Pall PadMixer 1000 Premium User manual

020-17467-00 Instructions For Use PadMixer 1000 Premium RevD
Filtration. Separation. Solution.SM
Instructions For Use
PadMixerTM 1000 Premium Mixer
USD 3188

020-17467-00 Instructions For Use PadMixer 1000 Premium RevD
www.pall.com/biopharm 2
Contents
1. Introduction.................................................................................................................. 4
2. Safety warnings ........................................................................................................... 4
3. Assembly and commissioning.................................................................................... 4
4. Touch screen operation .............................................................................................. 5
General................................................................................................................... 5
Start-up screen....................................................................................................... 5
Main screen –main menu....................................................................................... 5
4.3.1. Select recipe.................................................................................................... 7
4.3.2. Test Mode........................................................................................................ 7
4.3.3. Settings............................................................................................................ 9
4.3.4. Inflate............................................................................................................. 17
4.3.5. Print............................................................................................................... 17
4.3.6. Reset............................................................................................................. 17
4.4 Troubleshooting.................................................................................................... 18
4.5 Error Messages .................................................................................................... 19
4.6 Information............................................................................................................ 19
5Installation and use of mixing biocontainer............................................................. 21
5.1 Installing the mixing biocontainer.......................................................................... 21
5.2 Filling the mixing biocontainer............................................................................... 23
5.3 Setting the mixing angle on the drive unit.............................................................. 26
5.4 Connecting the mixing biocontainer to the drive unit............................................. 27
5.5 Adding powders.................................................................................................... 31
5.6 Creating a recipe .................................................................................................. 32
5.6.1 Guidelines to define the correct connection height......................................... 32
5.6.2 Mixing speed and mixing angle limitations..................................................... 32
5.6.3 Acceleration and deceleration limitations....................................................... 33
5.7 Height adjustment................................................................................................. 33
5.8 Inflating the mixing biocontainer............................................................................ 34
5.9 Starting the mixing cycle....................................................................................... 35
5.10 Emptying the mixing biocontainer ......................................................................... 35
5.11 Emergency stops.................................................................................................. 37
6Cleaning, maintenance and inspection activities.................................................... 38
6.1 Cleaning ............................................................................................................... 38
6.2 Maintenance and inspection ................................................................................. 38
6.3 Retrieving a lost password.................................................................................... 38

020-17467-00 Instructions For Use PadMixer 1000 Premium RevD
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6.4 Replacing the printer roll....................................................................................... 38
6.5 Adjusting the inflation pressure............................................................................. 39
6.6 Replacing the motor.............................................................................................. 40
6.7 Uploading a new PLC code................................................................................... 41
7General machine specifications ............................................................................... 47
7.1 Materials............................................................................................................... 47
7.2 Capacity................................................................................................................ 47
7.3 Noise level............................................................................................................ 47
7.4 Operating temperature.......................................................................................... 47
8Service........................................................................................................................ 47
9Warranty..................................................................................................................... 48

020-17467-00 Instructions For Use PadMixer 1000 Premium RevD
www.pall.com/biopharm 4
1. Introduction
The purpose of this manual is to inform the users about the safe and correct use of the
PadMixer 1000 Premium. This includes all persons who have the task of installing,
commissioning, adjusting, maintaining, cleaning, repairing, transporting or scrapping the
machine. Before using this machine all persons involved should thoroughly read and
understand the user manual. All safety precautions and safety provisions in use in the
company must be known and respected.
This user manual must always be available near the machine. It is very important that all
instructions are carefully followed and, where appropriate, they should be incorporated into
the user’s standard operating procedures. If some of the procedures do not suit your needs,
please consult your Pall distributor before finalizing your system. Use of this product in a
manner other than in accordance with Pall’s current recommendations may lead to injury or
product loss. Pall cannot accept liability for such injury or loss.
2. Safety warnings
Operation outside the specifications defined in this manual may cause personal injury
and result in damage to the equipment.
No operations (cleaning, maintenance, ...) may be performed on the machine if the
machine is not switched off. Protections around moving parts may not be removed.
3. Assembly and commissioning
It is not permitted to move the machine when a tank and/or mixing biocontainer is connected
to it. To move the machine push it from the backside.
Do not attempt to move the machine by pushing/pulling the mixing head.
Requiredfacilities:
Electricity:
The system 701024 can be used on a single phase net of 220V.
The system 701039 can be used on a single phase net of 110V.
The fuse present in the local power supply cabinet has to be minimum
16Ampère, with a curve C or curve D.
In case a differential switch is present in the local power supply
cabinet, it has to be type A or type B.
Compressed air:
Min. 3 bar, max. 8 bar.
Use of nitrogen is permitted.
The connection of the system to the compressed air system is effected
by connecting a 6 mm ID compressed air hose to the compressed air
coupling closest to the rear of the machine.
A compressed air cable is provided on the coupling closest to the front
of the machine with a fast coupling to be connected to the mixing
biocontainer.
The outgoing pressure (to the mixing biocontainer) can be adjusted by
means of the manometer underneath the mixing head cover plate. This
pressure is preset to a maximum of 500 mbar.

020-17467-00 Instructions For Use PadMixer 1000 Premium RevD
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The machine is ready for use as soon as the electricity is connected. Connection of the air
supply is not necessary for the functioning of the machine, only for the inflation.
Voltage is applied to the machine by means of the main switch fitted on the door of the
electrical cabinet. All other controls are effected using the Touch Screen.
4. Touch screen operation
General
All items (text & symbols) with a light blue background fulfil a certain function and can
be touched to perform the underlying function or to change the underlying adjustment.
Also the start, pause and stop symbols can be touched to perform their function.
The following symbol appears in the top left corner on different screens and can be used to
return to the previous screen and finally to the main menu:
Start-up screen
A screen saver appears when the main power switch is switched on. The main screen is
shown when the screen is touched.
Main screen –main menu
Figure 1: Main Menu
The main screen consists of the following fields:
Control buttons: Start - Pause - Stop
Table with Set and Actual process parameters
oRPM: Mixing speed expressed in revolutions per minute
oMixing time: expressed in hours : minutes : seconds
oAlternation time: expressed in hours : minutes : seconds