Thermo Scientific CIMAREC BIOSYSTEM DIRECT User manual

Magnetic Stirrer
BIOSYSTEM DIRECT
BIOSYSTEM
Operating Manual
50134801 Issue 03.2012
TM
Directly and remote-controlled
single and multiple
magnetic stirring systems

Thermo Scientific 2 50134805_03.2012
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Contents
50134805_03.2012 3 Thermo Scientific
Table of Contents
1 User considerations...................................................................6
1.1 Correct use..........................................................................6
1.2 Incorrect use........................................................................6
1.3 Pictographs .........................................................................6
2 Safety considerations ................................................................7
3 Equipment description .............................................................10
4 Function...................................................................................11
5 Startup procedure....................................................................12
6 Stirring operation......................................................................14
6.1 Stirring vessels..................................................................14
6.2 Magnetic stirring bars........................................................15
6.3 Recommended rotation speed ranges ..............................18
6.4 Stirring...............................................................................18
7 Maintenance and cleaning.......................................................21
8 Troubleshooting.......................................................................22
9 Accessories .............................................................................24
10 Technical Specifications ..........................................................25
11 Warranty..................................................................................28

Assembly Drawings
Thermo Scientific 4 50134805_03.2012
Figure 1: Single magnetic stirring system BIOSYSTEM 1 with plug-in power supply unit.
*) Not included in scope of delivery.
Figure 2: Multiple magnetic stirring system BIOSYSTEM 4 B with control unit
BIOMODUL 40 B.
2
3
8
5
7
4
6
9
2
5
1
1
1 stirring device*
2 stirring vessel*
5 magnetic stirrer
7 control cable
8 power cable
9 control unit
1 stirring device*
2 stirring vessel*
3 power supply
4 secondary cable
5 magnetic stirrer
6 rotation speed
control button

Assembly Drawings
50134805_03.2012 5 Thermo Scientific
*) Not included in scope of delivery.
Figure 3: Control unit BIOMODUL 40 B, front view
Figure 4: Control unit BIOMODUL 40 B, back view
.
10 rotation speed indicator
11 stirring time control button
12 pause time control button
13 start/stop key
14 interval key
15 rotation direction key
16 Stirring power control
button
17 rotation speed control
button
18 power ON/OFF switch
19 power input
20 Output socket
10
11
13
12
14
15
17
16
18
19
20
5

1 User considerations
Thermo Scientific 6 50134805_03.2012
1 User considerations
1.1 Correct use
The magnetic stirring systems BIOSYSTEM DIRECT and BIOSYSTEM are designed
for stirring liquids in a laboratory or production environment. They are fitted with one,
three or four stirring points. They are specifically designed for stirring shear-sensitive
biological cultures without damaging the cells.
The stirring systems are suited to operation in the following areas:
on the laboratory bench,
in incubators,
in gas incubators (CO2incubators) with or without air humidification,
in cold chambers,
in laminar flow equipments,
in safety laboratories and sterile rooms,
directly controlled BIOSYSTEM: under water baths,
remote-controlled BIOSYSTEM in water baths.
1.2 Incorrect use
The magnetic stirring systems BIOSYSTEM DIRECT and BIOSYSTEM must not be
operated in hazardous locations.
Do not stir flammable liquids with a low boiling point.
The directly controlled magnetic stirring system BIOSYSTEM must not be operated in a
water bath.
1.3 Pictographs
You will find the following pictographs in this operating manual:


DANGER!
This sign refers to dangerous voltages.


DANGER!
This sign refers to hazardous situations.


CAUTION!
This sign indicates danger to equipment and machinery.


INFORMATION
This sign indicates easier working practices.
Indicates an operating step.


Indicates alternatives.

2 Safety considerations
50134805_03.2012 7 Thermo Scientific
2 Safety considerations
The device is compliant with the safety requirements of:
EN 61010
Low-voltage directive 73/23/EEC
EMC directive 89/336/EEC
For your own safety, you should observe the following safety warning signs.
The safety warnings indicate a possible source of danger.
At the same time they contain information on how correct action can avert danger. You
will always find warning signs attached to points of possible danger.


DANGER!
Magnetism.
Magnetic or metallic parts (e.g. data carriers, pacemakers, watches...)
can be affected by magnetic fields.
Keep such parts away from the magnetic stirrer (5) and the stirring
device (1).


DANGER!
Supply voltage and supply frequency must be within the range
specified for the power supply unit (3) or the control unit (9).


DANGER!
Defective secondary cables (4), power cables, or mains plugs must be
replaced only with original parts by the manufacturer or one of its
representatives.
Return the defective power supply unit (3) to our customer service for
repair.


DANGER
GLASS SPLINTER.
At high speeds of the mixing stick can lead to the destruction of the
sample vessels.
Wear safety goggles!
The vortex should not reach the stirring bar.
The stirring bar must rotate in the center of the sample vessel.
Watch the rotational behavior of the mixing stick for slow starts


CAUTION!
The equipment must not be operated in hazardous locations.

2 Safety considerations
Thermo Scientific 8 50134805_03.2012


CAUTION!
Permitted ambient conditions for the directly controlled BIOSYSTEM
DIRECT:
Magnetic stirrer (5): -10° to + 56°C at 100 % humidity.
Power supply unit (3): +10° to + 40°C at max. 80 % humidity.
The magnetic stirrer (5) must not be operated in a water bath.
The power supply unit (3) must not be run in humid rooms, or set up in
water splash zones.


CAUTION!
Permitted ambient conditions for the remote-controlled BIOSYSTEM :
Magnetic stirrer (5): -10° to + 56°C at 100 % humidity,
0° to + 50°C in a water bath.
Control unit (9): +10° to + 40°C at max. 80 % humidity.
The control unit (9) must not be run in humid rooms, or set up in water
splash zones.


CAUTION!
The magnetic stirring system must be switched off before connecting
or pulling the connector.
BIOSYSTEM DIRECT: The rotation speed control button (6) must
always be brought to position OFF first.
BIOSYSTEM: Switch off control unit (9) using power ON/OFF switch
(18).


CAUTION
High speed rotations of the stirring bar can cause a warming of the
goods.


CAUTION
At high speeds of the magnetic stirring, too high power setting can
lead to overheating of the stirred material.


CAUTION!
Do not place hot stirring vessels (2) on top of the magnetic stirrer (5).
Max. temperature: 56°C.


CAUTION!
Do not use cleaning agents which attack and corrode the stainless
steel surface of the magnetic stirrer (5).


CAUTION!
In case of repair, the equipment must only be opened by an authorised
service agent.

2 Safety considerations
50134805_03.2012 9 Thermo Scientific


CAUTION!
Do not allow the stirring device (1) to come to rest in an alternating
magnetic field if the device is unable to rotate. Do not subject the
stirring device (1) to a strong inverse magnetic field. This may cause
the device to become demagnetised.


CAUTION
Do not allow AlNiCo5 type magnetic stirring bars to remain in an
alternating magnetic field if they cannot rotate freely. Do not subject
the magnetic stirring bar to a strong inverse magnetic field. This may
cause the magnetic stirring bar to become demagnetized.


INFORMATION
The length of the magnetic stirring bar (2) must be smaller than the
diameter of the magnetic coupling (tech. specification).


INFORMATION
Check the box, the parts delivered on completeness and visible
damage.


INFORMATION
Use only appropriate sample containers! Review the sample containers
prior to use for visible damage (cracks, tears, splinters, leakages, etc.
...)


INFORMATION
Use only suitable and undamaged magnetic stirrers! Check the stirring
bar before use for signs of damage (cracks, chips ... etc.)
INFORMATION
Observe the relevant safety data sheets for chemical substances that
you are working in the magnetic stirrer.


INFORMATION
Read the instructions carefully before using the magnetic stirrer. No
application of the device by an untrained and inexperienced personnel.
INFORMATION
Use only in the instructions specified accessories, according to the
illustrated configuration.

3 Equipment description
Thermo Scientific 10 50134805_03.2012
3 Equipment description
Figures 1 to 5 show the components together with their position numbers.


INFORMATION
Check the box, the parts delivered on completeness and visible
damage.
The directly controlled magnetic stirring system BIOSYSTEM DIRECT is available as a
single or multiple magnetic stirrer (5) and a separate power supply unit (3).
The remote-controlled magnetic stirring system BIOSYSTEM is available as a single or
multiple magnetic stirrer (5) and a separate control unit (9).
The magnetic stirrer (5) is fitted with one, three or four stirring points. On the
BIOSYSTEM 4 DIRECT and 4, the four stirring points are arranged in a block.
Directly controlled BIOSYSTEM DIRECT:
Power is supplied via the power supply unit (3). A secondary cable (4) on the power
supply unit (3) is connected into the socket on the magnetic stirrer (5).
The rotation speed can be preset with the rotation speed control button (6). Following a
soft start, the stirring device (1) will rotate at the preset speed. To terminate the stirring
process, turn the rotation speed control button (6) slowly to position OFF. In this way
the rotation speed will be gradually reduced to zero.
Remote-controlled BIOSYSTEM:
The control cable (7) connects the magnetic stirrer (5) with the control unit (9)
BIOMODUL 40 B. The magnetic stirrer (5) is supplied with power and controlled via the
control unit (9). It is connected to the mains supply with the power cable (8).
The control unit (9) BIOMODUL 40 B has all the controls necessary for an effective
stirring operation:
rotation speed control button (17) with digital rotation speed indicator (10)
power adapted to the stirring task
reversal of rotation direction
continuous and interval operation
The stirring process is always started slowly and stopped slowly. The power ON/OFF
switch (18) for the control unit (9) BIOMODUL 40 B is located at the back of the unit..
The control unit (9) can drive up to two magnetic stirrers (5) simultaneously. Two output
sockets (20) are provided for this purpose at the back of the unit. The upper output
socket (20) is always used first.
A separate power supply for both equipment types ensures a safe low voltage situation
at the magnetic stirrer (5). Following a power failure, the magnetic stirrer (5) will come
on again automatically.
Drive and electronic control system are inside the polished stainless steel housing of
the magnetic stirrer (5), which is completely watertight. This prevents germs from
penetrating into the inside of the magnetic stirrer (5). The magnetic stirrer (5) is cleared
for use in safety laboratories and sterile rooms.
Stirring vessel (2) and stirring device (1) do not fall within the scope of delivery.