Milestone UltraGROSS User manual

UltraGROSS
Modular Grossing Station
Operator Manual - MM182
MILESTONE
HELPING
PATIENTS

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MM182-001 –Operator Manual
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Thank you for choosing one of our systems and welcome to the growing club of users of Milestone laboratory
instruments.
We feel confident that you will be fully satisfied with this new instrument in your laboratory.
We recommend that you read this operator manual carefully and that you always keep it within reach for quick
and convenient reference.
For any clarification or request for support please contact our Representative in your country:
You can also contact us directly at:
Milestone s.r.l.
Via Fatebenefratelli, 1/5
24010 Sorisole (BG) Italy
Tel. +39.035.412 8264
Fax [phone]
Website www.milestonemed.com
e-mail [e-mail]
Please read this user manual carefully before using the instrument.
MM182-001 - UltraGROSS - Operator Manual
2021-11

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MM182-001 –Operator Manual
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INDEX
INDEX ................................................................................................................................................................ 4
1. INTRODUCTION ........................................................................................................................................ 7
1.1. Symbols used .................................................................................................................................... 7
1.2. Intended use ...................................................................................................................................... 9
1.3. Technical specifications................................................................................................................... 10
1.3.1. Default models ......................................................................................................................... 10
1.3.2. Custom models ........................................................................................................................ 17
1.3.3. Technical specifications........................................................................................................... 19
1.4. Compatible reagents........................................................................................................................ 24
1.5. Transport and storage conditions .................................................................................................... 24
1.6. Antivirus ........................................................................................................................................... 24
1.7. Warnings.......................................................................................................................................... 25
1.7.1. Personal data safety ................................................................................................................ 25
1.8. MacroPATH data backup................................................................................................................. 25
1.9. Instrument label ............................................................................................................................... 26
2. INSTALLING UltraGROSS ....................................................................................................................... 27
2.1. Environmental requirements............................................................................................................ 28
2.2. Clearance requirements for initial code with 180 ............................................................................ 30
2.3. Clearance requirements for initial code with 150 ............................................................................ 31
2.4. Unpacking and check list ................................................................................................................. 32
2.5. UltraGROSS installation .................................................................................................................. 37
2.5.1. Safety shield block ................................................................................................................... 37
2.5.2. Camera installation (only letter C) ........................................................................................... 38
2.5.3. Installing the barcode reader, foot pedal and microphone ...................................................... 42
2.5.4. Installation of keyboard support arm (only for letter S)............................................................ 43
2.5.5. Installation of keyboard support arm (only for letter H) ........................................................... 46
2.5.6. Installation of touch screen PC (only for letter T in code)........................................................ 49
2.5.7. Parts to be assembled ............................................................................................................. 52
2.5.8. Connection to the hydraulic system –Water inlet ................................................................... 57
2.5.9. Connection to the hydraulic system –Water drain .................................................................. 58
2.5.10. Connection to the fume extraction system –Active hood (letter A)......................................... 59
2.5.11. Connection to the fume extraction system –Passive hood (letter P)...................................... 60
2.5.12. Connection to the fixative loading system ............................................................................... 63
2.5.13. Connection to the fixative drain system ................................................................................... 65
2.5.14. Shower tap installation............................................................................................................. 67
2.5.15. Installing second tap ................................................................................................................ 68
2.5.16. Switching on the UltraGROSS unit .......................................................................................... 68
2.5.17. Installation checks ................................................................................................................... 69
2.6. Description of the unit’s software..................................................................................................... 70
2.6.1. Alarms/Warnings for the operator............................................................................................ 77
2.6.2. External files ............................................................................................................................ 79
2.6.3. Log in and log out .................................................................................................................... 80
2.6.4. Users........................................................................................................................................ 80
2.6.5. General settings....................................................................................................................... 82
2.6.6. Language ................................................................................................................................. 90
2.6.7. Help.......................................................................................................................................... 90
2.6.8. Maintenance ............................................................................................................................ 91
2.6.9. System settings........................................................................................................................ 91
2.6.10. Remote assistance .................................................................................................................. 93
2.6.11. Events log ................................................................................................................................ 94
2.7. Installing and using the LogVIEWER............................................................................................... 96
2.7.1. How to use LogVIEWER.......................................................................................................... 97
2.8. Description of UltraGROSS ............................................................................................................. 99
2.8.1. Front view ................................................................................................................................ 99
2.8.2. Rear view ............................................................................................................................... 108
3. OPERATING WITH MacroPath SOFTWARE ........................................................................................ 111
4. MAINTENANCE, CLEANING AND DECONTAMINATION.................................................................... 112
4.1. UltraGROSS cleaning precautions ................................................................................................ 112
4.2. Operating procedure with SUPRASPOR....................................................................................... 114
4.2.1. MANUAL operating procedure............................................................................................... 115

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4.2.2. AUTOMATIC operating procedure ........................................................................................ 115
4.3. Operating procedure with 70% alcohol-based reagent ................................................................. 116
4.4. Preventive maintenance ................................................................................................................ 116
5. OPTIONAL PARTS AND SPARE PARTS ............................................................................................. 117
5.1. Shelves .......................................................................................................................................... 117
5.2. Ventilated waste paper bin ............................................................................................................ 119
5.3. Filterbox Kit with HEPA filter.......................................................................................................... 120
5.4. Filterbox Kit .................................................................................................................................... 123
5.5. Kit 3 Internal Activated Charcoal Filters ........................................................................................ 124
5.6. Kit 2 Internal Activated Charcoal Filters ........................................................................................ 126
5.7. Kit 3 Internal HEPA H14 Filters ..................................................................................................... 127
5.8. Kit 2 Internal HEPA H14 Filters ..................................................................................................... 128
5.9. USB Bar code reader 2D (includes holder) ................................................................................... 129
5.10. Waste Grinder................................................................................................................................ 130
5.10.1. Installation specifications ....................................................................................................... 130
5.10.2. How to install the Waste disposal unit on UltraGROSS ........................................................ 131
5.10.3. Warnings................................................................................................................................ 135
5.10.4. How to use the Waste disposal unit correctly........................................................................ 135
5.10.5. Maintenance .......................................................................................................................... 135
5.10.6. Troubleshooting ..................................................................................................................... 136
5.11. Polarised Lens for Camera (only for letter C) ................................................................................ 137
5.12. USB Water proof (sealed) keyboard.............................................................................................. 137
5.13. MacroPATH licenses (only for letter C) ......................................................................................... 138
5.14. LOOX Eye-Control for MacroPATH (only for letter C) ................................................................... 138
5.15. Mouse wireless optical in silicone.................................................................................................. 139
5.16. Double Arm Led Lamp................................................................................................................... 140
5.17. Conveyor Kit .................................................................................................................................. 141
5.18. Keyboard support .......................................................................................................................... 141
5.19. Inlet water pressure regulator ........................................................................................................ 142
5.20. Foot Tap with hoses and support .................................................................................................. 142
5.21. Follow Me, Movable magnetic Bar ................................................................................................ 143
5.22. Superior Monitor and Keyboard Arm ............................................................................................. 143
5.23. Lateral Monitor and Keyboard Arm................................................................................................ 143
5.24. Keyboard Arm with Block notes support........................................................................................ 144
5.25. Stainless steel Shelf ...................................................................................................................... 145
5.26. Fixed Magnetic Bar ........................................................................................................................ 145
5.27. Gooseneck magnifying glass with LED lighting and clip ............................................................... 146
5.28. Second tap unit .............................................................................................................................. 146
5.29. Shower tap..................................................................................................................................... 147
5.30. Shower tap pipe ............................................................................................................................. 147
5.31. VIROCLEAN .................................................................................................................................. 148
5.32. SUPRASPOR ................................................................................................................................ 150
5.33. Ink holder plate .............................................................................................................................. 151
5.34. Tank 10 liters for exhaust Formalin ............................................................................................... 151
5.35. Wastewater pipe ............................................................................................................................ 151
5.36. Exhaust fumes pipe ....................................................................................................................... 152
5.37. Fixative loading pedal .................................................................................................................... 152
5.38. Drain filter....................................................................................................................................... 152
5.39. Ventilated surface filter .................................................................................................................. 152
5.40. Set of Allen screws ........................................................................................................................ 153
5.41. Foot Pedal (only for letter C).......................................................................................................... 153
5.42. Wrench 8-10 mm ........................................................................................................................... 153
5.43. Sizing ruler ..................................................................................................................................... 153
5.44. Spare Lens +1,5 (only for letter C) ................................................................................................ 153
5.45. Microphone .................................................................................................................................... 154
5.46. Loading tank steel safety cable ..................................................................................................... 154
5.47. Glass disassembly spanner........................................................................................................... 154
5.48. Touch-Pen (only for letter T).......................................................................................................... 154
5.49. Fixative drain closing cap .............................................................................................................. 155
5.50. Anti-seismic bracket....................................................................................................................... 155
5.51. Networking Web Managed Switch................................................................................................. 157
5.51.1. Description ............................................................................................................................. 157

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5.51.2. Technical specifications......................................................................................................... 159
5.51.3. Installation instructions .......................................................................................................... 160
6. TROUBLESHOOTING ........................................................................................................................... 161
6.1. Milestone remote connection......................................................................................................... 161
6.2. Return for repair to the manufacturer ............................................................................................ 161
7. WASTE DISPOSAL................................................................................................................................ 162
7.1. Waste disposal of SUPRASPOR bottles ....................................................................................... 162
7.2. Waste disposal of SUPRASPOR................................................................................................... 162
7.3. Disposal of used fixative ................................................................................................................ 162
7.4. Waste disposal of filters (if present) .............................................................................................. 162
8. DISPOSING OF THE UNIT .................................................................................................................... 163
The manufacturer reserves the right to change and/or improve specifications without notice
and without incurring any obligation.

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1. INTRODUCTION
1.1. Symbols used
The instructions marked by this symbol are important and must be read carefully.
An instruction marked by this WARNING symbol means caution is required. Failure to
follow the instruction may endanger the user or cause damage to the instrument.
An instruction marked with this symbol means caution is required as there is an electric
shock hazard. Carefully follow the instruction in order to prevent this kind of accident.
Biohazard: pay attention when performing a procedure marked with this symbol, as
there is biological contamination hazard.
Attention, risk of hand crushing.
Attention, toxic substance.
CE Logo: this instrument complies with European Community directives.
Specifies the manufacturer’s serial number.
Hot water (UNI EN 13792).
Cold water (UNI EN 13792).
Formaldehyde (UNI EN 13792).
Avoid sprays and direct jets.
WEEE European directive (2012/19/EC) symbol:
electric/electronic material, do not release into the environment.
Authorized and qualified customer support personnel only.

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Fragile.
USB PORT.
Ethernet port.
ON.
OFF.
Do not push.

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1.2. Intended use
UltraGROSS is an ergonomic histopathology workstation dedicated to the preparation and cutting of pieces.
The table has a ventilation system and various optional parts that are defined in the following manual.
One or more cameras with MacroPATH software can be mounted on UltraGROSS (depending on the selected
model).
MacroPATH has been designed to carry out complete, safe and reliable image handling of gross histological
specimens.
The system has been designed for use in a laboratory and can therefore withstand the harshest laboratory
conditions (indoor use only).
UltraGROSS is a system that must be operated by trained personnel, such as: laboratory technicians and
pathologists.
MacroPATH's measurement function is strictly linked to the calibration performed by the
operator and is not controlled by the unit's software. That is why the measurements of the
specimen obtained with MacroPATH CANNOT be taken into account for diagnostic
purposes. These values are purely indicative.
Indeed, a ruler must be placed near the specimen (see image below) or a gauge must be used to
obtain a diagnostic value for the growth of the tumor, the extent of the lesion, etc.
The system must be calibrated in order to perform measurements with MacroPATH (refer to MM161
operator manual supplied with the unit).

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1.3. Technical specifications
1.3.1. Default models
This chapter lists the different UltraGROSS default models with relative codes, explaining their structure.
fixed field
selectable and mandatory field
selectable and non-mandatory field
MALPIGHI Version 180
Identifier
Description
J
U
A
E
P
K
180
/M
P
Passive
ventilation unit
A
Active ventilation
unit
J
Power supply unit
100V 50/60Hz JIS
(Japan)
U
Power supply unit
NEMA 115V~
60Hz
E
Power supply unit
Schuko 220-
240V~ 50/60Hz
K
Power supply unit
BS 220-240V~
50/60Hz
/M
Including:
1X washbasin
500mm with two
covers,
1X grid plate
500mm with
cutting board
500mm,
2X grid plates
250mm,
1X shelf,
1X fixed magnetic
bar,
1X mobile
magnetic bar

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MALPIGHI Version 150
Identifier
Description
J
U
A
E
P
K
150
/M
P
Passive
ventilation unit
A
Active ventilation
unit
J
Power supply unit
100V 50/60Hz JIS
(Japan)
U
Power supply unit
NEMA 115V~
60Hz
E
Power supply unit
Schuko 220-
240V~ 50/60Hz
K
Power supply unit
BS 220-240V~
50/60Hz
/M
Including:
1X washbasin
250mm with
cover,
1X grid plate
500mm with
cutting board
500mm,
1X grid plate
250mm,
1X shelf,
1X fixed magnetic
bar,
1X mobile
magnetic bar

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GOLGI Version 180
Identifier
Description
J
U
A
E
P
K
180
CSDR
/G
CSDR
C: MacroPATH Basic
S: Monitor and keyboard
side support
D: Fixative drain unit
R: Drain unit mounted on
right
P
Passive ventilation unit
A
Active ventilation unit
J
Power supply unit 100V
50/60Hz JIS (Japan)
U
Power supply unit NEMA
115V~ 60Hz
E
Power supply unit Schuko
220-240V~ 50/60Hz
K
Power supply unit BS
220-240V~ 50/60Hz
/G
Including:
1X washbasin 500mm
with two covers,
1X grid plate 500mm with
cutting board 500mm,
1X grid plate 250mm,
1X fixative drain funnel
250mm,
1X shelf,
1X fixed magnetic bar,
1X mobile magnetic bar,
1X keyboard

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GOLGI Version 150
Identifier
Description
J
U
A
E
P
K
150
CSDR
/G
CSDR
C: MacroPath Basic
S: Monitor and keyboard
side support
D: Fixative drain unit
R: Drain unit mounted on
right
P
Passive ventilation unit
A
Active ventilation unit
J
Power supply unit 100V
50/60Hz JIS (Japan)
U
Power supply unit NEMA
115V~ 60Hz
E
Power supply unit Schuko
220-240V~ 50/60Hz
K
Power supply unit BS
220-240V~ 50/60Hz
/G
Including:
1X washbasin 250mm
with cover,
1X grid plate 500mm with
cutting board 500mm,
1X fixative drain funnel
250mm,
1X shelf,
1X fixed magnetic bar,
1X mobile magnetic bar,
1X keyboard

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ROSAI Version 180
Identifier
Description
J
U
A
E
P
K
180
CTSDFR
/R
CTSDFR
C: MacroPath Basic
T: 19” touch screen PC
S: Monitor and keyboard
side support
D: Fixative drain unit
F: Fixative loading unit
R: Drain/loading unit
mounted on right
P
Passive ventilation unit
A
Active ventilation unit
J
Power supply unit 100V
50/60Hz JIS (Japan)
U
Power supply unit NEMA
115V~ 60Hz
E
Power supply unit Schuko
220-240V~ 50/60Hz
K
Power supply unit BS
220-240V~ 50/60Hz
/R
Including:
1x washbasin 500mm with
two covers,
1x grid plate 500mm with
cutting board 500mm,
1X grid plate 250mm,
1X fixative drain funnel
250mm,
1X shelf,
1X fixed magnetic bar,
1X mobile magnetic bar
1X keyboard

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ROSAI Version 150
Identifier
Description
J
U
A
E
P
K
150
CTSDFR
/R
CTSDFR
C: MacroPath Basic
T: 19” touch screen PC
S: Monitor and keyboard
side support
D: Fixative drain unit
F: Fixative loading unit
R: Drain/loading unit
mounted on right
P
Passive ventilation unit
A
Active ventilation unit
J
Power supply unit 100V
50/60Hz JIS (Japan)
U
Power supply unit NEMA
115V~ 60Hz
E
Power supply unit Schuko
220-240V~ 50/60Hz
K
Power supply unit BS
220-240V~ 50/60Hz
/R
Including:
1X washbasin 250mm
with cover,
1X grid plate 500mm with
cutting board 500mm,
1X fixative drain funnel
250mm,
1X shelf,
1X fixed magnetic bar,
1X mobile magnetic bar,
1X keyboard

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VIRCHOW Version 180 Version 150 does not exist.
Identifier
Description
J
U
A
E
P
K
180
2CTSDF
/V
2CTSDF
2: doubles the amount of
letters below
C: MacroPath Basic
T: 19” touch screen PC
S: Monitor and keyboard side
support
D: Fixative drain unit
F: Fixative loading unit
P
Passive ventilation unit
A
Active ventilation unit
J
Power supply unit 100V
50/60Hz JIS (Japan)
U
Power supply unit NEMA
115V~ 60Hz
E
Power supply unit Schuko
220-240V~ 50/60Hz
K
Power supply unit BS 220-
240V~ 50/60Hz
/V
Including:
1X washbasin 500mm with
two covers,
1X LH grid plate with funnel
500mm and cutting board
500mm,
1X RH grid plate with funnel
500mm and cutting board
500mm,
2X shelves,
1X second tap,
2X fixed magnetic bar,
2X mobile magnetic bar
2X keyboard

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1.3.2. Custom models
This chapter lists the different UltraGROSS customized models with relative codes, explaining their structure.
fixed field
selectable and mandatory field
selectable and non-mandatory field
UltraGROSS 150
Identifier
Description
J
U
H
R
A
E
C
T
S
D
F
L
P
K
150
C
MacroPath Basic
T
19” touch screen PC
S
Monitor and keyboard
side support
H
Monitor and keyboard
top support
D
Fixative drain unit
F
Fixative loading unit
L
Fixative
drain/unloading unit
mounted on left
R
Fixative
drain/unloading unit
mounted on right
P
Passive ventilation
unit
A
Active ventilation unit
J
Power supply unit
100V 50/60Hz JIS
(Japan)
U
Power supply unit
NEMA 115V~ 60Hz
E
Power supply unit
Schuko 220-240V~
50/60Hz
K
Power supply unit BS
220-240V~ 50/60Hz

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UltraGROSS 180
Identifier
Description
J
U
H
H
A
E
C
T
S
D
F
L
C
T
S
D
F
R
P
K
180
C
MacroPath Basic
T
19” touch screen PC
S
Monitor and keyboard
side support
H
Monitor and keyboard
top support
D
Fixative drain unit
F
Fixative loading unit
L
Left workstation –
refers to previous
letters
C
SK camera
T
19” touch screen PC
S
Monitor and keyboard
side support
H
Monitor and keyboard
top support
D
Fixative drain unit
F
Fixative loading unit
R
Right workstation –
refers to previous
letters
P
Passive ventilation
unit
A
Active ventilation unit
J
Power supply unit
100V 50/60Hz JIS
(Japan)
U
Power supply unit
NEMA 115V~ 60Hz
E
Power supply unit
Schuko 220-240V~
50/60Hz
K
Power supply unit BS
220-240V~ 50/60Hz
For the grid plates of both versions, refer to the optional parts (see chapter 5.1).

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1.3.3. Technical specifications
For letters that refer to unit codes, see chapter 1.3.1.
For voltage and frequency in reference to letters E customizable like K (220-240V~ 50/60Hz) the power is:
•2600W if letter (A) active 1819BTU/h,
•1070W if letter (P) passive 512BTU/h.
For voltage and frequency in reference to letter U (115V~ 60Hz) the power is:
•2160W if letter (A) active 1836BTU/h,
•610W if letter (P) passive 512BTU/h.
For voltage and frequency in reference to letter J (100V~ 50/60Hz) the power is:
•1500W if letter (A) active 1666BTU/h,
•150W f letter (P) passive 512BTU/h.
For codes that start with 180:
oIf letter A: Weight:350Kg –771.61lb,
oIf letters A and C: weight 375Kg –826.73lb,
oIf letter P: weight :325Kg –716.50lb,
oIf letters P and C: weight 350Kg –771.61lb,
oFor VIRCHOW model, if letter A, weight 400Kg –881.84lb,
oFor VIRCHOW model, if letter P, weight 375Kg –826.73lb.
For codes that start with 150:
oIf letter A: Weight:325Kg –716.50lb,
oIf letters A and C: weight 350Kg –771.61lb,
oIf letter P: weight :300Kg –661.38lb,
oIf letters P and C: weight 325Kg –716.50lb.
For the sizes of all models, see chapters 2.2 and 2.3.
Lighting
- LED illumination of the work area
- Average work area illuminance 1600 lux*
* with environmental conditions of 400 Lux and units with all lights on
- Uniformity U=0,9
- Color rendering index Ra=70
Structure
- Work surfaces in AISI 316 stainless steel (listed in chapter 5.1).
- Structure in AISI 304 stainless steel
- Antibacterial paint
-Work surface height adjustable from 85cm to 115cm
- Telescopic columns (Protection rating IPx6)
- Safety shield in shatterproof glass
- Tap with clinical lever
- Shelf
- Magnetic holder bar
- The instrument has 6 casters
- Object shelf outside of work surface
Types of seat (EN 14738:2009)
Compatible with machine ergonomics:
- Lifted sitting seat.
- Upright posture with support.
- Upright posture.

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Sound power
Units with letter A installed without internal filters with air speed of 0.5m/s, the sound level is 55dbA at a
distance of 1metre with work surface 900mm high.
Electrical connections
The power supply line needs to be earthed (Class I device).
115V60Hz: Power supply line protection: residual current circuit breaker curve C20, residual current: 30mA.
220-240V50/60Hz: Power supply line protection: residual current circuit breaker curve C16, residual current:
30mA.
100V50/60Hz: Power supply line protection: residual current circuit breaker curve C15, residual current:
30mA.
2m power cord.
Letter J: JIS plug (JIS 8303)
Letter K: BS plug (BS1363/A)
Letter U: NEMA plug (NEMA 5-20)
Letter E: Schuko plug (DIN/VDE 0620)
Hydraulic connections
-1X Hot water inlet: 1/2’’ female
-1X Cold water inlet: 1/2’’ female
-Maximum water inlet pressure: 0.6 bar
-Fluid temperature MIN: +2 °C MAX 52 °C
-Wastewater drain: 40mm pipe
Ventilation
The ventilation system is applied in 3 distinct parts that cannot be excluded:
-Work surface area (downdraft) in blue
-Area on the panel behind the work surface (backdraft) in green
-Area dedicated to the "waste” bin (optional part - see chapter 5.2) in pink
The fluxes of these 3 exhaust zones are ejected at the back by 2 pipes (inside diameter from 160mm length
4metres). The two pipes can be connected in a coupling with a 200mm outlet (optional, see chapter 5.17).