AB Sciex 4500 Series User manual

AB SCIEX 4500 Series of Instruments
System User Guide
Document Number: D5030863 A
Release Date: March 2012

AB SCIEX
71 Four Valley Dr., Concord, Ontario, Canada. L4K 4V8.
AB Sciex LP is ISO 9001 registered.
© 2012 AB SCIEX.
Printed in Canada.
This document is provided to customers who have purchased
AB Sciex equipment to use in the operation of such AB Sciex
equipment. This document is copyright protected and any reproduction
of this document or any part of this document is strictly prohibited,
except as AB Sciex may authorize in writing.
Software that may be described in this document is furnished under a
license agreement. It is against the law to copy, modify, or distribute
the software on any medium, except as specifically allowed in the
license agreement. Furthermore, the license agreement may prohibit
the software from being disassembled, reverse engineered, or
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Portions of this document may make reference to other manufacturers
and/or their products, which may contain parts whose names are
registered as trademarks and/or function as trademarks of their
respective owners. Any such use is intended only to designate those
manufacturers' products as supplied by AB Sciex for incorporation into
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as trademarks.
AB Sciex makes no warranties or representations as to the fitness of
this equipment for any particular purpose and assumes no
responsibility or contingent liability, including indirect or consequential
damages, for any use to which the purchaser may put the equipment
described herein, or for any adverse circumstances arising therefrom.
For research use only. Not for use in diagnostic procedures.
The trademarks mentioned herein are the property of
AB Sciex Pte. Ltd. or their respective owners.
AB SCIEX™ is being used under license.

System User Guide
Document Number: D5030863 A
4500 Series of Instruments
3 of 142
Contents
Chapter 1 Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
General Safety Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7
Symbols and Conventions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7
Qualified Personnel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8
Equipment Use and Modification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8
Shipping Labels . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9
Regulatory Compliance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9
Australia and New Zealand . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9
Canada . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9
Europe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10
United States . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10
International . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10
Symbols and Labels on the Mass Spectrometer . . . . . . . . . . . . . . . . . . . . . . . . .10
Occupational Health and Safety Symbols . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12
Mains Supply . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14
Laboratory Ventilation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14
Environmental Conditions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14
Instrument Disposal (Waste Electrical and Electronic Equipment) . . . . . . . . . . .15
Chapter 2 System Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
Theory of Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17
Data Handling . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17
System Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17
Instrument Panel Symbols . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20
Turn on the System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20
Reset the System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
Shut Down the System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
Edit the Hardware Profile for the Integrated Syringe Pump . . . . . . . . . . . . . . . .22
Adjust the Integrated Syringe Pump Position . . . . . . . . . . . . . . . . . . . . . . . . . . .22
Configure the Integrated Syringe Pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
Configure the Diverter Valve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
Plumb the Diverter Valve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26
Plumb the Diverter Valve in Injector Mode . . . . . . . . . . . . . . . . . . . . . . . . . . .26
Plumb the Diverter Valve in Diverter Mode . . . . . . . . . . . . . . . . . . . . . . . . . . .29
Instrument Safe Fluids . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .30
Chapter 3 Hardware Profiles and Projects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Hardware Profiles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31
Create a Hardware Profile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .31
Add Devices to a Hardware Profile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .34
Troubleshooting Hardware Profile Activation . . . . . . . . . . . . . . . . . . . . . . . . . . .35
Create Projects and Subprojects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .36
Create a Subproject . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37
Copy a Subproject . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37
Installed Project Folders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37

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Back up the API Instrument Folder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .38
Chapter 4 Instrument Tuning and Calibrating. . . . . . . . . . . . . . . . . . . . . . . . . . . 39
Required material . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39
Prerequisites . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39
Optimize the Instrument . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39
Verify or Adjust Performance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .40
Results Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .40
Chapter 5 Basic Acquisition Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
Create Acquisition Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43
Add an Experiment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43
Add a Period . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .43
Copy an Experiment into a Period . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .44
Copy an Experiment within a Period . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .44
Scan Techniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .44
Quadrupole-Mode Scan Types . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .44
LIT-Mode Scan Types . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .45
About Spectral Data Acquisition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .46
Parameters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .46
Acquisition Method Editor Icons . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .53
Chapter 6 Batches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55
Set Queue Options . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .55
Create and Submit a Batch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .56
Change Sample Order . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .58
Acquire Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .58
Set Sample Locations in the Batch Editor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .59
Select Vial Positions using the Locations Tab . . . . . . . . . . . . . . . . . . . . . . . . . .59
Stop Sample Acquisition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .61
Batch and Acquisition Method Editor Tips . . . . . . . . . . . . . . . . . . . . . . . . . . . . .61
Batch Editor Right-Click Menu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62
Queue States and Device Status . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .62
Queue States . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .63
View Instrument and Device Status Icons . . . . . . . . . . . . . . . . . . . . . . . . . . . .64
Queue Right-Click Menu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .65
Chapter 7 Analyzing and Processing Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 69
Open Data Files . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .69
Navigate Between Samples in a Data File . . . . . . . . . . . . . . . . . . . . . . . . . . .69
Show Experimental Conditions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .70
Show Data in Tables . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .70
Show ADC Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .72
Show Basic Quantitative Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .72
Chromatograms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .73
Show TICs from a Spectrum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .73
Show a Spectrum from a TIC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .74
Generate XICs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .74
Generate BPCs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .76
Generate XWCs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .77

Contents
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4500 Series of Instruments
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Show DAD Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .78
Generate TWCs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .78
Adjust the Threshold . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .79
Data Processing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .80
Graphs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .81
Zoom in on the y-axis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .82
Zoom in on the x-axis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .82
Chapter 8 Analyzing and Processing Quantitative Data . . . . . . . . . . . . . . . . . . 85
Quantitative Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .85
Quantitation Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .85
About Results Tables . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .86
Quantitation Methods and Results Tables . . . . . . . . . . . . . . . . . . . . . . . . . . . .86
Create a Method using the Quantitation Method Editor . . . . . . . . . . . . . . . . .86
Create a Results Table using the Quantitation Wizard . . . . . . . . . . . . . . . . . .87
Create a Standard Query . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .88
Results Table Right-Click Menu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .90
Peak Review and Manual Integration of Peaks . . . . . . . . . . . . . . . . . . . . . . . . .91
Review Peaks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .92
Manually Integrate Peaks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .95
Peak Review Right-Click Menu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .96
Calibration Curves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .97
View Calibration Curves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .98
Overlay Calibration Curves . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .99
Calibration Curve Right-Click Menu . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .99
Sample Statistics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .100
View the Statistics for Standards and Qcs . . . . . . . . . . . . . . . . . . . . . . . . . .100
Compare Results Between Batches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .101
Appendix A Turbo V™ Ion Source User Reference . . . . . . . . . . . . . . . . . . . . . .105
Introduction to the Ion Source . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .105
Probes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .106
Gas and Electrical Connections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .108
Ion Source Latch . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .108
Source Exhaust System . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .108
Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .109
Install the Ion Source . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .109
Optimization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .111
Optimize the TurboIonSpray®Probe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .111
Optimize the APCI Probe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .114
Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .116
Clean the Probes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .116
Remove the Ion Source . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .117
Remove the Probe . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .117
Clean the Electrode Tube . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .118
Adjust the Electrode Tip Extension . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .119
Replace the Corona Discharge Needle . . . . . . . . . . . . . . . . . . . . . . . . . . . . .120
Replace the Sample Tubing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .121
Troubleshooting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .122
Consumables . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .123

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Appendix B 4500 Series Instrument Requirements and Parameters . . . . . . . .125
Electrical and Gas Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .125
Instrument Parameters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .125
Appendix C Calibration Ions and Solutions . . . . . . . . . . . . . . . . . . . . . . . . . . . .131
Appendix D Cleaning and Maintenance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .133
Health and Safety Precautions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .133
Surface Cleaning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .134
Empty the Drain Bottle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .134
Front-End Cleaning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .135
Best Practices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .136
Prepare for Routine Cleaning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .137
Clean the Curtain Plate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .138
Clean the Front of the Orifice Plate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .139
Put the Instrument Back into Service . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .139
Appendix E Basic System Troubleshooting . . . . . . . . . . . . . . . . . . . . . . . . . . .141

System User Guide
Document Number: D5030863 A
4500 Series of Instruments
7 of 142
Foreword
This foreword contains general safety-related information, describes the symbols and
conventions used in the documentation, and provides regulatory compliance information. It also
describes potential hazards and associated warnings for the system, and the precautions that
should be taken to minimize the hazards. In addition to this foreword, refer to the Site Planning
Guide for site requirements, including mains supply, source exhaust, ventilation, compressed air,
nitrogen and the roughing pump.
General Safety Information
Before operating any instrument, become familiar with its operation and with the potential
hazards. To prevent personal injury or instrument damage, read, understand, and obey all safety
precautions. Warnings in this document and labels on the mass spectrometer are shown with
international symbols. Failure to heed these warnings could result in serious injury.
This safety information is intended to supplement federal, state or provincial, and local
environmental health and safety (EHS) regulations. The information provided covers instrument-
related safety with regard to the operation of the mass spectrometer. It does not cover every
safety procedure that should be practised. Ultimately, you and your organization are responsible
for compliance with federal, state or provincial, and local EHS regulations and for maintaining a
safe laboratory environment.
For more information, refer to the appropriate laboratory reference material and standard
operating procedures.
Symbols and Conventions
The following conventions are used throughout the guide.
DANGER! Danger signifies an action which leads to severe injury or death.
WARNING! Personal Injury Hazard: A warning indicates an operation that could
cause personal injury if precautions are not followed.
WARNING! Electric Shock Hazard: This symbol indicates a warning of electrical
shock hazard. Read the warning and follow all precautions before performing any
operation described in the guide. Failure to do so can result in serious injury.
WARNING! Burn Hazard: This symbol indicates a warning of potential burns
from hot surfaces. Read the warning and follow all precautions before performing
any operation described in the guide. Failure to do so can result in serious injury.

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Caution: A caution indicates an operation that could cause damage to the instrument or
loss of data if precautions are not followed.
Qualified Personnel
After installing the system, the FSE (Field Service Employee) uses the Customer Familiarization
Checklist to train the customer on system operation, cleaning, and basic maintenance. Only
qualified AB SCIEX personnel shall install and service the equipment. Only personnel qualified
by AB SCIEX shall operate and maintain the equipment. Contact an AB SCIEX FSE for more
information.
Equipment Use and Modification
Use the system indoors in a laboratory that complies with the environmental conditions
recommended in the system Site Planning Guide. If the system is used in an environment or in a
manner not prescribed by AB SCIEX, the protection provided by the equipment can be impaired.
Unauthorized modification or operation of the system may cause personal injury and equipment
damage, and may void the warranty. Erroneous data may be generated if operating the
instrument while exceeding the recommended environmental conditions or operating with
unauthorized modifications. Contact an AB SCIEX representative for more information on
servicing the instrument.
WARNING! Biohazard: This symbol indicates a warning of biohazardous
materials. Read the warning and follow all precautions before performing any
operation described in the guide. Failure to do so can result in serious injury.
Tip! Provides useful information that helps apply the techniques and procedures in
the text for a specific need, and provides shortcuts, but is not essential to the completion
of a procedure.
i
Note: A note emphasizes significant information in a procedure or description.

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Shipping Labels
Regulatory Compliance
This system complies with the standards and regulations listed in this section. Applicable labels
have been affixed to the system.
Australia and New Zealand
•Electromagnetic Interference—AS/NZ CISPR 11 (Class A)
•Safety—AS/NZ 61010-1
Canada
•Electromagnetic Interference—CAN/CSA CISPR11. This ISM device complies
with Canadian ICES-001.
Table 1-1 Labels on the Crate
External Labels Definition Action
or
TIP N TELL
Blue beads in the arrow
indicate that the container was
tipped or mishandled.
Write on the Bill of Lading and
check for damage. Any claims
for tipping require a notation.

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•Safety—CAN/CSA C22.2 No. 61010-1, and CAN/CSA C22.2 No. 61010-2-061
Europe
•Electromagnetic Compatibility—EN 55011 (Class A), EN 61326-1
•Safety—EN 61010-1, EN 61010-2-061
•WEEE—2002/96/EEC
United States
•Electromagnetic Interference, FCC Part 15, Class A—This equipment has been
tested and found to comply with the limits for a Class A digital device, pursuant to
Part 15 of the FCC (Federal Communications Commission Compliance) Rules.
These limits are designed to provide reasonable protection against harmful
interference when the equipment is operated in a commercial environment. This
equipment generates, uses, and can radiate radio frequency energy and, if not
installed and used in accordance with the operator’s manual, can cause harmful
interference to radio communications. Operation of this equipment in a residential
area is likely to cause harmful interference in which case you will be required to
correct the interference, at your own expense. Changes or modifications not
expressly approved by the manufacturer could void your authority to operate the
equipment.
•Safety—UL 61010-1, IEC 61010-2-061
International
•Electromagnetic Compatibility—IEC 61326-1, IEC CISPR 11 Class A
•Safety—IEC 61010-1, IEC 61010-2-061
For more information, see the Declaration of Conformance included with the system.
Symbols and Labels on the Mass Spectrometer
Table 1-2 Labels on the Mass Spectrometer
External Labels Definition
WARNING: NO USER SERVICEABLE PARTS
INSIDE. REFER SERVICING TO QUALIFIED
PERSONNEL.
EN61326—1:2006 CLASS A, GROUP 1, ISM
EQUIPMENT