Miltenyi Biotec MultiMACS Cell24 Separator Plus User manual

MultiMACS™ Cell24 Separator Plus
User manual

Copyright © 2020 Miltenyi Biotec and/or its affiliates. All rights reserved.
No part of this user manual may be reproduced, stored in a retrieval system, transmitted, published, or distributed in any form or by any means,
electronically, mechanically, by photocopying, microfilming, recording, or otherwise, without the prior written consent of Miltenyi Biotec; however,
notwithstanding the foregoing, the owners of the MultiMACS™ Cell24 Separator Plus may make copies solely for purposes of training personnel in the
use and servicing of the unit within their business or organization. Maximal care has been taken by Miltenyi Biotec in the preparation of this user manual.
However, Miltenyi Biotec shall not be liable for any technical or editorial errors or omissions contained herein or for incidental or consequential damages in
connection with the furnishing, performance, or use of this document. The information in this document is provided “as is” without warranty of any kind,
and is subject to change without notice. MACS, the Miltenyi Biotec logo, MultiMACS, and StraightFrom are either registered trademarks or trademarks of
Miltenyi Biotec and/or its affiliates in various countries worldwide. All other trademarks mentioned in this document are the property of their respective
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only and not for therapeutic or diagnostic use.

MultiMACS™ Cell24 Separator Plus
User manual
Original instructions
Miltenyi Biotec B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach
Germany
Phone [phone]
Fax [phone]
[e-mail]
www.miltenyibiotec.com

Read the chapter Important safety information and all
other information in this user manual before using the
instrument
Before using the MultiMACS Cell24 Separator Plus, read the chapter Important safety information and all
other information contained in this user manual, including any safety and operating instructions. Pay special
attention to all warnings displayed on the instrument. Failure to read and follow these guidelines could lead to
improper or incorrect usage and result in damage to the instrument. Improper usage could also cause severe
personal injury, death, unpredictable results, instrument malfunction, and premature wear to components
shortening the lifetime of the instrument. Such actions may void your warranty. Keep the user manual and any
other safety and operating instructions provided with the instrument in a safe place accessible to all users for
future reference.
If you have a serious concern regarding the safe use of your instrument, contact your authorized Miltenyi Biotec
service provider or call Miltenyi Biotec Technical Support.
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Content
Important safety information 7
Wichtige Sicherheitsinformationen 15
Información importante de seguridad 23
Informations de sécurité importantes 31
1 Introduction 39
2 Installation 43
2.1 Components 43
2.1.1 Components included in the delivery 43
2.1.2 Accessories 44
2.1.3 Consumables 44
2.2 Assembly for benchtop use 44
3 Operating the instrument 47
3.1 Switching on and off 47
3.2 Stopping a moving magnet 47
3.3 Menu 48
3.3.1 Start menu 48
3.3.2 Process menu 49
3.3.3 Set up 49
3.3.4 New process 49
3.4 Buttons and symbols 49
3.5 Instructions for use 50
3.5.1 Placing columns into the MultiMACS Column Holder 50
3.5.2 Placing plates 51
3.5.3 Collecting the unlabeled fraction 52
3.5.4 Tip-Touch 52
3.5.5 Collecting the labeled fraction 53
3.6 Running a process 54
3.7 Viewing process parameters 54
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4 Setting up an experiment 55
4.1 Process selection 55
4.2 Columns 56
4.3 Target cell fraction and waste container 57
4.4 Buffer volumes 58
4.5 Large sample volumes 58
4.6 Magnetic labeling 58
5 Pre-defined processes 59
5.1 DEPLETE 59
5.2 POSSEL 60
5.3 POSSEL_2 60
5.4 POSSEL_SCA 61
5.5 POSSEL2_SCA 62
6 Custom processes 65
6.1 Creating a process 65
6.2 Replacing a process 67
6.3 Editing a process 67
6.3.1 Saving as new process 67
6.3.2 Changing parameters 68
6.4 Deleting a process 68
6.5 Testing plate height and distance for plate removal 68
7 Maintenance 71
7.1 Cleaning the instrument 71
7.2 Rotating the MultiMACS Cell24 Magnet and MultiMACS Column Holder 72
7.3 Exchanging fuses 74
7.4 Firmware version 74
7.5 Preparating for transport 74
8 Troubleshooting 77
8.1 Cross contamination by drops at the column tips 77
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8.2 Collision detection 77
8.3 Vacuum failure 77
8.4 Failed elution of labeled cells 78
8.5 Poor elution recovery 78
8.6 Error codes 78
9 Technical data and specifications 79
9.1 Technical data 80
9.2 EC/EU Declaration of Conformity 82
9.2.1 MultiMACS Cell24 Separator 82
9.2.2 MACS Elution Station 83
10 Technical support 85
11 Limited warranty 87
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EN
Important safety information
The MultiMACS Cell24 Separator Plus is designed for safe use when installed correctly, operated by professional
laboratory personnel, operated in accordance with general safety practices and the instructions in this user
manual.
Warnings and precautions
The guidelines in this section explain the potential risk associated with operating this instrument and provide
important supplemental safety information to minimize the risks. Follow the instructions carefully to protect
yourself, others, and the equipment from potential hazards and create a safe work environment. Use this
instrument only as specified by the manufacturer to avoid damage of equipment and injury to personnel.
Always follow local working area safety instructions and laboratory policies as well as standards for health,
safety, and prevention of accidents. Contact the local authorities governing electrical power supply, building
constructions, maintenance, or safety for more information about the safe installation and operation of the
instrument.
Hazard levels
Signal words are used to identify safety and property damage messages. The following signal words are used
throughout this user manual.
or WARNING! indicates a potentially hazardous situation, which, if not avoided, could result in death or serious
injury.
or CAUTION! indicates a potentially hazardous situation, which, if not avoided, may result in minor or
moderate injury. It may also be used to alert against unsafe practices.
Safety symbols
SAFETY ALERT. RISK OF DANGER. THE DOCUMENTATION NEEDS TO BE CONSULTED IN ALL CASES
WHERE THIS SAFETY SYMBOL IS USED, IN ORDER TO FIND OUT THE NATURE OF THE POTENTIAL
HAZARD AND ANY ACTIONS THAT HAVE TO BE TAKEN.
RISK OF ELECTRIC SHOCK.
STRONG MAGNETIC FIELD.
PERSONS CARRYING PACEMAKERS OR ELECTRONIC MEDICAL IMPLANTS MUST MAINTAIN DISTANCE.
RISK OF CRUSHING AND SHEARING OF BODILY PARTS.
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IMPORTANT SAFETY INFORMATION
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BIOHAZARD. RISK OF CONTAMINATION IF POTENTIALLY DANGEROUS BIOLOGICAL MATERIAL IS
USED.
ON (POWER SUPPLY).
OFF (POWER SUPPLY).
PROTECTIVE CONDUCTOR TERMINAL. SYMBOL IS ATTACHED ON THE INSIDE OF THE INSTRUMENT.
INFORMATION FOR SERVICE PERSONNEL.
FUSE.
WEEE (WASTE OF ELECTRICAL AND ELECTRONIC EQUIPMENT).
READ THE USER MANUAL BEFORE USING THE INSTRUMENT.
MANUFACTURER.
ORDER NUMBER.
TYPE NUMBER.
SERIAL NUMBER.
Safety labels
Notice the hazard points and safety symbols of the instrument.
• Keep safety labels and safety markings clean and legible.
• Inspect the safety labels and safety markings regularly and replace them if they are not legible or identifiable
from a safe viewing distance.
• Contact Miltenyi Biotec for replacement labels.
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Figure 1: The hazard points and the position of the safety symbols of the MultiMACS Cell24 Separator Plus.
Safety label 1 and 3
WARNING! Extremely strong magnetic field. Risk of severe personal injury to
persons carrying pacemakers or electronic medical implants – stay clear.
Keep all magnetically sensitive objects away from device.
Safety label 2 and 4
CAUTION! Tray in motion during operation. Hazard of crushing fingers.
Operate only with attached protection screen. Device must be able to be
tilted backwards.
Figure 2: Type labels of the MultiMACS Cell24 Separator Plus.
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IMPORTANT SAFETY INFORMATION
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The following safety label is attached to the type label of the MultiMACS Cell24 Separator.
WARNING! Avoid serious injury. Read and understand operating instructions
before installation or use. If manual is missing, obtain replacement from
Miltenyi Biotec.
General safety instructions
If the instrument is not working properly and/or the displayed instructions or messages advise you to contact
technical support, safe operation of the instrument is not longer possible. Immediately switch off and unplug
the instrument from the power outlet and contact an authorized Miltenyi Biotec service provider or Miltenyi
Biotec Technical Support.
Electricity and fire hazards
Potential risks arising from electrical devices include electric shock, short, and overheating.
Electric shock may lead to severe personal injury or death. An electric short and overheating
may lead to the spread of fire. Electronic equipment might emit sparks, which could ignite combustible
vapors or material resulting in explosion or fire. Do not use the instrument in areas classified as hazardous
locations; for example, in oxygen-laden environments.
The housing of the instrument is designed to reduce the risks of electric shock, electric short, and spread of fire.
Do not remove or penetrate any cover. Only authorized personnel must remove the other covers of the
instrument. Never push an foreign object through an opening into the instrument. Do not use the instrument if
lit has been opened or disassembled,
lit has been dropped or damaged,
lit has damaged or broken parts,
lit has a damaged power cable,
lan object has been entered through the ventilation slots,
lan object has been dropped into the instrument.
If flames or smoke appear, immediately switch off the power supply, unplug the instrument from the electrical
outlet, and contact an authorized Miltenyi Biotec service provider or Miltenyi Biotec Technical Support.
The instrument is intended for indoor use only. If fluids enter the instrument, it may lead to electric
shorts, electric shock, or fire. Take special care while handling liquids. Do not allow liquids to enter the
interior of the instrument. Protect the instrument against accidental spillages and splashes. Clean up spillages
immediately. Do not operate the instrument if liquids have spilled into the instrument. Do not use the
instrument in a wet and damp location. Avoid areas with high humidity or condensation. Moving the
instrument from a cold environment – such as a cold room at 5 °C – to room temperature may cause
condensation inside the instrument. In such cases, wait for the instrument to dehumidify before operating it.
Unplug the instrument from the electrical outlet before cleaning. Do not use liquid or aerosol cleaning agents;
always use a damp cloth.
Ensure adequate air circulation in the room when the instrument is operated. In the absence of adequate
circulation, ambient air may not cool the instrument to acceptable operating temperatures. Allow sufficient air
circulation around the instrument – at least 15 cm on all sides – during operation to ensure adequate cooling.
Do not place the instrument near radiators, heat registers, stoves, or other equipment (including amplifiers) that
generate heat. Protect the instrument from direct sunlight. Do not cover the slots and openings of the
IMPORTANT SAFETY INFORMATION
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instrument as these are provided for ventilation and protect the instrument from overheating. Do not place the
instrument in a built-in rack or similar confined spaces unless the space has been specifically designed to
provide proper ventilation. Follow the mounting instructions for the instrument.
Ensure that the main switch as well as the plug of the power cable are easily accessible and located as close to
the operator of the instrument as possible. If it is necessary to disconnect the power supply, unplug the cable
from the power outlet.
The instrument is equipped with a three-wire electrical grounding-type plug that has a third pin for grounding.
This plug fits into a grounded power outlet only. This is a safety feature. Do not try to insert the plug into a non-
grounded power outlet. If you cannot insert the plug into the outlet, contact your local electrician to replace the
outlet. The instrument should only be operated from a power source that meets the specifications mentioned
on the product´s electrical ratings label. If you have questions about the type of power source to use, contact
your authorized Miltenyi Biotec service provider or local power company. Do not use extension cords or power
strips. Do not overload an electrical outlet.
Only peripheral devices that comply to UL 60950 are allowed to be connected to the RS232 connector labeled
COM. In addition, only connect original MultiMACS Cell24 Separator Plus equipment to the connectors labeled
module 1 and module 2, and connect only the MultiMACS Cell24 Separator Plus display to the connector
labeled display. Only use connector cables less than 3 m in length.
Strong magnetic field
The MultiMACS Cell24 Separator Plus is equipped with an extremely powerful magnet, the MultiMACS Cell24
Magnet. Moreover, the MultiMACS Display also contains powerful magnets.
There is a risk of severe personal injury for persons carrying pacemakers, brain shunts, or
electronic medical implants.
Keep any magnetic information carriers (such as credit cards, magnetic tapes and floppy disks), any electronic
equipment (such as hearing aids, pacemakers, cerebral shunt, measuring and control instruments, computers,
and watches), and magnetizable tools and objects at a distance of at least 20 cm from the magnet cover and at
least 30 cm from the MultiMACS Display. These items may be affected or damaged by the magnetic field.
Mechanical hazards
Keep fingers etc. away from all moving parts of the MultiMACS Cell24 Separator Plus to avoid
crushing and shearing injuries or damage to the instrument.
If an object has been accidentally placed under the down-moving magnet, the physical resistance of the object
causes the instrument to tilt backwards, similar to a hydraulic jack. Do not place objects on the MultiMACS
Cell24 Separator Plus. Leave a space of at least 20 cm distance above and behind the MultiMACS Cell24
Separator Plus to ensure that the instrument is able to tilt backwards, thus avoiding potential crushing and
shearing injuries and minimizing instrument damage.
Do not circumvent any safety device or measurement. Keep the proper respective Protective Screen
attached to the MultiMACS Cell24 Separator Plus when operating it manually.
For usage in a liquid-handling robot, removal of the Protective Screen may be necessary. When using the
MultiMACS Cell24 Separator Plus integrated into a compatible automated liquid-handling system, assure that
the combined system, i.e., MultiMACS Cell24 Separator Plus, MultiMACS Cell24 Magnet, and liquid-handling
robot, meets all requirements of safety and function before starting automated processes. Thereby, particularly
take the protection of the operator into account.
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Chemical and biological hazards
Depending on the biological material used, contamination or infection may lead to severe personal injury or
death. All clinical samples must be considered potentially infectious. If biohazardous material is or has
been used, the operator must choose and wear personal safety equipment as indicated in the
warnings and precautions for the particular substance. The above safety precaution also accounts for any
hazardous chemical, including toxic or corrosive chemicals, acidic, or radioactive substances, that may be
present in the sample. Wear protective gloves and clothing, as well as safety glasses to prevent contact of the
substance with skin and eyes. Also protect mouth and nose as aerosols might leak from the system. Defective or
inadequate safety equipment is hazardous. The instrument must be operated in a safety hood if hazardous or
unknown materials are being processed. If hazardous material has been used or spilled, care must be taken to
thoroughly decontaminate the instrument. It is strictly prohibited to continue to handle contaminated
accessories or parts of the instrument.
Columns, plates, tubes and any other consumables that were in contact with biohazardous material must be
decontaminated before disposal. Liquid waste must be autoclaved or decontaminated using a disinfectant that
is appropriate for the specific pathogen, e.g., 10% bleach, isopropyl alcohol, or 70% ethanol. All liquid and solid
waste must be considered biohazardous and, therefore, must be handled taking universal laboratory
precautions. Waste disposal must be in accordance with any local regulations.
Servicing, transport and disposal
Unless otherwise specifically noted in this user manual or other Miltenyi Biotec documentation, do not
service the instrument yourself. Servicing and repair must be performed by qualified service personnel.
Improper or incorrect servicing or repair of the instrument can cause hazards to users, lead to unpredictable
results, cause instrument malfunctions or damage, as well as premature wear and tear and reduced life of the
instrument. It may also void your warranty.
When replacement or spare parts are required, ensure that the service provider uses only genuine Miltenyi
Biotec parts, or third-party parts specified and recommended by Miltenyi Biotec. Using unauthorized parts can
cause malfunctions of the instrument and impair results. Miltenyi Biotec does not honor any warranty or accept
any responsibility for instrument failure or damages resulting from the use of inappropriate parts. After
completing any service or repair work, ensure that your authorized Miltenyi Biotec service provider performs all
safety checks as required by the repair procedure to ensure that the instrument is operating correctly.
Only use options and upgrades recommended by Miltenyi Biotec. Inquire with your local Miltenyi
Biotec representative about Miltenyi Biotec's extensive instrument service and support arrangements, or refer to
www.miltenyibiotec.com/support.
The instrument should be transported with care in packaging specified by Miltenyi Biotec. Internal damage can
occur if the instrument is subjected to excessive vibration or is dropped. If the instrument needs to be shipped
back to the manufacturer for service, decontaminate the instrument to remove any hazardous material prior to
shipment. If you have questions regarding proper decontamination or shipment, contact Miltenyi Biotec
Technical Support for assistance.
IMPORTANT SAFETY INFORMATION
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Waste of Electrical and Electronic Equipment (WEEE) customer information
Please dispose of your end-of-life Miltenyi Biotec products in accordance with the applicable WEEE and
hazardous waste disposal legislation, which may differ by country or region.
Electrical and electronic equipment may contain hazardous substances which may have a serious detrimental
effect on the environment and/or human health. That is why all equipment must be specifically collected and
treated by designated waste facility centres and by qualified WEEE compliance schemes. By ensuring that you
dispose of your unwanted electrical and electronic equipment according to the applicable WEEE and hazardous
waste disposal legislation, you are helping to preserve our natural resources and protect human health.
Miltenyi Biotec is committed to protecting the environment. Miltenyi Biotec offers product end-of-life return
programs in many countries, and partners with licensed WEEE compliance schemes throughout the world.
Miltenyi Biotec lets you recycle your end-of-life Miltenyi Biotec equipment free of charge. The terms and
availability of this offer vary by geography because of differences in regulatory requirements. Please note that
depending on the type and use of your equipment, additional requirements may apply.
For more information, or if you wish to dispose of your end-of-life Miltenyi Biotec equipment, please contact
your local Miltenyi Biotec representative or Miltenyi Biotec Technical Support.
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IMPORTANT SAFETY INFORMATION
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DE
Wichtige Sicherheitsinformationen
Der MultiMACS Cell24 Separator Plus ist für einen sicheren Betrieb ausgelegt, wenn das Gerät richtig installiert,
von professionellem Laborpersonal bedient und entsprechend der Sicherheitsrichtlinien und Anweisungen in
diesem Benutzerhandbuch eingesetzt wird.
Warn- und Sicherheitshinweise
Die Sicherheitsrichtlinien in diesem Kapitel erläutern die Gefahren, die sich aus dem Betrieb dieses Gerätes
ergeben können und enthalten wichtige zusätzliche Informationen wie diese Risiken zu minimieren sind.
Befolgen Sie diese Sicherheitshinweise sorgfältig um sich, andere und das Gerät vor möglichen Gefahren zu
schützen und ein sicheres Arbeitsumfeld zu schaffen. Um Sach- und Personenschäden zu vermeiden, benutzen
Sie das Gerät ausschließlich nach Angaben des Herstellers.
Örtliche Arbeitsschutzbestimmungen, Laborrichtlinien, Sicherheitsnormen und Unfallverhütungsvorschriften
müssen jederzeit beachtet und eingehalten werden. Wenden Sie sich für weitere Informationen zur
Stromversorgung, Gebäudeinstallationen, Wartung und Sicherheit für die Installation dieses Gerätes an die
örtlichen Behörden und Ihren Stromversorger.
Gefahrenstufen
Gefahrensymbole werden verwendet, um auf Sicherheits- und Sachschadenhinweise aufmerksam zu machen.
Folgende Gefahrensymbole werden in diesem Benutzerhandbuch benutzt.
oder WARNING! bezeichnet eine Gefahrensituation, die, falls sie nicht vermieden wird, zum Tode oder
schwerwiegenden Verletzungen führen kann.
oder CAUTION! bezeichnet eine Gefahrensituation, die, falls sie nicht vermieden wird, zu leichteren oder
mittelschweren Verletzungen führen kann. Es kann auch verwendet werden, um vor unsicherem Gebrauch zu
warnen.
Gefahrensymbole
WARNZEICHEN. GEFAHRENRISIKO. DIESES BENUTZERHANDBUCH MUSS IMMER KONSULTIERT
WERDEN, WENN DIESES WARNZEICHEN BENUTZT WIRD, UM MEHR ÜBER DIE MÖGLICHEN GEFAHREN
UND ENTSPRECHENDE HANDLUNGSANWEISUNGEN ZU ERFAHREN.
GEFAHR EINES STROMSCHLAGS.
STARKES MAGNETFELD.
PERSONEN MIT HERZSCHRITTMACHER ODER ELEKTRONISCHEN MEDIZINISCHEN IMPLANTATEN
MÜSSEN ABSTAND HALTEN.
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QUETSCH- UND SCHERGEFAHR.
BIOLOGISCHE GEFÄHRDUNG. RISIKO DER KONTAMINATION, WENN MIT MÖGLICHERWEISE
GEFÄHRLICHEN BIOLOGISCHEN SUBSTANZEN GEARBEITET WIRD.
AN (STROMVERSORGUNG).
AUS (STROMVERSORGUNG).
SCHUTZLEITERANSCHLUSS. DIESES SYMBOL IST INNERHALB DES GERÄTS ANGEBRACHT UND STELLT
EINEN HINWEIS FÜR DAS SERVICEPERSONAL DAR.
SICHERUNG.
ENTSORGUNG VON ELEKTRO- UND ELEKTRONIK-ALTGERÄTEN.
LESEN SIE DAS BENUTZERHANDBUCH VOR VERWENDUNG DES GERÄTES.
HERSTELLER.
BESTELLNUMMER.
MODELLNUMMER.
SERIENNUMMER.
Sicherheitskennzeichnungen
Beachten Sie die Gefahrenhinweise und Sicherheitssymbole des Gerätes.
• Halten Sie die Warnaufkleber und Sicherheitskennzeichnungen sauber und lesbar.
• Überprüfen Sie die Warnaufkleber und Sicherheitskennzeichnungen regelmäßig und ersetzen Sie diese, wenn
sie nicht mehr lesbar oder aus sicherer Entfernung nicht zu erkennen sind.
• Kontaktiern Sie Miltenyi Biotec, um Ersatzaufkleber zu erhalten.
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Figure 1: Warnhinweise und Position der Sicherheitssymbole auf dem MultiMACS Cell24 Separator Plus.
Sicherheitsaufkleber 1 und 3
WARNUNG! Extrem starkes Magnetfeld. Gefahr schwerer Verletzungen für
Personen mit Herzschrittmacher oder elektronischen medizinischen
Implantaten. Abstand halten. Alle magnetisch empfindlichen Gegenstände
vom Gerät fernhalten.
Sicherheitsaufkleber 2 und 4
Vorsicht! Halter bewegt sich während des Betriebs. Quetschgefahr für die
Finger. Nur mit angebrachter Schutzblende betreiben. Gerät muss nach
hinten gekippt werden können.
Figure 2: Typenschilder des MultiMACS Cell24 Separator Plus.
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Der nachfolgende Sicherheitsaufkleber ist auf dem Typenschild des MultiMACS Cell24 Separators befestigt.
WARNUNG! Vermeiden Sie schwere Verletzungen. Vor der Installation oder
Inbetriebnahme ist die Bedienungsanleitung zu lesen. Wenn die Anleitung
fehlt, fordern Sie Ersatz bei Miltenyi Biotec an.
Allgemeine Sicherheitshinweise
Falls Ihr Gerät nicht einwandfrei funktioniert und/oder Anzeigen auf dem Display Sie dazu auffordern den
technischen Kundendienst zu kontaktieren, ist die Betriebssicherheit des Gerätes nicht länger gewährleistet.
Schalten Sie das Gerät sofort aus, ziehen Sie den Netzstecker und kontaktieren Sie einen autorisierten Miltenyi
Biotec Servicedienstleister oder den Miltenyi Biotec Technical Support.
Elektrische Gefährdung und Brandgefahr
Elektrische Geräte bergen das Risiko eines Stromschlags, Kurzschlusses und der Überhitzung.
Ein Stromschlag kann zu schweren Verletzungen und bis zum Tod führen. Ein elektrischer
Kurzschluss sowie Überhitzung kann eine Brandursache darstellen. Elektrische Geräte können
Funken schlagen, welche leichtentflammbare Dämpfe oder Materialien entzünden und somit zu Feuer und
Explosionen führen können. Benutzen Sie das Gerät nicht in ausgewiesenen Gefahrenzonen, z.B. in
sauerstoffangereicherten Umgebungen.
Das Gehäuse des Gerätes dient dazu das Risiko eines elektrischen Stromschlags, Kurzschlusses und Feuers zu
reduzieren. Mit Ausnahme der vorderen Abdeckungen, entfernen oder durchdringen Sie keine
Abdeckungen. Jegliche andere Abdeckung darf nur von autorisiertem Personal entfernt werden. Führen Sie
nie einen Fremdkörper durch eine Öffnung in das Gerät ein. Benutzen Sie das Gerät nicht, wenn:
les offen oder zerlegt ist,
les fallengelassen wurde oder beschädigt ist,
lTeile beschädigt oder defekt sind,
ldie Netzanschlussleitung beschädigt ist,
lein Gegenstand in die Belüftungsschlitze eingedrungen ist,
lein Fremdkörper in das Gerät gefallen ist.
Wenn Flammen oder Rauch auftreten, schalten Sie das Gerät unverzüglich aus, ziehen Sie den Netzstecker und
kontaktieren Sie einen autorisierten Miltenyi Biotec Servicedienstleister oder den Miltenyi Biotec Technical
Support.
Das Gerät ist ausschließlich für den Betrieb in Innenräumen ausgelegt. Sollten Flüssigkeiten in das Gerät
gelangen, kann es zu Kurzschluss, Stromschlag oder Feuer kommen. Seien Sie vorsichtig im Umgang
mit Flüssigkeiten. Verhindern Sie, dass Flüssigkeit in das Innere des Gerätes gelangt. Schützen Sie das Gerät vor
verschütteten oder verspritzten Flüssigkeiten.
Beseitigen Sie ausgetretene oder verschüttete Flüssigkeit sofort. Benutzen Sie das Gerät nicht, sollte Flüssigkeit
in das Innere des Gerätes gelangt sein. Setzen Sie das Gerät nicht in einer nassen oder feuchten Umgebung ein.
Vermeiden Sie Arbeitsbereiche mit hoher Luftfeuchtigkeit oder Kondensation. Das Überführen des Gerätes von
einer kalten Umgebung, z.B. aus einem Kühlraum bei 5 °C, in einen Raum mit Raumtemperatur, kann zu
Kondensation im Inneren des Gerätes führen. Warten Sie in solchen Fällen mit der Benutzung des Gerätes, bis
dieses getrocknet ist. Ziehen Sie den Netzstecker vor der Reinigung des Gerätes. Verwenden Sie keine Flüssig-
oder Sprühreinigungsmittel, sondern nur ein feuchtes Tuch.
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