Beckman Coulter PA 800 plus User manual

A51977AC
February 2011
Pre-Installation Guide
PA 800 plus
Pharmaceutical Analysis
System
32 Karat™ Software Version 9.1 and
PA 800 plus Software Version 1.1
Beckman Coulter, Inc.
250 S. Kraemer Blvd.
Brea, CA 92821

Pre-Installation Guide
PA 800 plus Pharmaceutical Analysis System
32 Karat Software Version 9.1 and
PA 800 plus Software Version 1.1
PN A51977AC (February 2011)
Copyright © 2009-2011 Beckman Coulter, Inc.
Beckman Coulter, Inc. grants a limited non-exclusive
license to the owner or operator of a PA 800 plus
instrument to make a copy, solely for laboratory use,
of any portion or all of the online help and electronic
documents shipped with the PA 800 plus instrument.
Trademarks:
Following is a list of Beckman Coulter trademarks:
• Beckman Coulter®
• 32 Karat™
All other trademarks are the property of their respective
owners.
Find us on the World Wide Web at:
www.beckmancoulter.com and www.CELeader.com
Beckman Coulter Ireland, Inc.
Mervue Business Park, Mervue Galway, Ireland 353 91 774068
Beckman Coulter do Brasil Com e Imp de Prod de Lab Ltda
Estr dos Romeiros, 220 - Galpao G3 - Km 38.5
06501-001 - Sao Paulo - SP - Brasil
CNPJ: 42.160.812/0001-44
製造販売元 : ベ ッ ク マ ン･ コ ール タ ー株式会社
東京都江東区有明二丁目 5 番 7 号
贝克曼库尔特有限公司，
美国加利福尼亚州，Brea 市，S. Kraemer 大街 250 号，
邮编：92821 电话：[phone]

A51977AC iii
Revision History
Second Revision, A51977AC, February 2011
32 Karat Software version 9.1 patch
PA 800 plus Software version 1.1 patch
PA 800 plus Firmware version 9.2
Numerous syntax and grammatical edits
First Revision, A51977AB, December 2009
Revised corporate address.
Initial Issue, A51977AA, April 2009
32 Karat Software version 9.1
PA 800 plus Software version 1.1
PA 800 plus Firmware version 9.0

A51977AC
iv
Revision History

A51977AC v
Safety Notices
Symbols and Labels
Introduction
The following is a description of symbols and labels used on the Beckman Coulter PA 800 plus
Pharmaceutical Analysis System or shown in this manual.
WARNING
If the equipment is used in a manner not specified by Beckman Coulter, Inc., the
protection provided by the instrument may be impaired.
General Biohazard Symbol
This caution symbol indicates a possible biohazard risk from patient specimen contamination.
Caution, Biohazard Label
This caution symbol indicates a caution to operate only with all covers in position to decrease risk
of personal injury or biohazard.

A51977AC
vi
Safety Notices
Symbols and Labels
Caution, Moving Parts Label
This caution symbol warns the user of moving parts that can pinch or crush.
High Voltage Electric Shock Risk Symbol
This symbol indicates that there is high voltage and there is a risk of electric shock when the user
works in this area.
Class 1 Laser Caution Label
A label reading “THIS PRODUCT CONFORMS TO APPLICABLE REQUIREMENTS OF 21 CFR 1040 AT THE
DATE OF MANUFACTURE” is found near the Name Rating tag. The laser light beam is not visible.
Sharp Object Label
A label reading “CAUTION SHARP OBJECTS” is found on the PA 800 plus.
CAUTION
PARTS MOVE
AUTOMATICALLY
A015081L.EPS
144557-AB
A016352L.EPS
A016350L.EPS
CLASS 1 LASER PRODUCT
THIS PRODUCT CONFORMS TO
APPLICABLE REQUIREMENTS OF
21 CFR 1040 AT THE DATE OF
MANUFACTURE.
MANUFACTURED:
726024-C
CAUTION
SHARP OBJECTS
A16558-AA
A016351L.EPS

A51977AC vii
Safety Notices
Symbols and Labels
Recycling Label
This symbol is required in accordance with the Waste Electrical and Electronic Equipment (WEEE)
Directive of the European Union. The presence of this marking on the product indicates:
1. The device was put on the European Market after August 13, 2005.
2. The device is not to be disposed of via the municipal waste collection system of any member
state of the European Union.
It is very important that customers understand and follow all laws regarding the proper
decontamination and safe disposal of electrical equipment. For Beckman Coulter products bearing
this label, please contact your dealer or local Beckman Coulter office for details on the take back
program that facilitates the proper collection, treatment, recovery, recycling, and safe disposal of
this device.
Disposal of Devices Containing Mercury Components
This product contains a mercury-added part. Recycle or dispose of according to local, state, or
federal laws. It is very important that you understand and comply with the safe and proper disposal
of devices containing mercury components (switch, lamp, battery, relay, or electrode). The mercury
component indicator label can vary depending on the type of device.

A51977AC
viii
Safety Notices
Symbols and Labels
Restriction of Hazardous Substances (RoHS) Labels
These labels and materials declaration table (the Table of Hazardous Substance's Name and
Concentration) are to meet People's Republic of China Electronic Industry Standard SJ/T11364-2006
"Marking for Control of Pollution Caused by Electronic Information Products" requirements.
RoHS Caution Label
This logo indicates that this electronic information product contains certain toxic or hazardous
elements, and can be used safely during its environmental protection use period. The number in the
middle of the logo indicates the environmental protection use period for the product. The outer
circle indicates that the product can be recycled. The logo also signifies that the product should be
recycled immediately after its environmental protection use period has expired. The date on the
label indicates the date of manufacture.
RoHS Environmental Label
This logo indicates that the product does not contain any toxic or hazardous substances or
elements. The "e" stands for electrical, electronic, and environmental electronic information
products. This logo indicates that this electronic information product does not contain any toxic or
hazardous substances or elements, and is green and is environmental. The outer circle indicates
that the product can be recycled. The logo also signifies that the product can be recycled after being
discarded, and should not be casually discarded.

A51977AC ix
Safety Notices
Symbols and Labels
Alerts for Warning, Caution, Important, and Note
WARNING
WARNING indicates a potentially hazardous situation which, if not avoided, could
result in death or serious injury. The warning can be used to indicate the
possibility of erroneous data that could result in an incorrect diagnosis (does not
apply to all products).
CAUTION
CAUTION indicates a potentially hazardous situation, which, if not avoided, may
result in minor or moderate injury. It may also be used to alert against unsafe
practices. The caution can be used to indicate the possibility of erroneous data
that could result in an incorrect diagnosis (does not apply to all products).
IMPORTANT IMPORTANT is used for comments that add value to the step or procedure being performed.
Following the advice in the IMPORTANT notice adds benefit to the performance of a piece of equipment
or to a process.
NOTE NOTE is used to call attention to notable information that should be followed during installation, use,
or servicing of this equipment.

A51977AC
x
Safety Notices
Symbols and Labels

xi
Contents
Revision History, iii
Safety Notices,v
Symbols and Labels,v
Introduction,xiii
General Description, xiii
CHAPTER 1: Pre-Installation,1-1
Preparation Check List,1-1
Technical Support,1-1
Pre-Installation Check List,1-2
PA 800 plus ,1-2
Computer,1-2
Detectors,1-2
Options,1-2
CHAPTER 2: Site Requirements,2-1
Tabletop Space,2-1
Space Requirements,2-2
Ventilation Requirements,2-2
Electrical Requirements,2-3
CHAPTER 3: Specifications,3-1
PA 800 plus System,3-1
Computer Requirements,3-2
UV Detector,3-2
PDA Detector,3-3
LIF Detector,3-3
Sample Cooling,3-4

xii
Contents
CHAPTER 4: PA 800 plus System Training,4-1
Pre-Training Requirements,4-1
Additional Training,4-1

A51977AC xiii
Introduction
General Description
This Pre-Installation Guide assists designated operators in identifying the items required for
laboratory preparation so that installation can be completed efficiently and the system operated
successfully.
The supplies you must have on hand prior to the installation of the instrument are specified. Also
provided is a list of accessories available.
For your convenience, a pre-installation checklist is included to help you prepare for the
installation.
NOTE This manual applies to instruments running PA 800 plus software and also to instruments running field-
upgraded PA 800 Enhanced software.

A51977AC
xiv
Introduction
General Description

A51977AC 1-1
CHAPTER 1
Pre-Installation
Preparation Check List
The following is a summarized list of the items that must be addressed prior to installation. Mark
each item as it is completed. When these prerequisites have been met, contact your local Beckman
Coulter representative to schedule the installation.
• Appropriate table or bench (Tabletop Space in CHAPTER 2, Site Requirements)
• Suitable power source (Table 2.1 in CHAPTER 2, Site Requirements)
• Suitable laboratory environment (PA 800 plus System in CHAPTER 3, Specifications)
• Training prerequisites met (CHAPTER 4, PA 800 plus System Training)
Technical Support
If you encounter a problem that is not discussed in this guide, and you need technical support,
contact your local dealer, the provider of this product, or contact Beckman Coulter directly by using
the information below.
NOTE Whenever you call your local dealer or Beckman Coulter, be sure to have your registration material,
instrument serial number, and software version number available.
For future reference, record this information here.
Instrument Serial Number:
PA 800 plus Software Version:
32 Karat Software Version:
Firmware Version:
Dealer Name:
Dealer Phone Number:
Mail Beckman Coulter, Inc.
250 S. Kraemer Blvd.
Brea, CA 92821
Web address: www.beckmancoulter.com

A51977AC
1-2
Pre-Installation
Preparation Check List
Pre-Installation Check List
The following is a list of requirements and items necessary for installation of the PA 800 plus. Use
this list to check off the requirements and items you have and other items as you receive them. To
ensure a successful installation, please verify that you have these items prior to scheduling the
installation with your local office.
PA 800 plus
• Power Requirements
• Bench Space
• Installation Test Mix (shipped separately)
Computer
• Beckman Coulter Supplied
or
Equivalent Computer System
• Windows XP
• 32 Karat and PA 800 plus Software
• Printer (Optional)
• GPIB Communications Interface Board and Cable or USB-GPIB Cable
Detectors
• UV Detector (if ordered)
• PDA Detector
• LIF Detector (if ordered)
Options
• Filters (spare for each filter)
• Lasers
• External Detector Adapter

A51977AC 2-1
CHAPTER 2
Site Requirements
Tabletop Space
The PA 800 plus System is made up of the PA 800 plus unit and one each of the following:
• IBM PC Tower
• 22” Monitor
• Keyboard
• Mouse
Figure 2.1 PA 800 plus Dimensions

A51977AC
2-2
Site Requirements
Tabletop Space
Space Requirements
The instrument dimensions are shown in Figure 2.1. In addition to space for the instrument itself,
allow additional space for the computer and printer (if any). Figure 2.2 illustrates the recommended
system setup.
Ventilation Requirements
Adequate space must be provided around instrument for ventilation and access to the
communication’s connector. Allow at least 12 inches on the left side (facing instrument) and at least
4 inches on other sides Refer to Figure 2.2 for overall instrument dimensions.
Figure 2.2 Typical PA 800 plus System Setup
Table 2.1 Site Requirements
Item Requirement
Bench Dimensions
(Minimum Requirements)
Length: 6-8 feet (includes space for the PC Tower, monitor, and keyboard)
Width: 3 feet
Height: 3 1/2 feet
Supportable Weight: 500 - 600 lbs
Environment Indoor Use Only.
Ambient temperature range: 4°C (39°F) to 40° (104°F).
15°C (59°F) to 30°C (86°F) recommended without large temperature
fluctuations.
Power Requirements 100-120 or 200-240 VAC, 50-60 Hz, single phase,
130 W (nominal) for each module. Neutral to ground <0.5V

A51977AC 2-3
Site Requirements
Tabletop Space 2
Electrical Requirements
The PA 800 plus is shipped with a power cord suitable for North America (nominal 120 VAC, 60 Hz)
installations. A power cord suitable for non-North America installations will be provided by
Beckman Coulter. The instrument requires one grounded electrical outlet.
The power line to the laboratory should connect directly from a main power line transformer at a
power source known to be clear of erratic power loads, spikes, and electromagnetic interference.
Power lines reserved for the instrument must have adequate reserve capacity. Normal loading
should not exceed 50% of nominal capacity to allow for start-up loads and the addition of new
instruments.
Remember that the personal computer, printer, and accessories require additional AC outlets.

A51977AC
2-4
Site Requirements
Tabletop Space