PerkinElmer OPERA PHENIX PLUS User manual

OPERA PHENIX®PLUS
Site Readiness

Release History
Revision Publication Date
B 2020-10-20
Service Contact
Information: http://www.cellularimaging.com
Portal: https://evoportal.perkinelmer.com
Notices
The information contained in this document is subject to change without notice.
Except as specifically set forth in its terms and conditions of sale, PerkinElmer makes no
warranty of any kind with regard to this document, including, but not limited to, the
implied warranties of merchantability and fitness for a particular purpose.
PerkinElmer shall not be liable for errors contained herein for incidental consequential damages in
connection with furnishing, performance or use of this material.
Copyright Information
This document contains proprietary information that is protected by copyright. All rights are
reserved. No part of this publication may be reproduced in any form whatsoever or translated into
any language without the prior, written permission of PerkinElmer, Inc.
Copyright © 2020 PerkinElmer, Inc.
Trademarks
Registered names, trademarks, etc. used in this document, even when not specifically marked as
such, are protected by law.
PerkinElmer is a registered trademark of PerkinElmer, Inc.
Opera Phenix is a registered trademark of PerkinElmer, Inc.
Harmony is a registered trademark of PerkinElmer, Inc.
plate::handler is a trademark of PerkinElmer, Inc.
plate::works is a trademark of PerkinElmer, Inc.
Intel is a registered trademark of Intel Corporation
Xeon is a registered trademark of Intel Corporation
Microsoft is a registered trademark of Microsoft Corporation
Internet Explorer is a registered trademark of Microsoft Corporation
Windows and Windows Vista are registered trademarks of Microsoft Corporation
JavaScript is a registered trademark of Sun Microsystems

Contents
1 Introduction 6
2 Requirements 9
2.1 Instrument Overview 10
2.2 Computer (Harmony PC) 11
2.3 Dimensions 12
2.3.1 Installation on PerkinElmer Opera Phenix Heavy Duty Lab Cart 14
2.3.2 Installation on Table (free-standing) 16
2.3.3 Installation with Automation Upgrade 17
2.4 Electrical Requirements 19
2.4.1 Cable Lengths 19
2.4.2 Country Kits 20
2.5 Environmental Requirements 21
2.6 Biosafety 21
2.7 Gas Requirements (optional) 23
2.8 Delivery Requirements 24
2.8.1 General 24
2.8.2 Opera Phenix Plus 24
2.8.3 Automation Upgrade (optional) 25
2.8.4 Automated Incubator (plate::handler system) 26
3 IT Policy 27
3.1 Network Integration 28
3.1.1 Overview 28
3.1.2 Simple Integration 29
3.1.3 Alternative Solutions 30
3.1.4 Automation Upgrade (plate::handler) 32
3.1.5 Columbus 32
3.2 Security Updates / Servicing Channel 35
3.2.1 Microsoft Windows 35
3.2.2 Microsoft Windows 10 IoT Enterprise 2016/2019 LTSC 35
3.2.3 Microsoft SQL Server 36
3.3 Requirements for Harmony Installation on an Office PC 37
3.4 Computer Systems 38
3.4.1 Network 38
3.4.2 Hardware 38
3.4.3 Operating System, Software & Software Applications 39
3.4.4 Data 40
3.4.5 Back Up 40
3.4.6 Security Settings & Anti-Virus Protection 41
3.5 Computer Users 41
3.6 Remote Support 42
4 Confirmation Fax/Email 43

Opera Phenix Plus – Site Readiness 5

1 Introduction
1 Introduction
6 Opera Phenix Plus – Site Readiness

This document describes the dimensions, installation and IT requirements of the
Opera Phenix Plus®Plus High Content Screening System.
Order Review
Please review this order. Record any discrepancies between the PerkinElmer order
and your purchase order, along with any agreements or commitments made by your
PerkinElmer sales representative that are NOT listed on the order. Let your sales
representative know about these discrepancies and/or commitments with your Site
Readiness confirmation.
Notice
The last page of this document needs to be filled and sent back to
your PerkinElmer Sales Representative via fax/email. The Opera
Phenix Plus will not be shipped until confirmation fax/email has been
received by PerkinElmer.
The Way of Your Opera Phenix Plus
1. Manufacturing of main unit: To achieve maximum robustness, the basic unit of
your Opera Phenix Plus is manufactured within a small series.
2. You receive the Site Readiness document.
3. Customization: Your Opera Phenix Plus is equipped with the features you
ordered.
4. Internal Acceptance Test (IAT)
To assure that all components of your Opera Phenix Plus work within the
specifications, the performance of the whole system is checked thoroughly.
5. Packaging: All devices and accessories are packed in specially designed
transport boxes.
6. You send the Site Readiness confirmation form to PerkinElmer.
7. Pick up: The packed Opera Phenix Plus is picked up by our co-operating shipper.
8. Delivery to you: Direct transport by truck or transport by air cargo.
9. Setting up by Service: Your system is unpacked, installed and set up by
PerkinElmer Service.
10. Site Acceptance Test (SAT)
Our Field Service engineer will test the instrument in order to ensure that its
performance meets manufacturing specifications.
Note: The SAT procedure is not intended as a substitute for an IQ/OQ
qualification process.We will not provide an IQ/OQ qualification document for the
Opera Phenix Plus instrument.We recommend a PerkinElmer service contract
for keeping up and confirming of proper functionality of the instrument during its
life time.
11. Familarization: After an introduction and device familarization by our Field
Service engineer you can start working with your new Opera Phenix Plus.
12. On-site user training: We offer an additional advanced user training upon request.
1 Introduction
Opera Phenix Plus – Site Readiness 7

2 Requirements
2 Requirements
Opera Phenix Plus – Site Readiness 9

2.1 Instrument Overview
Base Instrument
1. Controls and connections (left)
Network connection, power switch
2. Status display
3. Lid
Access to objectives and sample
chamber
4. Transfer position
Load/eject sample plate
5. Front door
Access to bottles of water immersion
system / humidity control
6. Controls and connections (right)
Manual release for lid, CO2connection,
mains connection, fuses
Optional Pipettor
1. Pipettor housing front door
Access to pipettor, instrument deck
and instrument lid
2. Pipettor housing side door
Access to transfer positions and tip
boxes (also by robot in case of
automated env.)
3. Pipettor head
4. Status display
5. Reagent reservoirs
6. Tip disposal
7. Transfer positions and tip boxes
8. Instrument deck and instrument lid
2 Requirements
10 Opera Phenix Plus – Site Readiness

2.2 Computer (Harmony PC)
Computer specifications are subject to change without notice.
Component Configuration
Processor Dual Intel®Xeon®≥ 8Cores
Operating system Microsoft®Windows®10, 64bit
RAM ≥64GB
Graphic card NVIDIA ≥4GB video memory
Network interface Gigabit + 10Gigabit Ethernet
Hard drive ~8TB usable storage (RAID5), expandable up to
36TB
Monitor ≥30" LCD
2 Requirements
Opera Phenix Plus – Site Readiness 11

2.3 Dimensions
The Opera Phenix Plus system consists of Opera Phenix Plus device, Harmony PC
and monitor/keyboard cart. The setup and installation options are described in the
following chapters.
Notice
The Opera Phenix Plus is sensitive to vibrations. Blurred images can
be the consequence.
lPut the Opera Phenix Plus on a very stable bench or table.
lDo not put other devices on the same table which cause
vibrations (e.g. a centrifuge).
lAvoid any shocks or vibrations during measurements.
Component Size [cm]
(W×D×H)
Size [in] Weight [kg] Weight [lb]
Opera Phenix Plus
Plus
Instrument height
(sample lid opened)
138 × 66
85
55 × 26
34
270-300 595-662
Opera Phenix Plus
Plus with optional
pipettor
Instrument height
(housing
closed/opened)
138 × 66
95/138
55 × 26
38/55
320-350 705-772
Harmony PC 22 × 53 × 44 9 × 21 × 18 17 38
Monitor/Keyboard Cart
(keyboard tray in/out)
67 × 58/74 26 × 23/29 41 91
Opera Phenix Heavy
Duty Lab Cart
(optional)
140 × 95* × 79 56 × 38* × 31 170 375
The table will come on 4 feet, 50cm² per single foot.
plate::handlerFLEX
(optional)
214 × 95 × 181
(overall)
84 × 38 × 71 135 298
plate::handler FLEX
and incubator
(optional)
274 × 95 × 181
(overall)
108 × 38 × 71 225 496
* Rear shelf can be removed for transport, thereby depth is reduced to 80 cm (32 in).
2 Requirements
12 Opera Phenix Plus – Site Readiness

Instrument Height
Please note that you will need some space above the instrument for opening the
sample lid.
With Optional Pipettor
Please note that you will also need some additional space for opening the front door
and side door of the pipettor housing.
Monitor/Keyboard Cart
2 Requirements
Opera Phenix Plus – Site Readiness 13

2.3.1 Installation on PerkinElmer Opera Phenix Heavy Duty
Lab Cart
We recommend to install the Opera Phenix on the optionally available Heavy Duty Lab
Cart. It is a stable basis for the instrument and especially designed to carry the Opera
Phenix. Since the table is rollable you can easily move the whole system, if
necessary. Optimal ventilation is ensured by perforated metal plates in the back and a
perforated rear shelf which ensures sufficient wall stand-off. Behind the table doors
there is plenty of space for the Harmony PC and other accessories. Positioning
brackets allow secure and accurate connection to PerkinElmer automation upgrades.
2 Requirements
14 Opera Phenix Plus – Site Readiness

* If the space required during delivery is not available in the lab, installation can also
take place in a different room, as long as the table can be rolled to the destination lab.
** Rear shelf of the Opera Phenix Heavy Duty Lab Cart can be removed for transport,
in this case depth is reduced to 80 cm (32 in).
2 Requirements
Opera Phenix Plus – Site Readiness 15

2.3.2 Installation on Table (free-standing)
The table should be rollable, if possible. If it is not rollable, “Working area I” will be
required during service visits.
* If the space required during delivery is not available in the lab, installation can also
take place in a different room, as long as the table can be rolled to the destination lab.
2 Requirements
16 Opera Phenix Plus – Site Readiness

2.3.3 Installation with Automation Upgrade
2.3.3.1 plate::handler FLEX
With the optional automation upgrade, the Opera Phenix Plus and the plate::handler
FLEX robot are installed on the provided workstation. An installation on tables provided
by the customer is not possible.
* "Working area I" is required during service visits. The depth of this area can be
reduced from 80 to 15 cm if the automation system consists only of the plate:handler
robot (no incubator) and if the entire system is rollable.
** If the space required during delivery is not available in the lab, installation can also
take place in a different room, as long as the table can be rolled to the destination lab.
2 Requirements
Opera Phenix Plus – Site Readiness 17

2.3.3.2 plate::handler FLEX + Incubator
For requirements of the optional incubator see also chapter2.8.4 .
* "Working area I" is required during service visits. The depth of this area can be
reduced from 80 to 15 cm if the automation system consists only of the plate:handler
robot (no incubator) and if the entire system is rollable.
** If the space required during delivery is not available in the lab, installation can also
take place in a different room, as long as the table can be rolled to the destination lab.
2 Requirements
18 Opera Phenix Plus – Site Readiness

2.4 Electrical Requirements
One individual power socket (separate circuit) is required for each system component
(see below).
Device Power Specification Power Consumption
(Max.)
Opera Phenix Plus 100 - 240 V, 50 - 60 Hz 1500 VA
Harmony PC 100 - 240 V, 50 - 60 Hz 1300 W
Monitor 100 - 240 V, 50 - 60 Hz 120W
plate::handler FLEX
(only with automation
upgrade)
100-120 V, 50 or 60Hz
or
220-240 V, 50 or 60Hz
200VA (10A fuse)
The table indicates the max. power consumption of the devices. During normal
operation the Opera Phenix Plus system (consisting of instrument, PC and monitor)
has a typical power consumption of 800 W (2730 BTU/hr).
Further requirements for plate::handler FLEX:
lMaximum rated short-circuit current: 1.5kA
lMaximum mains impedance: 2.7Ω
lEarthing system: TN-C-S
2.4.1 Cable Lengths
The power cords for instrument and PC as well as all monitor cables (Display Port,
USB and power cord) are always delivered with a length of ≥5m (197in).
2 Requirements
Opera Phenix Plus – Site Readiness 19

2.4.2 Country Kits
The instrument will be delivered with the corresponding Country Kit for your location. It
includes power cords suitable for your country and a keyboard with a corresponding
layout.
Notice
Use only the power cords provided by PerkinElmer. The images and
descriptions of the power plugs only illustrate the plug form which will
be delivered. They are not intended as full specification of the power
cord.
Country Kit Used for Keyboard
layout
Power plug Plug type/norm
HH14001601
(DE)
Germany,
Austria
DE QWERTZ KC-015A
IEC 60884-1
HH14001602
(UK)
UK, Ireland,
Cyprus,
Singapore,
Malaysia
UK QWERTY KC-036
BS 1363
HH14001603
(US)
USA, Canada US QWERTY KC-001
NEMA 5-15P UL817
HH14001604
(CN)
China US QWERTY KC-017
GB 2099/GB 1002
HH14001605
(IT)
Italy IT QWERTY CEI 23-16/VII
(CEI 23-50)
HH14001606
(ES)
Spain ES QWERTY KC-015A
IEC 60884-1
HH14001607
(FR/BL)
France,
Belgium
AZERTY KC-015A
IEC 60884-1
HH14001608
(AUS/NZ)
Australia, New
Zealand
US QWERTY AS/NZS 3112
SAA/3
HH14001609
(IL)
Israel QWERTY SI 32
IL/3
2 Requirements
20 Opera Phenix Plus – Site Readiness