Qiagen PowerLyzer 24 User manual

Sample to Insight__
September 2018
PowerLyzer®24
Homogenizer
User Manual
For lysis and homogenization of biological samples
contained in bead beating tubes at variable speeds

PowerLyzer 24 Homogenizer User Manual 09/2018
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Contents
Safety Information ..................................................................................................... 5
Proper use...................................................................................................... 6
Biological safety ............................................................................................. 7
Samples.................................................................................................... 7
Toxic fumes ............................................................................................... 9
Waste disposal............................................................................................... 9
Mechanical hazards........................................................................................ 9
Symbols on the PowerLyzer 24 Homogenizer ................................................... 10
Translations of warnings and cautions.............................................................. 10
Introduction ............................................................................................................ 23
Intended use of the PowerLyzer 24 Homogenizer .............................................. 23
Requirements for PowerLyzer 24 Homogenizer users .................................... 23
General Description................................................................................................. 24
Features of the PowerLyzer 24 Homogenizer system .......................................... 24
Installation Procedures ............................................................................................. 24
Parts............................................................................................................ 24
Unpacking the PowerLyzer 24 Homogenizer .................................................... 25
Installation ................................................................................................... 28
Transport ..................................................................................................... 30
Transporting the PowerLyzer 24 Homogenizer ............................................. 30
Decontamination...................................................................................... 31
Operating Procedures.............................................................................................. 32

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PowerLyzer 24 Homogenizer User Manual 09/2018
Tube motion ................................................................................................. 32
Programming................................................................................................ 33
Keypad layout .............................................................................................. 33
Startup of the equipment ................................................................................ 34
Loading sample tubes .................................................................................... 36
Program settings ........................................................................................... 38
Adjusting parameters..................................................................................... 40
Adjusting the speed.................................................................................. 40
Adjusting the run time............................................................................... 41
Adjusting the number of cycles................................................................... 41
Adjusting the pause or “dwell” between cycles ............................................ 42
Recommended settings................................................................................... 44
Homogenizer speed conversion table .............................................................. 45
Maintenance Procedures .......................................................................................... 46
Regular maintenance..................................................................................... 46
Replacing the fuse(s)...................................................................................... 46
Cleaning and decontamination....................................................................... 47
Decontamination procedure....................................................................... 48
Troubleshooting Guide............................................................................................. 49
General troubleshooting................................................................................. 49
Appendix A............................................................................................................ 50
Technical data.............................................................................................. 50
Environmental conditions................................................................................ 50
Operating conditions................................................................................ 50

PowerLyzer 24 Homogenizer User Manual 09/2018
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Storage conditions ................................................................................... 50
Mechanical data........................................................................................... 50
Waste Electrical and Electronic Equipment (WEEE)............................................ 51
FCC declaration ........................................................................................... 52
Declaration of Conformity .............................................................................. 53
Appendix B............................................................................................................ 54
Warranty statement....................................................................................... 54
Liability clause.............................................................................................. 55
Appendix C ........................................................................................................... 56
Decontamination certificate ....................................................................... 56

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PowerLyzer 24 Homogenizer User Manual 09/2018
Safety Information
Before using the PowerLyzer 24 Homogenizer system, it is essential that you read this user
manual carefully and pay particular attention to the safety information. The instructions and
safety information in the user manual must be followed to ensure safe operation of the
PowerLyzer 24 Homogenizer and to maintain the PowerLyzer 24 Homogenizer in a safe
condition.
The following types of safety information appear throughout this user manual.
WARNING
The term WARNING is used to inform you about situations that could
result in personal injury to you or other persons.
Details about these circumstances are given in a box like this one.
CAUTION
The term CAUTION is used to inform you about situations that could
result in damage to the PowerLyzer 24 or other equipment.
Details about these circumstances are given in a box like this one.
Each warning (W) or caution (C) can be identified by a reference number mentioned at the
top right corner of their respective boxes (e.g., [W1], [C1], etc.).
The advice given in this manual is intended to supplement, not supersede, the normal safety
requirements prevailing in the user’s country.