Metrohm 761 Compact IC User manual

761 Compact IC
METROHM Ltd.
CH-9101 Herisau
Switzerland
Phone ++41 71 353 85 85
Fax ++41 71 353 89 01
8.761.1063
Instructions for Use

CH-9101 Herisau/Switzerland
Phone ++41 71 353 85 85
Fax ++41 71 353 89 01
Internet www.metrohm.ch
E-Mail [email protected]
761 Compact IC
Program «761 PC Software 1.1»
8.761.1063 Instructions for Use
07.07.2004 / chs

Table of contents
761 Compact IC I
Table of contents
1 Introduction............................................................................................................1
1.1 Instrument description .......................................................................................... 1
1.2 Parts and controls .................................................................................................. 3
1.3 Information on the Instructions for Use ...........................................................10
1.3.1 Organization ......................................................................................... 10
1.3.2 Notation and pictograms...................................................................... 11
1.4 Safety notes...........................................................................................................12
1.4.1 Electrical safety..................................................................................... 12
1.4.2 General precautionary rules ................................................................. 12
2 Installation .......................................................................................................... 13
2.1 Overview ................................................................................................................ 13
2.1.1 Flow chart ............................................................................................. 13
2.1.2 Connections in the 761 Compact IC .................................................... 13
2.2 Setting up the instrument....................................................................................15
2.2.1 Packaging............................................................................................. 15
2.2.2 Check.................................................................................................... 15
2.2.3 Location ................................................................................................ 15
2.3 Attaching the accessories ..................................................................................15
2.3.1 Connection of detector block ............................................................... 15
2.3.2 Connection of syringe and aspirating tubing....................................... 16
2.3.3 Connection of the drain tube for the inner compartment..................... 16
2.3.4 Connection of the drain tube for bottle rack ........................................ 17
2.3.5 Connection of PEEK capillaries............................................................ 17
2.3.6 Filter unit PEEK ..................................................................................... 18
2.4 Mains connection .................................................................................................19
2.4.1 Setting the mains voltage ..................................................................... 19
2.4.2 Fuses .................................................................................................... 20
2.4.3 Mains cable and mains connection ..................................................... 20
2.4.4 On/off switching of the instrument ....................................................... 20
2.5 Connection to the PC........................................................................................... 21
2.5.1 Connecting cable ................................................................................. 21
2.5.2 Software installation.............................................................................. 21
2.5.3 Basic settings ....................................................................................... 22
2.6 High-pressure pump ............................................................................................25
2.6.1 Removing the transport security screws .............................................. 25
2.6.2 Installing the pulsation dampener ........................................................ 25
2.6.3 Connecting the eluent bottle ................................................................ 27
2.6.4 Deaerating the pump and rinsing the pulsation dampener................. 29
2.7 Precolumns and separating columns ............................................................... 31
2.7.1 General information on precolumns..................................................... 31
2.7.2 Precolumns with cartridge head........................................................... 31
2.7.3 Precolumn glass cartridges with cartridge holder ............................... 33
2.7.4 IC anion precolumn SUPERSEP .......................................................... 34
2.7.5 General information on separating columns........................................ 35
2.7.6 Selection of the sample loop................................................................ 35
2.7.7 Installation of the separating column without suppressor ................... 36
2.7.8 Installation of the separating column with suppressor ........................ 37

Table of contents
761 Compact IC
II
2.8 Suppressor module ............................................................................................. 38
2.8.1 General information on suppressor module ........................................ 38
2.8.2 Preparation of the peristaltic pump...................................................... 38
2.8.3 Connection of supply bottles ............................................................... 41
2.8.4 Connection of the suppressor module ................................................ 43
2.9 Putting into operation.......................................................................................... 45
2.9.1 Putting into operation without suppressor ........................................... 45
2.9.2 Putting into operation with suppressor ................................................ 46
2.10 Connection of external devices ......................................................................... 49
2.10.1 Connection of the 750 Autosampler .................................................... 49
2.10.2 Connection of the 766 IC Sample Processor ...................................... 50
2.10.3 Connection of other devices ................................................................ 52
3 Operating tutorial ....................................................................................... 53
3.1 Requirements........................................................................................................ 53
3.2 Preparations.......................................................................................................... 54
3.3 Calibration ............................................................................................................. 55
3.4 Sample determination ......................................................................................... 63
4 Operation............................................................................................................... 67
4.1 Fundamentals of the operation.......................................................................... 67
4.1.1 Starting/closing the program ............................................................... 67
4.1.2 Glossary................................................................................................ 68
4.1.3 Overview of program windows............................................................. 69
4.1.4 Main window elements......................................................................... 70
4.1.5 Icons of the main window..................................................................... 70
4.1.6 Overview of file types............................................................................ 71
4.1.7 Context sensitive menus ...................................................................... 72
4.1.8 Keyboard and mouse functions........................................................... 72
4.1.9 Help ...................................................................................................... 73
4.2 Instrument and software settings...................................................................... 74
4.2.1 Fonts..................................................................................................... 74
4.2.2 Security system .................................................................................... 74
4.2.3 Global settings ..................................................................................... 75
4.2.4 COM port .............................................................................................. 77
4.3 Systems ................................................................................................................. 78
4.3.1 System window .................................................................................... 78
4.3.2 System file handling ............................................................................. 78
4.3.3 System functions .................................................................................. 79
Connect and disconnect system ................................................. 79
Start/stop hardware and record baseline .................................... 79
Start/stop determinations............................................................. 80
Options for determinations........................................................... 80
4.3.4 System settings .................................................................................... 82
Modify system window ................................................................. 82
Watch window display.................................................................. 82
Set start mode .............................................................................. 82
Print system parameters .............................................................. 83
4.3.5 PC icon ................................................................................................. 83

Table of contents
761 Compact IC III
Menu options for PC icon............................................................. 83
Select processing method and data source................................ 83
4.3.6 Watch window....................................................................................... 84
Menu options for screen icon....................................................... 84
4.3.7 Instrument icon ..................................................................................... 85
Menu options for instrument icon................................................. 85
System parameters for disconnected system ............................. 85
Instrument control for connected system .................................... 86
Time program ............................................................................... 88
Configuration ................................................................................ 90
Hardware settings ........................................................................ 91
4.3.8 Timer ..................................................................................................... 94
4.3.9 System state window............................................................................ 95
Status messages.......................................................................... 95
Error messages ............................................................................ 96
4.4 Methods ................................................................................................................. 97
4.4.1 Method file handling ............................................................................. 97
4.4.2 Passport................................................................................................ 97
General ......................................................................................... 98
Sample.......................................................................................... 99
Column ....................................................................................... 100
Eluent .......................................................................................... 101
Comment .................................................................................... 101
Method Log ................................................................................ 102
Data Log ..................................................................................... 103
4.4.3 Method setup...................................................................................... 104
General ....................................................................................... 104
Measure ...................................................................................... 104
Filters .......................................................................................... 105
Processing.................................................................................. 106
Math ............................................................................................ 107
4.4.4 Integration........................................................................................... 109
Setup........................................................................................... 110
Events ......................................................................................... 112
4.4.5 Calibration and quantification............................................................. 117
General information .................................................................... 117
Notations..................................................................................... 118
External standard calibration...................................................... 119
Component table........................................................................ 119
Peak identification ...................................................................... 121
Concentration table .................................................................... 123
Calibration curve......................................................................... 125
Update calibration ...................................................................... 127
Load and save calibration data.................................................. 128
Import and export calibration data ............................................. 128
Put out calibration curves ........................................................... 128
4.4.6 Report output...................................................................................... 129
Report options ............................................................................ 129
4.5 Chromatograms..................................................................................................141
4.5.1 Chromatogram window ...................................................................... 141
4.5.2 Chromatogram file handling............................................................... 142
Open chromatogram.................................................................. 142
Save chromatogram................................................................... 143
Close chromatogram.................................................................. 143
Delete chromatogram................................................................. 143
Export chromatogram................................................................. 143
Import chromatogram ................................................................ 144
4.5.3 Graphical representation .................................................................... 145

Table of contents
761 Compact IC
IV
Appearance ................................................................................ 145
Other graphical functions........................................................... 149
4.5.4 Peak editor.......................................................................................... 150
Switching on/off the peak editor ................................................ 150
Peak editor functions.................................................................. 150
Moving the cursor....................................................................... 151
4.5.5 Printing................................................................................................ 152
Page layout for printing .............................................................. 152
Printer settings............................................................................ 153
Print preview ............................................................................... 153
Printing........................................................................................ 153
4.5.6 Miscellaneous functions..................................................................... 153
Reintegration .............................................................................. 153
Recalibration............................................................................... 153
Subtraction of a chromatogram................................................. 154
Data compression ...................................................................... 154
Invert chromatogram.................................................................. 154
Autodatabase options................................................................ 155
Indicate active Autodatabase program ..................................... 155
4.6 Sample queue ..................................................................................................... 156
4.6.1 Sample queue file handling................................................................ 156
Open sample queue................................................................... 156
Save sample queue.................................................................... 156
Delete sample queue ................................................................. 156
4.6.2 Sample queue control ........................................................................ 157
Sample queue overview table .................................................... 157
Start sample queue .................................................................... 158
Pause sample queue ................................................................. 159
Cancel last run............................................................................ 159
Reset sample queue .................................................................. 159
4.6.3 Sample queue editor .......................................................................... 159
Open queue editor window........................................................ 159
Sample queue editor functions .................................................. 161
Print sample queue .................................................................... 161
Close sample queue editor ........................................................ 161
4.7 Batch reprocessing............................................................................................ 162
4.7.1 Batch reprocessing queue file handling ............................................ 162
Open batch reprocessing queue ............................................... 162
Create new batch reprocessing queue...................................... 162
Save batch reprocessing queue ................................................ 162
4.7.2 Perform batch reprocessing............................................................... 163
Reprocess options window........................................................ 163
Merge chromatograms .............................................................. 166
4.7.3 Batch reprocessing queue editor....................................................... 167
Open batch reprocessing queue editor window ....................... 167
Batch reprocessing queue editor functions............................... 168
Print batch reprocessing queue................................................. 168
Close batch reprocessing queue editor .................................... 168

Table of contents
761 Compact IC V
5 Notes – Maintenance – Faults....................................................169
5.1 Practical notes on ion chromatography .........................................................169
5.1.1 Separating columns............................................................................ 169
5.1.2 High-pressure pump .......................................................................... 170
5.1.3 Eluents ................................................................................................ 171
5.1.4 Peristaltic pump.................................................................................. 171
5.1.5 Suppressor module ............................................................................ 172
5.1.6 Connections........................................................................................ 172
5.2 Maintenance and servicing...............................................................................173
5.2.1 General information ............................................................................ 173
5.2.2 Passivation.......................................................................................... 173
5.2.3 Recycling ............................................................................................ 174
5.2.4 Shutdown............................................................................................ 174
5.2.5 Changing separating columns ........................................................... 174
5.2.6 Maintenance work at the pump head ................................................ 176
5.2.7 Regeneration of the suppressor module ........................................... 180
5.2.8 Cleaning the suppressor .................................................................... 181
5.2.9 Replacing the suppressor .................................................................. 183
5.2.10 Exchanging the pump tubing ............................................................. 185
5.3 Faults and malfunctions ....................................................................................186
5.3.1 Error messages .................................................................................. 186
5.3.2 Malfunctions and their rectification..................................................... 186
5.4 Diagnostic tests / Validation / GLP..................................................................188
6 Appendix..............................................................................................................189
6.1 Technical data.....................................................................................................189
6.1.1 Conductivity measurement................................................................. 189
6.1.2 Conductivity detector.......................................................................... 189
6.1.3 Injection valve ..................................................................................... 190
6.1.4 High-pressure pump .......................................................................... 190
6.1.5 Peristaltic pump.................................................................................. 191
6.1.6 Suppressor module ............................................................................ 191
6.1.7 Leak detector ...................................................................................... 191
6.1.8 RS232 interface .................................................................................. 191
6.1.9 Remote interface................................................................................. 192
6.1.10 Analog output ..................................................................................... 192
6.1.11 Mains connection ............................................................................... 192
6.1.12 Safety specifications........................................................................... 192
6.1.13 Electromagnetic compatibility (EMC)................................................. 193
6.1.14 Ambient temperature.......................................................................... 193
6.1.15 Housing............................................................................................... 193
6.2 Standard equipment...........................................................................................194
6.3 Optional accessories .........................................................................................198
6.3.1 Accessories for capillary connections................................................ 198
6.3.2 High-pressure pump .......................................................................... 199
6.3.3 Separating columns and precolumns................................................ 200
6.3.4 Additional devices and cables ........................................................... 205
6.4 Warranty and conformity...................................................................................206
6.4.1 Warranty.............................................................................................. 206
6.4.2 EU Declaration of conformity.............................................................. 207
6.4.3 Certificate of conformity and system validation ................................. 208
6.5 Index .....................................................................................................................209

Table of contents
761 Compact IC
VI
List of figures
Fig. 1: Front of the 761 Compact IC .......................................................................... 3
Fig. 2: Rear of the 761 Compact IC........................................................................... 4
Fig. 3: Interior of the 2.761.0010 Compact IC ........................................................... 6
Fig. 4: Interior of the 2.761.0020 Compact IC ........................................................... 8
Fig. 5: Connecting diagram for 2.761.0010 Compact IC without suppressor........ 14
Fig. 6: Connecting diagram for 2.761.0020 Compact IC with suppressor............. 14
Fig. 7: Connectors for capillaries............................................................................. 17
Fig. 8: 6.2821.000 Filter unit PEEK .......................................................................... 18
Fig. 9: Setting the mains voltage ............................................................................. 20
Fig. 10: Connection of the pulsation dampener........................................................ 26
Fig. 11: Connection of eluent bottle........................................................................... 28
Fig. 12: Installation of precolumn cartridges with cartridge head............................. 32
Fig. 13: Installation of precolumn glass cartridges with cartridge holder ................. 34
Fig. 14: Installation of column without suppressor.................................................... 37
Fig. 15: Installing pump tubings ................................................................................ 39
Fig. 16: Connection of the separating column with suppressor ............................... 40
Fig. 17: Connection of supply bottles........................................................................ 42
Fig. 18: Connections at suppressor module ............................................................. 43
Fig. 19: Components of the pump head ................................................................. 177
Fig. 20: Replacement of the piston seal 112 .......................................................... 177
Fig. 21: Components of inlet valve 113 and outlet valve 114................................. 179
Fig. 22: Assembling the suppressor........................................................................ 183

Table of contents
761 Compact IC VII
List of numbered parts and controls
1Door to interior .................................3,7,9
2Connection for syringe...........................3
3Feedthrough for aspirating tubing.........3
4Aspirating tubing..............................3,7,9
5Feedthrough for capillaries....................3
6Connection for drain tube .....................3
7Feedthrough for capillaries....................3
8Connection to purge valve .................... 3
9Mains pilot lamp.....................................3
10 Bottle rack ...........................................3,5
11 Opening for detector cable....................5
12 Opening for inlet capillaries ...................5
13 Opening for outlet capillaries.................5
14 Connection for drain tube ......................5
15 Knurled screw ........................................5
16 Rear panel opening ...............................5
17 Detachable rear panel ...........................5
18 Transport security screws......................5
19 Mains switch .....................................5,20
20 Mains connection plug .....................5,20
21 Fuse holder .......................................5,20
22 RS232 interface......................................5
23 Connection for detector block ...............5
24 Remote interface....................................5
25 Serial number.........................................5
26 Inlet capillary for injector ................7,9,26
27 Mounting rail .............................7,9,37,40
28 Column connection
capillary ...........................7,9,32,34,37,40
29 Sample loop........................................7,9
30 Connection capillary to syringe ..........7,9
31 Rotary nipple for aspirating tube ........7,9
32 Injection valve.......................7,9,26,37,40
33 PEEK coupling ...............................7,9,40
34 Leak detector ......................................7,9
35 Connection capillary .....................7,9,26
36 Filter unit PEEK ....................7,9,18,26,40
37 Connection capillary ......................7,9,26
38 Connection capillary ...........................7,9
39 Purge valve.....................................7,9,26
40 Aspirating capillary..............................7,9
41 Fastening screws ................................7,9
42 Pump head...................................7,9,177
43 Connection capillary............................7,9
44 Connection capillary............................7,9
45 Inlet capillary for
detector block .......................... 7,9,37,40
46 Detector block .......................... 7,9,37,40
47 Suppressor module...........................9,40
48 Tubing cartridge ...........................9,39,41
49 Contact pressure lever .................9,39,41
50 Holding clamp...................................9,41
51 Snap-action lever .........................9,39,41
52 Pump drive ........................................9,41
53 Mounting pin .....................................9,41
54 Compression fitting .... 17,18,32,34,39,42
55 Compression fitting ..............................17
56 Capillary..................................... 17,18,34
57 Filter-Screw of Filter Unit .................18,39
58 Filter .................................................18,39
59 Filter-Housing of Filter Unit ..................18
60 Pulsation dampener .............................26
61 Connection to injection valve ...............26
62 Connection to purge valve ...................26
63 Aspirating tubing ..................................28
64 Tubing nipple........................................28
65 Threaded stopper.................................28
66 Bottle attachment .................................28
67 Eluent bottle..........................................28
68 Aspirating filter......................................28
69 CO2absorber .......................................28
70 Cotton wool ..........................................28
71 SGJ clip ................................................28
72 Absorber tube.......................................28
73 Manufit housing....................................32
74 Steel connector ....................................32
75 PTFE gasket .........................................32
76 2 Steel meshes.....................................32
77 Precolumn cartridge.............................32
78 Steel spacer .........................................32

Table of contents
761 Compact IC
VIII
79 4 Steel meshes .................................... 32
80 Manufit pressure screw ....................... 32
81 Separating column .................... 32,37,40
82 End fitting............................................. 34
83 Screw cap for precolumn .................... 34
84 Sleeve for precolumn cartridge ........... 34
85 Precolumn cartridge ............................ 34
86 Connection piece................................. 34
87 Screw cap for column.......................... 34
88 Column holder ................................ 37,40
89 Aspirating tubing for H2O........... 39,40,42
90 Aspirating tubing for H2SO4....... 39,40,42
91 Coupling ......................................... 39,40
92 Pump tubing for H2SO4................... 39,40
93 Pump tubing for H2O ...................... 39,40
94 Stopper ................................................ 39
95 PTFE tubing .................................... 39,40
96 Suppressor inlet capillary
for eluent ......................................... 41,43
97 Suppressor outlet capillary
for eluent ......................................... 41,43
98 Suppressor inlet capillary
for H2O ............................................ 41,43
99 Suppressor inlet capillary
for H2SO4.................................... 39,41,43
100 Suppressor outlet capillary
for H2O ............................................ 41,43
101 Suppressor outlet capillary
for H2SO4......................................... 41,43
102 Bottle attachment.................................42
103 Supply bottle ........................................42
104 Screw..................................................177
105 Zircon piston ......................................177
106 Spring retainer....................................177
107 Spring.................................................177
108 Piston cartridge..................................177
109 Piston guide sleeve............................177
110 Sapphire supporting ring ...................177
111 Piston guide sleeve............................177
112 Piston seal..........................................177
113 Inlet valve ....................................177,179
114 Outlet valve..................................177,179
115 Screw holder ......................................177
116 Special tool ........................................177
117 Special tool ........................................177
118 Valve housing.....................................179
119 Sealing ring ........................................179
120 Sleeve.................................................179
121 Sapphire sleeve .................................179
122 Sapphire sphere.................................179
123 Ceramic holder...................................179
124 Seal ....................................................179
125 Screw nut ...........................................183
126 Connection piece...............................183
127 Suppressor rotor ................................183
128 Suppressor holder .............................183

1.1 Instrument description
761 Compact IC 1
1 Introduction
1.1 Instrument description
The 761 Compact IC is a PC-controlled system for ion chroma-
tographic analyses. The two following versions are available:
• 2.761.0010 Compact IC without suppressor module
• 2.761.0020 Compact IC with suppressor module
The extremely compact housing of the 761 Compact IC contains every-
thing needed to carry out ion chromatography at the highest quality
level:
• Injection valve – for individual injections or for use with a sample
changer such as the Metrohm 766 IC Sample Processor
• High-pressure pump – extremely low-pulsation double piston
pump with a flow range from 0.2 …2.5 mL/min and a maximum
pressure of 25 MPa (250 bar)
• Pulsation dampener – even with low-level pressure variations the
pulsation dampener reliably protects the column against damage
• Column chamber – the perfect insulation of the housing provides
not only thermally stable conditions for the separation column but
also shields the system against electromagnetic interference
• Columns – whether anion columns with or without suppression,
separation columns for cations or organic acids – the 761 Compact
IC can accommodate them all
• Suppressor – the Metrohm Suppressor Module (MSM) is already
integrated in the 2.761.0020 Compact IC – pressure-resistant, with
fully automatic regeneration, highest performance and optimal re-
producibility
• Peristaltic pump – integrated two-channel peristaltic pump with a
flow rate of 0.5 …0.6 mL/min for regeneration and rinsing of the
suppressor module built into the 2.761.0020 Compact IC
• Detector – conductivity detector with outstanding temperature
stability. The detector temperature varies by less than 0.01°C and
can be optimally adapted to the ambient conditions.
All components which come into contact with eluent and sample are
metal-free.

1 Introduction
761 Compact IC
2
The operation of the 761 Compact IC takes place via a PC connected
to the RS232 interface with the help of the control and evaluation pro-
gram «761 Compact IC». This PC program can be used to create sys-
tems for recording and evaluating chromatograms. Time programs can
also be created in which a large number of instrument functions can be
triggered for each program step. It is also possible to use programma-
ble signals to control external instruments such as the 750 Autosampler
or the 766 IC Sample Processor via the remote interface.
About 80 prepared system configurations for more than 300 applica-
tions are already permanently stored and additional new applications
can be downloaded at any time from the Internet under
«www.metrohm.ch».
The operating software for the 761 Compact IC meets all the require-
ments you could place today on a modern integration software: single
or multi-point calibration, internal or external standard, selectable algo-
rithms for non-linear calibration, various integration modes with integra-
tion parameters and integration events, different methods for peak rec-
ognition, peak editor, free scaling, superimposing several
chromatograms, use of sample tables and batch reprocessing; a pow-
erful and GLP-conform report generator with output interfaces for moni-
tor, printer and external databases.
The independent «Autodatabase»PC programm supplied can be used
to save and handle results and chromatograms produced by the «761
Compact IC»program in a database. With «Autodatabase», data can
be sorted, filtered and searched with the help of different criteria. In ad-
dition, data and curves can be printed out according to user-defined
report templates.

1.2 Parts and controls
761 Compact IC 3
1.2 Parts and controls
POWER
761 Compact IC
89 76 5
2
3
4
1
10
Fig. 1: Front of the 761 Compact IC
1Door to interior 6 Connection for drain tube
for discharge of spilled liquid from the
interior
2Connection for 6.2816.020 Syringe
for aspiration of the sample
7 Feedthrough for capillaries
3Feedthrough for aspirating tubing 8Connection to purge valve
4Aspirating tubing
for sample
9Mains pilot lamp
lit up when instrument switched on
5Feedthrough for capillaries 10 Bottle rack
for holding supply bottles with eluent,
regeneration solution, and rinsing
solution

1 Introduction
761 Compact IC
4
WARNING - Fire Hazard -
with the same type and rating of fuse
For continued protection replace only
Type 1.761.
Fuse
100-120V:
220-240V:
1,0A(T)
0,5A(T)
Made by Metrohm Herisau Switzerland
RS 232
Detector Block
Remote
Waste B Waste A
Transport security screws
17
18
19
20
21
11 13 14 13 10
23a
22
15
25
24
12 12 11
15
16
15 15
f = 50-60 Hz
S = 100 VA
Analog Output
23
Fig. 2: Rear of the 761 Compact IC

1.2 Parts and controls
761 Compact IC 5
10 Bottle rack
for holding supply bottles with eluent,
regeneration solution, and rinsing
solution
18 Transport security screws
to secure the pump head when the
instrument is transported
11 Opening for detector cable 19 Mains switch
to switch instrument on and off:
I = ON 0 = OFF
12 Opening for inlet capillaries
for supply of eluent, regeneration
solution, and rinsing solution into the
inner compartment
20 Mains connection plug
mains connection, see section 2.4
13 Opening for outlet capillaries
for discharge of eluent, regeneration
solution, and rinsing solution from the
inner compartment
21 Fuse holder
changing the fuses, see section 2.4
14 Connection for drain tube
for discharge of spilled liquid from the
bottle rack
22 RS232 interface
connection of the PC
15 Knurled screw
for fastening the rear panel 17
23
23a
Connection for detector block
Analog output for measuring
signal
16 Rear panel opening
(closed with plastic stopper) for
additional supply and discharge lines to
and from the inner compartment
24 Remote interface
remote I/O lines for connection of
external devices
17 Detachable rear panel
access to upper part of inner
compartment
25 Serial number

1 Introduction
761 Compact IC
6
37
44
1
26
27
27
28
29
30
31
32
43
42
41
40
39
38
36 35 34
4
33
45
46
Fig. 3: Interior of the 2.761.0010 Compact IC
(with permanently attached accessories and
1.733.0110 Detector block)

1.2 Parts and controls
761 Compact IC 7
1Door to interior 36 Filter unit PEEK (6.2821.120)
4Aspirating tubing
for aspirating the sample;
6.1803.020 PTFE tubing,
length L= 52 cm
37 Connection capillary
6.1831.010 PEEK capillary,
length L= 13 cm
26 Inlet capillary for injector
6.1831.010 PEEK capillary,
length L= 24 cm
38 Connection capillary
6.1831.010 PEEK capillary,
length L= 15 cm
27 Mounting rail
for 6.2027.0X0 column holder
39 Purge valve
28 Column connection capillary
6.1831.010 PEEK capillary,
length L= 30 cm
40 Aspirating capillary
Connection for 6.1834.010 aspirating
tubing
29 Sample loop 10 µL
6.1825.230 PEEK sample loop
41 Fastening screws
for pump head 42
30 Connection capillary to syringe
6.1803.020 PTFE tubing,
length L= 30 cm
42 Pump head (6.2824.100)
31 Rotary nipple for aspirating tube
for fixing the aspirating tube
43 Connection capillary
Connection pump head – purge
valve, fixed mounting
32 Injection valve 44 Connection capillary
in pump head, fixed mounting
33 PEEK coupling (6.2744.040) 45 Inlet capillary for detector block
PEEK capillary, fixed mounting
34 Leak detector 46 Detector block (1.732.0110)
35 Connection capillary
6.1831.010 PEEK capillary,
length L= 13 cm

1 Introduction
761 Compact IC
8
37
44
1
26
27
27
28
29
30
31
32
43
42
41
40
39
38
36 35 34
4
33
45
46
47
48
49
53 52 5051
Fig. 4: Interior of the 2.761.0020 Compact IC
(with permanently attached accessories and
1.733.0110 Detector block)

1.2 Parts and controls
761 Compact IC 9
1Door to interior 39 Purge valve
4Aspirating tubing
for aspirating the sample;
6.1803.020 PTFE tubing,
length L= 52 cm
40 Aspirating capillary
Connection for 6.1834.010 aspirating
tubing
26 Inlet capillary for injector
6.1831.010 PEEK capillary,
length L= 24 cm
41 Fastening screws
for pump head 42
27 Mounting rail
for 6.2027.0X0 column holder
42 Pump head (6.2824.100)
28 Column connection capillary
6.1831.010 PEEK capillary,
length L= 30 cm
43 Connection capillary
Connection pump head – purge
valve, fixed mounting
29 Sample loop 20 µL
6.1825.210 PEEK sample loop
44 Connection capillary
in pump head, fixed mounting
30 Connection capillary to syringe
6.1803.020 PTFE tubing,
length L= 30 cm
45 Inlet capillary for detector block
PEEK capillary, fixed mounting
31 Rotary nipple for aspirating tube
for fixing the aspirating tube
46 Detector block (1.732.0110)
32 Injection valve 47 Suppressor module
(inlet and outlet capillaries are not
shown)
33 PEEK coupling (6.2744.040) 48 Tubing cartridge (6.2755.000)
for 6.1826.060 pump tubing
34 Leak detector 49 Contact pressure lever
for adjusting the contact pressure
35 Connection capillary
6.1831.010 PEEK capillary,
length L= 13 cm
50 Holding clamp
for locking the tubing cartridge into
place
36 Filter unit PEEK (6.2821.120) 51 Snap-action lever
for releasing the tubing cartridge
37 Connection capillary
6.1831.010 PEEK capillary,
length L= 13 cm
52 Pump drive
roller head with contact rollers
38 Connection capillary
6.1831.030 PEEK capillary,
length L= 20 cm
53 Mounting pin
for attaching the tubing cartridges

1 Introduction
761 Compact IC
10
1.3 Information on the Instructions for Use
Please read through these Instructions for Use carefully before you put
the 761 Compact IC into operation. The Instructions for Use contain
information and warnings to which the user must pay attention in order
to assure safe operation of the instrument.
1.3.1 Organization
These 8.761.1063 Instructions for Use for the 761 Compact IC pro-
vide a comprehensive overview of the installation, startup procedure,
operation, fault rectification and technical specifications of this instru-
ment. The Instructions for Use are organized as follows:
Section 1 Introduction
General description of instrument, parts and controls
and safety notes
Section 2 Installation
Installation of instrument, accessories,
and external devices
Section 3 Operating tutorial
Introduction to the operation using an example
Section 4 Operation
Detailed description of the operation
Section 5 Notes – Maintenance – Faults
Notes on ion chromatography, maintenance, fault rectifi-
cation, diagnostic tests, validation
Section 6 Appendix
Technical data, standard equipment, options, warranty,
declarations of conformity, index
To find the required information on the instruments, you will find it an
advantage to use either the Table of contents or the Index at the
back.
As a supplement to the Instructions for Use, the Metrohm Monograph
8.732.2003 "Ion chromatography" is also supplied. This provides an
introduction to the theoretical fundamentals and general information on
separating columns and sample pretreatment.
The 8.732.2013 IC Applications Collection is also supplied; this con-
tains all the Application Notes on the subject of ion chromatography.
Each of these applications can be carried out directly with the 761
Compact IC by loading the system file with the same name. The Appli-
cations Collection can be updated at any time by downloading the lat-
est applications from the Internet under «www.metrohm.ch».
You will find detailed information on the separating columns available
from Metrohm and on special IC applications in the relevant "Applica-
tion Bulletins", which are available on request free of charge from your
Metrohm agency.