... 79
7.10 TopSpin Configuration............................................................................................ 80
8 Verification and Calibration........................................................................83
8.1 Pre-test Checklist ................................................................................................... 83
8.2 Robotic System Teaching ...................................................................................... 83
8.2.1 Teaching the Pickup Adapter ................................................................................. 84
8.2.2 Teaching the Rotor Detection Position................................................................... 85
8.2.3 Teaching the Barcode Reader Position.................................................................. 87
8.2.4 Teaching the Rotor Container Detection Position .................................................. 88
8.2.5 Teaching the Security Eject Position...................................................................... 89
8.3 Robot System Device Test..................................................................................... 91
8.3.1 Performing the Individual Test Steps ..................................................................... 92
8.3.1.1 Step 1: Select the Rotor Position ........................................................................... 92
8.3.1.2 Step 2: Open Cover of Rotor Container ................................................................. 92
8.3.1.3 Step 3: Detect Rotor............................................................................................... 92
8.3.1.4 Step 4: Goto Selected Rotor Position..................................................................... 92
8.3.1.5 Step 5: Move Rotor from Rotor Container to Exchange Unit ................................. 93
8.3.1.6 Step 6: Move Rotor from Exchange Unit to MAS Probe ........................................ 93
8.3.1.7 Step 7: Start and Stop Spinning ............................................................................. 93
8.3.1.8 Step 8: Move Rotor from MAS Probe to Exchange Unit ........................................ 93
8.3.1.9 Step 9: Move Rotor from Exchange Unit to Rotor Container ................................. 94
8.3.1.10 Step 10: Close Cover of Rotor Container............................................................... 94
8.3.2 Actions Test in a Test Loop.................................................................................... 94
8.4 Exchange Unit Service Dialog................................................................................ 95
8.4.1 Valve Control.......................................................................................................... 96
8.4.2 Sensor Control ....................................................................................................... 96
8.4.3 MAS Proxy Functions............................................................................................. 96
8.4.4 Barcode Reader Control......................................................................................... 97
9 Service - Minor Corrective Actions............................................................99

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9.1 Introduction............................................................................................................. 99
9.2 Robotic System Maintenance................................................................................. 99
9.2.1 Securing Screws................................................................................................... 100
9.2.1.1 Securing Gear Screws.......................................................................................... 100
9.2.2 Mains Fuse (Input)................................................................................................ 100
9.2.3 Output Fuses........................................................................................................ 101
9.2.4 CAN-Bus and Extensions (loop)........................................................................... 102
9.2.5 Deck ..................................................................................................................... 102
9.2.6 Arm Housing......................................................................................................... 103
9.2.6.1 Arm Cover ............................................................................................................ 104
9.2.6.2 Side and Front Cover Plate .................................................................................. 105
9.2.6.3 Rear Cover Plate .................................................................................................. 107
9.2.7 X-Axis Components.............................................................................................. 108
9.2.7.1 MCB X-Motor Board ............................................................................................. 108
9.2.7.2 X-Gear .................................................................................................................. 109
9.2.7.3 X-Motor................................................................................................................. 111
9.2.8 CAN Connector Board.......................................................................................... 115
9.2.9 Device X-Rail........................................................................................................ 116
9.2.9.1 X-Belt.................................................................................................................... 116
9.2.9.2 X-Spacers............................................................................................................. 116
9.2.9.3 Caterpillar Drive Chain ......................................................................................... 116
9.2.9.4 CAN-Bus Wiring ................................................................................................... 117
9.2.9.5 Safety Door........................................................................................................... 118
9.2.10 Y-Axis Components.............................................................................................. 119
9.2.10.1 YZ-Board .............................................................................................................. 119
9.2.10.2 Y-Motor Assembly (spring-loaded Y-motor support) ............................................ 121
9.2.10.3 Y-Motor (spring-loaded Y-motor support)............................................................. 123
9.2.10.4 Spring-Loaded Y-Motor Support........................................................................... 124
9.2.10.5 YZ-Module ............................................................................................................ 126
9.2.11 Z-Axis Components .............................................................................................. 126
9.2.11.1 YZ-Board .............................................................................................................. 126
9.2.11.2 Z-Motor Assembly ................................................................................................ 127
9.2.11.3 Z-Motor .................................................................................................................129
9.2.12 Arm Alignment Check........................................................................................... 131
9.2.13 Pickup Adapter ..................................................................................................... 132
9.2.14 Object Detector..................................................................................................... 134
9.2.15 Barcode Reader ................................................................................................... 136
9.2.16 Cooling Rack ........................................................................................................ 137
9.2.17 Nitrogen Flow Sensor ........................................................................................... 139
9.2.18 Checking the Nitrogen Flow Sensor Connection and Settings............................. 142
9.2.19 Door Lock Actor.................................................................................................... 144
9.2.20 Door Open Sensor................................................................................................ 145
9.2.21 Status Light Board ................................................................................................ 145
9.3 Exchange Unit Malfunctions ................................................................................. 147
9.3.1 Light Barrier .......................................................................................................... 147

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10 Service - Major Corrective Actions..........................................................149
10.1 Replacing the Power Supply Unit......................................................................... 150
10.2 Adjusting the X-Belt Tension ................................................................................ 154
10.2.1 Mechanical Principle of the X-Drive ..................................................................... 154
10.2.2 Checking the Tension of the X-Belt...................................................................... 155
10.2.3 Adjusting the Tension of the X-Belt ...................................................................... 157
10.3 Exchanging Boards and Motors ........................................................................... 158
10.3.1 Introduction........................................................................................................... 158
10.3.1.1 Exchanging Controller Boards.............................................................................. 158
10.3.2 Replacing the X-Board ......................................................................................... 158
10.3.3 Replacing the X-Motor.......................................................................................... 159
10.3.4 Replacing the YZ-Module..................................................................................... 163
10.3.5 Replacing the YZ-Board ....................................................................................... 164
10.3.6 Replacing the Y-Motor (with fixed support) .......................................................... 165
10.3.7 Replacing the Y-Motor (with spring-loaded support) ............................................ 166
10.3.8 Replacing the Z-Motor.......................................................................................... 167
10.3.8.1 Z-Motor Check...................................................................................................... 168
10.3.8.2 Coil Resistance Check ......................................................................................... 170
10.4 Arm Alignment...................................................................................................... 171
10.4.1 Arm Adjustment.................................................................................................... 172
10.4.2 Arm Assembly and Testing .................................................................................. 173
11 Troubleshooting ........................................................................................175
11.1 Error Reporting Checklist ..................................................................................... 175
11.2 History Files and Log Files ................................................................................... 175
11.2.1 History files........................................................................................................... 176
11.2.2 Robot System Sub-device Log Files .................................................................... 176
11.3 Error Information Dialogs ..................................................................................... 177
11.3.1 Initialization Warning Dialog ................................................................................. 177
11.3.2 Standard Error Dialog at Run Time ...................................................................... 178
11.3.3 Robot System Sub-device Error Window ............................................................. 179
11.3.4 Exchange Unit Sub-device Errors ........................................................................ 182
11.3.5 Special Error Handling ......................................................................................... 185
11.4 Start Problems Due to Virus Scanner Setup ........................................................ 185
11.5 Firmware .............................................................................................................. 185
11.5.1 Validating Firmware Parameters .......................................................................... 186
11.5.1.1 Correct Configuration (display)............................................................................. 186
11.5.1.2 Incorrect Configuration (Display).......................................................................... 188
11.5.2 Firmware and Parameters.................................................................................... 189
11.5.2.1 Firmware Download ............................................................................................. 189
11.5.2.2 Firmware Parameter Setup .................................................................................. 189
11.5.3 Troubleshooting Corrupted Firmware Configuration ............................................ 189
11.5.3.1 Configuration Conflict after Module Identification................................................. 190

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11.5.4 Procedure to Restore a Correct FW Parameter Configuration............................. 193
11.5.4.1 Software Procedure.............................................................................................. 193
11.5.4.2 Emergency Procedure.......................................................................................... 194
11.5.5 Communication Error While Reading X-Util FW Parameters ............................... 194
11.6 Y- and Z-Motor and Controller Board ................................................................... 196
11.6.1 Motor does not Initialize........................................................................................ 196
11.6.2 Motor Moves in Negative Direction with Positive Values...................................... 197
11.6.3 Motor Check ......................................................................................................... 197
11.6.4 Z-motor shakes when sensing for liquid ............................................................... 198
11.6.5 Controller Board Check ........................................................................................ 199
11.6.5.1 Controller Board Troubleshooting......................................................................... 199
11.7 USB / CAN-Bus .................................................................................................... 200
11.7.1 Communication Problems Linked to USB Devices............................................... 200
11.7.2 Mixup of USB CAN Adapters................................................................................ 202
12 Spare Parts.................................................................................................205
12.1 Robotic System Parts........................................................................................... 205
12.2 Exchange Unit Spare Parts .................................................................................. 213
13 Electrical and Pneumatic Data.................................................................215
13.1 Robotic System PCB Pinout................................................................................. 215
13.1.1 MCB X-Motor Board V2.11................................................................................... 215
13.1.2 MCB BB1 V2.0 ..................................................................................................... 216
13.1.3 MCB BB2 V2.0 ..................................................................................................... 216
13.1.4 Object Detector HZ16890_C ................................................................................ 217
13.2 Exchange Unit Pneumatic Data............................................................................ 218
13.3 Exchange Unit Electrical Data .............................................................................. 221
14 Preventive Maintenance............................................................................227
15 Transport, Packaging and Storage..........................................................229
15.1 Symbols on the Packaging ................................................................................... 229
15.2 Inspection at Delivery ........................................................................................... 231
15.3 Packaging............................................................................................................. 232
15.4 Storage ................................................................................................................. 232
15.5 Returning the Robotic System.............................................................................. 232
15.5.1 Robot and Part Shipping Precautions .................................................................. 233
15.5.2 Preparing the Robot System for Transport........................................................... 233
15.5.2.1 Dismounting.......................................................................................................... 233
15.5.3 Packing the Robot System for Transport.............................................................. 233
15.5.3.1 Packing the arm.................................................................................................... 233
15.5.3.2 Packing the Tool Arm ........................................................................................... 234
15.5.3.3 Packing the Deck Tray and Frame ....................................................................... 234

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16 Cleaning and Disposal..............................................................................237
16.1 Cleaning ............................................................................................................... 237
16.2 Environmental Protection ..................................................................................... 238
16.3 Decommissioning, Recycling and Disposal of the Robotic System ..................... 239
17 Technical Data ...........................................................................................241
17.1 General................................................................................................................. 241
17.2 Electrical............................................................................................................... 242
17.3 Operating Conditions............................................................................................ 243
17.4 Rating Plate System............................................................................................. 243
17.5 Rating Plate Robot ............................................................................................... 244
17.6 Rating Plate Exchange Unit ................................................................................. 244
18 Specifications ............................................................................................245
18.1 Motion Speed ....................................................................................................... 245
18.2 Electrical and Communication.............................................................................. 245
18.3 Safety and Security .............................................................................................. 246
18.4 Physical Properties............................................................................................... 246
18.4.1 Precision............................................................................................................... 246
18.5 Computer and Software Requirements ................................................................ 247
18.5.1 Recommended Options........................................................................................ 247
18.5.2 Material Chemical Resistance.............................................................................. 248
19 Contact .......................................................................................................249
A Appendix ....................................................................................................251
A.1 Warning Signs ...................................................................................................... 251
A.2 Figures ................................................................................................................. 253
A.3 Tables................................................................................................................... 259
A.4 Glossary ............................................................................................................... 261
A.5 Index..................................................................................................................... 263

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11
Z31946_00_02
1 About
1.1 This Manual
This manual is intended to be a reference guide for Bruker certified service engineers
who have already completed a Bruker designated training course. It provides detailed
information about the installation, maintenance and service and overall use of the Bruker
device.
The figures shown in this manual are designed to be general and informative and may
not represent the specific Bruker model, component or software/firmware version you
are working with. Options and accessories may or may not be illustrated in each figure.
Read carefully all relevant chapters before working on the device!
This manual describes parts and procedures relevant to the device version it is delivered
with. For older hardware, please refer to the manual supplied at the time.
1.2 Policy Statement
It is the policy of Bruker to improve products as new techniques and components
become available. Bruker reserves the right to change specifications at any time.
Every effort has been made to avoid errors in text and figure presentation in this publica-
tion. In order to produce useful and appropriate documentation, we welcome your com-
ments on this publication. Support engineers are advised to regularly check with Bruker
for updated information.
Bruker is committed to providing customers with inventive, high quality products and ser-
vices that are environmentally sound.
1.3 Symbols and Conventions
Safety instructions in this manual are marked with symbols. The safety instructions are
introduced using indicative words which express the extent of the hazard.
In order to avoid accidents, personal injury or damage to property, always observe
safety instructions and proceed with care.
DANGER
This combination of symbol and signal word indicates an immediately hazardous sit-
uation which could result in death or serious injury unless avoided.

12 Z31946_00_02
About
iThis symbol highlights useful tips and recommendations as well as information designed
to ensure efficient and smooth operation.
WARNING
This combination of symbol and signal word indicates a potentially hazardous situa-
tion which could result in death or serious injury unless avoided.
CAUTION
This combination of symbol and signal word indicates a possibly hazardous situation
which could result in minor or slight injury unless avoided.
NOTICE
This combination of symbol and signal word indicates a possibly hazardous situation
which could result in damage to property or the environment unless avoided.

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Z31946_00_02
2 Introduction
The SamplePro hr-MAS is a sample changer that was developed for high throughput,
high resolution, magic angle spinning (hr-MAS) applications, such as the measurement
of biological samples.
The new sample changer is part of a Bruker NMR system for standard NMR MAS appli-
cations and is used to transfer prepared MAS samples to and from Bruker NMR devices
to ensure they stay in continuous operation.
2.1 Concept
The sample changer consists of a laboratory robot (SamplePro) and a transfer system
connecting the laboratory robot to the probe inside the NMR magnet.
The sample changer provides a Bruker standard interface, through which the changer
can be controlled from TopSpin and IconNMR software.
Refer to the user manual Z31914 for a complete description of the design and function of
SamplePro hr-MAS.
2.2 Before you begin
This service manual contains information and safety information that are necessary for
the installation and service of the SamplePro hr-MAS.
All maintenance and repairs are to be accomplished using the information in this man-
ual. At the same time references over general maintenance and care from the User
Manual are also to be followed.
Consider all safety references!
Information for ordering spare parts is available in the spare parts section for from the
Bruker Service Center (see "Contact" on page 249).

14 Z31946_00_02
Introduction
2.3 Minimum Qualifications for Service Personnel
2.4 The Bruker Service
See "Contact" on page 249.
2.5 Transport to Manufacturer
When the SamplePro hr-Mas must be returned to the manufacturer for a major repair,
use the original packaging for transportation.
See "Exchange Unit Malfunctions" on page 147.
Include a good description of the problem.
Type of Task Personnel Training and Experience
Transportation No special requirements. No special.
Installation Bruker certified personnel only. Technically skilled, with a good
knowledge of the application field.
Routine Use Appropriately certified and
experienced personnel, famil-
iar with use of computers and
automation in general
Laboratory technicians or equiva-
lent. Training is usually done in-
house. Familiar with Microsoft®
Windows® environment.
Daily Maintenance
Setup and optimization
of program
Bruker certified personnel only. Experienced laboratory techni-
cian. High degree of knowledge of
the relevant application field.
Preventive Maintenance Bruker certified personnel only. Technically skilled with a basic
understanding of the application.
Servicing Bruker certified personnel only. Background and experience in
electronics/mechanics with com-
puter knowledge.
Table 2.1 Overview Installation and Operation Requirements for Personnel

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Z31946_00_02
3 Safety Information
This section provides an overview of all the main safety aspects involved in ensuring
optimal personnel protection and safe and smooth operation.
Non-compliance with the action guidelines and safety instructions contained in this man-
ual may result in serious hazards.
3.1 Intended Use
The SamplePro hr-MAS sample changer has been designed and constructed to transfer
prepared MAS samples to and from Bruker NMR devices to ensure it stays in continuous
operation.
The sample changer must only be used for keeping MAS samples in a specially
designed well plate, inserting them into the NMR spectroscopy magnet and ejecting
them after measurement back into the well plate.
Since samples may undergo degradation at room temperature, the SamplePro hr-MAS
device provides cooling to -16°C and +4°C.
Intended use also includes compliance with all specifications in this manual.
Any use which exceeds or differs from the intended use shall be considered improper
use.
No claims of any kind for damage will be entertained if such claims result from improper
use.
3.2 Owner‘s Responsibility
Owner
The term owners refers to the person who themselves operates the unit for trade or
commercial purposes, or who surrenders the unit to a third party for use/application, and
who bears the legal product liability for protecting the user, the personnel or third parties
during the operation.
Owner‘s Obligations
The unit is used in the industrial sector. The owner of the unit must therefore comply with
statutory occupational safety requirements.
In addition to the safety instructions in this manual, the safety, accident prevention and
environmental protection regulations governing the operating area of the unit must be
observed.
In this regard, the following requirement should be particularly observed:

16 Z31946_00_02
Safety Information
• The owner must obtain information about the applicable occupational safety regula-
tions, and - in the context of a risk assessment - must determine any additional dan-
gers resulting from the specific working conditions at the usage location of the unit.
The owner must then implement this information in a set of operating instructions
governing operation of the appliance.
• During the complete operating time of the unit, the owner must assess whether the
operating instructions issued comply with the current status of regulations, and must
update the operating instructions if necessary.
• The owner must clearly lay down and specify responsibilities with respect to installa-
tion, operation, troubleshooting, maintenance and cleaning.
• The owner must ensure that all personnel dealing with the unit have read and
understood this manual. In addition, the owner must provide personnel with training
and hazards information at regular intervals.
• The owner must provide the personnel with the necessary protective equipment.
Furthermore, the owner is responsible for ensuring that the unit is always in technically
faultless condition. Therefore, the following applies:
• The owner must ensure that the maintenance intervals described in this manual are
observed.
• The owner must ensure that all safety devices are regularly checked to ensure full
functionality and completeness.
3.3 Personnel Requirements
3.3.1 Qualifications
This manual specifies the personnel qualifications required for the different areas of
work, listed below:
Qualified Personnel
Qualified personnel are able to carry out assigned work and to recognize and prevent
possible dangers self-reliantly due to their professional training, knowledge and experi-
ence as well as profound knowledge of applicable regulations.
WARNING
Danger of injury if personnel are insufficiently qualified.
If unqualified personnel perform work on the unit or are in the unit‘s danger zone,
hazards may arise which can cause serious injury and substantial damage to prop-
erty.
Therefore, all work must be carried out by appropriately qualified personnel.
Unqualified personnel must be kept away from the danger zones.

17
Z31946_00_02
Safety Information
The workforce must only consist of persons who can be expected to carry out their work
reliably. Persons with impaired reactions due to, for example, the consumption of drugs,
alcohol, or medication are prohibited.
When selecting personnel, the age-related and occupation-related regulations governing
the usage location must be observed.
3.3.2 Unauthorized Persons
3.3.3 Instruction
The personnel must receive regular instruction from the owner. The instruction should be
documented to facilitate improved verification.
3.4 Personal Protective Equipment
Personal protective equipment is used to protect the personnel from dangers which
could affect their safety or health while working.
The personnel must wear personal protective equipment, as prescribed in the laborato-
ries standard operating procedures, while carrying out the different operations at and
with the unit.
WARNING
Risk to life for unauthorized persons due to hazards in the danger and
working areas.
Unauthorized persons who do not meet the requirements described here will not be
familiar with the dangers in the working zone. Therefore, unauthorized persons face
the risk of serious injury or death.
Unauthorized persons must be kept away from the danger and working zone.
If in doubt, address the persons in question and ask them to leave the danger and
working zone.
Cease work while unauthorized persons are in the danger and working zone.

18 Z31946_00_02
Safety Information
3.5 Basic Dangers
NOTICE
Material damage hazard from overflow of cryogens.
Material damage may result from the overflow of cryogens.
Turn off the unit during magnet servicing.
Cover the unit with a protective cover to avoid contact with cold gases.
Be sure to use sufficient transfer line and Teflon evacuation hose for nitrogen and
helium refills based on recommendations in the magnet manual.
After refilling cryogens some parts of the magnet may be icy. Be sure to remove
the ice to avoid its melting onto the unit.
CAUTION
Accident hazard from contact with hot or cold surfaces on the unit.
Contact with the hot or cold surfaces of the unit may result in serious burns.
Do not touch unit parts of cooled or heated units.
Do not use damaged units.
After removing any part of the unit, allow it to cool or thaw before coming in con-
tact.
WARNING
Accident hazard from asphyxiation.
A break in a tube or hose may result in the uncontrolled exit of nitrogen into the labo-
ratory.
An oxygen warning device must be present in the laboratory if the device is oper-
ated with nitrogen.
Proper air ventilation must be planned and implemented in the laboratory.

19
Z31946_00_02
Safety Information
CAUTION
Accident hazard from breaking or spilled samples.
Samples may break or be spilled due to improper adjustment or cap loss. This may
result in personal injury or equipment contamination.
Follow the mounting, installation and adjustment instructions in the manual.
Confirm the correct installation at the customer site through use of acceptance
protocol.
Standard operating procedures for sample preparation and usage must be imple-
mented.
During installation and maintenance use only rotors with dummy samples.
Remove all MAS rotors (also from the magnet) before the installation and mainte-
nance!
WARNING
Biological, chemical hazard.
Infection, contamination, or other health endangerment as a result of contact with
biological or chemical substances, e.g. from broken samples.
Clean the unit before maintenance work and/or returning to Bruker for repair.
Prepare a list of materials in which the unit came into contact with or measured.
A signed confirmation of correctly carrying out cleaning/disinfection is required
from the customer. Without this confirmation the parts delivered for repair will be
rejected and returned to the customer.

20 Z31946_00_02
Safety Information
iNote: Reference measurements should be made at regular intervals to help detect pos-
sible vibration and/or electromagnetic interference.
DANGER
Accident and/or material damage hazard from sample breakage.
Contact with hazardous substances contained in sample rotors that break may result
in a life threatening situation or material damage. The contents of the sample rotors
are the responsibility of the laboratory supervisor. The laboratory supervisor is
responsible for:
Defining disinfectant and cleaning procedures.
Establishing and enforcing the use of protective clothing (gloves, eye protection,
mask etc.).
Preparing laboratory instructions for handling this type of accident.
Preparing an emergency plan.
Enforcing standard sample handling procedures, e.g. removing all samples from
the rotor container and using sample rotors with dummy contents before mainte-
nance work etc.
Training laboratory personnel.
NOTICE
Material damage hazard due to improper restart.
Device deadlock may occur as a result of restarting the unit when an equipment fail-
ure has occurred.
When an error has occurred, do not try to restart the unit until the cause of the
error has been corrected.
Only trained personnel should carry out maintenance work.