Agilent Technologies 850-DS User manual

850-DS
Dissolution Sampling Station
Operator’s Manual

Notices
Manual Part Number
70-9074 Rev D
March 2018
Copyright
© Agilent Technologies, Inc. 2018
No part of this manual may be
reproduced in any form or by any means
(including electronic storage and retrieval
or translation into a foreign language)
without prior agreement and written
consent from Agilent Technologies, Inc.
as governed by United States and
international copyright laws.
Agilent Technologies, Inc.
3501 Stevens Creek Blvd.
Santa Clara, CA 95052 USA
Warranty
The material contained in this document
is provided “as is,” and is subject to being
changed, without notice, in future
editions. Further, to the maximum extent
permitted by applicable law, Agilent
disclaims all warranties, either express or
implied, with regard to this manual and
any information contained herein,
including but not limited to the implied
warranties of merchantability and fitness
for a particular purpose. Agilent shall not
be liable for errors or for incidental or
consequential damages in connection
with the furnishing, use, or performance
of this document or of any information
contained herein. Should Agilent and the
user have a separate written agreement
with warranty terms covering the
material in this document that conflict
with these terms, the warranty terms in
the separate agreement shall control.
Technology Licenses
The hardware and/or software described
in this document are furnished under a
license and may be used or copied only in
accordance with the terms of such
license.
Restricted Rights Legend
U.S. Government Restricted Rights.
Software and technical data rights
granted to the federal government
include only those rights customarily
provided to end user customers. Agilent
provides this customary commercial
license in Software and technical data
pursuant to FAR 12.211 (Technical Data)
and 12.212 (Computer Software) and, for
the Department of Defense, DFARS
252.227-7015 (Technical Data -
Commercial Items) and DFARS
227.7202-3 (Rights in Commercial
Computer Software or Computer
Software Documentation).
Safety Notices
CAUTION
A CAUTION notice denotes a
hazard. It calls attention to an
operating procedure, practice, or
the like that, if not correctly
performed or adhered to, could
result in damage to the product or
loss of important data. Do not
proceed beyond a CAUTION
notice until the indicated
conditions are fully understood
and met.
WARNING
A WARNING notice denotes a
hazard. It calls attention to an
operating procedure, practice, or
the like that, if not correctly
performed or adhered to, could
result in personal injury or death.
Do not proceed beyond a
WARNING notice until the
indicated conditions are fully
understood and met.

850-DS Operator’s Manual 3
Content
1Safety 7
Electrical Hazards 8
Warning 9
Caution 9
Note 9
Information Symbols 10
2 Introduction 11
Serial Number Format 13
3 Setting Up the 850-DS 15
Initial Setup 16
Equipment Ratings / Environmental Requirements for Installation 17
Specification 18
Equipment, Parts, and Accessories As Shipped 19
Parts and Accessories 19
Connections 20
Tubing 21
Power Cord 22
Apparatus Control Cable 22
Synchronized Start 23
Initial Power Up 24
Sample Tray Installation 24
Updating 850-DS Language Screens 25

Content
4850-DSOperator’sManual
Optional Filter Module 27
Changing Trays / Needle Replacement 28
4 Operating the 850-DS 29
Startup Screen 30
Main Screen 32
Menu Screens 36
Methods 36
Method Properties (Apparatus 1/2/5/6) 38
Sample Collection Parameters (Apparatus 1/2/5/6) 40
Method Properties (Apparatus 3/7) 43
Timepoint Number Selection 46
Timepoint Parameter Entry (Apparatus 1/2/5/6) 47
Timepoint Parameter Entry (Apparatus 3/7) 48
Run Method Screen 1 49
Run Method Screen 2 50
Run Method Screen 3 52
Run Method Screen 4 53
Run Method Screen 5 53
850-DS Method Transfer (to another 850-DS) 54
Alarms 56
Calibration 57
Cleaning 61
Diagnostics 64
Diagnostics Screen 2 66
Diagnostics Screen 3 67
Diagnostic Screen 4 (Apparatus 1/2/5/6) 69
Diagnostic Screen 4 (Apparatus 3/7) 71
Instrument Settings 72
Instrument Settings Screen 2 74
Manufacturing Configuration 78
Reports 79
User Access 80

Content
850-DS Operator’s Manual 5
Dialog Screens (Blue) 83
Warning Screens (Yellow) 85
Error Screens (Red) 88
5 Maintenance and Troubleshooting 91
Preventive Maintenance 92
Clean System 92
Periodic Maintenance 92
Printer Maintenance 93
Removing a Thermal Paper Roll 93
Inserting a Thermal Paper Roll 95
Thermal Printer Test 98
Obtaining Warranty and Other Services 99

Content
6850-DSOperator’sManual
This page was intentionally left blank, except for this message.

850-DS Operator’s Manual 7
1Safety
Electrical Hazards 8

1Safety
8850-DSOperator’sManual
The Agilent 850-DS Dissolution Sampling Station has been designed and tested
so that when used properly you have an accurate, fast, flexible, and safe
instrument.
If the equipment is used in a manner not specified by the manufacturer, the
protection provided by the equipment may be impaired.
Operation of a Agilent 850-DS involves the use of aqueous liquids and various
pharmaceutical dosage forms. Unskilled, improper, or careless use of this
instrument can create shock hazards, fire hazards, or other hazards which can
cause death, serious injury to personnel, or severe damage to equipment and
property.
Information on safety practices is provided with your instrument and operation
manuals. Before using your instrument or accessories, you must thoroughly read
these safety practices.
Observe all relevant safety practices at all times.
Electrical Hazards
The dissolution apparatus contains electrical circuits, devices, and components
operating at dangerous voltages. Contact with these circuits, devices, and
components can cause death, serious injury, or painful electric shock.
Panels or covers that are retained by fasteners which require the use of a tool for
removal may be opened only by Agilent-trained, Agilent-qualified, or
Agilent-authorized service engineers. Consult the manuals or product labels
supplied with the dissolution apparatus to determine which parts are
operator-accessible.
Application of the wrong supply voltage, connection of the instrument to an
incorrectly wired supply outlet, or lack of proper electrical grounding can create a
fire hazard or a potentially serious shock hazard and could seriously damage the
instrument and any attached ancillary equipment.
Always use a three-wire outlet with ground connection which is adequately rated
for the load. The installation must comply with local, state, and federal safety
regulations.
Do not connect the instrument to the main power supply until you have made
sure that the operating voltage is correctly set for the main power supply in the
specific outlet in your laboratory to which the equipment will be connected.

1Safety
850-DS Operator’s Manual 9
Warning
WARNING
A ‘Warning’ message appears in the manual when failure to observe instructions
or precautions could result in death or injury.
Read all warnings and cautions carefully and observe them at all times.
Caution
CAUTION
A ‘Caution’ message appears in the manual when failure to observe instructions
could result in damage to equipment (Agilent supplied and / or other associated
equipment).
Note
NOTE
A ‘Note’ appears in the manual to give advice or information.

1Safety
10 850-DS Operator’s Manual
Information Symbols
A depressed power button in the front of the
unit (with green light) indicates main power
on.
An extended power button in the front of the
unit (with green light off) indicates main
power off.
Indicates single-phase alternating current
Indicates the product complies with the
requirements of one or more European Union
(EU) directives.
Indicates specific equipment meets
standards of safety. These products are safe
for use in the workplace for North America.
Indicates that this product must not be
disposed of as unsorted municipal waste.
All Agilent products that are subject to the
WEEE directive shipped after August 13,
2005 are compliant with the WEEE marking
requirements. Such products are marked
with the “crossed out wheelie bin” WEEE
symbol in accordance with European
Standard EN 50419.
For more information on collection, reuse,
and recycling systems, please contact your
local/regional waste administration, your
local distributor, or Agilent.
Indicates the product complies with
regulatory compliance requirements of New
Zealand and Australia.