CORNING Lambda EliteMax User manual

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Corning®Lambda™
EliteMax Semi-automated
Benchtop Pipettor
Service Manual
Catalog Number:
6070

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Table of Contents
1.0 Introduction........................................................................................................................................ 3
1.1 Overview........................................................................................................................................ 3
1.2 Symbols and Conventions............................................................................................................. 4
1.3 Safety Information ......................................................................................................................... 4
1.4 Instrument Identification ................................................................................................................ 6
1.5 Deck Positions and Orientation Convention.................................................................................. 7
1.6 Specifications ................................................................................................................................ 9
1.7 Initial Installation.......................................................................................................................... 10
1.8 Touch Screen User Interface ...................................................................................................... 10
2.0 Components Removal..................................................................................................................... 11
2.1 Liquid Head Removal.................................................................................................................. 11
2.2 Back Panel Removal................................................................................................................... 11
2.3 Front Panel Removal................................................................................................................... 13
2.4 Main Head Cover Removal ......................................................................................................... 14
2.5 Liquid Head Cover Removal ....................................................................................................... 15
2.6 Power Entry Cover Removal....................................................................................................... 16
3.0 Belts and Pulleys............................................................................................................................. 17
3.1 Up-Down Head Axis.................................................................................................................... 17
3.2 Main Axis..................................................................................................................................... 17
3.3 Single-head Axis.......................................................................................................................... 18
3.4 Liquid Head Pistons Axis............................................................................................................. 20
3.5 Linear Guideways Lubrication..................................................................................................... 20
4.0 Frame Alignment............................................................................................................................. 21
4.1 Tip Barrels Alignment.................................................................................................................. 21
4.2 Liquid Head Alignment ................................................................................................................ 21
4.3 Main Axis Alignment.................................................................................................................... 23
5.0 Electrical System............................................................................................................................. 24
5.1 Electrical Diagram ....................................................................................................................... 24
5.2 Motor Driver Board Pinout........................................................................................................... 25
5.3 Main Head Board Pinout ............................................................................................................. 26
5.4 Power Entry Module Pinout......................................................................................................... 26
5.5 AC External Power Supply.......................................................................................................... 27
5.6 Home Sensors............................................................................................................................. 27
5.7 Touch Screen Controller Pinout .................................................................................................. 28
5.8 Diagnostic and Error Codes ........................................................................................................ 29
6.0 Liquid Head Maintenance................................................................................................................ 32
6.1 Seals Replacement ..................................................................................................................... 32
6.2 Pistons Replacement................................................................................................................... 33

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1.0 Introduction
1.1 Overview
The Corning®Lambda™EliteMax Semi-automated Benchtop Pipettor can perform a variety
of liquid handling tasks including:
Plate fillings from reagents reservoirs
Serial dilutions, plate-to-plate transfers, and plate replication
Well-to-well transfers (cherry picking)
Accurately and precisely transferring liquids and volumes between microplates
Transferring by row or by column
More complex applications can be performed such as sample preparation, timed
reaction, PCR preparation, cell-based assays set up, tube-to-tube transfers, and more
About the Service Manual
This service manual provides valuable information to service and repair the instrument. It has
been written for the qualified engineers and technicians to service and perform basic repairs
and maintenance.
Please refer to the Corning Lambda EliteMax Semi-automated Benchtop
Pipettor Instruction Manual (CLS-AN-671DOC) for more information on how to
operate the instrument, perform calibrations, or change settings from the touch
screen controller.
Do not attempt to perform any procedure before carefully reading all instructions. Always
follow product labeling and manufacturer’s recommendations. Always use protective
eyewear, gloves, and suitable laboratory clothing when maintaining, servicing or operating
this or any other automated laboratory instrumentation. Always comply with all safety and
health standards.
Make sure the instrument is clean and decontaminated before performing any
service or repair.
No part of this publication may be transcribed, transmitted, reproduced, stored, or translated
into any language or computer language, in any form or by any means, without prior written
permission of Corning Incorporated.
Disclaimer
The information in this document is subject to change without notice. Corning Incorporated
reserves the right to revise this publication and to make changes from time to time in the
content hereof without obligation of Corning Incorporated to notify any person of such
revisions or changes.
Although this manual has been prepared with every precaution to ensure accuracy, Corning
Incorporated assumes no liability for any errors or omissions, nor for any damages resulting
from the application or use of this information.

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No liability for consequential damages
In no event shall Corning Incorporated be liable for any damages whatsoever arising from
the use or inability to use this product.
In no event shall Corning Incorporated be liable for any indirect or consequential damage for
the use of this product to produce other goods or materials.
In no event shall Corning Incorporated be liable or responsible for the use or integration of
this product with other systems by its user, its subsidiaries or any other party.
1.2 Symbols and Conventions
CAUTION: This symbol refers you to important operating and maintenance
(servicing) instructions within this product Service Manual. Failure to heed this
information may present a risk of damage or injury to persons or equipment.
1.3 Safety Information
During the operation, maintenance, or repair of the Corning®Lambda™EliteMax Semi-
automated Benchtop Pipettor, the following safety measures should be taken or, in
consequence, the safeguards provided by the Corning Lambda EliteMax Semi-automated
Benchtop Pipettor are likely to be damaged, the rated safety level to be reduced, and the
rated operation conditions to be affected. Corning shall not be in any way responsible for the
consequences resulting from the operator not observing the following requirements.
Grounding
AC power’s grounding should be reliable to safeguard against an electric
shock. The 3-pin plug supplied with the Corning Lambda EliteMax Semi-
automated Benchtop Pipettor power cable is a safety device that should be
matched with a suitable grounded socket. Never allow the third ground pin to
be floating. If the 3-pin plug cannot be inserted, it is recommended to ask an
electrician to install an appropriate power socket.
Keeping Away from Electric Circuits
The operator should not open the Corning Lambda EliteMax Semi-automated
Benchtop Pipettor without first consulting the Customer Service team.
Changing components or adjusting certain parameters inside the device must
be performed by certified professional maintenance personnel only. Do not
change any elements while the power is still on.
AC Power Considerations
Before turning on the power, always make sure that the main voltage is within
the range of required power supply and that the rating current of the power
socket meets the required specification.
AC External Power Supply Considerations
As an accessory of the Corning Lambda EliteMax Semi-automated Benchtop
Pipettor, the external AC power supply should be placed in a safe area. If it is
damaged, the AC power supply cannot be repaired, but instead must be
replaced by a new one. The external power supply should be free of any
objects and placed in a ventilated area during the Corning Lambda EliteMax
Semi-automated Benchtop Pipettor’s operation. Keep the power supply away
from high traffic areas.

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Connect the AC Power Line
While connecting the AC power line, the user should insert the plug firmly to
ensure good contact between the plug and socket. Pull the plug, but not the
cable, when the plug needs to be disconnected from the mains.
Design Environments
The Corning®Lambda™EliteMax Semi-automated Benchtop Pipettor should be placed in a
low-humidity, dust-free, well ventilated room without caustic gas, corrosive vapors, or
powerful magnetic interference. The Corning Lambda EliteMax Semi-automated Benchtop
Pipettor should never be operated near water sources such as pools and water pipes. Never
cover or obstruct the openings of the Corning Lambda EliteMax Semi-automated Benchtop
Pipettor as they are designed for ventilation and prevention of the device’s interior from
becoming too hot. When the instrument is running, the shortest distance between its
openings and the nearest object should be at least 20 inches (50 cm). Do not place the
device on a soft surface. Place the device on a stable, level bench or hood. Excessive jarring
or vibration during operation may affect the device’s performance. Operating conditions that
cause a high temperature environment will result in the degraded performance or failure of
the Corning Lambda EliteMax Semi-automated Benchtop Pipettor. Additionally, the device
should be protected against any kind of heat sources such as sunlight, ovens, or central
heating equipment. If the Corning Lambda EliteMax Semi-automated Benchtop Pipettor is to
sit idle for extended periods of time, it is recommended to disconnect the power line from the
mains and cover the device with a piece of soft cloth or plastic to prevent against dust.
CAUTION: If any of the following events occur, the operator is advised to
disconnect the power cable from the mains and contact your local Corning
representative or ask a certified maintenance engineer for assistance.
Liquid enters the device.
The device malfunctions, giving off an abnormal sound or odor.
The device falls onto the floor or the housing is damaged.
There are significant changes in the device’s performance.

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1.4 Instrument Identification

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1.5 Deck Positions and Orientation Convention

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Typical landscape layout orientation.
Typical portrait layout orientation.
NOTE: Portrait adapter between plates.
CAUTION: Before running any protocols, make sure ALL tip racks, plates,
reservoirs, and accessories share the same orientation to avoid possible
collision that can damage the instrument or the sample plate.

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1.6 Specifications
Performance Specifications
Pipetting Channels
12-channels for 96-well
format
Single-channel for 96-well
format
Volume Range
1 µL to 200 µL
1 µL to 200 µL
Plate Formats
96-well standard, shallow, deep well, microcentrifuge, V-,
U-, and flat-bottom
Functions and Protocols
Plate fillings, serial dilutions, plate-to-plate transfers, plate
replication, sample preparation, cherry picking protocol (for
single-channel head only), and other more complex
protocols can be implemented
Accuracy
20 µL
<±2.0%
<±2.0%
100 µL
<±1.5%
<±1.5%
200 µL
<±1.0%
<±1.0%
Precision
20 µL
<1.5% CV
<1.5% CV
100 µL
<1.0% CV
<1.0% CV
200 µL
<0.7% CV
<0.7% CV
NOTE: The instrument uses a programmable calibration algorithm, where aspiration,
dispense, and liquid speed can be adjusted for a particular reagent. Precision and
accuracy can be highly improved for a particular reagent and transfer volume.
Precision shown as percentage of coefficient of variation.
Multi-channel specifications represent the performance of all channels of a pipet.
All values shown as reference. Corning FX tips used. See NOTE above.
Technical Data
Dimensions (W x D x H)
Main Unit
Touch screen controller
External power supply
External power cord
Touch screen controller cable
20.5 x 11.3 x 14.2 in. (520 x 285 x 360 mm)
11.3 x 6.3 x 5.3 in. (284 x 160 x 135 mm)
55 in. (140 cm)
72 in. (183 cm)
60 in. (152.4 cm)
Weight
Main Unit
Touch screen controller
44 lbs. (20 kg)
3.3 lbs. (1.5 kg)
Power Requirements
Main power supply
Device input
100-240 VAC, 47-63 Hz
24 VDC, 120W (US, EU, UK, CH plug types included)
Operating Temperature
5°C to 40°C (relative humidity 80% up to 30°C or 45%
relative humidity at 40°C)
Storage Temperature
-10°C to +50°C

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1.7 Initial Installation
To install the unit:
1. Connect the Touch Screen Controller cable into the rear panel of the Corning®
Lambda™EliteMax Semi-automated Benchtop Pipettor.
2. Connect the round connector of the universal external power supply into the rear
panel of the instrument. Push in firmly until you feel it click into position.
3. Connect the AC power cord to the universal external power supply and then to the
AC wall power receptacle. The AC power receptacle should be able to supply approx.
300W and MUST be grounded to a true earth ground.
4. Power up the unit by rocking the Reset/Off switch located in the back of the Corning
Lambda EliteMax Semi-automated Benchtop Pipettor to the Reset position. The
instrument should boot up, and the home screen will appear in a few seconds.
Please refer to the Corning Lambda EliteMax Semi-automated Benchtop Pipettor Instruction
Manual (CLS-AN-671DOC) to operate the instrument.
1.8 Touch Screen User Interface

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2.0 Components Removal
2.1 Liquid Head Removal
1. Unplug the electric connector (C).
2. Remove the screws (1), and carefully remove the acrylic cover (A).
3. Remove the screws (2), and dismount the liquid head (B) from the instrument.
2.2 Back Panel Removal
1. Remove the indicated screws.
2. Carefully separate the back cover (A) from the instrument.

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2.3 Front Panel Removal
1. Remove the back panel.
2. Remove the indicated screws (1).
3. Carefully separate the pulley cover (A).
4. Remove the screws (2) and nuts (3).
5. Carefully slide out the front panel (B) to remove it from the instrument.

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2.4 Main Head Cover Removal
1. Gently and slowly move the main head down.
2. Remove the indicated screws.
3. Carefully remove the main head cover (A).

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2.5 Liquid Head Cover Removal
1. Remove the liquid head (refer to section 2.1).
2. Remove the indicated screws.
3. Carefully remove the liquid head cover (A).

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2.6 Power Entry Cover Removal
1. Remove the back and front panels.
2. Disconnect the associated wires and connectors from the main electronics board.
3. Remove the indicated screws.
4. Carefully remove the power entry cover (A).

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3.0 Belts and Pulleys
3.1 Up-Down Head Axis
1. Loosen the indicated screws, and move the stepper motor accordingly as shown.
2. If timing pulleys are replaced, remove the belt first.
3. After servicing the belt or the pulleys, adjust the belt tension and tighten the screws.
3.2 Main Axis
1. Loosen the indicated screws, and move the stepper motor accordingly as shown.
2. If the idler pulleys (1) are replaced, remove the belt first by loosening the pulley screw
nuts (2) and belt clamps screws (3).
3. After servicing the belt or the pulleys, adjust the belt tension and tighten the stepper
motor screws.

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3.3 Single-head Axis
1. Remove covers (A) and (B).
2. Loosen the screws (1) and then move stepper motor accordingly as shown.
3. If timing belt is replaced, remove the bracket (C) and single-head carriage (D).
4. After servicing the belt or the pulleys, adjust the belt tension and tighten the stepper
motor screws.
NOTE: If servicing or replacing the idler pulley (E), note the location and quantity of the
pulley’s shims. Use a small amount of lithium grease “Mobil Mobilux EP1” to lubricate the
components (Mobil Mobilux EP1 is recommended, but a similar low viscosity lithium grease
can be used as well). After assembly, make sure the idler pulley spins freely.

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3.4 Liquid Head Pistons Axis
1. Remove the liquid head and liquid head cover.
2. Loosen the idler pulley (A) and move it accordingly.
3. If the timing belt is replaced, remove the cover (B) (adhesive backed) and limit the
stroke screw (1), then drop down the complete main head and detach it from the
instrument.
4. To reassemble, follow the steps in reverse order.
5. After servicing the belt or pulleys, place a “1-2-3 block” as shown in the image and
check parallelism. At this point, factory timing marks should be aligned. If not, turn the
leadscrews individually as needed until the center bar is parallel to the 1-2-3 block
and timing marks are aligned. Adjust the belt tension and tighten the idler pulley (A).
NOTE: When detaching the main head from the instrument, be careful not to drop the ball
bearings when the carriage is separated from the guideway rail.
3.5 Linear Guideways Lubrication
Clean the rails and carriages before lubricating them. Use “Mobil Mobilux EP1” for
lubrication. Apply a small amount of lubricant and remove any excess grease that can collect
dust overtime.