Leica AutoStainerXL User manual

Leica Autostainer XL (ST5010)
Automated slide stainer
Instructions for Use
English
Order No.: 14 0456 80101 - Revision I
Always keep this Instructions for Use with the instrument.
Read carefully before working near the instrument.
Version 3.0, Revision I - 10.2017

3
Leica Autostainer XL (ST5010)
The information, numerical data, notes and value judgments contained in this Instructions for Use
represent the current state of scientific knowledge and state-of-the-art technology as we understand it
following thorough investigation in this field.
We are under no obligation to update the present Instructions for Use periodically and on an ongoing
basis according to the latest technical developments, nor to provide our customers with additional
copies, updates etc. of this Instructions for Use.
To the extent permitted in accordance with the national legal system as applicable in each individual
case, we shall not be held liable for erroneous statements, drawings, technical illustrations etc.
contained in this Instructions for Use. In particular, no liability whatsoever is accepted for any financial
loss or consequential damage caused by or related to compliance with statements or other information
in this Instructions for Use.
Statements, drawings, illustrations and other information regarding the contents or technical details of
the present Instructions for Use are not to be considered warranted characteristics of our products.
These are determined only by the contract provisions agreed between ourselves and our customers.
Leica reserves the right to change technical specifications as well as manufacturing processes without
prior notice. Only in this way is it possible to continuously improve the technology and manufacturing
techniques used in our products.
This document is protected under copyright laws. All copyrights to this documentation are held by Leica
Biosystems Nussloch GmbH.
Any reproduction of text and illustrations (or of any parts thereof) by means of print, photocopy,
microfiche, web cam or other methods – including any electronic systems and media – requires express
prior permission in writing by Leica Biosystems Nussloch GmbH.
For the instrument serial number and year of manufacture, please refer to the nameplate on the back of
the instrument.
Note
Leica Biosystems Nussloch GmbH
Heidelberger Str. 17 - 19
D-69226 Nussloch
Germany
Tel.: +49 - (0) 6224 - 143 0
Fax: +49 - (0) 6224 - 143 268
Web: www.LeicaBiosystems.com

4Version 3.0, Revision I
Table of Contents
1. Important Information ................................................................................................................................ 6
1.1 Symbols in the text and their meaning......................................................................................................... 6
1.2 Intended use................................................................................................................................................... 10
1.3 User group ...................................................................................................................................................... 10
2. Safety .......................................................................................................................................................... 11
2.1 General safety notes..................................................................................................................................... 11
2.2 Specific safety notes..................................................................................................................................... 11
3. Instrument Features.................................................................................................................................. 14
3.1 General description....................................................................................................................................... 15
3.2 Standard delivery – packing list.................................................................................................................. 16
3.3 Specifications................................................................................................................................................. 18
4. Installing the Instrument ......................................................................................................................... 20
4.1 Installation site requirements...................................................................................................................... 20
4.2 Setting up the instrument............................................................................................................................. 21
4.3 Connections on the instrument ................................................................................................................... 21
4.3.1 Power supply.................................................................................................................................................. 21
4.3.2 Water supply .................................................................................................................................................. 21
4.4 Battery backup – UPS (optional)................................................................................................................. 22
4.5 Remote alarm (optional) ............................................................................................................................... 22
4.6 Vacuum extraction system for reagent vapors ........................................................................................ 23
4.7 Oven................................................................................................................................................................. 23
5. Operating the Instrument......................................................................................................................... 24
5.1 The control panel........................................................................................................................................... 24
5.2 Main menu...................................................................................................................................................... 26
5.3 Menu overview .............................................................................................................................................. 27
5.4 Editing programs............................................................................................................................................ 27
5.4.1 Entering program steps ................................................................................................................................ 28
5.4.2 Deleting program steps ................................................................................................................................ 29
5.4.3 Inserting a blank step into a program ........................................................................................................ 29
5.4.4 Removing blank steps from a program ...................................................................................................... 29
5.4.5 Saving a program........................................................................................................................................... 30
5.4.6 Deleting a program........................................................................................................................................ 30
5.4.7 Copying a program ........................................................................................................................................ 30
5.4.8 Viewing a program ........................................................................................................................................ 31
5.4.9 Checking the compatibility of programs.................................................................................................... 31
5.5 User-adjustable parameters........................................................................................................................ 32
5.6 Oven................................................................................................................................................................. 32
5.7 Up/down movement (dips) ........................................................................................................................... 32
5.8 Number of up/down movement (dips)........................................................................................................ 33
5.9 Staining............................................................................................................................................................ 33
5.9.1 Reagent containers....................................................................................................................................... 34
5.9.2 Wash system.................................................................................................................................................. 34
5.9.3 Water-saving function.................................................................................................................................. 34
5.9.4 Loading specimen slide holders.................................................................................................................. 34
5.9.5 Unloading specimen slide holders from the exit drawer........................................................................ 35

5
Leica Autostainer XL (ST5010)
Table of Contents
5.9.6 Unloading specimen slide holders from other stations .......................................................................... 36
5.9.7 Interrupting staining...................................................................................................................................... 36
5.9.8 Aborting the processing of a specimen slide holder............................................................................... 37
6. Care and Cleaning .................................................................................................................................... 38
6.1 Wash containers............................................................................................................................................ 38
6.2 Reagent containers....................................................................................................................................... 38
6.3 Specimen slide holders ................................................................................................................................ 38
6.4 Oven................................................................................................................................................................. 38
6.5 Water drainage.............................................................................................................................................. 39
7. Error Messages and Troubleshooting................................................................................................... 40
7.1 Warning messages for instrument errors ................................................................................................. 40
7.2 More information and warnings.................................................................................................................. 41
7.2.1 During staining............................................................................................................................................... 41
7.2.2 During editing of programs .......................................................................................................................... 41
7.2.3 During SetUp .................................................................................................................................................. 41
8. Warranty and Service .............................................................................................................................. 42
9. Decommissioning and disposal............................................................................................................. 43
10. Decontamination Confirmation.............................................................................................................. 44
11. Appendix .................................................................................................................................................... 45
11.1 Adjustable parameters ................................................................................................................................. 45
11.2 Consumables and accessories ................................................................................................................... 45
11.3 Compatible staining programs..................................................................................................................... 47

6Version 3.0, Revision I
Important Information
1
1. Important Information
General information
These Instructions for Use include important instructions and information related to the operating safety
and maintenance of the instrument.
The Instructions for Use are an important part of the product. They must be read carefully prior to
startup and use, and must always be kept near the instrument.
If additional requirements for accident prevention and environmental protection apply in the country
of operation, these Instructions for Use must be supplemented by appropriate instructions to ensure
compliance with such requirements.
Make sure to read all of these Instructions for Use before you work on or operate the instrument.
Warning
Be sure to comply with the safety instructions and warnings in (→p. 11 – 2. Safety). Be sure to
read these notes even if you are already familiar with the operation and use of other Leica products.
1.1 Symbols in the text and their meaning
Symbol: Title of the symbol: Warning
Description: Warnings appear in a white box and are marked by a
warning triangle.
Symbol: Title of the symbol: Note
Description: Useful tips, i.e. important information for the user,
appear in white boxes and are marked by an
information symbol.
Symbol: Title of the symbol: Item number
→"Fig. 7 - 1"Description: Numbers in parentheses refer to item numbers in
illustrations or to the illustrations themselves.
Instrument type
All information in these Instructions for Use applies only to the Leica Autostainer XL (ST5010) described
here.
A nameplate indicating the instrument serial number is attached to the rear of the instrument.
Note
(→Fig. 1) is provided as an example only and shows a valid nameplate for this instrument with
the necessary information about instrument type and power requirement. The precise data for the
various versions is specified in (→p. 18 – 3.3 Specifications).

7
Leica Autostainer XL (ST5010)
Important Information
1
Fig. 1
Symbol: Title of the symbol: In vitro diagnostic medical device
Description: Indicates a medical device that is intended to be
used as an in vitro diagnostic medical device.
Symbol: Title of the symbol: Consult Instructions for Use
Description: Indicates the need for the user to consult the
Instructions for Use.
Symbol: Title of the symbol: China ROHS
Description: Environmental protection symbol of the China RoHS
directive. The number in the symbol indicates the
"Environment-friendly Use Period" of the product in
years.
Symbol: Title of the symbol: WEEE Symbol
Description: The WEEE (Waste Electrical and Electronic
Equipment) symbol, indicating separate collection
of electrical and electronic equipment, consists of a
crossed-out wheeled bin (§ 7 ElektroG).
Symbol: Title of the symbol: CE Compliance
Description: The CE marking is the manufacturer's declaration
that the medical product meets the requirements of
the applicable EC directives.
Symbol: Title of the symbol: Caution
Description: Indicates the need for the user to consult the
Instructions for Use for important cautionary
information such as warnings and precautions that
cannot, for a variety of reasons, be presented on the
medical device itself.
Symbol: Title of the symbol: Caution – Moving parts
Description: Label is attached on the transport arm. It indicates a risk
of collision between the transport arm and any operator
working within the instrument while the transport arm
is moving.

8Version 3.0, Revision I
Important Information
1
Symbols: Title of the symbol: Caution – Toxic chemicals / Flamable substances
Description: Labels are attached inside the instrument below the
fixation of the hood (in the middle).
The first label indicates that toxic chemicals are inside
the instrument. Do not handle solution containers un-
less properly protected.
The second label indicates that there is a risk of fire
because of flamable substances inside the instrument.
Thus, avoid any source of ignition close to the instru-
ment.
Symbol: Title of the symbol: Caution – Hot surface
Description: Two labels are attached close to the oven. They
indicate a risk of burns because of hot surfaces. Do
not touch these parts.
Symbol: Title of the symbol: Caution – Risk of fire
Description: Label is attached at the rear of the instrument close
to the fuse. It indicates a risk of fire in case that no or
inappropriate fuses are used. For continued protection
against the risk of fire replace only with appropriate
fuses as indicated on the instrument.
Symbol: Title of the symbol: Caution – Input voltage
Description: Label is attached at the rear of the instrument above
the switched mains power inlet. It indicates that the
unit is wired either for 100-120 VAC or 230-240 VAC
(depending on your order). Do not change wiring or
voltage selection on your own but contact qualified
Leica service personnel in this case.
Symbol: Title of the symbol: Caution – Water supply and interfaces
Description: Labels are attached at the rear of the instrument close
to the serial port and the water supply connections.
They indicate that both Instructions for Use and – if
applicable – any inscription on the instrument must
be observed.
Symbol: Title of the symbol: CSA Statement (Canada/USA)
Description: The CSA test mark means that a product has been
tested and fulfills the applicable safety standards.
Symbol: Title of the symbol: Serial number
Description: Indicates the manufacturer's serial number so that a
specific medical device can be identified.
Symbol: Title of the symbol: Article number
Description: Indicates the manufacturer's catalog number so that
the medical device can be identified.

9
Leica Autostainer XL (ST5010)
Important Information
1
Symbol: Title of the symbol: Manufacturing date
Description: Indicates the date when the medical device was
manufactured.
Symbol: Title of the symbol: Manufacturer
Description: Indicates the manufacturer of the medical product.
Symbol: Title of the symbol: This way up
Description: Indicates correct upright position of the transport
package.
Symbol: Title of the symbol: Store dry
Description: Indicates a medical device that needs to be
protected from moisture.
Symbol: Title of the symbol: Fragile, handle with care
Description: Indicates a medical device that can be broken or
damaged if not handled carefully.
Symbol: Title of the symbol: Tilt indicator
Description: Indicator to monitor whether the shipment has been
transported and stored in upright position according
to your requirements. With a pitch of 60° or more,
the blue quartz sand flows into the arrow-shaped
indicator window and sticks there permanently.
Improper handling of the shipment is immediately
detectable and can be proven definitively.
Symbol: Title of the symbol: IPPC symbol
Description: The IPPC symbol includes IPPC symbol
• Country code to ISO 3166, e.g. DE for Germany
• Regional identifier, e.g. NW for North
Rhine-Westphalia
• Registration number, unique number beginning
with 49.
• Treatment method, e.g. HT (heat treatment)

10 Version 3.0, Revision I
Important Information
1
Symbol: Title of the symbol: ON / STOP (Power)
Description: ON: The electronic power supply is connected upon
pushing the power switch.
STOP: The electronic power supply is disconnected
upon pushing the power switch.
Label is attached close to the electronic power supply
switch.
1.2 Intended use
The Leica Autostainer XL (ST5010) is an IVD (in-vitro diagnostics) instrument. The
Leica Autostainer XL (ST5010) is a stainer for laboratory applications and intended for the preparation of
histological and cytological tissue samples.
Danger
Any use of the instrument that deviates from the designated use is considered improper.
Failure to adhere to these instructions may result in an accident, personal injury, damage to
the instrument or accessory equipment. Proper and intended use includes compliance with all
inspection and maintenance instructions, along with the observance of all instructions in the
Instructions for Use as well as the constant inspection of the reagents for storage life and quality.
The Leica Autostainer XL (ST5010) carries out the specified staining steps automatically. The
manufacturer assumes no liability for the staining results in the case that the staining steps and
programs are entered incorrectly. Thus, the end user is independently responsible for self-created
reagents or program entries.
1.3 User group
• The Leica Autostainer XL (ST5010) should be operated by trained laboratory personnel only.
• All laboratory personnel designated to operate the Leica Autostainer XL (ST5010) must read these
Instructions for Use carefully and must be familiar with all technical features of the instrument before
attempting to operate the Leica Autostainer XL (ST5010).
Note
To prevent damage to the instrument and specimens, only those accessories and spare parts that
have been authorized by Leica may be installed or used with the instrument.

11
Leica Autostainer XL (ST5010)
Safety
2
2. Safety
2.1 General safety notes
This instrument has been built and tested in accordance with the safety requirements for electrical
equipment for measurement, control and laboratory use.
To maintain this condition and ensure safe operation, the user must observe all notes and warnings
contained in these Instructions for Use.
For current information about applicable standards, please refer to the CE Declaration of Conformity on
our Internet site:
www.LeicaBiosystems.com
2.2 Specific safety notes
Warning
Operating the instrument without adequate clothing
Personal injury
• Always wear protective clothing suitable for laboratory use, as well as rubber gloves and safety
goggles when handling the chemicals used in this instrument.
• Always follow your laboratory safety regulations.
Warning
Breathing in vapors dangerous to health
Personal injury
• Connect the instrument to a laboratory air exhaust system using the dedicated hose (lenghts of
2 m and 4 m available). Alternatively the instrument can be operated below a fume cupboard. This
should be run in addition to the active carbon filter.
Warning
Contamination after accidential handling of reagents
Insufficient staining quality or complete loss of tissue
• If you have accidentially contaminated reagents, e.g., because a reagent has dripped into
another vessel always follow your local regulations. Focus on saving the tissue first. Dispose any
contaminated reagents and clean the affected vessels thoroughly.
Caution
Vessels not cleaned or cleaned insufficiently before refilling with another reagent
Insufficient staining quality, tissue damage or loss of tissue
• Always clean the vessels thoroughly and regularly before refilling them (→p. 38 – 6.2 Reagent
containers).

12 Version 3.0, Revision I
Safety
2
Caution
Inadequate manual loading of specimen slide holders into vessels
Loss of tissue and / or property damage because of crash due to automized loading of another
specimen slide holder into the same vessel
• Do not manually load specimen slide holders and start any movement of the transport arm
Caution
Lids not removed from vessel
Loss of tissue and / or property damage because of crash due to automized loading of a specimen
slide holder
• Always make sure that any lids are removed before initiating any transport to the affected vessel.
Caution
Specimen slide holders are loaded unintentionally into exit drawer instead of the load drawer.
Delay of processing time / Damage or loss of tissue
• Always pay attention to load specimen slide holders into the load drawer (→p. 34 – 5.9.4
Loading specimen slide holders).
Caution
Reagent filling level within vessels is insufficient
Loss of tissue and / or property damage because of crash due to automized loading of a specimen
slide holder
• Check the filling level of the vessels regularly and clean and / or refill if required.
• Cover unused vessels to minimize evaporation.
Caution
Water drainage not cleaned or cleaned insufficiently
Insufficient staining quality, loss of tissue or property damage
• Check and clean the draining system regularly for correct flow.
Caution
Specimen slide holders not unloaded in a timely manner from exit drawer
Delay of processing time / Damage or loss of tissue
• Unload the exit drawer in time, close the exit drawer and press EXIT (→p. 35 – 5.9.5 Unloading
specimen slide holders from the exit drawer).
Caution
Specimen slide holder processed with wrong program parameters
Damage or loss of tissue
• Always double-check program parameters of user-specific programs before you start
processing.

13
Leica Autostainer XL (ST5010)
Safety
2
Warning
In accordance with national rules and regulations, the operator may be obligated to provide long-
term protection of the public water supply from contamination due to backflowing water from
the building installation. In Europe, the protection device of the potable water installation to be
connected is selected in accordance with the specifications of DIN EN 1717:2011-08 (information
status August 2013).

14 Version 3.0, Revision I
Instrument Features
3
3. Instrument Features
General description
The Leica Autostainer XL (ST5010) was developed with the goal of satisfying the quality requirements of
modern laboratories:
• high specimen throughput,
• flexibility,
• safety.
The Leica Autostainer XL (ST5010) achieves its high throughput by means of a specimen slide transport
system, which allows for simultaneous processing of up to 11 specimen slide holders, each with 30
slides.
The flexibility of Leica Autostainer XL (ST5010) permits simultaneous processing of specimen slide
holders according to various staining protocols.
An oven is integrated into the instrument which accelerates drying of specimen slides. Optimized wash
stations provide for rapid removal of reagent residue. The design of the specimen slide holders ensures
minimal reagent displacement and prevents the reagents from being contaminated by liquid dripping
into them and needing to be replaced prematurely.
The Leica Autostainer XL (ST5010) is safe to use and has an integrated system for extracting reagent
vapors. The specimen slide holders are loaded and unloaded using two drawers.

15
Leica Autostainer XL (ST5010)
Instrument Features
3
3.1 General description
Fig. 2
1
6
11
16
21
2
7
12
17
3
8
13
18
4
9
14
19
5
10
15
20
Front side of instrument
1Transport arm 12 Reagent container
2Wash stations 13 Load drawer
3Oven 14 LED indicator and key for load drawer
4Notepad for staining protocols 15 Exit drawer
5Recess for notepad 16 Cover with cut-outs (for container transportation)
6ON/STOP switch 17 LED indicator and key for exit drawer
7Display screen 18 Schematic diagram of the stations
8Keypad 19 Cover plate
9LED indicators 20 Lock for hood1)
10 Specimen slide holder 21 Hood
11 Container cover
1) The lock for the hood contains a gas pressure spring. This part can wear out. In case of weakening
holding force, please contact our after-sales service and ask for replacement.

16 Version 3.0, Revision I
Instrument Features
3
Fig. 3
1
6 11 2 7 123 81349145 10
Rear side of instrument
1Water inlet 8Feet, adjustable
2Drain outlet 9Power supply input
3Serial port (service computer) 10 Nameplate
4Power supply (electronics) 11 Remote alarm socket, max. 50 V, 1 A
5Voltage selector and fuses for heater 12 Accessory port
6Power switch (ON/OFF) 13 Exhaust air duct
7Power input 14 Power output
3.2 Standard delivery – packing list
Note
To prevent damage to the instrument and specimens, only those accessories and spare parts that
have been authorized by Leica may be installed or used with the instrument.
Standard delivery:
Qty. Designation Order No.
1Leica Autostainer XL (ST5010) basic unit (230-240 V / 50-60
Hz)
14 0456 35136
- or -
1Leica Autostainer XL (ST5010) basic unit (100-120 V / 50-60
Hz)
14 0456 35340
1 accessories kit (0456 35660) consisting of:
22 reagent vessels with lids 14 0475 33659

17
Leica Autostainer XL (ST5010)
Instrument Features
3
Qty. Designation Order No.
5 wash vessels 14 0456 35268
5 specimen slide holders, metal 14 0456 33919
2 covers with slots for reagent vessels 14 0475 34486
1 jumper cable, power supply 14 0411 34604
1 remote alarm connector 14 6844 01005
1 tubing band clamp 14 0422 31972
1 angular connecting nozzle for hose 14 0475 33669
1 V filter 3/4. 14 0456 36101
1 active carbon filter 14 0474 32273
1 filter cover 14 0456 35240
1 collecting tray for paraffin (heater) (inside the instrument) 14 0456 35216
1 staining protocol notepad (attached to instrument) 14 0456 35459
1 water supply hose with seal 14 0474 32325
1 drain hose 14 0475 35748
1 Instructions for Use Leica Autostainer XL (ST5010) German/
English (+CD)
14 0456 80001
1 reference manual as appendix, only in English (staining
protocols, etc.)
The country specific power cord needs to be ordered separately. Please find a list of all power cords
available for your device on our website www.LeicaBiosystems.com within the product section.

18 Version 3.0, Revision I
Instrument Features
3
3.3 Specifications
Dimensions (width x depth x height): 109 cm x 67 cm x 51 cm
Weight: 65 kg
Nominal supply voltages: 100-120V AC ± 10% or 230-240V AC ± 10 %
Nominal frequency: 50-60 Hz
Power draw: 650 VA
Fuses: 5 x 20 mm, VDE / UL listed
100-120 V: quick acting fuse F 6.30 A L250 VAC
230-240 V; quick acting fuse F 3.15 A L250 VAC
IEC 1010 classification: Protection class 1
Overvoltage category: II
Pollution degree: 2
International protection class: IP20
A-weighted noise level: ≤70dB(A)
Performance parameters
Slide throughput depending on selected protocol:
max. 600 slides /h
min. 200 slides /h
Loading capacity: max. 11 specimen slide holders
Capacity of one specimen slide
holder:
30 slides
Overall number of stations: 26
Reagent stations: min. 18
Volume of reagent vessels: 450 ml
Overall number fo water stations: max. 5 (DI water optional)
Number of oven chambers: 1
Temperature of oven chamber: Ambient temperature or +30 to +65 °C
Incubation time setting: 0 s to 99 min 59 s
Overall number of loading / unloading
stations:
1 / 1
Capacity of nonvolatile storage: 15 programs with up to 25 steps
Integration: Connection with CV5030 (coverslipper, optional)
Fresh water connection
Hose material: PVC
Hose length: 2.5 m
Connecting piece: G3/8
Inner diameter: 10 mm
Outer diameter: 16 mm
Internal pressure: Min. 1 bar / max. 6 bar
Required flow rate: Min. 12 l/ min

19
Leica Autostainer XL (ST5010)
Instrument Features
3
Waste water connection
Hose material: PVC
Hose length: 4 m
Inner diameter: 32 mm
Outer diameter: 36.8 mm
Exhaust air
Hose material: PVC
Hose length: 2 m or 4 m
Inner diameter: 50 mm
Outer diameter: 60 mm
Exhaust performance: 22.4 m3/h
Exhaust extraction: Active carbon filter and exhaust hose for connecting with an
external exhaust system
Ambient conditions
Operating temperature: 15 to 35 °C
Operating relative humidity: 20 % to 80 %, non-condensing
Operating elevation: Max. 2000 m above sea level
Storage temperature: +5 to +50 °C
Storage relative humidity: 10 % to 85%, non-condensing
Transport temperature: -29 °C to +50 °C
Transport relative humidity: 10 % to 85%, non-condensing

20 Version 3.0, Revision I
Installing the Instrument
4
4. Installing the Instrument
This chapter provides instructions on how to install the Leica Autostainer XL (ST5010). It also includes
a diagram and detailed description of the instrument's components. The procedure for replacing the
active carbon filter for protection against reagent vapors is outlined as well.
4.1 Installation site requirements
• Required hard surface: 1.09 x 0.67 m2
• The laboratory bench must be of sufficient bearing capacity relating to the instrument and must have
a rigid surface.
• The device is intened for indoor use only
• The next power socket must not be further away than the length of the power cord (2.5 m)). Use of an
extension cord is not allowed.
• The instrument needs to be connected to a grounded power supply socket.
• Use only the provided power cord intended for the local power supply
• The instrument must not be installed below any air conditioning system
• Any shaking, direct sunlight and significant current fluctuations need to be avoided
• Proper function is ensured only if a minmum distance of 10 cm is respected towards all walls and any
other fixtures
• The instrument need to be installed in a way that allows easy access to the power switch and the
power plug at the rear side.
• Operation is not allowed in any areas exposed to explosion hazards
• The installation site needs to be protected against electrostatic discharges
• The installation site needs to be well ventilated because chemicals used within the instrument are
highly flammable and unhealty
• Connect the instrument to a laboratory air exhaust system using the dedicated hose (lenghts of 2 m
and 4 m available). Alternatively the instrument can be operated below a fume cupboard. This should
be run in addition to the active carbon filter.
• Please consider that the active carbon filter supports only filtration of hazardous vapors (Xylene)
• The situation at the installation site may vary significantly and depends on existing ventilation,
emissions of other installed devices, the use of solvents, the volume of the room, etc.
• It is the responsibilty of the laboratory owner / laboratory operator to not exceed the legal maximum
permissible values and to take all measures at the working places regarding the solvent vapors. This
includes also corresponding documentation.
• The operator of the instrument needs to make sure that sufficient ventilation is ensured and the
active carbon filter is replaced within the required interval.
• The voltage selector and other internal components are preset by the manufacturer to meet the
power requirements of the respective country of destination.
Warning
The user must not alter the voltage selector setting.
• The Leica Autostainer XL (ST5010) must be connected to a laboratory water tap with a pressure
reducer.