GE IV-908 User manual

Valves IV-908, PV-908
Instructions
GE Healthcare

Important user information
All users must read this entire manual to fully
understand the safe use of Valves IV-908, PV-908.
WARNING!
The WARNING! sign highlights instructions
that must be followed to avoid personal injury.
It is important not to proceed until all stated
conditions are met and clearly understood.
CAUTION!
The Caution! sign highlights instructions that
must be followed to avoid damage to the
product or other equipment. It is important not
to proceed until all stated conditions are met
and clearly understood.
Note
The Note sign is used to indicate information
important for trouble-free and optimal use of
the product.
CE Certifying
This product meets the requirements of applicable CE-
directives. A copy of the corresponding Declaration of
Conformity is available on request.
The CE symbol and corresponding declaration of
conformity, is valid for the instrument when it is:
– used as a stand-alone unit, or
– connected to other CE-marked GE Healthcare
instruments, or
– connected to other products recommended or
described in this manual, and
– used in the same state as it was delivered from GE
Healthcare except for alterations described in this
manual.
Recycling
This symbol indicates that the waste of
electrical and electronic equipment must not
be disposed as unsorted municipal waste
and must be collected separately. Please
contact an authorized representative of the
manufacturer for information concerning the
decommissioning of equipment.
WARNING!
This is a Class A product. In a domestic environment
this product may cause radio interference in which
case the user may be required to make adequate
measures.

3
Instructions 56-8101-02 Edition AE
1 Introduction
Introduction 1
Valves IV-908 and PV-908 are motorised rotary 8-way valves. The valves are
used in ÄKTATMdesign chromatography systems. They are powered from the
ÄKTAdesignTM P-900 series system pump, and controlled from UNICORNTM
control system.
The valves have 8 positions and each position connects the central port with
one of the peripheral ports. The valve IV-908 is used on the low pressure side
(before the pump) and PV-908 on the high pressure side (after the pump).
The valve may be used to switch between sample and buffer solutions. Two
valves may be used to switch between columns.
Features:
• Completely swept flow path minimises
solvent or sample ”memory effect”.
• Flow rates up to 100 ml/min.
• All wetted parts are plastic PEEK.
Safety
WARNING! When using hazardous chemicals, take all suitable protective
measures, such as wearing protective glasses and gloves resistant to
the chemicals used. Follow local regulations and instructions for safe
operation and maintenance of the system.
IV-908 PV-908
PV-908
V-908

4Instructions 56-8101-02 Edition AE
1 Introduction

5
Instructions 56-8101-02 Edition AE
Installation 2
2 Installation
CAUTION! Before connecting Valves IV-908 or PV-908 ensure the power
is switched OFF at the system pump or for the complete system.
Unpacking
Unpack the instrument and check the items against the packing list.
Inspect the items for obvious damage which may have occured during
transportation.
1 Connect the valve with two UniNet cables
as a part of the UniNet 2 chain.
2 Set the ID-switch at the bottom to the
required valve number 0–9. The number
should correspond to that used in UNICORN.
Note: All valves must have different numbers.
3 Mount the valve vertically, in the way it
is shown in the user documentation of
your ÄKTAdesign chromatography system.
4 Apply an identification number from the
labels supplied. The number should be the same as the rotary switch at
the bottom of the valve. Place the number so that it is easily readable
from the front.
5 Connect the tubing. The valve has one main port marked i/o and
8 peripheral ports equally spaced marked 1–8.
The low pressure valve IV-908 has female
5/16”–24 UNF 2B connections.
The high-pressure valve PV-908 has female
UNF 10-32 2B connections.
7
8
6
3
2
1
i/o
7
8
6
3
2
1
i/o
5
454
Position 1 Position 2 etc.

6Instructions 56-8101-02 Edition AE
2 Installation

7
Instructions 56-8101-02 Edition AE
Operation 3
3 Operation
The valves are controlled from UNICORN.
Storage
Overnight: The valves can be left filled with a buffer.
Overnight and Long time storage: Flush the valves with water and then fill
with 20% ethanol.

3 Operation
8Instructions 56-8101-02 Edition AE

Maintenance 4
9
Instructions 56-8101-02 Edition AE
4 Maintenance
CAUTION! Only spare parts approved or supplied by GE Healthcare may
be used for maintaining and servicing the valves.
Period Action
Every 12 months Change channel plate and
or when required distribution plate
Cleaning-in-place
Pump a cleaning or sanitizing agent through the valve. The standard
recommendation is to pump 1 M NaOH for 30 minutes and wash out with
buffer.
WARNING! NaOH is injurious to health. Avoid spillage.
Changing channel plate and distribution plate
A valve kit is available, see ordering information in Reference Information.
1 Ensure that the valve is disconnected from the pump and the tubing are
disconnected.
2 Remove the 4 screws on the front using the supplied 3 mm Allen key.
Loosen each one equally in turn so the distribution plate comes off
parallel to the valve body.
3 Slide the screws out.
4 Remove the distribution plate containing the 8 peripheral ports.
5 Remove the old channel plate and insert a new one.
6 Remount a new distribution plate so that the text i/o is horizontal and
to the right of the central tubing connection. Using the Allen key, tighten
the 4 screws in turn, a little at a time, until the distribution plate is fixed
to the valve body.
PV-908
Channel plate
Distribution
plate

4 Maintenance
10 Instructions 56-8101-02 Edition AE
Recycling
This symbol indicates that the waste of electrical and electronic equipment
must not be disposed as unsorted municipal waste and must be collected
separately. Please contact an authorized representative of the manufacturer
for information concerning the decommissioning of equipment.