Waters Pump Control Module II User manual

Waters Pump Control
Module II
Installation Guide
71500078604/Revision B
Copyright © Waters Corporation 2009
All rights reserved

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Copyright notice
© 2009 WATERS CORPORATION. PRINTED IN THE UNITED STATES OF
AMERICA AND IRELAND. ALL RIGHTS RESERVED. THIS DOCUMENT
OR PARTS THEREOF MAY NOT BE REPRODUCED IN ANY FORM
WITHOUT THE WRITTEN PERMISSION OF THE PUBLISHER.
The information in this document is subject to change without notice and
should not be construed as a commitment by Waters Corporation. Waters
Corporation assumes no responsibility for any errors that may appear in this
document. This document is believed to be complete and accurate at the time
of publication. In no event shall Waters Corporation be liable for incidental or
consequential damages in connection with, or arising from, its use.
Trademarks
Millennium and Waters are registered trademarks of Waters Corporation,
and Empower, LAC/E, SAT/IN, and “THE SCIENCE OF WHAT’S
POSSIBLE.” are trademarks of Waters Corporation.
Other registered trademarks or trademarks are the sole property of their
owners.

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Customer comments
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errors you encounter in this document or to suggest ideas for otherwise
improving it. Please help us better understand what you expect from our
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usability.
We seriously consider every customer comment we receive. You can reach us
at [e-mail].

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Contacting Waters
Contact Waters®with enhancement requests or technical questions regarding
the use, transportation, removal, or disposal of any Waters product. You can
reach us via the Internet, telephone, or conventional mail.
Safety considerations
Some reagents and samples used with Waters instruments and devices can
pose chemical, biological, and radiological hazards. You must know the
potentially hazardous effects of all substances you work with. Always follow
Good Laboratory Practice, and consult your organization’s safety
representative for guidance.
When you develop methods, follow the “Protocol for the Adoption of Analytical
Methods in the Clinical Chemistry Laboratory,” American Journal of Medical
Technology, 44, 1, pages 30–37 (1978). This protocol addresses good operating
procedures and the techniques necessary to validate system and method
performance.
Waters contact information
Contacting medium Information
Internet The Waters Web site includes contact
information for Waters locations worldwide.
Visit www.waters.com, and click Waters
Division > Contact Waters Online.
Telephone and fax From the USA or Canada, phone 800
252-HPLC, or fax [phone].
For other locations worldwide, phone and fax
numbers appear in the Waters Web site.
Conventional mail Waters Corporation
34 Maple Street
Milford, MA 01757
USA

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Safety advisories
Consult Appendix A for a comprehensive list of warning and caution
advisories.
Operating the Waters Pump Control Module II
When operating the Pump Control Module II, follow standard quality-control
(QC) procedures and the guidelines presented in this section.
Applicable symbols
Audience and purpose
This guide is intended for use by individuals whose familiarity with HPLC
ranges from novice to expert. It describes how to install the Pump Control
Module II in a multi-pump gradient system with up to three pumps controlled
by a Waters data control system.
Intended use of the Pump Control Module II
Waters designed the Pump Control Module II to provide programmable
control through a Waters data system of up to three, 500-series high-pressure
pumps.
Calibrating
To calibrate LC systems, follow acceptable calibration methods using at least
five standards to generate a standard curve. The concentration range for
standards should include the entire range of QC samples, typical specimens,
and atypical specimens.
Symbol Definition
Confirms that a manufactured product complies
with all applicable European Community
directives
Australia C-Tick EMC Compliant
ABN 49 065 444 751

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To calibrate mass spectrometers, consult the calibration section for the
operator’s guide of the instrument you are calibrating.
Quality-control
Routinely run three QC samples that represent subnormal, normal, and
above-normal levels of a compound. Ensure that QC sample results fall within
an acceptable range, and evaluate precision from day to day and run to run.
Data collected when QC samples are out of range might not be valid. Do not
report these data until you are certain that the instrument performs
satisfactorily.
ISM classification
ISM Classification: ISM Group 1 Class B
This classification has been assigned in accordance with CISPR 11 Industrial
Scientific and Medical, (ISM) instruments requirements. Group 1 products
apply to intentionally generated and/or used conductively coupled
radio-frequency energy that is necessary for the internal functioning of the
equipment. Class B products are suitable for use in both commercial and
residential locations and can be directly connected to a low voltage,
power-supply network.

Table of Contents 1
Copyright notice ................................................................................................... ii
Trademarks ............................................................................................................ ii
Customer comments ............................................................................................ iii
Contacting Waters ............................................................................................... iv
Safety considerations .......................................................................................... iv
Safety advisories.................................................................................................. v
Operating the Waters Pump Control Module II ......................................... i-v
Applicable symbols .............................................................................................. v
Audience and purpose.......................................................................................... v
Intended use of the Pump Control Module II..................................................... v
Calibrating ........................................................................................................... v
Quality-control.................................................................................................... vi
ISM classification .............................................................................................. i-vi
ISM Classification: ISM Group 1 Class B ......................................................... vi
1 Overview .................................................................................................. 1-1
Introduction ....................................................................................................... 1-2
System configurations ..................................................................................... 1-3
Ethernet configuration.................................................................................... 1-3
IEEE-488 configuration................................................................................... 1-4
Signal conditions .............................................................................................. 1-5
2 Installing the Pump Control Module II ............................................ 2-1
Selecting the site and unpacking .................................................................. 2-2
Selecting the site.............................................................................................. 2-2
Unpacking and inspecting the module ........................................................... 2-2
Rear-panel signal connections ....................................................................... 2-3
Ethernet signal cable connections .................................................................. 2-4
Table of Contents

2 Table of Contents
IEEE-488 signal cable connections................................................................. 2-5
Connecting the pumps..................................................................................... 2-7
Connecting the event cables............................................................................ 2-8
Powering-on the module ............................................................................... 2-12
Programming the module ............................................................................. 2-14
Maintenance and troubleshooting .............................................................. 2-14
Cleaning the cabinet...................................................................................... 2-14
Replacing the fuse.......................................................................................... 2-14
Troubleshooting ............................................................................................. 2-15
A Safety Advisories .................................................................................. A-1
Warning symbols ............................................................................................... A-2
Task-specific hazard warnings........................................................................ A-2
Warnings that apply to particular instruments, instrument components, and
sample types............................................................................................... A-3
Caution symbol .................................................................................................. A-5
Warnings that apply to all Waters instruments ......................................... A-5
Electrical and handling symbols ................................................................. A-12
Electrical symbols.......................................................................................... A-12
Handling symbols .......................................................................................... A-13
B Specifications ........................................................................................ B-1
Physical and environmental specifications ............................................... B-2
Accuracy and precision .................................................................................. B-2
Electrical specifications ................................................................................. B-3
Protection Class 1 ............................................................................................ B-3
Overvoltage Category II .................................................................................. B-3
Pollution Degree 2 ........................................................................................... B-3
Moisture protection – Normal (IPXO) ............................................................ B-3
AC-to-DC power specifications ..................................................................... B-4
C Spare Parts ............................................................................................ C-1

1-1
1Overview
Contents
Topic Page
Introduction 1-2
System configurations 1-3
Signal conditions 1-5

1-2 Overview
Introduction
The Waters®Pump Control Module II is an HPLC pump controller. Through
the medium of Waters data system software, it offers programmatic control of
high-pressure-mixing pumps in HPLC and MS systems.
Pump Control Module II
Depending on your pump configuration requirements, you can attach as many
as three Waters 510 or 515 HPLC Pumps to the module and regulate the
solvent composition and flow rates by programming instrument method
settings in Empower, Millennium, or MassLynx data control software. (For
the module’s firmware/software requirements, see the Waters Pump Control
Module II release notes.)
A single Waters 510 or 515 Pump in an HPLC system is ideal for
high-throughput isocratic analyses. When you control two or three of these
pumps through a data system and external controller, you can achieve
reproducible, multipump gradient delivery with exceptionally smooth
concurrent-stream blending.
TP02342