FujiFilm VisualSonics Vevo F2 User manual

Vevo F2 Imaging
System
User Manual
PartNumber: 53188-04
Revision: 1.0
Last Updated: May 2022

2
Legal Notices
North American Headquarters 
FUJIFILMVisualSonicsInc.
3080YongeStreet,Suite6100,Box66
Toronto,Ontario,Canada
M4N3N1
T.1-416-484-5000
F.1-416-484-5001
Toll free1-866-416-4636
European Headquarters 
FUJIFILMVisualSonics
JoopGeesinkweg140
1114ABAmsterdam,
TheNetherlands
T.[phone]
Toll free[phone]
Manufacturer 
FUJIFILMSonoSite,Inc.
2191930thDr.SE
Bothell,WA,98021
USA
T.1-425-951-1200
F.1-425-951-1201
Toll free1-888-482-9449
Website:www.visualsonics.com 
VisualSonics,theVisualSonicslogo,Vevo,VevoMicroMarkerandEKVareregisteredandunregistered
trademarksofFUJIFILMSonoSite,Inc.invariousjurisdictions.FUJIFILMisaregisteredtrademarkof
FUJIFILMCorporationinvariousjurisdictions.
Patents:6,851,392;6,984,284;7,052,460;7,133,713;7,230,368;7,255,678;7,426,904;7,434,542;
7,740,585;7,750,536;7,798,963;7,808,156;7,830,069;7,901,358;8,078,256;8,275,449;8,310,133;
8,316,518;8,317,714;8,343,289;8,708,909;8,823,246;8,827,907;8,847,467;8,945,014;9,173,047;
9,184,369;9,520,119;9,555,443;9,445,787;9,474,498;9,935,254;9,997,696;D541,942.
Noticeofnon-liability:FUJIFILMVisualSonics,Inc.isprovidingtheinformationinthisdocumenttoyouasis
withallfaults.FUJIFILMVisualSonics,Inc.makesnowarrantiesofanykind(whetherexpress,impliedor
statutory)withrespecttotheinformationcontainedherein.FUJIFILMVisualSonics,Inc.assumesnoliability
fordamages(whetherdirectorindirect),causedbyerrorsoromissions,orresultingfromtheuseofthis
documentortheinformationcontainedinthisdocumentorresultingfromtheapplicationoruseofthe
productorservicedescribedherein.FUJIFILMVisualSonics,Inc.reservestherighttomakechangestoany
informationhereinwithoutfurthernotice.
Copyright©2022FUJIFILMVisualSonics,Inc.AllRightsReserved.FUJIFILMVisualSonics,Inc.isa
subsidiaryofFUJIFILMSonoSite,Inc.

3
Table of Contents
Introduction 16
DifferencesBetweentheVevoF2andVevoF2LT 16
DocumentConventions 17
SystemOverview 18
VevoF2ImagingSystem 18
ImageDisplay 18
ControlPanel 19
BasicTouchscreenActions 20
OnscreenKeyboard 22
SystemStartup 23
ToTurnOntheLaserCart 24
LoggingOnfortheFirstTime 25
ToCreatetheAdministratorAccount 27
QuickStartGuide-B-Mode 28
BeforeYouBegin 28
ToAcquire,AnalyzeandExportaB-ModeImage 28
QuickStartGuide-PA-Mode 30
BeforeYouBegin 30
ToAcquire,AnalyzeandExportaPA-ModeImage 30
QuickStartGuide-VADAMode 32
BeforeYouBegin 32
ToAcquire,Review,SaveandExportVADAModeData 32

4
Session Tasks 34
LoggingIn 34
InterfaceOverview 35
ImageDisplay 36
ControlPanelInterface(Scanning) 38
ControlPanelInterface(Review) 41
CommonTasks 43
ChangeScanningModes 43
ChangeTransducersorApplications 43
AdjustImage 44
FreezeImage/ResumeScanning 44
InsertMarkup 44
ChangeControlsonControlPanel 44
SaveanImageorClip 44
SelectingaTransducerorApplication 45
PhysiologySettings 47
Annotations 56
Measurements 61
CustomizingControls 91
SavingImages 98
VevoVoice 102
ToUseVevoVoice 102
SupportedMicrophones 103
ToEnableVevoVoice 103

5
VevoVoiceCommands 104
AdjustVevoVoiceVolume 106
LoggingOut 107
Modes 108
B-Mode 109
B-ModeImageDisplayInterface 109
B-ModeControlPanelInterface 109
B-ModeControls 114
B-ModeNeedleGuideforInjections 119
B-ModeGenericMeasurements 121
M-ModeandAM-Mode 122
M-ModeandAM-ModeImageDisplay 122
M-ModeandAM-ModeControlPanelInterface 123
M-ModeandAM-ModeAcquisitionWorkflow 125
M-ModeandAM-ModeControls 126
M-ModeandAM-ModeGenericMeasurements 129
PWDopplerandPWTissueDopplerMode 131
PWDopplerandPWTissueDopplerImageDisplay 131
PWDopplerandPWTissueDopplerControlPanelInterface 132
PWDopplerModeImageAcquisitionWorkflow 135
PWTissueDopplerModeImageAcquisitionWorkflow 137
PWDopplerandPWTissueDopplerControls 139
PWDopplerandPWTissueDopplerGenericMeasurements 146
ColorandPowerDopplerMode 147

6
ColorandPowerDopplerImageDisplay 147
ColorDopplerandPowerDopplerControlPanelInterface 149
ColorDopplerModeImageAcquisitionWorkflow 150
PowerDopplerModeImageAcquisitionWorkflow 151
ColorDopplerandPowerDopplerControls 152
ColorDopplerandPowerDopplerGenericMeasurements 157
PA-Mode 158
BeforeYouBegin 158
StagingandAcquisitionStates 158
PA-ModeImageDisplayInterface 158
PA-ModeControlPanelInterface 162
PA-ModeImageAcquisitionWorkflow 165
ListofPASub-Modes 168
PASub-ModeSettings 168
PA-ModeControls 176
PAGuide 183
VevoSpectralUnmixing 186
PA-ModeGenericMeasurements 189
LaserCalibration 190
LaserIssueNotification 192
NonlinearContrastMode 193
ContrastAgentTechnology 193
NonlinearContrastModeImageDisplay 193
NonlinearContrastModeControlPanelInterface 195

7
NonlinearContrastModeAcquisitionWorkflow 196
NonlinearContrastModeControls 197
ECGandRespirationGating 201
NonlinearContrastModeGenericMeasurements 202
3DMode 203
3DModeHardwareSetup 204
3DModeImageAcquisitionWorkflow 204
3DModeImageDisplay 206
3DModeControlPanel 207
Workingwith3DModeImages 209
3DModeControls 212
3DModeGenericMeasurements 215
EKVMode 216
EKVModeImageDisplay 216
EKVModeImageAcquisitionWorkflow 217
EKVModeImageReview 218
4D-Mode 220
4D-ModeHardwareSetup 220
4D-ModeAcquisitionWorkflow 220
4D-ModeImageDisplay 222
4D-ModeControlPanel 223
Workingwith4D-ModeImages 225
4D-ModeImagePost-Processing 227
4D-ModeControls 228

8
4D-ModeGenericMeasurements 230
DigitalRF 231
AcquireRFData 231
RFImageDisplayInterface 233
ReviewanRFImage 234
ExportRFData 234
VADAMode 236
SignalCustomizationinVADAMode 236
HardwareLimitations 237
TransducerThermalManagement 237
VADAWorkflow 238
VADAImageDisplayInterface 239
VADAControlPanelInterface 240
VADAModeControls 240
VADAClipSettings 243
TransducerSettingsPanel 244
SpeedofSound 245
Voltage 249
LiveImage 251
VADAConfigurationPanel 251
Settings 283
TransducerPreview 284
Review 317

9
Study Browser 320
FilteringtheListofStudiesintheStudyBrowser 320
WorkingwithStudies 321
SearchingintheStudyBrowser 321
AdjusttheStudyBrowserInterface 322
CreatingaStudy 323
EditingaStudy 325
DeletingaStudy 326
LockingandUnlockingaStudy 326
WorkingwithSeries 326
CreatingaNewSeries 327
EditingaSeries 329
MovingaSeries 329
ClosingaSeries 329
Re-openaSeries 330
DeletingaSeries 330
ViewCurrentSeries 331
WorkingwithImages 332
ToOpenanImage 332
ToNameanImageFromtheStudyBrowser 332
ModifyingaStoredImage 332
StoringanImage 332
DeletinganImage 333
ExportImages 334

10
ExportingImagesfromtheStudyBrowser 334
ExportingStudiestoVevoLAB 337
ExportingFromtheModeWindow 337
System Settings 339
Navigation 339
Administration 339
UserManagement 341
PasswordRules 349
BackupandRestore 351
Network 355
Date&Time 359
Security 361
Reset 363
Applications&Presets 365
HowApplicationsandPresetsWork 365
OpentheApplications&PresetsMenu 365
Navigation 366
ManageApplications 367
ManagePresets 371
Export 375
ToDisplaytheExportPage 375
ExportOptions 376
ToDefineExportOptions 376
General 378

11
ToSelecttheGeneralTab 378
InterfaceOverview 379
Measurements&Annotations 380
DisplayOptions 381
CalculationOptions 381
EditAnnotations 381
Network(User-level) 382
InterfaceOverview 383
Photoacoustics 383
ToDisplaythePhotoacousticsPage 383
InterfaceOverview 384
ManageSingleWavelengthBookmarks 385
SpectralCurves 385
Sound&Display 388
ToDisplaytheSound&DisplayPage 388
InterfaceOverview 389
SystemInformation 389
ToDisplaytheSystemInformationPage 389
InterfaceOverview 390
SystemLogs 390
ToDisplaytheSystemLogsPage 391
Interface 391
ToExportLogFiles 392
ToDeleteLogFiles 392

12
UserAccount 392
ToDisplaytheUserAccountPage 393
Interface 393
VADA 394
Navigation 394
Import,ExportandDeletePulseSequences 395
VevoVoice 396
OpentheVevoVoiceTab 396
InterfaceOverview 397
VoiceOptions 397
VoiceTraining 398
Components 401
VevoF2ImagingSystem 401
ImageDisplay 401
StandHead 403
Speakers 404
CastorsandHandles 404
PowerModule 404
SystemConnectors 406
DataStorageandNetwork 410
VevoLAZR-XLaserCartExternalFeatures 410
PowerPlug 411
LaserPorts 411
LaserIndicators 412

13
LaserConnections 414
EmergencyStopButton 417
CastorsandHandles 417
Transducers 418
CouplingGels 418
TransducerCompatibilityChart 418
StoringTransducers 419
TransducerandGelHolder 421
TransducerApplications 421
LAZR-XTransducers 421
Accessories 427
VevoIntegratedRailSystem 428
VevoAnimalMonitoringSystem 428
VevoLAZRTight 429
VevoPHANTOMImagingChamber 433
VevoLAB 434
VevoInfusionPump 435
Maintenance 440
MovingtheSystemorLaser 440
Disposal 440
SystemUpgrade 441
BeforeYouBegin 441
ToInstallaSystemUpgrade 441
LicenseUpdate 443

14
ToExportYourMachineID 443
ToUpdateYourSystemLicense 444
CleaningandDisinfecting 444
BeforeYouBegin 445
ListofCompatibleCleanersandDisinfectants 446
CleaningandDisinfectingtheVevoF2ImagingSystem 447
CleaningandDisinfectingTransducers 448
CleaningandDisinfectingtheLaser 449
CleaningandDisinfectingAccessories 450
Reference 452
ImagingGuides 452
VevoF2ImagingSystemSpecifications 452
EnvironmentalSpecifications 452
PhysicalDimensions 452
ElectricalSpecifications 453
VevoLAZR-XLaserCartSpecifications 455
LabelInformation 457
SystemLabels 457
VevoLAZR-XLaserCartLabels 459
SafetyInformation 461
VevoF2ImagingSystemSafety 461
LaserSafety 464
ComplianceInformation 468

15
VevoF2ImagingSystem 468
VevoLAZR-Xlasercart 469
EndUserLicenseAgreement(EULA) 470
ContactandLegalInformation 477
FUJIFILMVisualSonics 477
DocumentInformation 477
Support 477
SoftwareLicenses 478
DICOMToolKit(DCMTK) 478
Scintilla 489
VisualizationToolkit(VTK) 489
zlib 490
Keterex,Inc. 492
Troubleshooting 493
VevoF2Troubleshooting 493
LaserTroubleshooting 493
LAZRTightTroubleshooting 494
StudyBrowserTroubleshooting 494
B-ModeTroubleshooting 494
PA-ModeTroubleshooting 495
PhysiologicalDataTroubleshooting 495
StartRemoteHelpSession 497

Vevo F2 Imaging System User Manual
Introduction 16
Introduction
The Vevo F2 logo
TheVevoF2ImagingSystemisahigh-resolution,real-timeultrasoundsystemintendedfordiagnostic
imagingandfluidflowanalysisonsmallanimalsinlaboratoryenvironments.Availablefeaturesdependon
yoursystemconfiguration,transducer,andoperationalmode.
TheVevoF2LTImagingSystemisasimplifiedversionofthestandardVevoF2ImagingSystem.Itis
designedforbasicin vivoresearchusingsmallandlargeanimalmodels.
TheVevoLAZR-Xlasercartisaclass4laseradd-onthatisusedwiththeVevoF2forphotoacoustic
imaging.
WARNING: THISEQUIPMENTISNOTAPPROVEDFORUSEONHUMANS.
TheVevoF2ImagingSystemandVevoLAZR-Xlasercarthavebeendesigned
andtestedforuseonlaboratoryresearchanimalsonly.
Thisequipmentmustnotbeusedonanylivinghumanbeing.
Thisguideiswrittenforuserswhoarefamiliarwithultrasound,anddoesnotprovidetraininginsonography.
BeforeusingtheVevoF2ImagingSystem,in-depthtrainingfromanexperienceduser,suchasaFUJIFILM
VisualSonicsApplicationsSpecialist,isrecommended.
Differences Between the Vevo F2 and Vevo F2 LT
The Vevo F2 LT logo
Inthismanual,somesectionsrefertofeaturesthatareavailableontheVevoF2,butnottheVevoF2LT.
WhenusingaVevoF2LT,thesesectionscanbeignored.
TheVevoF2LTdiffersfromtheVevoF2inthefollowingways:
lTheVevoF2LTfeaturesthefollowingimagingmodes.Allothermodesarenotavailable:
oB-Mode
oM-Mode
oColorDopplerMode

Vevo F2 Imaging System User Manual
Introduction 17
oPWDopplerMode
lWhileboththeVevoF2andVevoF2LTusethesamesetoftransducers,onlycardiacapplications
areavailableontheVevoF2LT.
lDatafromtheVevoF2LTcanbeanalyzedinVevoLAB,butisnotcompatiblewithVevoVascor
VevoStrain.
lSeveralfeaturesarenotavailableontheVevoF2LT,sotheircorrespondinginterfaceoptionsare
notavailable.Allfeaturedifferencesarelistedinthetablebelow:
Feature Difference Corresponding Interface Difference
RF-Modeisnot
available.
IntheSystem Settings >Export menu,theexportoptionforRFDataisnot
available.OnlytheRAW optionisavailable.
Thefootpedalisnot
supported.
IntheSystem Settings >General menu,theFoot Pedal Configuration
sectionisnotavailable.
Displayoptionscannot
beconfigured.
IntheSystem Settings >General menu,theDisplay Options sectionisnot
available.
PA-Modeisnot
available. IntheSystem Settings menu,thePhotoacoustics tabisnotavailable.
VADAModeisnot
available. IntheSystem Settings menu,theVADA tabisnotavailable.
VevoVoiceisnot
available. IntheSystem Settings menu,theVevo Voice tabisnotavailable.
FrameMarkersarenot
available. TheAdd Frame Marker buttonisnotavailable.
Document Conventions
Noteboxesappearthroughoutthisdocumenttohighlightkeypiecesofinformation.
WARNING: Warnsofissuesthatmayresultininjuryordeath.
Caution: Warnsofissuesthatmaycausedatalossorequipmentdamage.
Note: Highlightsimportantinformation.

Vevo F2 Imaging System User Manual
Introduction 18
System Overview
VevoF2ImagingSystem
TheVevoF2ImagingSystemconsistsofthefollowingmajorcomponents:
lThetopscreenistheimagedisplay,whichdisplaysimagingdata.
lThebottomscreenisthetouchscreencontrolpanel,whichservesasthecontrolsurfaceforthe
system.
lThebaseofthesystemhousestheelectronicsthatmakeuptheVevoF2ImagingSystem.
The Vevo F2 Imaging System
Formoreinformationaboutthesystemanditscomponents,refertoComponentsonpage401.
ImageDisplay
TheimagedisplayisthetopmonitoroftheVevoF2,andprimarilydisplaysimagingdata.

Vevo F2 Imaging System User Manual
Introduction 19
The image display when the system is in B-Mode
Whiletheimagedisplayvariesslightlydependingonthecurrentimagingmode,italwaysdisplaysseveral
categoriesofdata:
lImaginginformation:Containsinformationsuchasthenameofthestudy,series,imagename,
imagingmode,transducerused,aswellasvariousimagingparameters.
lImage:Thecurrentimage.Thiscanbealiveimageorapreviouslysavedimage.
lAnimalphysiology:Displaystheanimal'svitalsigns.
Note: Formoreinformationabouttheimagedisplaylayout,refertoImageDisplay
onpage36.
ControlPanel
ThecontrolpanelisatouchscreenthatdisplaystheVevoF2userinterface.

Vevo F2 Imaging System User Manual
Introduction 20
The control panel
Thecontrolpanelcontainsthefollowingfeatures:
lAtopbarthatnavigatesbetweenmenuswithintheVevoF2software.
lAworkingareathatcontainsimageadjustmentcontrolsforthecurrentlyselectedimagingmode.
lAcollectionofcontrolbuttonsthatcarryoutoneofthefollowingfunctions:
oSelectsanimagingmode
oOpensfeaturesofthecurrentlyselectedimagingmode
oAdjuststhecurrentimage
oExecutesafunctiononthecurrentimage
lCustomizablesidebarsthatareusedtoholdthemostcommonlyusedcontrolbuttons.
Note: Formoreinformationaboutthecontrolpanelinterface,refertoControl
PanelInterface(Scanning)onpage38andControlPanelInterface(Review)on
page41.
BasicTouchscreenActions
ThecontrolpanelisatouchscreenthatservesasthemaincontrolinterfacefortheVevoF2.Thisscreen
supportsthesameactionsasthoseoftypicaltouchscreendevices.
Thefollowingtablelistscommontouchscreenactions,andalistofVevoF2functionsthatassociatedwith
thoseactions.