Advantech MIO-5376 Installation and operation manual

MIO-5376 Startup Manual 1
Before you begin installing your card, please make sure that
the following items have been shipped:
1. 1 x SATA cable, 30 cm (P/N: 1700006291)
2. 1 x SATA power cable, 35 cm (P/N: 1700031583-01)
3. 1 x USB 2.0 cable, 20 cm (P/N: 1700030406-01)
4. 1 x USB 3.2 cable, 35 cm (P/N: 1700032181-01)
5. 1 x Audio cable, 20 cm (P/N: 1700019584-01)
6. 2 x COM RS-232/422/485 cables, 20 cm (P/N:
1700030404-01)
7. 2 x COM RS-232 cables, 20 cm (P/N: 1700031582-01)
8. 1 x Heatsink for 12W/15W(P/N:1970005548T001)
9. 1 x Screw kit (2 sets of screws for the M.2 device & 4
sets of screws and stand-o󰀨 for the heatsink/cooler)
If any of the above items are missing or damaged, contact
your distributor or sales representative immediately.
Note 1: For detailed contents of MIO-5376, please refer
to information on the support website: http://sup-
port.advantech.com.tw
Note 2: Adobe Reader is required to view any PDF le.
Adobe Reader can be downloaded at: http://get.
adobe.com/tw/reader/otherversions. (Adobe is a
trademark of Adobe Systems Incorporated.)
MIO-5376 3.5” MI/O-Compact SBC, AMD Ryzen™
Embedded R2000 Series, DDR4, 3xGbE,
PoE 802.3af, HDMI, DP, CANBus, M.2 2230/80,
M.2 3042/52, DC-In 12-24V, & iManager
Startup Manual
General
• CPU:
- R2314 SoC with AMD Radeon™ Graphics
- R2514 SoC with AMD Radeon™ Graphics
• System Memory: Dual Channel/SODIMM DDR4-2666
MT/s, up to 32GB
• BIOS: AMI EFI 256 Mbit
• Watchdog timer: 65536 levels, 0~65535 sec
• iManager 3.0: Yes
• Battery: Lithium 3V/210mAH
• Audio: Supports High Denition Audio (HD), Line-In,
Line-Out, and Mic-In.
Expansion Interface
• 1x M.2 E-Key 2230 module (PCIe x1, USB 2.0 to support
a wireless module)
• 1 x M.2 B-Key 3042/3052 module (PCIe x1, USB 3.2/2.0
to support a 5G_GNSS/LTE module)
• 1 x M.2 M-Key 2280 module (PCIe Gen3 x4, optional
SATA)
Display
• Controller: Integrated AMD Radeon Graphics
• Maximum resolution:
- 1 x LVDS dual channel 18/24-bit LVDS up to 1920 x
1200
- 1 x HDMI2.0 up to 4Kx2Kx24 bpp @60Hz
- 1 x DP1.4 up to 4096x2304x36 bpp @60Hz
• Multiple displays: 3 simultaneous displays
Ethernet Interface
• Max. Speed: 2.5Gbe/port
• Controller: 3 x Intel® i226
• PoE (Optional): LAN2 & LAN3 port features PoE sup-
port 802.3af 15.4W/port with optional MIOe-PSE power
module.
I/O
• Internal I/O: 1 x SATA, 2 x USB 2.0, 2 x USB 3.2, 2 x
RS-232/422/485, 2 x RS-232, 1x I2C/SMB (optional), 8-bit
GPIO, Inverter, HD Audio, 1 x CANBus 2.0
• Rear I/O: 3 x RJ-45, 1 x HDMI, 2 x USB 3.2, 1 x DP
• Power connector type: 2-pin phoenix connector
Mechanical and Environmental
• Dimensions (L x W): 146 x 102 mm (5.7” x 4”)
• Power requirement: Vin: 12 V-24 V ±10%
• Operating temperature:
- Standard: 0 ~ 60 °C (32 ~ 140 °F)
- Extended: -40 ~ 85° C (-40 ~ 185 °F)
Specications
Packing List
For more information about this and other Advantech
products, visit our website at:
http://www.advantech.com
http://www.advantech.com/eplatform
For technical support and customer service, visit our
support website at:
http://support.advantech.com.tw
This manual is for the MIO-5376 series.
Part No. 2046537600
Printed in China
Edition 1
Mar. 2023

2 MIO-5376 Startup Manual
The board has a number of jumpers that allow you to congure
your system to suit your application. The table below lists the
functions of each of the jumpers and connectors.
Jumpers
Label Function
J1 AT mode / Load BIOS default
VDD1 LCD Power Setting
No. Location Description
1 CN2 I2C/SMBus Internal Connector
2 FAN1 Smart FAN Internal Connector
3 COM3 COM-Port Internal Connector 3
4 COM4 COM-Port Internal Connector 4
5 USB1 USB3.2 Dual-Port Connector
6 DIMM2 DDR4 SODIMM Connector 2
7 DIMM1 DDR4 SODIMM Connector 1
8 HDMI1 HDMI Connector
9 DP1 Display Connector
10 LAN3 RJ-45 LAN Port Connector 3
(Alt POE)
11 LAN2 RJ-45 LAN Port Connector 2
(Alt POE)
12 POE_PWR1 POE Power Internal Connector
13 LAN1 RJ-45 LAN Port Connector 1
14 DCIN1 DC Power Input Connector
15 COM1 COM-Port Internal Connector 1
16 COM2 COM-Port Internal Connector 2
17 CN1 Front Panel Internal Connector
18 GPIO1 GPIO Internal Connector
19 USB3 USB 2.0 Dual-Ports Internal
Connector
20 AUDIO1 Audio Internal Connector
21 CN3 CANBus Internal Connector
22 SATA_PWR1 SATA Power Connector
23 BL1 Panel Inverter Connector
24 USB2 USB 3.2 Dual-Port Internal
Connector
25 SATA1 SATA Connector
26 LVDS1 LVDS Connector
27 VDD1 Panel Voltage Selection Jumper
28 J1 Miscellaneous Selection Jumper
29 BAT1 RTC Battery Connector
Jumpers and Connectors (Cont.)
30 M2_E1 M.2 E-Key Connector
31 M2_M1 M.2 M-Key Connector
32 M2_B1 M.2 B-Key Connector
[3042/3052 Co-Lay]
33 SIM1 SIM (Subscriber Identity Mod-
ule) Card
J1 AT Mode / Load BIOS Default
Setting Function
1-2 On: AT mode* (default)
O󰀨: ATX mode
3-4 On: Reserved* (default)
O󰀨: Reserved
5-6 On: Load BIOS default
O󰀨: Normal* (default)
VDD1 LCD Power Settings
Setting Function
1-3 +3.3V (*default)
3-5 +5V
3-4 +12V
Caution! The computer is provided with a battery-powered
real-time clock circuit. Batteries are at risk of ex-
ploding if incorrectly replaced. Replace only with
the same or equivalent type as recommended by
the manufacturer. Discard used batteries accord-
ing to the manufacturer’s instructions.
Jumpers and Connectors

MIO-5376 Startup Manual 3
Connector Locations
Figure 1. Connector Locations (Top)
Figure 2: MIO-5376 Connector Locations (Top Side)
Figure 2: MIO-5376 Connector Locations (Bottom Side)
Figure 3: MIO-5376 Connector Locations (Coastline)

4 MIO-5376 Startup Manual
Figure 4: MIO-5376 Mechanical Diagram (Top Side)
Figure 5: MIO-5376 Mechanical Diagram (Bottom Side)
Figure 6: MIO-5376 Mechanical Diagram (Coastline)
Mechanical Diagram

MIO-5376 Startup Manual 5
Figure 7: MIO-5376 Mechanical Diagram (with Heatsink)
Figure 8: MIO-5376 Mechanical Diagram (with Optional Cooler)
1. Retreive the Heatsink from the accessory box. Remove the release paper from the thermal pads.
2. There are four screws on the Heatsink/Cooler/Heat Spreader. Follow the installation sequence demonstrated below to
secure the heatsink:
Mechanical Diagram (Cont.)
Quick Installation Guide

6 MIO-5376 Startup Manual
Quick Installation Guide (Cont.)
Figure 9: MIO-5376 Cooler Assembly Guide
Figure 10: MIO-5376 Heat Spreader Assembly Guide (Optional)
Figure 11: MIO-5376 PoE Module Assembly Guide (Optional MIOe-PSE module)