Milestone LOGOS One User manual

LOGOS One
All-in-one Rapid Tissue Processor
Operator Manual
MM098
MILESTONE
HELPING
PATIENTS

Milestone s.r.l.
MM098-002 –LOGOS ONE –Operator Manual
3
Thank you for having selected our system and welcome to the ever growing world club of users for Milestone
laboratory instrumentation.
We are sure that you will be completely satisfied with this new tool entering your laboratory.
We invite you to read carefully this operator manual and to keep it in reach for convenient and fast
consulting.
For any possible clarification or any request for assistance please contact either our Representative in your
country:
Or contact
Milestone s.r.l.
Via Fatebenefratelli, 1/5
24010 Sorisole (BG) Italy
Tel. +39.035.412 8264
Fax [phone]
web site www.milestonemedsrl.com
e-mail [e-mail]
Please read the user manual before using the device.
MM098-002 –LOGOS ONE –Operator Manual
2015-07

Milestone s.r.l.
MM098-002 –LOGOS ONE –Operator Manual
4
SUMMARY
SUMMARY.................................................................................................................................................. 4
1INTRODUCTION .................................................................................................................................. 6
1.1 Symbol used................................................................................................................................. 6
1.2 Designated uses........................................................................................................................... 7
1.3 Technical specifications................................................................................................................ 7
1.3.1 Touch control terminal .............................................................................................................. 7
1.4 Transportation and storage conditions .......................................................................................... 8
1.5 Warning information...................................................................................................................... 9
1.6 Labeling explanation....................................................................................................................10
1.7 Compatible reagents....................................................................................................................10
1.8 Waste disposal of the equipment.................................................................................................11
2INSTALLATION...................................................................................................................................12
2.1 Space requirements.....................................................................................................................12
2.2 Unpacking and checking list.........................................................................................................13
2.3 Placement...................................................................................................................................15
2.3.1 Unit overview...........................................................................................................................15
2.4 Fumes extraction system.............................................................................................................16
2.5 Power supply...............................................................................................................................17
2.6 Electrical installation....................................................................................................................17
2.6.1 Back side connection plate 230V Version.................................................................................18
2.6.2 Back side connection plate 115V Version.................................................................................18
2.6.3 Main power supply connection.................................................................................................19
2.6.4 Power supply connection (NO UPS mode)...............................................................................19
2.6.5 Power supply connection (Local UPS mode)............................................................................20
2.7 Remote alarm connection............................................................................................................22
2.8 Internet connection......................................................................................................................22
2.9 Reagents.....................................................................................................................................24
2.10 Log in and log out........................................................................................................................24
2.10.1 Create a new user................................................................................................................25
2.11 Set system date and time ............................................................................................................27
2.12 Set language...............................................................................................................................27
2.13 Load LOGOS ONE with wax........................................................................................................28
2.13.1 Wax heating setting .............................................................................................................30
2.14 Load LOGOS ONE with reagents ................................................................................................32
2.14.1 Set up LOGOS ONE with reagents.......................................................................................33
2.14.2 Cleaning procedure for cleaning tanks .................................................................................39
2.15 Most used programs....................................................................................................................39
2.16 Owner settings ............................................................................................................................41
3OPERATE WITH LOGOS ONE............................................................................................................44
3.1 Loading cassettes into the rack....................................................................................................44
3.1.1 Rack loading-unloading tool.....................................................................................................45
3.2 Run a program ............................................................................................................................46
3.2.1 Run of the most used program.................................................................................................46
3.2.2 Run a standard program..........................................................................................................54
3.2.3 Run two processes simultaneously ..........................................................................................57
3.2.4 Run a program using the STEP START function......................................................................59
3.2.5 Run a DELAYED PROGRAM ..................................................................................................60
3.2.6 Add WAX.................................................................................................................................63
3.2.7 Screen saver ...........................................................................................................................64
3.3 Run a cleaning cycle of the main cavity........................................................................................65
3.3.1 Tanks for process and main cavity cleaning.............................................................................66
3.4 Reagents group and programs.....................................................................................................68
3.5 Run a cleaning cycle of the WAX.................................................................................................69
3.6 Retrieving saved processes.........................................................................................................71
3.6.1 How to delete a saved process................................................................................................74
3.7 Modify a program.........................................................................................................................74
3.7.1 Modify a standard program......................................................................................................75
3.7.2 Correlation between racks and programs.................................................................................76

Milestone s.r.l.
MM098-002 –LOGOS ONE –Operator Manual
5
3.7.3 Modify a main cavity cleaning program.....................................................................................78
3.7.4 Modify a WAX cleaning............................................................................................................79
4REAGENTS MANAGEMENT...............................................................................................................80
4.1 Reagents reuse life......................................................................................................................80
4.1.1 Reagents settings....................................................................................................................81
4.1.2 Recommendations for reuse life...............................................................................................82
4.2 Reagents replacement procedure................................................................................................83
4.2.1....................................................................................................................................................83
4.2.2 Reagent NOT USED FOR RINSING........................................................................................84
4.2.3 Reagent USED FOR RINSING................................................................................................86
4.2.4 Change reagents during a WAX phase ....................................................................................87
4.3 Wax replacement procedure........................................................................................................88
5SAFETY MODE PROCEDURE............................................................................................................90
5.1 Power failure ...............................................................................................................................90
5.2 Regent loading time-out...............................................................................................................92
6REPORTING .......................................................................................................................................94
6.1 Export processing from the terminal to the USB key.....................................................................94
6.2 Install and operate with the LogViewer.........................................................................................95
6.2.1 Open process..........................................................................................................................95
6.2.2 Print process............................................................................................................................97
6.2.3 Send process to customer support (Milestone).........................................................................98
6.2.4 Change settings.......................................................................................................................99
6.2.5 Other functions........................................................................................................................99
6.3 Reagents Log and Events Log from the terminal to the USB key................................................100
7MAINTENANCE.................................................................................................................................102
7.1 Introduction ...............................................................................................................................102
7.2 After each run............................................................................................................................102
7.2.1 Rack cleaning procedure .......................................................................................................102
7.3 Every 5 runs..............................................................................................................................104
7.4 Weekly......................................................................................................................................104
7.5 Monthly .....................................................................................................................................105
7.6 Yearly........................................................................................................................................107
7.7 How to start the remote assistance............................................................................................107
8OPTIONAL ........................................................................................................................................108
9GOOD TISSUE PROCESSING PRACTICE.......................................................................................112
9.1 Specimens ................................................................................................................................112
9.2 Fixation .....................................................................................................................................112
9.3 Beware......................................................................................................................................113
9.4 Reagents...................................................................................................................................114
9.4.1 Alcohols quality......................................................................................................................114
9.5 Tissue processing selection guidelines ......................................................................................115
9.6 Presoaking guidelines................................................................................................................116
A. Appendix.......................................................................................................................................118
A.1. TISSUE PROCESSING THROUBLESHOOTING GUIDE...........................................................118
A.2. OVERVIEW OF HISTOPROCESSING TROUBLE SHOOTING..................................................125
B. Appendix.......................................................................................................................................126
B.1. HOW TO MANAGE AN ALARM.................................................................................................126
C. Appendix.......................................................................................................................................128
C.1. HOW TO MANAGE SAMPLES WHILE AN ALARM IS OCCURRING.........................................128